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Abatacept (Cytotoxic T Lymphocyte Antigen 4-Fragment Crystallizable) Reduces Allergic Inflammation of Ovalbumin-Sensitized Mice.
Abatacept (Cytotoxic T Lymphocyte Antigen 4-Fragment Crystallizable) Reduces Allergic Inflammation of Ovalbumin-Sensitized Mice.
BackgroundAbatacept (Aba) is a cytotoxic T-lymphocyte antigen-4 and fragment crystallizable fusion protein. Aba blocks B7/...
Co-Expression and Localization of Angiotensin-Converting Enzyme-2 (ACE2) and the Transmembrane Serine Protease 2 (TMPRSS2) in Paranasal Ciliated Epithelium of Patients with Chronic Rhinosinusitis
Co-Expression and Localization of Angiotensin-Converting Enzyme-2 (ACE2) and the Transmembrane Serine Protease 2 (TMPRSS2) in Paranasal Ciliated Epithelium of Patients with Chronic Rhinosinusitis
BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses angiotensin-converting enzyme-2 (ACE2) and the...
Investigation of Repeatability of Peak Nasal Inspiratory Flow Rate Measurements Under Baseline Conditions and After Administration of 0.05% Oxymetazoline
Investigation of Repeatability of Peak Nasal Inspiratory Flow Rate Measurements Under Baseline Conditions and After Administration of 0.05% Oxymetazoline
ObjectivesPeak nasal inspiratory flow (PNIF) measurement is an inexpensive and user-friendly method to assess nasal patenc...
Assessment of Biomarker Heterogeneity in Sinus Versus Inferior Turbinate Tissue in Patients Without Chronic Rhinosinusitis
Assessment of Biomarker Heterogeneity in Sinus Versus Inferior Turbinate Tissue in Patients Without Chronic Rhinosinusitis
BackgroundCurrently, no consensus exists on the appropriate control specimen site to utilize in studies evaluating for bio...
Comorbidities Known to Affect Physical Function Negatively Impact Baseline Health-Related Quality-of-Life in Patients With Chronic Rhinosinusitis
Comorbidities Known to Affect Physical Function Negatively Impact Baseline Health-Related Quality-of-Life in Patients With Chronic Rhinosinusitis
BackgroundMedical comorbidities are commonly encountered in chronic rhinosinusitis (CRS) and may impact both physical func...
Long Term Outcomes of Nasoseptal Perforation Repair With an Anterior Ethmoidal Artery Flap
Long Term Outcomes of Nasoseptal Perforation Repair With an Anterior Ethmoidal Artery Flap
BackgroundNasoseptal perforation repair is a challenging condition with no standard technique for repair recognized.Method...
Identification of Heat Shock Protein 90 as a Recurrence Related Marker in Juvenile Nasopharyngeal Angiofibroma
Identification of Heat Shock Protein 90 as a Recurrence Related Marker in Juvenile Nasopharyngeal Angiofibroma
BackgroundJuvenile nasopharyngeal angiofibroma (JNA) is a highly recurrent tumor after curative surgery.ObjectiveThe purpo...
Changes in Sleep Quality Following Treatment for Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis
Changes in Sleep Quality Following Treatment for Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis
BackgroundChronic rhinosinusitis (CRS) presents with broad and systemic manifestations, including impaired sleep; however,...
Airway Nitric Oxide in Children with HDM-Induced Allergic Rhinitis
Airway Nitric Oxide in Children with HDM-Induced Allergic Rhinitis
BackgroundRhinitis is a common problem in children. Airway nitric oxide (NO) was proposed to represent eosinophilic inflam...
Trends in Academic Achievement Within Otolaryngology: Does Fellowship Training Impact Research Productivity?
Trends in Academic Achievement Within Otolaryngology: Does Fellowship Training Impact Research Productivity?
BackgroundScholarly productivity and research output vary among different subspecialties. The h-index was developed as a m...
Opiate Use After Endoscopic Endonasal Transsphenoidal Surgery
Opiate Use After Endoscopic Endonasal Transsphenoidal Surgery
BackgroundThe literature on opiate use after endoscopic endonasal transsphenoidal surgery (EETS) is limited.ObjectiveTo de...
Reflecting on the Work of the Giants That Come Before You
Reflecting on the Work of the Giants That Come Before You
1. Zocchi, J, Russo, F, Volpi, L, et al. Long term outcomes of nasoseptal perforation repair With an anterior ethmoidal ar...
Nasal Nitric Oxide and Nasal Cytology as Predictive Markers of Short-Term Sublingual Allergen-Specific Immunotherapy Efficacy in Children with Allergic Rhinitis
Nasal Nitric Oxide and Nasal Cytology as Predictive Markers of Short-Term Sublingual Allergen-Specific Immunotherapy Efficacy in Children with Allergic Rhinitis
BackgroundFew studies have been conducted on the short-term response to sublingual immunotherapy (SLIT).ObjectiveThe purpo...
Diagnosis and Localization of Cerebrospinal Fluid Rhinorrhea: A Systematic Review
Diagnosis and Localization of Cerebrospinal Fluid Rhinorrhea: A Systematic Review
BackgroundCerebrospinal fluid (CSF) rhinorrhea results from abnormal communications between the subarachnoid and sinonasal...
Effects of Acute Alcohol Intake on Nasal Patency
Effects of Acute Alcohol Intake on Nasal Patency
BackgroundAcute alcohol intake may influence nasal patency; however, there is lack of objective evidence.ObjectiveThe aim ...
