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In vitro and in vivo evaluation of isoxsuprine loaded invasomes for efficient treatment of diabetes‐accelerated atherosclerosis
In vitro and in vivo evaluation of isoxsuprine loaded invasomes for efficient treatment of diabetes‐accelerated atherosclerosis
Diabetes mellitus is a chronic metabolic condition marked by hyperglycemia [[1], [2], [3]]. It's one of the most prominent...
Cellulose nanocrystals as an innovative superdisintegrant for oral dispersible tablets
Cellulose nanocrystals as an innovative superdisintegrant for oral dispersible tablets
Oral administration is the most used drug delivery route. Oral dispersible tablets (ODTs) are single-unit dosage forms des...
Transforming cancer care: Immunotherapy with advanced drug delivery
Transforming cancer care: Immunotherapy with advanced drug delivery
Cancer immunotherapy represents an invasive therapeutic approach that orchestrates the body's immune system to combat mali...
Bergenin nano-lipid carrier to improve the oral delivery: Development, optimization, in vitro and in vivo evaluation
Bergenin nano-lipid carrier to improve the oral delivery: Development, optimization, in vitro and in vivo evaluation
The oral route is the utmost common and preferable route for the delivery of therapeutic agents. It has many advantages ov...
Enhancement of in-vivo cellular uptake of Coenzyme Q10 using saponin derivatives in rTALAP transgenic mice model
Enhancement of in-vivo cellular uptake of Coenzyme Q10 using saponin derivatives in rTALAP transgenic mice model
Pancreatic cancer, a prominent cause of cancer-related deaths in both men and women, ranks among the top cancers associate...
Preparation of antibody-loaded protein microbeads for pulmonary delivery via Shirasu porous glass membrane emulsification and freeze drying
Preparation of antibody-loaded protein microbeads for pulmonary delivery via Shirasu porous glass membrane emulsification and freeze drying
Most therapeutic proteins are vulnerable to physicochemical degradation as exposed to pH change and digestive enzymes, and...
Pharmacodynamic study: Astragaloside IV/chitosan/polylactic acid composite electrospinning scaffold for wound healing in diabetic rats
Pharmacodynamic study: Astragaloside IV/chitosan/polylactic acid composite electrospinning scaffold for wound healing in diabetic rats
With the improvement of living standards, the changes in diet structure, and the aging of the population, the prevalence o...
Evaluation of preclinical efficacy of apremilast-loaded liquid crystalline nanoparticulate gel in amelioration of atopic dermatitis
Evaluation of preclinical efficacy of apremilast-loaded liquid crystalline nanoparticulate gel in amelioration of atopic dermatitis
Phosphodiesterase (PDE)-4 is an enzyme responsible for the activity of various inflammatory cytokines. The increased level...
BBD assisted in-situ nanoliposomes of esculin hydrate via intranasal delivery for the amelioration of Parkinson's disease
BBD assisted in-situ nanoliposomes of esculin hydrate via intranasal delivery for the amelioration of Parkinson's disease
Parkinson's disease (PD) is a rapid neurodegenerative disorder of central nervous system (CNS caused by the reduction in l...
Nanotechnology invigorated drug delivery and tissue engineering strategies for the management of diabetic foot ulcers: Therapeutic approaches and clinical applications
Nanotechnology invigorated drug delivery and tissue engineering strategies for the management of diabetic foot ulcers: Therapeutic approaches and clinical applications
Volume 96, June 2024, 105665Author links open overlay panel, , , , , , , AbstractDiabetic foot ulcers (DFUs) are multifact...
Magnetic nanoparticles and their hybrid biomaterials for drug delivery and theranostic applications in cardiovascular diseases
Magnetic nanoparticles and their hybrid biomaterials for drug delivery and theranostic applications in cardiovascular diseases
Cardiovascular diseases (CVDs) remain a significant global health concern, as indicated by numerous studies [1]. Worldwide...
αvβ3 integrin targeting RGD peptide-based nanoparticles as an effective strategy for selective drug delivery to tumor microenvironment
αvβ3 integrin targeting RGD peptide-based nanoparticles as an effective strategy for selective drug delivery to tumor microenvironment
Cancer is the second greatest cause of mortality worldwide and a serious health concern and is characterized by the uncont...
Salvia coccinea Buc'hoz ex Etl. Leaf extract mediated synthesis of zinc oxide nanoparticles: Assessment of antimicrobial, antioxidant and anticancer activity
Salvia coccinea Buc'hoz ex Etl. Leaf extract mediated synthesis of zinc oxide nanoparticles: Assessment of antimicrobial, antioxidant and anticancer activity
Medicinal plants have a long history of usage in traditional medicine to ancient times. These plants have been utilized in...
Development and in vitro evaluation of liposomal carnosine for dermatological and cosmeceutical applications
Development and in vitro evaluation of liposomal carnosine for dermatological and cosmeceutical applications
Carnosine (β-alanyl- l-histidine) is a water-soluble dipeptide characterized by three ionizable groups [1,2]. The molecule...
Development, optimization, in-vitro, and in-vivo evaluation of chitosan-inlayed nano-spanlastics encompassing lercanidipine HCl for enhancement of bioavailability
Development, optimization, in-vitro, and in-vivo evaluation of chitosan-inlayed nano-spanlastics encompassing lercanidipine HCl for enhancement of bioavailability
Oral drug administration is regarded as the most popular, convenient, and widespread mode of administration. It has variou...
