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Deep learning classification of uveal melanoma based on histopathological images and identification of a novel indicator for prognosis of patients
Deep learning classification of uveal melanoma based on histopathological images and identification of a novel indicator for prognosis of patients
Deep learning has been extensively used in digital histopathology. The purpose of this study was to test deep learning (DL...
Correction: Isolation and characterization of apical papilla cells from root end of human third molar and their differentiation into cementoblast cells: an in vitro study
Correction: Isolation and characterization of apical papilla cells from root end of human third molar and their differentiation into cementoblast cells: an in vitro study
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
TACE responser NDRG1 acts as a guardian against ferroptosis to drive tumorgenesis and metastasis in HCC
TACE responser NDRG1 acts as a guardian against ferroptosis to drive tumorgenesis and metastasis in HCC
The treatment efficacy of transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) varies widely between ...
Correction: The role of three‑dimensional scaffolds based on polyglycerol sebacate/ polycaprolactone/ gelatin in the presence of Nanohydroxyapatite in promoting chondrogenic differentiation of human adipose‑derived mesenchymal stem cells
Correction: The role of three‑dimensional scaffolds based on polyglycerol sebacate/ polycaprolactone/ gelatin in the presence of Nanohydroxyapatite in promoting chondrogenic differentiation of human adipose‑derived mesenchymal stem cells
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
BPTF in bone marrow provides a potential progression biomarker regulated by TFAP4 through the PI3K/AKT pathway in neuroblastoma
BPTF in bone marrow provides a potential progression biomarker regulated by TFAP4 through the PI3K/AKT pathway in neuroblastoma
Neuroblastoma (NB) is the most common extracranial malignant solid tumor in children, which is highly prone to bone marrow...
Exosomal microRNA-342-5p secreted from adipose-derived mesenchymal stem cells mitigates acute kidney injury in sepsis mice by inhibiting TLR9
Exosomal microRNA-342-5p secreted from adipose-derived mesenchymal stem cells mitigates acute kidney injury in sepsis mice by inhibiting TLR9
Sepsis-related acute kidney injury (AKI) is an inflammatory disease associated with extremely high mortality and health bu...
The role of three-dimensional scaffolds based on polyglycerol sebacate/ polycaprolactone/ gelatin in the presence of Nanohydroxyapatite in promoting chondrogenic differentiation of human adipose-derived mesenchymal stem cells
The role of three-dimensional scaffolds based on polyglycerol sebacate/ polycaprolactone/ gelatin in the presence of Nanohydroxyapatite in promoting chondrogenic differentiation of human adipose-derived mesenchymal stem cells
Tissue engineering for cartilage regeneration has made great advances in recent years, although there are still challenges...
YTHDF2 exerts tumor-suppressor roles in gastric cancer via up-regulating PPP2CA independently of m6A modification
YTHDF2 exerts tumor-suppressor roles in gastric cancer via up-regulating PPP2CA independently of m6A modification
YTHDF2 is one of important readers of N6-methyladenosine (m6A) modification on RNA. Growing evidence implicates that YTHDF...
Blocking Abundant RNA Transcripts by High-Affinity Oligonucleotides during Transcriptome Library Preparation
Blocking Abundant RNA Transcripts by High-Affinity Oligonucleotides during Transcriptome Library Preparation
RNA sequencing has become the gold standard for transcriptome analysis but has an inherent limitation of challenging quant...
Macrophage-Derived MMP-9 and MMP-2 are Closely Related to the Rupture of the Fibrous Capsule of Hepatocellular Carcinoma Leading to Tumor Invasion
Macrophage-Derived MMP-9 and MMP-2 are Closely Related to the Rupture of the Fibrous Capsule of Hepatocellular Carcinoma Leading to Tumor Invasion
Hepatocellular carcinoma (HCC) is an aggressive tumor with a poor clinical prognosis. Rupture of the fibrous capsule (FC) ...
Influence of Exosomes on Astrocytes in the Pre-Metastatic Niche of Lung Cancer Brain Metastases
Influence of Exosomes on Astrocytes in the Pre-Metastatic Niche of Lung Cancer Brain Metastases
Lung cancer is the most common cause of cancer-related death globally. There are several reasons for this high mortality r...
A 3D human co-culture to model neuron-astrocyte interactions in tauopathies
A 3D human co-culture to model neuron-astrocyte interactions in tauopathies
Intraneuronal tau aggregation is the major pathological hallmark of neurodegenerative tauopathies. It is now generally ack...
Ultrasound and microbubble-mediated delivery of miR-424-5p has a therapeutic effect in preeclampsia
Ultrasound and microbubble-mediated delivery of miR-424-5p has a therapeutic effect in preeclampsia
To determine the influence of ultrasound/microbubble-mediated miR-424-5p delivery on trophoblast cells and the un...
Isolation and characterization of apical papilla cells from root end of human third molar and their differentiation into cementoblast cells: an in vitro study
Isolation and characterization of apical papilla cells from root end of human third molar and their differentiation into cementoblast cells: an in vitro study
Periodontal regeneration, treatment of periodontal-related diseases and improving the function of implants are global ther...
Protocol for Evaluating In Vivo the Activation of the P2RX7 Immunomodulator
Protocol for Evaluating In Vivo the Activation of the P2RX7 Immunomodulator
P2RX7 is a purinergic receptor with pleiotropic activities that is activated by high levels of extracellular ATP that are ...