Demographic Variation in Chronic Rhinosinusitis by Subtype and Region: A Systematic Review
Demographic Variation in Chronic Rhinosinusitis by Subtype and Region: A Systematic Review
BackgroundChronic rhinosinusitis (CRS) describes a heterogenous group of diseases including CRS with (CRSwNP) or without n...
Endoscopic Sinus Surgery for Cystic Fibrosis: Variables Influencing Sinonasal and Pulmonary Outcomes
Endoscopic Sinus Surgery for Cystic Fibrosis: Variables Influencing Sinonasal and Pulmonary Outcomes
BackgroundEndoscopic sinus surgery is a well-established treatment for chronic rhinosinusitis in patients with cystic fibr...
Comparison of Electrocoagulation Tuboplasty and Continued Medical Therapy for Treating Persistent Eustachian Tube Dysfunction With Hypertrophic Mucosa Disease
Comparison of Electrocoagulation Tuboplasty and Continued Medical Therapy for Treating Persistent Eustachian Tube Dysfunction With Hypertrophic Mucosa Disease
ObjectivesThe objective of this trial was to compare outcomes of electrocoagulation tuboplasty and continued medical thera...
Effectiveness of the Endoscopic Prelacrimal Recess Approach for Maxillary Sinus Inverted Papilloma Removal: A Systematic Review and Meta-Analysis
Effectiveness of the Endoscopic Prelacrimal Recess Approach for Maxillary Sinus Inverted Papilloma Removal: A Systematic Review and Meta-Analysis
BackgroundConventional minimally invasive surgery has a high recurrence rate, and nasal morbidity can occur if the scope o...
Increased Anti-Allergic Effects of Secretome of Low-Level Light Treated Tonsil-Derived Mesenchymal Stem Cells in Allergic Rhinitis Mouse Model
Increased Anti-Allergic Effects of Secretome of Low-Level Light Treated Tonsil-Derived Mesenchymal Stem Cells in Allergic Rhinitis Mouse Model
BackgroundLow-level light therapy (LLLT) is widely used for the photobiomodulation of cell behavior. Recent studies have s...
To Think Outside the Box Requires Stepping Outside of Your Comfort Zone
To Think Outside the Box Requires Stepping Outside of Your Comfort Zone
1. Jiang, Z, Xiao, H, Liu, S, et al. Changes in immunologic indicators during allergen-specific immunotherapy for allergic...
LncRNA MIAT Promotes Allergic Inflammation and Symptoms by Targeting MiR-10b-5p in Allergic Rhinitis Mice
LncRNA MIAT Promotes Allergic Inflammation and Symptoms by Targeting MiR-10b-5p in Allergic Rhinitis Mice
BackgroundAllergic rhinitis (AR) is one of the most common noninfectious respiratory diseases caused by immunoglobulin E (...
Olfactory-related Quality of Life Adjustments in Smell Loss during the Coronavirus-19 Pandemic
Olfactory-related Quality of Life Adjustments in Smell Loss during the Coronavirus-19 Pandemic
BackgroundPrevious studies provided the first evidence that the importance of olfaction decreases with the duration of olf...
Cystic Fibrosis Increases Long-Term Revision Rates of Endoscopic Sinus Surgery in Patients With Comorbid Chronic Rhinosinusitis
Cystic Fibrosis Increases Long-Term Revision Rates of Endoscopic Sinus Surgery in Patients With Comorbid Chronic Rhinosinusitis
Background: Comorbid chronic rhinosinusitis (CRS) of adulthood is increasing among patients with cystic fibrosis (CF) due ...
Efficacy and Safety of Subcutaneous Immunotherapy for Local Allergic Rhinitis: A Meta-Analysis of Randomized Controlled Trials
Efficacy and Safety of Subcutaneous Immunotherapy for Local Allergic Rhinitis: A Meta-Analysis of Randomized Controlled Trials
BackgroundSubcutaneous immunotherapy (SCIT) has been used for treating local allergic rhinitis (LAR) patients. However, th...
Chronic rhinosinusitis with nasal polyposis (CRSwNP): the correlation between expression of Galectin-10 and Clinical-Cytological Grading (CCG)
Chronic rhinosinusitis with nasal polyposis (CRSwNP): the correlation between expression of Galectin-10 and Clinical-Cytological Grading (CCG)
BackgroundChronic rhinosinusitis with nasal polyps (CRSwNP) is typically characterized by Type 2 inflammation. Several bio...
Long-Term Outcomes of Nasoseptal Perforation Repair Using Anterior Maxillary Sinus Wall as an Interpositional Graft
Long-Term Outcomes of Nasoseptal Perforation Repair Using Anterior Maxillary Sinus Wall as an Interpositional Graft
BackgroundVarious graft materials have been used to repair nasoseptal perforation, but there is no standardized treatment ...
Complications Associated With Nasopharyngeal COVID-19 Testing: An Analysis of the MAUDE Database and Literature Review
Complications Associated With Nasopharyngeal COVID-19 Testing: An Analysis of the MAUDE Database and Literature Review
BackgroundNasopharyngeal swab testing, which has greatly increased in utilization due to the COVID-19 pandemic, is general...
Effect of Medical Therapy in Allergic Rhinitis: A Systematic Review and Meta-Analysis
Effect of Medical Therapy in Allergic Rhinitis: A Systematic Review and Meta-Analysis
BackgroundIntranasal corticosteroids (INCS), oral antihistamines (POAH), and allergen-specific immunotherapy (ASIT) are wi...
Effect of Silver Nitrate Application on the Success of Endoscopic Dacryocystorhinostomy
Effect of Silver Nitrate Application on the Success of Endoscopic Dacryocystorhinostomy
ObjectivesTo compare the clinical outcomes of patients undergoing additional procedures in endoscopic endonasal dacryocyst...
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