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Anticancer activity of NFκB decoy oligonucleotide-loaded nanoparticles against human lung cancer
Non-small cell lung cancer (NSCLC) is among the leading global causes of cancer-related mortality. Current treatment optio...
Tackling the cytokine storm using advanced drug delivery in allergic airway disease
Asthma is one of the leading causes of mortality worldwide presenting a huge socio-economic burden with rising morbidity a...
Oral lyophilizates obtained using aggressive drying conditions: Effect of excipients
Orodispersible drug formulations are a current trend in the pharmaceutical industry, mostly intended for pediatric and ger...
3-Carene-loaded poloxamer micelles against Leishmania: Development, characterization and in vitro proof-of-concept
Leishmaniases are parasitic diseases that affect millions of people around the world. Pharmacotherapy has limitations emph...
A comparison between optimized PLGA and CS-Alg-PLGA microspheres for long-lasting release of glatiramer acetate
Glatiramer acetate (GA, Copaxone, COP, Copolymer-1) is one of the most prescribed drugs to treat relapsing-remitting multi...
Fabrication of bergenin nanoparticles based hydrogel against infected wounds: An In vitro and In vivo study
The present study was aimed to fabricate bergenin polymeric nanoparticles based hydrogel and to evaluate its therapeutic e...
Micronization of naringenin in supercritical fluid medium: In vitro and in vivo assays
Naringenin is a citrus flavonoid that shows relevant biological actions. However, naringenin presents low solubility in wa...
Selective targeting of gold nanoparticles for radiosensitization of somatostatin 2 receptor-expressing cancer cells
Lanreotide peptide (LP), a somatostatin analog with high affinity towards somatostatin receptor 2 (SSTR2) is commonly used...
Pulmonary delivery of curcumin and quercetin nanoparticles for lung cancer – Part 2: Toxicity and endocytosis
The delivery of polyphenol compounds via inhalation to treat lung cancer is attractive to enable high drug concentration i...
Development of doxycycline and atorvastatin-loaded chitosan nanoparticles for local delivery in periodontal disease
The effectiveness of the local treatment depends on the ability of the release system to deliver drugs efficiently as well...
Antisolvent Eudragit® polymers based in situ forming gel for periodontal controlled drug delivery
In situ forming gel (ISG) is relevant for periodontal pocket drug delivery because of its local administration with sustai...