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Revolutionizing acute myeloid leukemia treatment: a systematic review of immune-based therapies
Revolutionizing acute myeloid leukemia treatment: a systematic review of immune-based therapies
The established protocol for the management of acute myeloid leukemia (AML) has traditionally involved the administration ...
To describe the subsets of malignant epithelial cells in gastric cancer, their developmental trajectories and drug resistance characteristics
To describe the subsets of malignant epithelial cells in gastric cancer, their developmental trajectories and drug resistance characteristics
Gastric cancer is an aggressive malignancy characterized by significant clinical heterogeneity arising from complex geneti...
A pan-cancer analysis: predictive role of ZNF32 in cancer prognosis and immunotherapy response
A pan-cancer analysis: predictive role of ZNF32 in cancer prognosis and immunotherapy response
The zinc finger protein 32 (ZNF32) has been associated with high expression in various cancers, underscoring its significa...
Investigating causal relationship among inflammatory cytokines and oropharyngeal cancer: Mendelian randomization
Investigating causal relationship among inflammatory cytokines and oropharyngeal cancer: Mendelian randomization
This study aims to use Mendelian randomisation to identify the causal relationship between a spectrum of 41 inflammatory c...
Improving molecular subtypes and prognosis of pancreatic cancer through multi group analysis and machine learning
Improving molecular subtypes and prognosis of pancreatic cancer through multi group analysis and machine learning
Pancreatic cancer (PAC) has a complex tumor immune microenvironment, and currently, there is a lack of accurate personaliz...
A panel of cancer testis antigens in squamous cell carcinoma of the lung, head and neck, and esophagus: implication for biomarkers and therapeutic targets
A panel of cancer testis antigens in squamous cell carcinoma of the lung, head and neck, and esophagus: implication for biomarkers and therapeutic targets
This study aims to investigate the expression of seven cancer testis antigens (MAGE-A1, MAGE-A4, MAGE-A10, MAGE-A11, PRAME...
Bibliometric and visual analysis of chronic stress in cancer research from 2014 to 2024
Bibliometric and visual analysis of chronic stress in cancer research from 2014 to 2024
In today's fast-paced society, stress has become a widespread phenomenon, garnering increasing attention for its impac...
Inhibition of programmed cell death by melanoma cell subpopulations reveals mechanisms of melanoma metastasis and potential therapeutic targets
Inhibition of programmed cell death by melanoma cell subpopulations reveals mechanisms of melanoma metastasis and potential therapeutic targets
Melanoma is an aggressive type of skin cancer that arises from melanocytes, the cells responsible for producing skin pigme...
FadA antigen of Fusobacterium nucleatum: implications for ceRNA network in colorectal cancer and adenomatous polyps progression
FadA antigen of Fusobacterium nucleatum: implications for ceRNA network in colorectal cancer and adenomatous polyps progression
Colorectal cancer (CRC) is the second most common cause of cancer-related deaths globally. The gut microbiota, along with ...
Anticancer effect of the antirheumatic drug leflunomide on oral squamous cell carcinoma by the inhibition of tumor angiogenesis
Anticancer effect of the antirheumatic drug leflunomide on oral squamous cell carcinoma by the inhibition of tumor angiogenesis
Leflunomide (LEF) is a conventional synthetic disease-modifying antirheumatic drug and suppresses T-cell proliferation and...
Mutual causal effects between immune cells and hepatocellular carcinoma: a Mendelian randomization study
Mutual causal effects between immune cells and hepatocellular carcinoma: a Mendelian randomization study
Hepatocellular carcinoma (HCC), a malignant tumor that seriously endangering health, has aroused widespread concern in the...
RNA modification writer-based immunological profile and genomic landscape of tumor microenvironment in lung adenocarcinoma
RNA modification writer-based immunological profile and genomic landscape of tumor microenvironment in lung adenocarcinoma
Recent studies have highlighted the role of RNA modification, that is, the dysregulation of epitranscriptomics, in tumorig...
Combination therapy of low-dose radiotherapy and immunotherapy in advanced metastatic nasopharyngeal carcinoma: a case report and literature review
Combination therapy of low-dose radiotherapy and immunotherapy in advanced metastatic nasopharyngeal carcinoma: a case report and literature review
Nasopharyngeal cancer (NPC) is a common head and neck malignant tumor, which is difficult to treat at the advanced NPC due...
Therapeutic implications and comprehensive insights into cellular senescence and aging in the tumor microenvironment of sarcoma
Therapeutic implications and comprehensive insights into cellular senescence and aging in the tumor microenvironment of sarcoma
Sarcoma (SARC), a diverse group of stromal tumors arising from mesenchymal tissues, is often associated with a poor progno...
CAR-T therapy toxicities: the importance of macrophages in their development and possible targets for their management
CAR-T therapy toxicities: the importance of macrophages in their development and possible targets for their management
CAR-T cell therapies have risen to prominence over the last decade, and their indications are increasing with several prod...
