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Circ_0026134 promotes NSCLC progression by the miR‐3619‐5p/CHAF1B axis
Circ_0026134 promotes NSCLC progression by the miR‐3619‐5p/CHAF1B axis
Abstract Background Non-small cell lung cancer (NSCLC) is the leading cause of cancer death worldwide. Circular RNAs (circ...
Clinical outcome, long‐term survival and tolerability of sequential therapy of first‐line crizotinib followed by alectinib in advanced ALK+NSCLC: A multicenter retrospective analysis in China
Clinical outcome, long‐term survival and tolerability of sequential therapy of first‐line crizotinib followed by alectinib in advanced ALK+NSCLC: A multicenter retrospective analysis in China
Abstract Background There is limited data on the clinical outcome, long-term survival and tolerability of sequential thera...
Optimal duration of adjuvant bisphosphonate treatment for high‐risk early breast cancer: Results from a SUCCESS trial
Optimal duration of adjuvant bisphosphonate treatment for high‐risk early breast cancer: Results from a SUCCESS trial
GLOBOCAN 2020 estimates that breast cancer is the most common cancer in the world, with an age standardized incidence rate...
Left sleeve pneumonectomy via uniportal video‐assisted thoracoscopic approach
Left sleeve pneumonectomy via uniportal video‐assisted thoracoscopic approach
Abstract Left sleeve pneumonectomy is a rarer intervention compared with right sleeve pneumonectomy. It is a challenging s...
Efficacy and safety of WBRT+EGFR‐TKI versus WBRT only in the treatment of NSCLC patients with brain metastasis: An updated meta‐analysis
Efficacy and safety of WBRT+EGFR‐TKI versus WBRT only in the treatment of NSCLC patients with brain metastasis: An updated meta‐analysis
Abstract Background To investigate the efficacy and safety of whole brain radiotherapy (WBRT) combined with epidermal grow...
Clinical characteristics and prognostic model for extensive‐stage small cell lung cancer: A retrospective study over an 8‐year period
Clinical characteristics and prognostic model for extensive‐stage small cell lung cancer: A retrospective study over an 8‐year period
Abstract Background Small cell lung cancer (SCLC) is a highly aggressive neuroendocrine tumor with a short replication tim...
Rarest of rare cases within the one thousand faces of atypical carcinoid: Pseudomesotheliomatous manifestation in a pregnant woman
Rarest of rare cases within the one thousand faces of atypical carcinoid: Pseudomesotheliomatous manifestation in a pregnant woman
Abstract Carcinoid tumors in pregnant women are rare, and there have been no previous studies of atypical carcinoid tumor ...
Short‐term safety of an anti‐severe acute respiratory syndrome coronavirus 2 messenger RNA vaccine for patients with advanced lung cancer treated with anticancer drugs: A multicenter, prospective, observational study
Short‐term safety of an anti‐severe acute respiratory syndrome coronavirus 2 messenger RNA vaccine for patients with advanced lung cancer treated with anticancer drugs: A multicenter, prospective, observational study
Abstract Background Since 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become prevalent worldwid...
Effectiveness of alectinib and osimertinib in a brain metastasized lung adenocarcinoma patient with concurrent EGFR mutations and DCTN1‐ALK fusion
Effectiveness of alectinib and osimertinib in a brain metastasized lung adenocarcinoma patient with concurrent EGFR mutations and DCTN1‐ALK fusion
Abstract The echinoderm microtubule associated protein-like 4 gene (EML4) encodes the predominant anaplastic lymphoma kina...
Impact of sarcopenia on chemotherapy‐triggered exacerbation of interstitial lung disease in patients with non‐small cell lung cancer
Impact of sarcopenia on chemotherapy‐triggered exacerbation of interstitial lung disease in patients with non‐small cell lung cancer
Abstract Background While recent evidence has suggested that sarcopenia could predict chemotoxicity, its association with ...
Combined targeting of EGFR and BRAF triggers regression of osimertinib resistance by using osimertinib and vemurafenib concurrently in a patient with heterogeneity between different lesions
Combined targeting of EGFR and BRAF triggers regression of osimertinib resistance by using osimertinib and vemurafenib concurrently in a patient with heterogeneity between different lesions
Abstract Acquired BRAF V600E mutation can occur in tumors with EGFR mutation and is suspected as a resistance mechanism to...
Low baseline plasma PCSK9 level is associated with good clinical outcomes of immune checkpoint inhibitors in advanced non‐small cell lung cancer
Low baseline plasma PCSK9 level is associated with good clinical outcomes of immune checkpoint inhibitors in advanced non‐small cell lung cancer
Abstract Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a crucial protein involved in the metabolism ...
Use of PD‐1 inhibitor tislelizumab in the treatment of advanced pulmonary sarcomatoid carcinoma: A case report
Use of PD‐1 inhibitor tislelizumab in the treatment of advanced pulmonary sarcomatoid carcinoma: A case report
Abstract Pulmonary sarcomatoid carcinoma (PSC), characterized by poor differentiation, aggressive progression, and early m...
miR‐223‐3p targets FBXW7 to promote epithelial‐mesenchymal transition and metastasis in breast cancer
miR‐223‐3p targets FBXW7 to promote epithelial‐mesenchymal transition and metastasis in breast cancer
Abstract Background Breast cancer is the most common malignant tumor diagnosed in women. It is the second leading cause of...
Association of the programmed death ligand‐1 combined positive score in tumors and clinicopathological features in esophageal cancer
Association of the programmed death ligand‐1 combined positive score in tumors and clinicopathological features in esophageal cancer
Abstract Background The combined positive score (CPS) of the programmed death ligand-1 (PD-L1) 22C3 assay is a predictive ...
