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Synergistic metabolic modulation of fibroblast-like synoviocytes via targeted dual prodrug nanoparticles to mitigate rheumatoid arthritis
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Cocrystal pleomorphism-inspired drug nanoassembly for pulmonary-endothelium targeting and pulmonary hypertension treatment
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Author correction to ‘The novel ER stress inducer Sec C triggers apoptosis by sulfating ER cysteine residues and degrading YAP via ER stress in pancreatic cancer cells’ [Acta Pharm Sin B 12 (2022) 210–227]
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Neuronal activities drive brain metabolite clearance through the glymphatic system
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A microfluidic coculture model for mapping signaling perturbations and precise drug screening against macrophage-mediated dynamic myocardial injury
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The applications and advances of artificial intelligence in drug regulation: A global perspective
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Thio-ProTide strategy: a novel H2S donor–drug conjugate (DDC) alleviates hepatic injury via innate lysosomal targeting
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Induction of Cyp2e1 contributes to asparaginase-induced hepatocyte sensitization to lipotoxicity
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Reversing metabolic reprogramming by CPT1 inhibition with etomoxir promotes cardiomyocyte proliferation and heart regeneration via DUSP1 ADP-ribosylation-mediated p38 MAPK phosphorylation
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N6-Methyladenosine modification of circDcbld2 in Kupffer cells promotes hepatic fibrosis via targeting miR-144-3p/Et-1 axis
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Safety, pharmacokinetics, and dosimetry of 177Lu-AB-3PRGD2 in patients with advanced integrin αvβ3-positive tumors: a first-in-human study
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Bispecific killer engager for targeted depletion of PD-1 positive lymphocytes: A new avenue for autoimmune disease treatment
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Respiratory delivered vaccines: Current status and perspectives in rational formulation design
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Tumor-intrinsic PRMT5 upregulates FGL1 via methylating TCF12 to inhibit CD8+ T-cell-mediated antitumor immunity in liver cancer
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Recent advances in reactive oxygen species (ROS)-responsive drug delivery systems for photodynamic therapy of cancer
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Author correction to ‘The novel ER stress inducer Sec C triggers apoptosis by sulfating ER cysteine residues and degrading YAP via ER stress in pancreatic cancer cells’ [Acta Pharmaceutica Sinica B 12 (2022) 210-227]
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FLZ attenuates Parkinson’s disease pathological damage by increasing glycoursodeoxycholic acid production via down-regulating Clostridium innocuum
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Akkermansia muciniphila-derived acetate activates the hepatic AMPK/SIRT1/PGC-1α axis to alleviate ferroptosis in metabolic-associated fatty liver disease
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Microglial APOE4 promotes neuron degeneration in Alzheimer’s disease through inhibition of lipid droplet autophagy
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Inhibition of liver cholesterol synthesis by a diet-induced gut hormone
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Activating autophagy improves paclitaxel-induced peripheral neuropathy in chemotherapy
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Aclysiran, an RNAi therapeutic agent targeting ACLY, treats hypercholesterolemia and atherosclerosis in ApoE–/– mice
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New functions of oxylipins released by pyroptotic cells
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Discovery of a novel AhR–CYP1A1 axis activator for mitigating inflammatory diseases using an in situ functional imaging assay
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Discovery of a novel thiophene carboxamide analogue as a highly potent and selective sphingomyelin synthase 2 inhibitor for dry eye disease therapy
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Iron and siRNA co-encapsulated ferritin nanocages induce ferroptosis synergistically for cancer therapy
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Targeted inhibition of Gus-expressing Enterococcus faecalis to promote intestinal stem cell and epithelial renovation contributes to the relief of irinotecan chemotoxicity by dehydrodiisoeugenol
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Dimeric natural product panepocyclinol A inhibits STAT3 via di-covalent modification
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Design, synthesis and pharmacological evaluation of 1,2,3,4-tetrahydrobenzofuro[2,3-c]pyridine derivatives as p21-activated kinase 4 inhibitors for treatment of pancreatic cancer
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Regulation of histidine metabolism by Lactobacillus Reuteri mediates the pathogenesis and treatment of ischemic stroke
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