The Critical Biomarkers Identification of Insulin Signaling Involved in Initiating cAMP Signaling Mediated Salivary Secretion in Sjogren Syndrome: Transcriptome Sequencing in NOD Mice Model
The Critical Biomarkers Identification of Insulin Signaling Involved in Initiating cAMP Signaling Mediated Salivary Secretion in Sjogren Syndrome: Transcriptome Sequencing in NOD Mice Model
Sjogren’s syndrome (SS) is an autoimmune disorder characterized by the destruction of exocrine glands, resulting in ...
Comprehensive Analysis of Cellular Senescence-Related Genes in Prognosis, Molecular Characterization and Immunotherapy of Hepatocellular Carcinoma
Comprehensive Analysis of Cellular Senescence-Related Genes in Prognosis, Molecular Characterization and Immunotherapy of Hepatocellular Carcinoma
Cellular senescence is a tumor suppressive response in which the cell cycle is in a state of permanent arrest and can inhi...
Clinical Prognostic Factors and Integrated Multi-Omics Studies Identify Potential Novel Therapeutic Targets for Pediatric Desmoid Tumor
Clinical Prognostic Factors and Integrated Multi-Omics Studies Identify Potential Novel Therapeutic Targets for Pediatric Desmoid Tumor
Desmoid tumor (DT), also known as desmoid-type fibromatosis (DTF) or aggressive fibromatosis (AF) is a rare mesenchymal tu...
Decoding the Virtual 2D Map of the Chloroplast Proteomes
Decoding the Virtual 2D Map of the Chloroplast Proteomes
The chloroplast is a semi-autonomous organelle having its own genome and corresponding proteome. Although chloroplast geno...
Genetic Analysis of Platelet-Related Genes in Hepatocellular Carcinoma Reveals a Novel Prognostic Signature and Determines PRKCD as the Potential Molecular Bridge
Genetic Analysis of Platelet-Related Genes in Hepatocellular Carcinoma Reveals a Novel Prognostic Signature and Determines PRKCD as the Potential Molecular Bridge
Hepatocellular carcinoma (HCC) belongs to a representative lethality gastrointestinal malignancy, and comprehensive manage...
The untargeted urine volatilome for biomedical applications: methodology and volatilome database
The untargeted urine volatilome for biomedical applications: methodology and volatilome database
Chemically diverse in compounds, urine can give us an insight into metabolic breakdown products from foods, drinks, drugs,...
Circadian gene CSNK1D promoted the progression of hepatocellular carcinoma by activating Wnt/β-catenin pathway via stabilizing Dishevelled Segment Polarity Protein 3
Circadian gene CSNK1D promoted the progression of hepatocellular carcinoma by activating Wnt/β-catenin pathway via stabilizing Dishevelled Segment Polarity Protein 3
A variety of studies have connected circadian rhythm to the initiation and progression of hepatocellular carcinoma (HCC). ...
Combating the menace of antimicrobial resistance in Africa: a review on stewardship, surveillance and diagnostic strategies
Combating the menace of antimicrobial resistance in Africa: a review on stewardship, surveillance and diagnostic strategies
The emergence of antibiotic-resistant pathogens has threatened not only our ability to deal with common infectious disease...
Analysis and Interpretation of metagenomics data: an approach
Analysis and Interpretation of metagenomics data: an approach
Advances in next-generation sequencing technologies have accelerated the momentum of metagenomic studies, which is increas...
Improved cytometric analysis of untouched lung leukocytes by enzymatic liquefaction of sputum samples
Improved cytometric analysis of untouched lung leukocytes by enzymatic liquefaction of sputum samples
Phenotyping sputum-resident leukocytes and evaluating their functional status are essential analyses for exploring the cel...
Angiotensin-converting enzyme 2 identifies immuno-hot tumors suggesting angiotensin-(1–7) as a sensitizer for chemotherapy and immunotherapy in breast cancer
Angiotensin-converting enzyme 2 identifies immuno-hot tumors suggesting angiotensin-(1–7) as a sensitizer for chemotherapy and immunotherapy in breast cancer
Angiotensin-converting enzyme 2 (ACE2) is known as a tumor suppressor and lowly expressed in most cancers. The expression ...
Shrimp miR-965 transfers tumoricidal mitochondria
Shrimp miR-965 transfers tumoricidal mitochondria
Micro RNA of Marsupenaeus japonicas has been known to promote apoptosis of tumor cells. However, the detailed mechanisms a...
Circ_0003570 Suppresses the progression of hepatocellular carcinoma through miR-182-5p/STARD13 regulatory axis
Circ_0003570 Suppresses the progression of hepatocellular carcinoma through miR-182-5p/STARD13 regulatory axis
Emerging evidence have revealed that circRNAs exert important biological effects in the development and progression of var...
Single-cell and WGCNA uncover a prognostic model and potential oncogenes in colorectal cancer
Single-cell and WGCNA uncover a prognostic model and potential oncogenes in colorectal cancer
Colorectal cancer (CRC) is one of the leading causes of cancer-related death worldwide. Single-cell transcriptome sequenci...
KDELR2-KIF20A axis facilitates bladder cancer growth and metastasis by enhancing Golgi-mediated secretion
KDELR2-KIF20A axis facilitates bladder cancer growth and metastasis by enhancing Golgi-mediated secretion
Bladder cancer (BCa) is a fatal form of cancer worldwide associated with a poor prognosis. Identifying novel drivers of gr...
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