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METABOLIC BRAIN DISEASE
Impact of stress hyperglycemia ratio, derived from glycated albumin or hemoglobin A1c, on mortality among ST-segment elevation myocardial infarction patients
Stress hyperglycemia ratio (SHR), associated with adverse outcomes in patients with ST-segment elevation myocardial infarc...
An elevated triglyceride-glucose index predicts adverse outcomes and interacts with the treatment strategy in patients with three-vessel disease
Insulin resistance is a pivotal risk factor for cardiovascular diseases, and the triglyceride-glucose (TyG) index is a wel...
Temporal relationship between triglyceride-glucose index and blood pressure and their joint cumulative effect on cardiovascular disease risk: a longitudinal cohort study
Concurrent insulin resistance and elevated blood pressure are commonly observed in cardiovascular disease (CVD) and have l...
Cost-effectiveness of screening of coronary artery disease in patients with type 2 diabetes at a very high cardiovascular risk (SCADIAB) study. Updated study design: emulation of a randomised target trial using electronic health records
Type 2 diabetes mellitus (T2DM) is a substantial health problem with a high clinical and economic burden [1, 2]. Despite a...
Effects of dapagliflozin and dapagliflozin-saxagliptin on erythropoiesis, iron and inflammation markers in patients with type 2 diabetes and chronic kidney disease: data from the DELIGHT trial
This post-hoc analysis of the DELIGHT trial assessed effects of the SGLT2 inhibitor dapagliflozin on iron metabolism and m...
Cost-effectiveness of finerenone in chronic kidney disease associated with type 2 diabetes in The Netherlands
In the Netherlands, more than one million patients have type 2 diabetes (T2D), and approximately 36% of these patients hav...
Safety and efficacy of bempedoic acid: a systematic review and meta-analysis of randomised controlled trials
Bempedoic Acid (BA) is a novel Lipid-Lowering Therapy (LLT). We performed a systematic review and meta-analysis to assess ...
Association between the triglyceride–glucose index and left ventricular global longitudinal strain in patients with coronary heart disease in Jilin Province, China: a cross-sectional study
This study aimed to investigate the association between the triglyceride–glucose (TyG) index and left ventricular gl...
Association of triglyceride glucose index with all-cause and cardiovascular mortality in the general population
The Triglyceride-glucose (TyG) index, a novel indicator of insulin resistance, has been associated with mortality from cor...
Once-weekly glucagon-like peptide-1 receptor agonists vs dipeptidyl peptidase-4 inhibitors: cardiovascular effects in people with diabetes and cardiovascular disease
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), which have proven cardiovascular benefits, are recommended in peopl...
Effects of diabetes mellitus on left ventricular function and deformation in patients with restrictive cardiomyopathies: a 3.0T CMR feature tracking study
Diabetes mellitus (DM) is the most common metabolic disease worldwide and a major risk factor for adverse cardiovascular e...
Machine learning identification of risk factors for heart failure in patients with diabetes mellitus with metabolic dysfunction associated steatotic liver disease (MASLD): the Silesia Diabetes-Heart Project
Diabetes mellitus (DM), heart failure (HF) and metabolic dysfunction associated steatotic liver disease (MASLD) are overla...
Diabetic microvascular disease in non-classical beds: the hidden impact beyond the retina, the kidney, and the peripheral nerves
Diabetes microangiopathy, a hallmark complication of diabetes, is characterised by structural and functional abnormalities...
Relationship between the cumulative exposure to atherogenic index of plasma and ischemic stroke: a retrospective cohort study
Atherogenic index of plasma (AIP) has been demonstrated as a surrogate marker for ischemic stroke, but there is limited ev...
Sodium-glucose cotransporter-2 inhibition for heart failure with preserved ejection fraction and chronic kidney disease with or without type 2 diabetes mellitus: a narrative review
Heart failure (HF), chronic kidney disease (CKD), and type 2 diabetes mellitus (T2DM) are common and interrelated conditio...
Association of glycemic variability with death and severe consciousness disturbance among critically ill patients with cerebrovascular disease: analysis of the MIMIC-IV database
The association of glycemic variability with severe consciousness disturbance and in-hospital all-cause mortality in criti...
Association between triglyceride glucose-body mass and one-year all-cause mortality of patients with heart failure: a retrospective study utilizing the MIMIC-IV database
The triglyceride glucose-body mass (TyG-BMI) index is acknowledged as both a reliable indicator of the risk of cardiovascu...
Triglycerides/HDL cholesterol ratio and type 2 diabetes incidence: Panasonic Cohort Study 10
Previous studies have investigated the association between the ratio of triglycerides (TG) to high-density lipoprotein cho...
Association between triglyceride-glucose index and in-hospital mortality in critically ill patients with sepsis: analysis of the MIMIC-IV database
This study aimed to explore the association between the triglyceride-glucose (TyG) index and the risk of in-hospital morta...
Association between insulin resistance and uncontrolled hypertension and arterial stiffness among US adults: a population-based study
Prior research has established the correlation between insulin resistance (IR) and hypertension. While the association bet...
Treatment with recombinant Sirt1 rewires the cardiac lipidome and rescues diabetes-related metabolic cardiomyopathy
Metabolic cardiomyopathy (MCM), characterized by intramyocardial lipid accumulation, drives the progression to heart failu...
Non-invasive detection of early microvascular changes in juveniles with type 1 diabetes
The study aimed to assess the usefulness of capillaroscopy and photoplethysmography in the search for early vascular anoma...
Triglyceride-glucose index is associated with severe obstructive coronary artery disease and atherosclerotic target lesion failure among young adults
Early diagnosis and treatment effectiveness of early-onset coronary artery disease (EOCAD) are crucial, and non-invasive p...
Triglyceride-glucose index is associated with recurrent revascularization in patients with type 2 diabetes mellitus after percutaneous coronary intervention
The Triglyceride-glucose (TyG) index, as a surrogate marker of insulin resistance, is independently associated with the se...
Impact of stress hyperglycemia ratio on mortality in patients with critical acute myocardial infarction: insight from american MIMIC-IV and the chinese CIN-II study
Among patients with acute coronary syndrome and percutaneous coronary intervention, stress hyperglycemia ratio (SHR) is pr...
Familial co-aggregation and shared genetics of cardiometabolic disorders and traits: data from the multi-generational Lifelines Cohort Study
It is unclear to what extent genetics explain the familial clustering and the co-occurrence of distinct cardiometabolic di...
Influence of diabetes mellitus on the pathological profile of aortic stenosis: a sex-based approach
Diabetes mellitus (DM) accelerates the progression of aortic stenosis (AS), but how their underlying molecular mechanisms ...
SGLT2 inhibition, circulating metabolites, and atrial fibrillation: a Mendelian randomization study
Sodium-glucose cotransporter 2 (SGLT2) inhibitors have shown promise in reducing the risk of atrial fibrillation (AF). How...
The triglyceride-glucose index is a predictor for cardiovascular and all-cause mortality in CVD patients with diabetes or pre-diabetes: evidence from NHANES 2001–2018
The association between the triglyceride-glucose (TyG) index and mortality in cardiovascular disease (CVD) patients with d...
Data from network meta-analyses can inform clinical practice guidelines and decision-making in diabetes management: perspectives of the taskforce of the guideline workshop
In recent years, several novel agents have become available to treat individuals with type 2 diabetes (T2D), such as sodiu...
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