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Carvone-loaded chitosan nanoparticles alleviate joint destruction by downregulating the expression of pro, inflammatory cytokines and MMP-13 in adjuvant-induced rat model
Carvone-loaded chitosan nanoparticles alleviate joint destruction by downregulating the expression of pro, inflammatory cytokines and MMP-13 in adjuvant-induced rat model
Rheumatoid arthritis is an autoimmune illness causing deformity, edema, and joint tenderness. Its long-term treatment burd...
Examining the role of antioxidant supplementation in mitigating oxidative stress markers in Alzheimer’s disease: a comprehensive review
Examining the role of antioxidant supplementation in mitigating oxidative stress markers in Alzheimer’s disease: a comprehensive review
Alzheimer’s disease is a devastating neurodegenerative disorder that affects millions of people worldwide. One of th...
Anti-inflammatory effect of nestorone in a lipopolysaccharide-induced acute lung injury model through regulation of the TLR-4/Myd88/NF-κB signaling pathway
Anti-inflammatory effect of nestorone in a lipopolysaccharide-induced acute lung injury model through regulation of the TLR-4/Myd88/NF-κB signaling pathway
Progesterone plays a crucial and indispensable role in regulating immunity and attenuating inflammation. Nestorone® (...
Effects of tranexamic acid on postoperative knee activity and stress, and inflammation cytokines in patients undergoing total knee arthroplasty
Effects of tranexamic acid on postoperative knee activity and stress, and inflammation cytokines in patients undergoing total knee arthroplasty
Total knee arthroplasty (TKA) is an effective treatment for knee osteoarthritis, with postoperative bleeding and the infla...
Mechanisms of action of ethyl acetate fractions of Liparis nervosa (Thunb.) Lindl. as potential central anti-nociceptive agents
Mechanisms of action of ethyl acetate fractions of Liparis nervosa (Thunb.) Lindl. as potential central anti-nociceptive agents
Opioids/non-steroidal anti-inflammatory drugs are used to alleviate pain; however, they are expensive and can have adverse...
Epidural injection of varying doses of capsaicin alleviates inflammatory pain in rats via the TLR4/AKT/NF-κB pathway
Epidural injection of varying doses of capsaicin alleviates inflammatory pain in rats via the TLR4/AKT/NF-κB pathway
Capsaicin (CAP) induces transient pain sensation by activating transient receptor potential vanilloid-1 (TRPV1). However, ...
Prooxidant state in anticancer drugs and prospect use of mitochondrial cofactors and anti-inflammatory agents in cancer prevention
Prooxidant state in anticancer drugs and prospect use of mitochondrial cofactors and anti-inflammatory agents in cancer prevention
An extensive body of literature has associated cancer with redox imbalance and inflammatory conditions. Thus, several stud...
Pharmaceutical aspects of JAK inhibitors: a comparative review
Pharmaceutical aspects of JAK inhibitors: a comparative review
Janus kinase inhibitors (JAKIs) are a new class of drugs used in the treatment of a heterogeneous group of diseases, mainl...
Vitexin mitigates oxidative stress, mitochondrial damage, pyroptosis and regulates small nucleolar RNA host gene 1/DNA methyltransferase 1/microRNA-495 axis in sepsis-associated acute lung injury
Vitexin mitigates oxidative stress, mitochondrial damage, pyroptosis and regulates small nucleolar RNA host gene 1/DNA methyltransferase 1/microRNA-495 axis in sepsis-associated acute lung injury
This study examined vitexin’s effect on sepsis-induced acute lung injury. We used network pharmacology and ...
β-Citronellol: a potential anti-inflammatory and gastro-protective agent-mechanistic insights into its modulatory effects on COX-II, 5-LOX, eNOS, and ICAM-1 pathways through in vitro, in vivo, in silico, and network pharmacology studies
β-Citronellol: a potential anti-inflammatory and gastro-protective agent-mechanistic insights into its modulatory effects on COX-II, 5-LOX, eNOS, and ICAM-1 pathways through in vitro, in vivo, in silico, and network pharmacology studies
The current study aimed to evaluate the anti-inflammatory, anti-oxidant, and pronounced gastro-protective activities of &#...
Zhumeria majdae essential oil attenuates TNBS-induced colitis in rats by regulating inflammatory and apoptotic pathways
Zhumeria majdae essential oil attenuates TNBS-induced colitis in rats by regulating inflammatory and apoptotic pathways
Zhumeria majdae, a unique native plant of southern Iran, has been traditionally used to treat various health issues. Precl...
The role of traditional NSAIDs and selective COX-2 inhibitors on COVID-19 outcomes: a real-world data study
The role of traditional NSAIDs and selective COX-2 inhibitors on COVID-19 outcomes: a real-world data study
The relation between use of nonsteroidal anti-inflammatory drugs (NSAIDs) and severity of COVID-19 has been the subject to...
Repurposing celecoxib as adjuvant therapy in patients with Parkinsonian disease: a new therapeutic dawn: randomized controlled pilot study
Repurposing celecoxib as adjuvant therapy in patients with Parkinsonian disease: a new therapeutic dawn: randomized controlled pilot study
The clinical presentations of Parkinson’s disease (PD), a chronic neurodegenerative condition, include bradykinesia,...
Combinatorial intervention with dental pulp stem cells and sulfasalazine in a rat model of ulcerative colitis
Combinatorial intervention with dental pulp stem cells and sulfasalazine in a rat model of ulcerative colitis
Ulcerative colitis is an inflammatory bowel disease (IBD) that involves inflammation of the colon lining and rectum. Altho...
