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Author correction to “Tumor-microenvironment activated duplex genome-editing nanoprodrug for sensitized near-infrared titania phototherapy” [Acta Pharm Sin B 12 (2022) 4224–4234]
Author correction to “Tumor-microenvironment activated duplex genome-editing nanoprodrug for sensitized near-infrared titania phototherapy” [Acta Pharm Sin B 12 (2022) 4224–4234]
Available online 7 September 2023Author links open overlay panelZekun Li a †, Yongchun Pan b †, Shiyu Du a, Yayao Li a, Ch...
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood–brain barrier and exhibits potent activity against glioblastoma
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood–brain barrier and exhibits potent activity against glioblastoma
Small molecule inhibitorGlioblastomaVEGFRCSF1RAngiogenesisMacrophageTumor microenvironmentImmune-checkpoint inhibitor© 202...
Photo-induced crosslinked and anti-PD-L1 peptide incorporated liposomes to promote PD-L1 multivalent binding for effective immune checkpoint blockade therapy
Photo-induced crosslinked and anti-PD-L1 peptide incorporated liposomes to promote PD-L1 multivalent binding for effective immune checkpoint blockade therapy
Cancer immunotherapyImmune checkpoint blockadePEGylated liposomeCrosslinked lipid nanoparticlesAnti-PD-L1 peptideTumor-tar...
Gut microbiota-derived short-chain fatty acids ameliorate methamphetamine-induced depression- and anxiety-like behaviors in a Sigmar-1 receptor-dependent manner
Gut microbiota-derived short-chain fatty acids ameliorate methamphetamine-induced depression- and anxiety-like behaviors in a Sigmar-1 receptor-dependent manner
Available online 21 September 2023Author links open overlay panel, , , , , , , , , , , AbstractMethamphetamine (Meth) abus...
TBC1D15 deficiency protects against doxorubicin cardiotoxicity via inhibiting DNA-PKcs cytosolic retention and DNA damage
TBC1D15 deficiency protects against doxorubicin cardiotoxicity via inhibiting DNA-PKcs cytosolic retention and DNA damage
Clinical application of doxorubicin (DOX) is heavily hindered by DOX cardiotoxicity. Several theories were postulated for ...
Disulfide bridge-targeted metabolome mining unravels an antiparkinsonian peptide
Disulfide bridge-targeted metabolome mining unravels an antiparkinsonian peptide
Available online 19 September 2023Author links open overlay panel, , , , , , , , AbstractPeptides are a particular molecul...
Metabolic basis of solute carrier transporters in treatment of type 2 diabetes mellitus
Metabolic basis of solute carrier transporters in treatment of type 2 diabetes mellitus
Solute carriers (SLCs) constitute the largest superfamily of membrane transporter proteins. These transporters, present in...
ACAT1 deficiency in myeloid cells promotes glioblastoma progression by enhancing accumulation of myeloid-derived suppressors cells metabolism
ACAT1 deficiency in myeloid cells promotes glioblastoma progression by enhancing accumulation of myeloid-derived suppressors cells metabolism
GlioblastomaMyeloid cellsMyeloid-derived suppressor cellsAcetyl-CoA acetyltransferase 1CXCL1Tumor microenvironmentLipid me...
Overview of epigenetic degraders based on PROTAC, molecular glue, and hydrophobic tagging technologies
Overview of epigenetic degraders based on PROTAC, molecular glue, and hydrophobic tagging technologies
Epigenetic pathways play a critical role in the initiation, progression, and metastasis of cancer. Over the past few decad...
Discovery and druggability evaluation of pyrrolamide-type GyrB/ParE inhibitor against drug-resistant bacterial infection
Discovery and druggability evaluation of pyrrolamide-type GyrB/ParE inhibitor against drug-resistant bacterial infection
Available online 9 September 2023Author links open overlay panel, , , , , , , , , , , , , , , , , , , …AbstractThe bacteri...
pH-Responsive polymer boosts cytosolic siRNA release for retinal neovascularization therapy
pH-Responsive polymer boosts cytosolic siRNA release for retinal neovascularization therapy
siRNAOcular delivery systemBlock polymerEndosomal escapeRetinal neovascularizationBlood‒retinal barrierVEGFASafety© 2023 C...
Identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1α/XBP-1s axis and JNK signaling
Identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1α/XBP-1s axis and JNK signaling
Available online 9 September 2023Author links open overlay panel, , , , , , , , , , , Abstract:Lipotoxicity is a pivotal f...
Cancer immunotherapy with enveloped self-amplifying mRNA CARG-2020 that modulates IL-12, IL-17 and PD-L1 pathways to prevent tumor recurrence
Cancer immunotherapy with enveloped self-amplifying mRNA CARG-2020 that modulates IL-12, IL-17 and PD-L1 pathways to prevent tumor recurrence
Available online 9 September 2023Author links open overlay panel, , , , , , , , , , , , AbstractTargeting multiple immune ...
Author correction to ‘Amino-functionalized poloxamer 407 with both mucoadhesive and thermosensitive properties: Preparation, characterization and application in vaginal drug delivery system’ [Acta Pharm Sin B 7 (2017) 593–602]
Author correction to ‘Amino-functionalized poloxamer 407 with both mucoadhesive and thermosensitive properties: Preparation, characterization and application in vaginal drug delivery system’ [Acta Pharm Sin B 7 (2017) 593–602]
Volume 13, Issue 9, September 2023, Pages 3961-3962Author links open overlay panelLi-qian Ci a, Zhi-gang Huang b, Yu Liu b...
Author correction to ‘Tumor-microenvironment activated duplex genome-editing nanoprodrug for sensitized near-infrared titania phototherapy’ [Acta Pharm Sin B 13 (2022) 4224-4234]
Author correction to ‘Tumor-microenvironment activated duplex genome-editing nanoprodrug for sensitized near-infrared titania phototherapy’ [Acta Pharm Sin B 13 (2022) 4224-4234]
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Boosting synergism of chemo- and immuno-therapies via switching paclitaxel-induced apoptosis to mevalonate metabolism-triggered ferroptosis by bisphosphonate coordination lipid nanogranules
Boosting synergism of chemo- and immuno-therapies via switching paclitaxel-induced apoptosis to mevalonate metabolism-triggered ferroptosis by bisphosphonate coordination lipid nanogranules
Bisphosphonate coordination lipid nanogranulesFerroptosisMevalonate metabolismMitochondrial metabolismNano-systematic biol...
Converting bacteria into autologous tumor vaccine via surface biomineralization of calcium carbonate for enhanced immunotherapy
Converting bacteria into autologous tumor vaccine via surface biomineralization of calcium carbonate for enhanced immunotherapy
bacteria-mediated cancer therapyTumor microenvironmentCalcium carbonateMineralizationMetalloimmunologyAutologous tumor vac...
Unlocking the potential of amorphous calcium carbonate: A star ascending in the realm of biomedical application
Unlocking the potential of amorphous calcium carbonate: A star ascending in the realm of biomedical application
Amorphous calcium carbonateDrug delivery systemsNanoparticlesAcid sensitivityWater instabilityTumor therapyTissue engineer...
Plant-derived nanovesicles as an emerging platform for cancer therapy
Plant-derived nanovesicles as an emerging platform for cancer therapy
Plant-derived nanovesicles (PDNVs) derived from natural green products have emerged as an attractive nanoplatform in biome...
Metal nanoparticles for cancer therapy: Precision targeting of DNA damage
Metal nanoparticles for cancer therapy: Precision targeting of DNA damage
Available online 3 September 2023Author links open overlay panel, , , , , AbstractCancer, a complex and heterogeneous dise...
Genomics-driven derivatization of the bioactive fungal sesterterpenoid variecolin: Creation of an unnatural analogue with improved anticancer properties
Genomics-driven derivatization of the bioactive fungal sesterterpenoid variecolin: Creation of an unnatural analogue with improved anticancer properties
Available online 30 August 2023Author links open overlay panel, , , , , , , , , , , , , , , , , , , …AbstractA biosyntheti...
