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Gut microbiota mediated the effects of high relative humidity on lupus in female MRL/lpr mice
Gut microbiota mediated the effects of high relative humidity on lupus in female MRL/lpr mice
The relationship between humidity and systemic lupus erythematosus (SLE) has yielded inconsistent results in prior researc...
A brazilian nationwide multicenter study on deficiency of deaminase-2 (DADA2)
A brazilian nationwide multicenter study on deficiency of deaminase-2 (DADA2)
The deficiency of ADA2 (DADA2) is a rare autoinflammatory disease provoked by mutations in the ADA2 gene inherited in a re...
Anti-SSA/SSB-negative primary Sjögren’s syndrome showing different clinical phenotypes: a retrospective study of 934 cases
Anti-SSA/SSB-negative primary Sjögren’s syndrome showing different clinical phenotypes: a retrospective study of 934 cases
Currently, only a few studies have described the general characteristics of patients with primary Sjögren’s syn...
Crosstalk between the JAK2 and TGF-β1 signaling pathways in scleroderma-related interstitial lung disease targeted by baricitinib
Crosstalk between the JAK2 and TGF-β1 signaling pathways in scleroderma-related interstitial lung disease targeted by baricitinib
Systemic sclerosis (SSc) is an immune-mediated rheumatic disease characterized by fibrosis and vascular lesions. Interstit...
Comparison of clinical features, disease activity, treatment and outcomes between late-onset and early-onset patients with systemic lupus erythematosus. A sex- and year at diagnosis-matched controlled study
Comparison of clinical features, disease activity, treatment and outcomes between late-onset and early-onset patients with systemic lupus erythematosus. A sex- and year at diagnosis-matched controlled study
Several studies have compared the clinical features and outcomes of late- and early-onset systemic lupus erythematosus (SL...
Microparticles: potential new contributors to the pathogenesis of systemic sclerosis?
Microparticles: potential new contributors to the pathogenesis of systemic sclerosis?
Microparticles (MPs) are membrane-derived vesicles released from cells undergoing activation or apoptosis with diverse pro...
Cognitive dysfunction in patients with childhood-onset systemic lupus erythematosus may impact treatment
Cognitive dysfunction in patients with childhood-onset systemic lupus erythematosus may impact treatment
Cognitive dysfunction (CD) is a widespread manifestation in adult systemic lupus erythematosus (SLE) patients, but this su...
Do it fast! Early access to specialized care improved long-term outcomes in rheumatoid arthritis: data from the REAL multicenter observational study
Do it fast! Early access to specialized care improved long-term outcomes in rheumatoid arthritis: data from the REAL multicenter observational study
Early rheumatoid arthritis (RA) offers an opportunity for better treatment outcomes. In real-life settings, grasping this ...
HLA-B27 positivity in a large miscegenated population of 5,389,143 healthy blood marrow donors in Brazil
HLA-B27 positivity in a large miscegenated population of 5,389,143 healthy blood marrow donors in Brazil
The prevalence of HLA-B27 gene positivity in healthy Caucasian communities varies between 8 and 14%. However, there is a l...
The role of proteasome in muscle wasting of experimental arthritis
The role of proteasome in muscle wasting of experimental arthritis
Rheumatoid arthritis is an autoimmune inflammatory disease that often leads patients to muscle impairment and physical dis...
Effectiveness and safety of secukinumab in ankylosing spondylitis and psoriatic arthritis: a 52-week real-life study in an Italian cohort
Effectiveness and safety of secukinumab in ankylosing spondylitis and psoriatic arthritis: a 52-week real-life study in an Italian cohort
Secukinumab has shown high efficacy in randomized controlled trials in both ankylosing spondylitis (AS) and psoriatic arth...
Prevalence of Sjögren's syndrome according to 2016 ACR-EULAR classification criteria in patients with systemic lupus erythematosus
Prevalence of Sjögren's syndrome according to 2016 ACR-EULAR classification criteria in patients with systemic lupus erythematosus
Diagnosis of SS is a complex task, as no symptom or test is unique to this syndrome. The American-European Consensus Group...
Comparative study of the synovial levels of RANKL and OPG in rheumatoid arthritis, spondyloarthritis and osteoarthritis
Comparative study of the synovial levels of RANKL and OPG in rheumatoid arthritis, spondyloarthritis and osteoarthritis
In chronic arthropathies, there are several mechanisms of joint destruction. In recent years, studies have reported the im...
Testing relationship between tea intake and the risk of rheumatoid arthritis and systemic lupus erythematosus: a Mendelian randomization study
Testing relationship between tea intake and the risk of rheumatoid arthritis and systemic lupus erythematosus: a Mendelian randomization study
We performed Mendelian randomization (MR) to assess the causal effect of tea intake on rheumatoid arthritis (RA) and syste...
Brazilian society of rheumatology methodological guide for the development of evidence-based clinical guidelines in rheumatology
Brazilian society of rheumatology methodological guide for the development of evidence-based clinical guidelines in rheumatology
Clinical practice guidelines (CPG) are developed to align standards of health care around the world, aiming to reduce the ...
