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Developmental regulation of primitive erythropoiesis
Developmental regulation of primitive erythropoiesis
Purpose of review In this review, we present an overview of recent studies of primitive erythropo
Mixed donor chimerism following stem cell transplantation for sickle cell disease
Mixed donor chimerism following stem cell transplantation for sickle cell disease
Sickle cell disease is a debilitating hemoglobinopathy with high morbidity and mortality. Hematopoie
In-vivo functions and regulation of polyphosphate in the vascular system
In-vivo functions and regulation of polyphosphate in the vascular system
Purpose of review Polyphosphate, an inorganic polymer consisting of linearly linked phosphate sub
Platelet mitochondria: the mighty few
Platelet mitochondria: the mighty few
Purpose of review Platelet mitochondrial dysfunction is both caused by, as well as a source of ox
The impact of prenatal inflammation on hematopoietic development
The impact of prenatal inflammation on hematopoietic development
Purpose of review Inflammation is now recognized as a major regulator of hematopoietic stem cell
Haematopoietic stem cell quiescence exposed using mitochondrial membrane potential
Haematopoietic stem cell quiescence exposed using mitochondrial membrane potential
Purpose of review Quiescence is a fundamental property of haematopoietic stem cells (HSCs). Despi
Immunologic effects of red blood cell and platelet transfusions in neonates
Immunologic effects of red blood cell and platelet transfusions in neonates
Purpose of Review Premature neonates are frequently transfused red blood cells (RBCs) or platelet
Global perspectives on cellular therapy for children with sickle cell disease
Global perspectives on cellular therapy for children with sickle cell disease
Purpose of review Low-income and middle-income countries (LMICs), primarily in sub-Saharan Africa
Recent advances in factor XII structure and function
Recent advances in factor XII structure and function
Purpose of review Factor XII (FXII), the precursor of the protease FXIIa, contributes to patholog
Fibrin structure, viscoelasticity and lysis face the interplay of biorelevant polyions
Fibrin structure, viscoelasticity and lysis face the interplay of biorelevant polyions
Purpose of review In the past 5 decades, heparins have been widely used as anticoagulants in the
The protein C pathways
The protein C pathways
Purpose of review To provide an overview of the state-of-the-art in protein C (PC) pathway resear
Complement contributions to COVID-19
Complement contributions to COVID-19
Purpose of review COVID-19 remains a major source of concern, particularly as new variants emerge
The new metabolic needs of hematopoietic stem cells
The new metabolic needs of hematopoietic stem cells
Purpose of review Hematopoietic stem cells (HSCs) are endowed with high regenerative potential to
Local and systemic features of ILC immunometabolism
Local and systemic features of ILC immunometabolism
Purpose of review Innate lymphoid cells (ILCs) are specialized immune cells that rapidly sense en
Alteration of interleukin-10-producing Type 1 regulatory cells in autoimmune diseases
Alteration of interleukin-10-producing Type 1 regulatory cells in autoimmune diseases
Purpose of review This review highlights findings describing the role of interleukin (IL)-10-prod
Azacitidine maintenance in AML post induction and posttransplant
Azacitidine maintenance in AML post induction and posttransplant
Purpose of review Disease relapse remains the most common cause of death among patients with acut
Chimeric antigen receptor T-cell therapy in acute myeloid leukemia
Chimeric antigen receptor T-cell therapy in acute myeloid leukemia
Purpose of review Treatment outcome of relapsed or refractory AML patients remains dismal and new
Congenital neutropenia: disease models guiding new treatment strategies
Congenital neutropenia: disease models guiding new treatment strategies
Purpose of review Myeloid diseases are often characterized by a disturbed regulation of myeloid c
Hormetic endoplasmic reticulum stress in hematopoietic stem cells
Hormetic endoplasmic reticulum stress in hematopoietic stem cells
Purpose of review Hematopoietic stem cells (HSCs) possess the ability to regenerate over a lifeti
Recent lessons learned for ex-vivo platelet production
Recent lessons learned for ex-vivo platelet production
Purpose of review Platelet transfusion can be life-saving but carries a risk of infection or allo
Mechanisms of immunothrombosis in COVID-19
Mechanisms of immunothrombosis in COVID-19
Purpose of review Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe a
Detecting and preventing post-hematopoietic cell transplant relapse in AML
Detecting and preventing post-hematopoietic cell transplant relapse in AML
Purpose of review Relapsed disease is the primary cause of mortality for acute myeloid leukemia (