Essential oils: a potential alternative with promising active ingredients for pharmaceutical formulations in chronic wound management
Essential oils: a potential alternative with promising active ingredients for pharmaceutical formulations in chronic wound management
Chronic wound is a major clinical challenge that complicates wound healing, mainly associated with bacterial biofilms. Bac...
Anti-arthritic studies of ethnomedicine Gaultheria trichophylla Royle extract and salicylate-rich fraction using complete Freud’s adjuvant-induced rats: molecular docking and network pharmacology analysis
Anti-arthritic studies of ethnomedicine Gaultheria trichophylla Royle extract and salicylate-rich fraction using complete Freud’s adjuvant-induced rats: molecular docking and network pharmacology analysis
Gaultheria trichophylla Royle is a traditional treatment for inflammatory conditions including arthritis. The objective wa...
Correction to: Anti-arthritic and immunomodulatory efficacy of Micromeria biflora Benth extract and its fractions in rats by restoring oxidative stress, metalloproteinases, pro-inflammatory and anti-inflammatory cytokines network
Correction to: Anti-arthritic and immunomodulatory efficacy of Micromeria biflora Benth extract and its fractions in rats by restoring oxidative stress, metalloproteinases, pro-inflammatory and anti-inflammatory cytokines network
Cite this articleAl-Joufi, F.A., Uttra, A.M., Qasim, S. et al. Correction to: Anti-arthritic and immunomodulatory efficacy...
Unveiling the antimicrobial, antivirulence, and wound-healing accelerating potentials of resveratrol against carbapenem-resistant Pseudomonas aeruginosa (CRPA)-septic wound in a murine model
Unveiling the antimicrobial, antivirulence, and wound-healing accelerating potentials of resveratrol against carbapenem-resistant Pseudomonas aeruginosa (CRPA)-septic wound in a murine model
Pseudomonas aeruginosa is a repertoire of several virulence factors that create a frightening high pathogenicity level as ...
Therapeutic applications of eucalyptus essential oils
Therapeutic applications of eucalyptus essential oils
Eucalyptus essential oils (EEOs) have gained significant attention recently anticipated to their broad range of prospectiv...
From metabolomics to therapeutics: identifying causal metabolites and potential drugs for the treatment of osteoarthritis
From metabolomics to therapeutics: identifying causal metabolites and potential drugs for the treatment of osteoarthritis
Osteoarthritis (OA) is a common age-related disease that causes pain and impaired mobility. Various blood metabolites are ...
Therapeutic potential of plant polyphenols in acute pancreatitis
Therapeutic potential of plant polyphenols in acute pancreatitis
Acute pancreatitis is a potentially life-threatening inflammatory disorder of the exocrine pancreas characterized by early...
Targeting high-mobility-group-box-1-mediated inflammation: a promising therapeutic approach for myocardial infarction
Targeting high-mobility-group-box-1-mediated inflammation: a promising therapeutic approach for myocardial infarction
Myocardial ischemia, resulting from coronary artery blockage, precipitates cardiac arrhythmias, myocardial structural chan...
Gut microbiome and inflammation in cardiovascular drug response: trends in therapeutic success and commercial focus
Gut microbiome and inflammation in cardiovascular drug response: trends in therapeutic success and commercial focus
The intricate Gut microbiome is evolving as an important system and is hypothesized to be a “metabolic organ” ...
Thiostrepton: multifaceted biological activities and its applications in treatment of inflammatory diseases
Thiostrepton: multifaceted biological activities and its applications in treatment of inflammatory diseases
Thiostrepton (TST) is a naturally occurring oligopeptide antibiotic with a demonstrated capacity to antagonize a broad spe...
Unlocking the therapeutic potential of Geraniol: an alternative perspective for metabolic disease management
Unlocking the therapeutic potential of Geraniol: an alternative perspective for metabolic disease management
Natural substance geraniol has anti-inflammatory and antioxidant qualities. It may be used to treat metabolic diseases suc...
Cyclosporin for the treatment of Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN): a systematic review of observational studies and clinical trials focusing on single therapy, combination therapy, and comparative assessments
Cyclosporin for the treatment of Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN): a systematic review of observational studies and clinical trials focusing on single therapy, combination therapy, and comparative assessments
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, severe, and potentially life-threateni...
Anti-inflammatory effects of a methanol extract from Montanoa grandiflora DC. (Asteraceae) leaves on in vitro and in vivo models
Anti-inflammatory effects of a methanol extract from Montanoa grandiflora DC. (Asteraceae) leaves on in vitro and in vivo models
Montanoa grandiflora, a plant species native from Mexico to Central America, locally known as “Teresita” in Yu...
Identification of JAZF1, KNOP1, and PLEKHA1 as causally associated genes and drug targets for Alzheimer’s disease: a summary data-based Mendelian randomization study
Identification of JAZF1, KNOP1, and PLEKHA1 as causally associated genes and drug targets for Alzheimer’s disease: a summary data-based Mendelian randomization study
There is a growing body of evidence indicating the significant role of the immune system and immune cells in the progressi...
Exploring the role of HIF-1α on pathogenesis in Alzheimer’s disease and potential therapeutic approaches
Exploring the role of HIF-1α on pathogenesis in Alzheimer’s disease and potential therapeutic approaches
Hypoxia-inducible factor 1α (HIF-1α) is a crucial transcription factor that regulates cellular responses to low ...
Hydrogel encapsulating gold nanoparticles for targeted delivery of nitroglycerin to reduce post-cardiac dysfunction inflammation by inhibiting the Wnt/β-catenin signaling pathway
Hydrogel encapsulating gold nanoparticles for targeted delivery of nitroglycerin to reduce post-cardiac dysfunction inflammation by inhibiting the Wnt/β-catenin signaling pathway
The discovery of nitric oxide's role in biological processes like platelet function, vasodilation, cell permeability, ...
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