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β-Citronellol: a potential anti-inflammatory and gastro-protective agent-mechanistic insights into its modulatory effects on COX-II, 5-LOX, eNOS, and ICAM-1 pathways through in vitro, in vivo, in silico, and network pharmacology studies
β-Citronellol: a potential anti-inflammatory and gastro-protective agent-mechanistic insights into its modulatory effects on COX-II, 5-LOX, eNOS, and ICAM-1 pathways through in vitro, in vivo, in silico, and network pharmacology studies
The current study aimed to evaluate the anti-inflammatory, anti-oxidant, and pronounced gastro-protective activities of &#...
Zhumeria majdae essential oil attenuates TNBS-induced colitis in rats by regulating inflammatory and apoptotic pathways
Zhumeria majdae essential oil attenuates TNBS-induced colitis in rats by regulating inflammatory and apoptotic pathways
Zhumeria majdae, a unique native plant of southern Iran, has been traditionally used to treat various health issues. Precl...
The role of traditional NSAIDs and selective COX-2 inhibitors on COVID-19 outcomes: a real-world data study
The role of traditional NSAIDs and selective COX-2 inhibitors on COVID-19 outcomes: a real-world data study
The relation between use of nonsteroidal anti-inflammatory drugs (NSAIDs) and severity of COVID-19 has been the subject to...
Repurposing celecoxib as adjuvant therapy in patients with Parkinsonian disease: a new therapeutic dawn: randomized controlled pilot study
Repurposing celecoxib as adjuvant therapy in patients with Parkinsonian disease: a new therapeutic dawn: randomized controlled pilot study
The clinical presentations of Parkinson’s disease (PD), a chronic neurodegenerative condition, include bradykinesia,...
Combinatorial intervention with dental pulp stem cells and sulfasalazine in a rat model of ulcerative colitis
Combinatorial intervention with dental pulp stem cells and sulfasalazine in a rat model of ulcerative colitis
Ulcerative colitis is an inflammatory bowel disease (IBD) that involves inflammation of the colon lining and rectum. Altho...
Essential oils: a potential alternative with promising active ingredients for pharmaceutical formulations in chronic wound management
Essential oils: a potential alternative with promising active ingredients for pharmaceutical formulations in chronic wound management
Chronic wound is a major clinical challenge that complicates wound healing, mainly associated with bacterial biofilms. Bac...
Anti-arthritic studies of ethnomedicine Gaultheria trichophylla Royle extract and salicylate-rich fraction using complete Freud’s adjuvant-induced rats: molecular docking and network pharmacology analysis
Anti-arthritic studies of ethnomedicine Gaultheria trichophylla Royle extract and salicylate-rich fraction using complete Freud’s adjuvant-induced rats: molecular docking and network pharmacology analysis
Gaultheria trichophylla Royle is a traditional treatment for inflammatory conditions including arthritis. The objective wa...
Correction to: Anti-arthritic and immunomodulatory efficacy of Micromeria biflora Benth extract and its fractions in rats by restoring oxidative stress, metalloproteinases, pro-inflammatory and anti-inflammatory cytokines network
Correction to: Anti-arthritic and immunomodulatory efficacy of Micromeria biflora Benth extract and its fractions in rats by restoring oxidative stress, metalloproteinases, pro-inflammatory and anti-inflammatory cytokines network
Cite this articleAl-Joufi, F.A., Uttra, A.M., Qasim, S. et al. Correction to: Anti-arthritic and immunomodulatory efficacy...
Unveiling the antimicrobial, antivirulence, and wound-healing accelerating potentials of resveratrol against carbapenem-resistant Pseudomonas aeruginosa (CRPA)-septic wound in a murine model
Unveiling the antimicrobial, antivirulence, and wound-healing accelerating potentials of resveratrol against carbapenem-resistant Pseudomonas aeruginosa (CRPA)-septic wound in a murine model
Pseudomonas aeruginosa is a repertoire of several virulence factors that create a frightening high pathogenicity level as ...
Therapeutic applications of eucalyptus essential oils
Therapeutic applications of eucalyptus essential oils
Eucalyptus essential oils (EEOs) have gained significant attention recently anticipated to their broad range of prospectiv...
From metabolomics to therapeutics: identifying causal metabolites and potential drugs for the treatment of osteoarthritis
From metabolomics to therapeutics: identifying causal metabolites and potential drugs for the treatment of osteoarthritis
Osteoarthritis (OA) is a common age-related disease that causes pain and impaired mobility. Various blood metabolites are ...
Therapeutic potential of plant polyphenols in acute pancreatitis
Therapeutic potential of plant polyphenols in acute pancreatitis
Acute pancreatitis is a potentially life-threatening inflammatory disorder of the exocrine pancreas characterized by early...
Targeting high-mobility-group-box-1-mediated inflammation: a promising therapeutic approach for myocardial infarction
Targeting high-mobility-group-box-1-mediated inflammation: a promising therapeutic approach for myocardial infarction
Myocardial ischemia, resulting from coronary artery blockage, precipitates cardiac arrhythmias, myocardial structural chan...
Gut microbiome and inflammation in cardiovascular drug response: trends in therapeutic success and commercial focus
Gut microbiome and inflammation in cardiovascular drug response: trends in therapeutic success and commercial focus
The intricate Gut microbiome is evolving as an important system and is hypothesized to be a “metabolic organ” ...
Thiostrepton: multifaceted biological activities and its applications in treatment of inflammatory diseases
Thiostrepton: multifaceted biological activities and its applications in treatment of inflammatory diseases
Thiostrepton (TST) is a naturally occurring oligopeptide antibiotic with a demonstrated capacity to antagonize a broad spe...