Potential and development of cellular vesicle vaccines in cancer immunotherapy
Potential and development of cellular vesicle vaccines in cancer immunotherapy
Cancer vaccines are promising as an effective means of stimulating the immune system to clear tumors as well as to establi...
Elucidating stearoyl metabolism and NCOA4-mediated ferroptosis in gastric cancer liver metastasis through multi-omics single-cell integrative mendelian analysis: advancing personalized immunotherapy strategies
Elucidating stearoyl metabolism and NCOA4-mediated ferroptosis in gastric cancer liver metastasis through multi-omics single-cell integrative mendelian analysis: advancing personalized immunotherapy strategies
The metabolism of stearoyl-GPE plays a key role in the liver metastasis of gastric cancer. This investigation delves into ...
Exploring the mechanism of rosmarinic acid in the treatment of lung adenocarcinoma based on bioinformatics methods and experimental validation
Exploring the mechanism of rosmarinic acid in the treatment of lung adenocarcinoma based on bioinformatics methods and experimental validation
Rosmarinic acid (RosA) is a natural polyphenol compound that has been shown to be effective in the treatment of inflammato...
Combination of inflammatory proteins in serum can be used to diagnose papillary thyroid carcinoma with lymph node metastasis
Combination of inflammatory proteins in serum can be used to diagnose papillary thyroid carcinoma with lymph node metastasis
Accurately distinguishing lymph node metastases (LNM) from papillary thyroid carcinomas (PTC) is crucial in clinical pract...
Targeting protein synthesis pathways in MYC-amplified medulloblastoma
Targeting protein synthesis pathways in MYC-amplified medulloblastoma
MYC is one of the most deregulated oncogenic transcription factors in human cancers. MYC amplification/or overexpression i...
Analysis of mRNA Pentatricopeptide Repeat Domain 1 as a prospective oncogene in clear cell renal cell carcinoma that accelerates tumor cells proliferation and invasion via the Akt/GSK3β/β-catenin pathway
Analysis of mRNA Pentatricopeptide Repeat Domain 1 as a prospective oncogene in clear cell renal cell carcinoma that accelerates tumor cells proliferation and invasion via the Akt/GSK3β/β-catenin pathway
Although pentatricopeptide repeat domain 1 (PTCD1) has been found to modulate mitochondrial metabolic and oxidative phosph...
Bioinformation study of immune microenvironment characteristics of disulfidptosis-related subtypes in ovarian cancer and prognostic model construction
Bioinformation study of immune microenvironment characteristics of disulfidptosis-related subtypes in ovarian cancer and prognostic model construction
Ovarian cancer significantly impacts women's reproductive health and remains challenging to diagnose and treat. Despit...
Analysis of exportins expression unveils their prognostic significance in colon adenocarcinoma: insights from public databases
Analysis of exportins expression unveils their prognostic significance in colon adenocarcinoma: insights from public databases
Colon cancer remains a significant health burden globally, necessitating deeper investigation. Identification and targetin...
MUC5B regulates alterations in the immune microenvironment in nasopharyngeal carcinoma via the Wnt/β-catenin signaling pathway
MUC5B regulates alterations in the immune microenvironment in nasopharyngeal carcinoma via the Wnt/β-catenin signaling pathway
To screen potential differentially expressed genes related to immune function in nasopharyngeal carcinoma through an onlin...
Environmental factors inducing gastric cancer: insights into risk and prevention strategies
Environmental factors inducing gastric cancer: insights into risk and prevention strategies
Gastric cancer, a prevalent malignant tumor worldwide, poses a significant challenge to global health. Despite ongoing adv...
Surgical treatment can provide the opportunity for in-vitro fertilization (IVF) in a shorter period of time for patients with early-stage endometrial cancer
Surgical treatment can provide the opportunity for in-vitro fertilization (IVF) in a shorter period of time for patients with early-stage endometrial cancer
Whether localized surgical treatment has advantages over traditional hormone therapy for young women who desire to preserv...
Single-cell RNA-sequencing and genome-wide Mendelian randomisation along with abundant machine learning methods identify a novel B cells signature in gastric cancer
Single-cell RNA-sequencing and genome-wide Mendelian randomisation along with abundant machine learning methods identify a novel B cells signature in gastric cancer
Gastric cancer (GC) has a poor prognosis, considerable cellular heterogeneity, and ranks fifth among malignant tumours. Un...
Vitamin A and its influence on tumour extracellular matrix
Vitamin A and its influence on tumour extracellular matrix
Vitamin A is a crucial nutrient renowned for its role in visual health and cellular regulation. Its derivatives influence ...
Role of arbutin in the inhibition of FBXO5 in hepatocellular carcinoma
Role of arbutin in the inhibition of FBXO5 in hepatocellular carcinoma
This work investigated the effect of FBXO5 in hepatocellular carcinoma (HCC) and the mechanism of action of arbutin in its...
Nuclear receptor profiling for subtype classification and as prognostic markers in 33 cancer types
Nuclear receptor profiling for subtype classification and as prognostic markers in 33 cancer types
Nuclear receptors, a group of 48 transcription factors that regulate a multitude of processes within our body, have long b...
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