MiR‐192/NKRF axis confers lung cancer cell chemoresistance to cisplatin via the NF‐κB pathway
MiR‐192/NKRF axis confers lung cancer cell chemoresistance to cisplatin via the NF‐κB pathway
Abstract Background Chemoresistance influences the therapeutic effect of cisplatin and remains a major obstacle to its cli...
Immunotherapy plus chemotherapy showed superior clinical benefit to chemotherapy alone in advanced NSCLC patients after progression on osimertinib
Immunotherapy plus chemotherapy showed superior clinical benefit to chemotherapy alone in advanced NSCLC patients after progression on osimertinib
Abstract Background Osimertinib is the standard first-line treatment for non-small cell lung cancer (NSCLC) patients with ...
Preoperative electromagnetic navigation bronchoscopy‐guided one‐stage multiple‐dye localization for resection of subsolid nodules: A single‐center pilot study
Preoperative electromagnetic navigation bronchoscopy‐guided one‐stage multiple‐dye localization for resection of subsolid nodules: A single‐center pilot study
Abstract Background Electromagnetic navigation bronchoscopy (ENB)-guided transbronchial dye marking and video-assisted tho...
High GNG4 expression is associated with poor prognosis in patients with lung adenocarcinoma
High GNG4 expression is associated with poor prognosis in patients with lung adenocarcinoma
Abstract Background The purpose of this study was to explore the reason for guanine nucleotide binding-protein gamma subun...
Colorectal cancer‐related pulmonary metastasectomy: Factors affecting survival time
Colorectal cancer‐related pulmonary metastasectomy: Factors affecting survival time
We congratulate Dr Yang and colleagues for an important analysis investigating the utility of adding mediastinal lymph nod...
Host immune‐inflammatory markers to unravel the heterogeneous outcome and assessment of patients with PD‐L1 ≥50% metastatic non‐small cell lung cancer and poor performance status receiving first‐line immunotherapy
Host immune‐inflammatory markers to unravel the heterogeneous outcome and assessment of patients with PD‐L1 ≥50% metastatic non‐small cell lung cancer and poor performance status receiving first‐line immunotherapy
Abstract Background Patients with programmed cell death-ligand 1 (PD-L1) ≥50% metastatic non-small cell lung cancer...
Immune checkpoint inhibitor‐related adverse events in lung cancer: Real‐world incidence and management practices of 1905 patients in China
Immune checkpoint inhibitor‐related adverse events in lung cancer: Real‐world incidence and management practices of 1905 patients in China
Abstract Background Immune checkpoint inhibitors (ICIs) are the standard treatment for advanced lung cancer, but immune-re...
Uniportal video‐assisted thoracic surgery approach for simultaneous lung cancer and thymic carcinoma: Case report and literature review
Uniportal video‐assisted thoracic surgery approach for simultaneous lung cancer and thymic carcinoma: Case report and literature review
Abstract Thymic carcinoma is an epithelial tumor derived from thymic epithelial cells. Thymic tumors may be associated wit...
ASCL1 and DLL3 expressions and their clinicopathological implications in surgically resected pure small cell lung cancer: A study of 247 cases from the National Cancer Center of China
ASCL1 and DLL3 expressions and their clinicopathological implications in surgically resected pure small cell lung cancer: A study of 247 cases from the National Cancer Center of China
Abstract Objective Small cell lung cancer (SCLC) is one of the most aggressive malignancies characterized by neuroendocrin...
Does size affect the prognosis of resectable thymoma beyond the eighth edition TNM?
Does size affect the prognosis of resectable thymoma beyond the eighth edition TNM?
Abstract Background Thymoma is a type of rare mediastinal tumor whose clinical characteristics and indicators of prognosis...
Dramatic response to immunochemotherapy followed by salvage surgery in an elderly lung cancer patient
Dramatic response to immunochemotherapy followed by salvage surgery in an elderly lung cancer patient
Abstract Immune checkpoint inhibitors (ICIs) have caused a paradigm shift in the treatment of lung cancer. Here, we encoun...
Differential diagnosis of lung cancer and benign lung lesion using salivary metabolites: A preliminary study
Differential diagnosis of lung cancer and benign lung lesion using salivary metabolites: A preliminary study
Abstract Background Saliva is often used as a biomarker for the diagnosis of some oral and systematic diseases, owing to t...
Successful erlotinib rechallenge in an EGFR‐mutant metastatic non‐small cell lung cancer patient with afatinib‐induced drug rash with eosinophilia and systemic symptoms: A case report
Successful erlotinib rechallenge in an EGFR‐mutant metastatic non‐small cell lung cancer patient with afatinib‐induced drug rash with eosinophilia and systemic symptoms: A case report
Abstract Tyrosine kinase inhibitors (TKIs) are the standard treatment for epidermal growth factor receptor (EGFR)-mutant a...
Development and validation of a prediction model using molecular marker for long‐term survival in unresectable stage III non‐small cell lung cancer treated with chemoradiotherapy
Development and validation of a prediction model using molecular marker for long‐term survival in unresectable stage III non‐small cell lung cancer treated with chemoradiotherapy
Abstract Background This study aimed to establish a predictive nomogram integrating epidermal growth factor receptor (EGFR...
“Split” combined subsegmentectomy: A case series
“Split” combined subsegmentectomy: A case series
Abstract Background Clinically, some specific pulmonary nodules have safe resection margins that are located in multiple s...
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