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Pathogenesis of Parkinson’s disease: from hints from monogenic familial PD to biomarkers
Pathogenesis of Parkinson’s disease: from hints from monogenic familial PD to biomarkers
Twenty-five years have passed since the causative gene for familial Parkinson's disease (PD), Parkin (now PRKN), was i...
Somatosensory evoked potentials recorded from DBS electrodes: the origin of subcortical N18
Somatosensory evoked potentials recorded from DBS electrodes: the origin of subcortical N18
The different peaks of somatosensory-evoked potentials (SEP) originate from a variety of anatomical sites in the central n...
Differential patterns of functional connectivity in tremor dominant Parkinson’s disease and essential tremor plus
Differential patterns of functional connectivity in tremor dominant Parkinson’s disease and essential tremor plus
Tremor dominant Parkinson’s disease (TDPD) and essential tremor plus (ETP) syndrome are commonly encountered tremor ...
Impaired dual-task gait in Parkinson’s disease is associated with brain morphology changes
Impaired dual-task gait in Parkinson’s disease is associated with brain morphology changes
In Parkinson’s disease (PD), impaired gait and cognition affect daily activities, particularly in the more advanced ...
Headache patterns in patent foramen ovale patients: beyond migraine with aura
Headache patterns in patent foramen ovale patients: beyond migraine with aura
Patent foramen ovale (PFO) is a common cardiac anomaly linked with cryptogenic strokes and migraine, particularly migraine...
NFKB1 variants were associated with the risk of Parkinson´s disease in male
NFKB1 variants were associated with the risk of Parkinson´s disease in male
The NF-κB pathway is involved in the pathogenesis of neurological disorders that have inflammation as a hallmark, inc...
More than fear? Brain activation patterns of dental phobic patients before and after an exposure-based treatment
More than fear? Brain activation patterns of dental phobic patients before and after an exposure-based treatment
Hyperactivation of brain networks conferring defensive mobilization is assumed to underlie inappropriate defensive-prepara...
It is not just about transcription: involvement of brain RNA splicing in substance use disorders
It is not just about transcription: involvement of brain RNA splicing in substance use disorders
Alternative splicing is a co-transcriptional process that significantly contributes to the molecular landscape of the cell...
Combined light and electron microscopy (CLEM) to quantify methamphetamine-induced alpha-synuclein-related pathology
Combined light and electron microscopy (CLEM) to quantify methamphetamine-induced alpha-synuclein-related pathology
Methamphetamine (METH) produces a cytopathology, which is rather specific within catecholamine neurons both in vitro and e...
Edema related to treatment with psychotropic drugs
Edema related to treatment with psychotropic drugs
Edema as an adverse drug reaction is a commonly underestimated yet potentially debilitating condition. This study analyzes...
Obsessive–compulsive symptoms and brain lesions compatible with multiple sclerosis
Obsessive–compulsive symptoms and brain lesions compatible with multiple sclerosis
Autoimmune-mediated obsessive–compulsive disorder (OCD) can occur in multiple sclerosis (MS). Here, a well-studied c...
Validation of the Italian version of the Parkinson’s Disease- Cognitive Functional Rating Scale
Validation of the Italian version of the Parkinson’s Disease- Cognitive Functional Rating Scale
A key distinguishing factor between mild cognitive impairment (MCI) and dementia in Parkinson’s disease (PD) lies in...
Virus-induced brain pathology and the neuroinflammation-inflammation continuum: the neurochemists view
Virus-induced brain pathology and the neuroinflammation-inflammation continuum: the neurochemists view
Fascinatingly, an abundance of recent studies has subscribed to the importance of cytotoxic immune mechanisms that appear ...
Mild cognitive impairment in Huntington’s disease: challenges and outlooks
Mild cognitive impairment in Huntington’s disease: challenges and outlooks
Although Huntington's disease (HD) has classically been viewed as an autosomal-dominant inherited neurodegenerative mo...
Association between autonomic dysfunction with motor and non-motor symptoms in patients with Parkinson's disease
Association between autonomic dysfunction with motor and non-motor symptoms in patients with Parkinson's disease
To investigate the association between autonomic dysfunction (AutD) and motor as well as non-motor symptoms (NMS) in patie...
Modulatory effect of olanzapine on neuronal nitric oxide synthase (nNOS) expression in the rat striatum
Modulatory effect of olanzapine on neuronal nitric oxide synthase (nNOS) expression in the rat striatum
Nitric oxide (NO) has been thought to be a novel factor involved in the mechanisms of mental disorders pathogenesis for qu...
Functional AGXT2 SNP rs180749 variant and depressive symptoms: Baseline data from the Aidai Cohort Study in Japan
Functional AGXT2 SNP rs180749 variant and depressive symptoms: Baseline data from the Aidai Cohort Study in Japan
No study has shown the relationship between alanine-glyoxylate aminotransferase 2 (AGXT2) single nucleotide polymorphisms ...
The natural course of idiopathic cervical dystonia
The natural course of idiopathic cervical dystonia
Idiopathic cervical dystonia (ICD) is by far the largest subgroup of dystonia. Still, its natural course is largely unknow...
Driving innovation in addiction treatment: role of transcranial magnetic stimulation
Driving innovation in addiction treatment: role of transcranial magnetic stimulation
Addictions comprises heterogenous psychiatric conditions caused by the complex interaction of genetic, neurobiological, ps...
Constipation and pain in Parkinson’s disease: a clinical analysis
Constipation and pain in Parkinson’s disease: a clinical analysis
Parkinson’s Disease (PD) is a neurodegenerative disorder characterized by both motor and non-motor symptoms (NMS). A...
Morphometric alterations of the mesocorticolimbic network in Parkinson’s disease with impulse control disorders
Morphometric alterations of the mesocorticolimbic network in Parkinson’s disease with impulse control disorders
Impulse control disorders (ICDs) are a group of non-motor symptoms of Parkinson disease (PD) leading to significant psycho...
The enigma of depression in corticobasal degeneration, a frequent but poorly understood co-morbidity
The enigma of depression in corticobasal degeneration, a frequent but poorly understood co-morbidity
Depression is one of the most frequent neuropsychiatric symptoms in corticobasal degeneration (CBD), a rare, sporadic, and...
Current perspectives on brain circuits involved in food addiction-like behaviors
Current perspectives on brain circuits involved in food addiction-like behaviors
There is an emerging view that the increased availability of energy-dense foods in our society is contributing to excessiv...
Facial emotion recognition deficits are associated with hypomimia and related brain correlates in Parkinson’s disease
Facial emotion recognition deficits are associated with hypomimia and related brain correlates in Parkinson’s disease
Hypomimia is a frequent manifestation in Parkinson's disease (PD) that can affect interpersonal relationships and qual...