Screening crucial lncRNAs and genes in osteoarthritis by integrated analysis
Screening crucial lncRNAs and genes in osteoarthritis by integrated analysis
Osteoarthritis (OA) is one of the most frequent chronic diseases with high morbidity worldwide, marked by degradation of t...
Blood levels of brain-derived neurotrophic factor (BDNF) in systemic lupus erythematous (SLE): a systematic review and meta-analysis
Blood levels of brain-derived neurotrophic factor (BDNF) in systemic lupus erythematous (SLE): a systematic review and meta-analysis
BDNF has been implicated in the pathophysiology of systemic lupus erythematosus (SLE), especially its neuropsychiatric sym...
SIRT1 is transcriptionally repressed by YY1 and suppresses ferroptosis in rheumatoid arthritis
SIRT1 is transcriptionally repressed by YY1 and suppresses ferroptosis in rheumatoid arthritis
Sirtuin 1 (SIRT1) is reported downregulated in rheumatoid arthritis (RA), and the protective effects of SIRT1 on tissue da...
Accuracy of Doppler ultrasound in the diagnosis of giant cell arteritis: a systematic review and meta-analysis
Accuracy of Doppler ultrasound in the diagnosis of giant cell arteritis: a systematic review and meta-analysis
Giant cell arteritis (GCA) is the most common primary systemic vasculitis in people 50 years of age and over, and...
Does the use of panoramic radiography add information in the temporomandibular joint evaluation in Juvenile Idiopathic Arthritis patients? A case control study
Does the use of panoramic radiography add information in the temporomandibular joint evaluation in Juvenile Idiopathic Arthritis patients? A case control study
To determine the frequency of radiographic changes in the temporomandibular joint, in a representative population of patie...
Correction to: Morphofunctional analysis of fibroblast-like synoviocytes in human rheumatoid arthritis and mouse collagen-induced arthritis
Correction to: Morphofunctional analysis of fibroblast-like synoviocytes in human rheumatoid arthritis and mouse collagen-induced arthritis
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whic...
Decreasing delays in the diagnosis and treatment of rheumatoid arthritis in Brazil: a nationwide multicenter observational study
Decreasing delays in the diagnosis and treatment of rheumatoid arthritis in Brazil: a nationwide multicenter observational study
Management delays imply worse outcomes in rheumatoid arthritis (RA) and, therefore, should be minimized. We evaluated chan...
Brazilian Portuguese version and content validity of the Strengthening and Stretching for Rheumatoid Arthritis of the Hand (SARAH)
Brazilian Portuguese version and content validity of the Strengthening and Stretching for Rheumatoid Arthritis of the Hand (SARAH)
The Strengthening and Stretching for Rheumatoid Arthritis of the Hand (SARAH) program is a personalized, progressive 12-we...
Morphofunctional analysis of fibroblast-like synoviocytes in human rheumatoid arthritis and mouse collagen-induced arthritis
Morphofunctional analysis of fibroblast-like synoviocytes in human rheumatoid arthritis and mouse collagen-induced arthritis
Fibroblast-like synoviocytes (FLS) play a prominent role in rheumatoid synovitis and degradation of the extracellular matr...
The impact of normal serum complement levels on the disease classification and clinical characteristics in systemic lupus erythematosus
The impact of normal serum complement levels on the disease classification and clinical characteristics in systemic lupus erythematosus
Some patients have normal levels of complement during the diagnosis of systemic lupus erythematosus (SLE), although decrea...
CD19+CD24highCD27+ B cell and interleukin 35 as potential biomarkers of disease activity in systemic lupus erythematosus patients
CD19+CD24highCD27+ B cell and interleukin 35 as potential biomarkers of disease activity in systemic lupus erythematosus patients
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that associates with aberrant activation of B lymphocy...
Immunomodulatory effects of atorvastatin on MRL/lpr mice
Immunomodulatory effects of atorvastatin on MRL/lpr mice
Statins have long been extensively prescribed as effective lipid-lowering agents, but statins have also been recognized as...
COVID-19 was not associated or trigger disease activity in spondylarthritis patients: ReumaCoV-Brasil cross-sectional data
COVID-19 was not associated or trigger disease activity in spondylarthritis patients: ReumaCoV-Brasil cross-sectional data
To evaluate the disease activity before and after COVID-19 and risk factors associated with outcomes, including hospitaliz...
Cross-cultural and clinical validation of the MDHAQ/RAPID3 questionnaire in electronic format for a Brazilian population of patients with rheumatoid arthritis
Cross-cultural and clinical validation of the MDHAQ/RAPID3 questionnaire in electronic format for a Brazilian population of patients with rheumatoid arthritis
Patients with rheumatologic diseases are monitored fundamentally through metric tools or index calculated from clinical da...
Treatment with biological therapy is associated with faster recovery and lower frequency of treatment switch among rheumatic patients with Chikungunya fever
Treatment with biological therapy is associated with faster recovery and lower frequency of treatment switch among rheumatic patients with Chikungunya fever
The effects of Chikungunya virus (CHIKV) infection on patients with rheumatic diseases have not been extensively studied. ...
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