Author correction to ‘Cascade Two-stage Tumor Re-oxygenation and Immune Re-sensitization Mediated by Self-Assembled Albumin-Sorafenib Nanoparticles for Enhanced Photodynamic Immunotherapy’ [Acta Pharmaceutica Sinica B 2022;12(11):4204-4223]
Author correction to ‘Cascade Two-stage Tumor Re-oxygenation and Immune Re-sensitization Mediated by Self-Assembled Albumin-Sorafenib Nanoparticles for Enhanced Photodynamic Immunotherapy’ [Acta Pharmaceutica Sinica B 2022;12(11):4204-4223]
Available online 31 August 2023Author links open overlay panelZaigang Zhou a d 1, Jiashe Chen b 1, Yu Liu a 1, Chunjuan Zh...
Emerging delivery systems based on aqueous two-phase systems: A review
Emerging delivery systems based on aqueous two-phase systems: A review
Aqueous two-phase systemsDrug delivery systemsBiomaterialsMicrocapsulesMicroparticlesCell therapyCancer treatmentOrgan reg...
Immunogenicity of mucosal COVID-19 vaccine candidates based on the highly attenuated vesicular stomatitis virus vector (VSVMT) in golden syrian hamster
Immunogenicity of mucosal COVID-19 vaccine candidates based on the highly attenuated vesicular stomatitis virus vector (VSVMT) in golden syrian hamster
COVID-19Vesicular stomatitis virusMatrix protein mutantMucosalVaccineSpike proteinVariants of concernsIntranasal inoculati...
Mitochondria-specific near-infrared photoactivation of peroxynitrite upconversion luminescent nanogenerator for precision cancer gas therapy
Mitochondria-specific near-infrared photoactivation of peroxynitrite upconversion luminescent nanogenerator for precision cancer gas therapy
Near infraredPhoto-triggeredMitochondrionUpconversion luminescent bioimagingPeroxynitriteNanogeneratorGas therapyIn vivo© ...
Translating bacteriophage-derived depolymerases into antibacterial therapeutics: Challenges and prospects
Translating bacteriophage-derived depolymerases into antibacterial therapeutics: Challenges and prospects
Phage-derived polysaccharide depolymerasesBacteriophage proteinsBacterial capsulesPolysaccharide capsulesAntibiotic resist...
Hippo pathway-manipulating neutrophil-mimic hybrid nanoparticles for cardiac ischemic injury via modulation of local immunity and cardiac regeneration
Hippo pathway-manipulating neutrophil-mimic hybrid nanoparticles for cardiac ischemic injury via modulation of local immunity and cardiac regeneration
Available online 19 August 2023Author links open overlay panel, , , , , , , , , , , , , AbstractThe promise of regeneratio...
Cancer cell membrane-coated bacterial ghosts for highly efficient paclitaxel delivery against metastatic lung cancer
Cancer cell membrane-coated bacterial ghosts for highly efficient paclitaxel delivery against metastatic lung cancer
Available online 19 August 2023Author links open overlay panel, , , , , , , AbstractChemotherapy is one of the major appro...
Immunostimulatory gene therapy combined with checkpoint blockade reshapes tumor microenvironment and enhances ovarian cancer immunotherapy
Immunostimulatory gene therapy combined with checkpoint blockade reshapes tumor microenvironment and enhances ovarian cancer immunotherapy
Available online 19 August 2023Author links open overlay panel, , , , , , , , , , AbstractImmune evasion has made ovarian ...
Remodeling of the liver fibrosis microenvironment based on nilotinib-loaded multicatalytic nanozymes with boosted antifibrogenic activity
Remodeling of the liver fibrosis microenvironment based on nilotinib-loaded multicatalytic nanozymes with boosted antifibrogenic activity
Liver fibrosis is a reversible pathological process caused by chronic liver damage and a major risk factor for hepatocellu...
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