Synthesis of naringenin-betaine cocrystal by gas antisolvent technique and cell models for in vitro permeation studies
Synthesis of naringenin-betaine cocrystal by gas antisolvent technique and cell models for in vitro permeation studies
Naringenin (NRG, C15H12O5, 4′,5,7- trihydroxyflavanone, molecular weight 272.25 g/mol, Scheme 1) is a naturally occurring ...
Biodegradable SPI-based hydrogel for controlled release of nanomedicines: A potential approach against brain tumors recurrence
Biodegradable SPI-based hydrogel for controlled release of nanomedicines: A potential approach against brain tumors recurrence
Glioblastoma (GB) is the most common and aggressive brain tumor. The treatment for newly diagnosed glioblastoma is surgica...
Development of ginger-derived extracellular vesicles thermosensitive gel for UVA-induced photodamage of skin
Development of ginger-derived extracellular vesicles thermosensitive gel for UVA-induced photodamage of skin
Extracellular vesicles (EVs) are lipid bilayer vesicles that are secreted from almost all cell types, serve as “messengers...
Evaluation of ZnO nanoparticles from ‘Monsooned Malabar Robusta Coffee’ husk as a potential antioxidant and biocidal candidate: A sustainable valorization approach
Evaluation of ZnO nanoparticles from ‘Monsooned Malabar Robusta Coffee’ husk as a potential antioxidant and biocidal candidate: A sustainable valorization approach
In recent times, agricultural production has skyrocketed due to the impact of the green revolution and technological advan...
Recent progress in macromolecules: From current therapeutic strategies to theranostic applications
Recent progress in macromolecules: From current therapeutic strategies to theranostic applications
Volume 96, June 2024, 105664Author links open overlay panel, , , , , AbstractMacromolecules, specifically peptides, protei...
Quercetin-loaded transliposomal gel for effective management of skin cancer: In vitro and cell line efficacy studies
Quercetin-loaded transliposomal gel for effective management of skin cancer: In vitro and cell line efficacy studies
Skin carcinoma is a highly perilous form of cancer that was initially documented by Laennec in 1804 for melanoma, Jacob in...
Preparation and characterization of injectable in-situ forming gel based on lipid liquid crystal for one month delivery of aripiprazole: In-vitro and in-vivo evaluations in rats
Preparation and characterization of injectable in-situ forming gel based on lipid liquid crystal for one month delivery of aripiprazole: In-vitro and in-vivo evaluations in rats
Aripiprazole, marketed under the brand name Abilify®, belongs to the class of atypical antipsychotics. It functions as a p...
Enhancement of transdermal vaccination using electrothermal active interfaces
Enhancement of transdermal vaccination using electrothermal active interfaces
Vaccination is a vital healthcare strategy for preventing and controlling infectious diseases in humans and animals [1,2]....
“Nano-in-Micro” Structured Dry Powder Inhalers for pulmonary delivery: Advances and challenges
“Nano-in-Micro” Structured Dry Powder Inhalers for pulmonary delivery: Advances and challenges
Lung diseases, including COVID-19, pneumonia, chronic obstructive pulmonary disease (COPD), asthma, lung cancer, cystic fi...
Vascular normalization with pegylated emulsion of SU5416 enhances anti-tumor effect of liposomal paclitaxel in 4T1 breast cancer-bearing mice: Analysis of intratumoral vessels and microenvironment
Vascular normalization with pegylated emulsion of SU5416 enhances anti-tumor effect of liposomal paclitaxel in 4T1 breast cancer-bearing mice: Analysis of intratumoral vessels and microenvironment
Cancer cells induce angiogenesis for themselves to obtain oxygen and nutrients for the growth and metastasis of solid tumo...
A facile carrier-free co-assembly nanoplatform for effective enhanced oral chemotherapy
A facile carrier-free co-assembly nanoplatform for effective enhanced oral chemotherapy
Oral chemotherapy is the most potential therapeutic mode due to its convenience [1,2], while the mucus barrier, intestinal...
Application of ultrasound-assisted compression and 3D-printing semi-solid extrusion techniques to the development of sustained-release drug delivery systems based on a novel biodegradable aliphatic copolyester
Application of ultrasound-assisted compression and 3D-printing semi-solid extrusion techniques to the development of sustained-release drug delivery systems based on a novel biodegradable aliphatic copolyester
The purpose of this study was to investigate the ability of two advanced hot-processing technologies, Ultrasound-Assisted ...
Rapamycin loaded in yeast-derived glucan particles promoted tumour cell apoptosis and the antitumour immune response in melanoma
Rapamycin loaded in yeast-derived glucan particles promoted tumour cell apoptosis and the antitumour immune response in melanoma
Mammalian target of rapamycin (mTOR) has recently emerged as a promising target for the treatment of several human cancer ...
Sirolimus micro/nano particles coated drug-eluting stents using QbD paradigm: Potential approach for the amelioration of arterial diseases
Sirolimus micro/nano particles coated drug-eluting stents using QbD paradigm: Potential approach for the amelioration of arterial diseases
Arterial diseases, characterized by their chronic and progressive nature, are hallmarked by the atherosclerotic occlusion ...
Biocompatible graphene oxide/carboxymethylated chitosan nanocomposite hydrogel for controlled release of polyphenolic antioxidants
Biocompatible graphene oxide/carboxymethylated chitosan nanocomposite hydrogel for controlled release of polyphenolic antioxidants
Cancer, characterized by the uncontrolled proliferation of cells, remains a formidable global health challenge and ranks a...
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