Unlocking the therapeutic potential of Geraniol: an alternative perspective for metabolic disease management
Unlocking the therapeutic potential of Geraniol: an alternative perspective for metabolic disease management
Natural substance geraniol has anti-inflammatory and antioxidant qualities. It may be used to treat metabolic diseases suc...
Cyclosporin for the treatment of Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN): a systematic review of observational studies and clinical trials focusing on single therapy, combination therapy, and comparative assessments
Cyclosporin for the treatment of Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN): a systematic review of observational studies and clinical trials focusing on single therapy, combination therapy, and comparative assessments
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, severe, and potentially life-threateni...
Anti-inflammatory effects of a methanol extract from Montanoa grandiflora DC. (Asteraceae) leaves on in vitro and in vivo models
Anti-inflammatory effects of a methanol extract from Montanoa grandiflora DC. (Asteraceae) leaves on in vitro and in vivo models
Montanoa grandiflora, a plant species native from Mexico to Central America, locally known as “Teresita” in Yu...
Identification of JAZF1, KNOP1, and PLEKHA1 as causally associated genes and drug targets for Alzheimer’s disease: a summary data-based Mendelian randomization study
Identification of JAZF1, KNOP1, and PLEKHA1 as causally associated genes and drug targets for Alzheimer’s disease: a summary data-based Mendelian randomization study
There is a growing body of evidence indicating the significant role of the immune system and immune cells in the progressi...
Exploring the role of HIF-1α on pathogenesis in Alzheimer’s disease and potential therapeutic approaches
Exploring the role of HIF-1α on pathogenesis in Alzheimer’s disease and potential therapeutic approaches
Hypoxia-inducible factor 1α (HIF-1α) is a crucial transcription factor that regulates cellular responses to low ...
Hydrogel encapsulating gold nanoparticles for targeted delivery of nitroglycerin to reduce post-cardiac dysfunction inflammation by inhibiting the Wnt/β-catenin signaling pathway
Hydrogel encapsulating gold nanoparticles for targeted delivery of nitroglycerin to reduce post-cardiac dysfunction inflammation by inhibiting the Wnt/β-catenin signaling pathway
The discovery of nitric oxide's role in biological processes like platelet function, vasodilation, cell permeability, ...
Vitamin D: A key player in COVID-19 immunity and lessons from the pandemic to combat immune-evasive variants
Vitamin D: A key player in COVID-19 immunity and lessons from the pandemic to combat immune-evasive variants
As of the 7th of July 2024, 775,754,322 confirmed cases of COVID-19, including 7,053,902 deaths worldwide, had been report...
Efficacy and safety of 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1, 2-benzothiazin-3-carboxamide 1,1-dioxide, a rapid-acting meloxicam formulation, for analgesia after orthopaedic surgery under general anaesthesia: a randomized controlled trial
Efficacy and safety of 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1, 2-benzothiazin-3-carboxamide 1,1-dioxide, a rapid-acting meloxicam formulation, for analgesia after orthopaedic surgery under general anaesthesia: a randomized controlled trial
Postoperative pain management is one of the most challenging treatments after orthopaedic surgery, and improved medical tr...
Opuntia ficus-indica cladodes extract inhibits human neutrophil pro-inflammatory functions and protects rats from acetic acid-induced ulcerative colitis
Opuntia ficus-indica cladodes extract inhibits human neutrophil pro-inflammatory functions and protects rats from acetic acid-induced ulcerative colitis
The increased production of reactive oxygen species (ROS) by human neutrophils can lead to oxidative imbalances and severa...
On the origin of cysteamine-induced duodenal cytotoxicity and type II ferroptosis
On the origin of cysteamine-induced duodenal cytotoxicity and type II ferroptosis
Cysteamine (CA) induces duodenal ulcers in rodents (Selye and Szabo, Nature 244:458–459, 1973). Cysteine (Cys), a pr...
The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials
The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials
Vitamin D, known for its role in bone health, is now being explored for its immunomodulatory effects. This study aimed to ...
Conventional DMARDs therapy decreases disease activity and inflammation in newly diagnosed patients with rheumatoid arthritis by increasing FoxP3, Sema-3A, and Nrp-1 gene expression
Conventional DMARDs therapy decreases disease activity and inflammation in newly diagnosed patients with rheumatoid arthritis by increasing FoxP3, Sema-3A, and Nrp-1 gene expression
Semaphorins are axonal guidance molecules involved in neural development and contribute to the regulation of various phase...
Unlocking the potential of flavonoid-infused drug delivery systems for diabetic wound healing with a mechanistic exploration
Unlocking the potential of flavonoid-infused drug delivery systems for diabetic wound healing with a mechanistic exploration
Diabetes is one of the common endocrine disorders generally characterized by elevated levels of blood sugar. It can origin...
Janus kinase inhibitors versus tumor necrosis factor inhibitors in rheumatoid arthritis: meta-analytical comparison of efficacy and safety
Janus kinase inhibitors versus tumor necrosis factor inhibitors in rheumatoid arthritis: meta-analytical comparison of efficacy and safety
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disorder characterized by persistent inflammation leading to pr...
Gingerol nanoparticles attenuate complete Freund adjuvant-induced arthritis in rats via targeting the RANKL/OPG signaling pathway
Gingerol nanoparticles attenuate complete Freund adjuvant-induced arthritis in rats via targeting the RANKL/OPG signaling pathway
Rheumatoid arthritis (RA) is characterized by inflammatory joint pathology leading to the degradation of articular bone an...
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