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The relationship between uric acid levels, cognition and inflammation in a cohort of elderly subjects
The relationship between uric acid levels, cognition and inflammation in a cohort of elderly subjects
Uric acid (UA) is the most powerful antioxidant found among human body fluids. With this effect, UA protects neurons from ...
Sex-dependent associations of serum BDNF, glycolipid metabolism and cognitive impairments in Parkinson’s disease with depression: a comprehensive analysis
Sex-dependent associations of serum BDNF, glycolipid metabolism and cognitive impairments in Parkinson’s disease with depression: a comprehensive analysis
Brain-derived neurotrophic factor (BDNF) and glycolipid metabolism have been implicated in cognitive impairments and depre...
Cognition and Activity of Daily Living Function in people with Parkinson’s disease
Cognition and Activity of Daily Living Function in people with Parkinson’s disease
The ability to perform activities of daily living (ADL) function is a multifaceted construct that reflects functionality i...
Grasping the big picture: impact analysis of screening tools for timely referral for device-aided therapies
Grasping the big picture: impact analysis of screening tools for timely referral for device-aided therapies
Several screening tools are available to assist general neurologists in the timely identification of patients with advance...
Therapeutic potential of transient receptor potential (TRP) channels in psychiatric disorders
Therapeutic potential of transient receptor potential (TRP) channels in psychiatric disorders
Psychiatric disorders such as Bipolar disorder, Anxiety, Major depressive disorder, Schizophrenia, Attention-deficit/hyper...
The neural structures of theory of mind are valence-sensitive: evidence from three tDCS studies
The neural structures of theory of mind are valence-sensitive: evidence from three tDCS studies
Several cortical structures are involved in theory of mind (ToM), including the dorsolateral prefrontal cortex (dlPFC), th...
Differential diagnosis of Huntington’s disease− neurological aspects of NKX2-1-related disorders
Differential diagnosis of Huntington’s disease− neurological aspects of NKX2-1-related disorders
Benign hereditary chorea (BHC) is an inherited neurological disorder consisting of childhood-onset, nonprogressive chorea,...
Risk of Parkinson’s disease in hepatitis B and C populations: a systematic review and meta-analysis
Risk of Parkinson’s disease in hepatitis B and C populations: a systematic review and meta-analysis
Parkinson’s disease (PD) is a common neurodegenerative disorder, and its association with viral hepatitis has been d...
From parents to children: associations of traffic risks with impulsivity, family relationships and serotonin transporter genotype
From parents to children: associations of traffic risks with impulsivity, family relationships and serotonin transporter genotype
Road traffic injuries are the leading cause of death for young adults, and parents play a major role in shaping their traf...
In situ stoichiometry amounts of p62 and poly-ubiquitin exceed the increase of alpha-synuclein during degeneration of catecholamine cells induced by autophagy inhibition in vitro
In situ stoichiometry amounts of p62 and poly-ubiquitin exceed the increase of alpha-synuclein during degeneration of catecholamine cells induced by autophagy inhibition in vitro
Neurodegenerative disorders are typically featured by the occurrence of neuronal inclusions. In the case of Parkinson̵...
Alterations in metabolites in the anterior cingulate cortex and thalamus and their associations with pain and empathy in patients with chronic mild pain: a preliminary study
Alterations in metabolites in the anterior cingulate cortex and thalamus and their associations with pain and empathy in patients with chronic mild pain: a preliminary study
Proton magnetic resonance spectroscopy (1H-MRS) has shown inconsistent alterations in the brain metabolites of individuals...
Effects of association between resveratrol and ketamine on behavioral and biochemical analysis in mice
Effects of association between resveratrol and ketamine on behavioral and biochemical analysis in mice
Resveratrol (3,5,4′-trihydroxy-trans-stilbene), a phenol commonly found in grapes and wine, has been associated as p...
Pathological mechanisms and treatment of sporadic Parkinson’s disease: past, present, and future
Pathological mechanisms and treatment of sporadic Parkinson’s disease: past, present, and future
For a special issue, we review studies on the pathogenesis of nigral cell death and the treatment of sporadic Parkinson...
Depression and anxiety in multiple sclerosis. Review of a fatal combination
Depression and anxiety in multiple sclerosis. Review of a fatal combination
Depression and anxiety are the most frequent neuropsychiatric symptoms of multiple sclerosis (MS), an autoimmune-mediated ...
Does botulinum toxin affect psycho-social aspects in dystonia?
Does botulinum toxin affect psycho-social aspects in dystonia?
Dystonia is a movement disorder in which sustained muscle contractions give rise to abnormal postures or involuntary movem...
Increased levels of regulatory T cells and IL-10-producing regulatory B cells are linked to improved clinical outcome in Parkinson’s disease: a 1-year observational study
Increased levels of regulatory T cells and IL-10-producing regulatory B cells are linked to improved clinical outcome in Parkinson’s disease: a 1-year observational study
Whilst the contribution of peripheral and central inflammation to neurodegeneration in Parkinson’s disease and the r...
Possible improvement of social adjustment after subthalamic deep brain stimulation in people with Parkinson’s disease? A systematic review and meta-analysis
Possible improvement of social adjustment after subthalamic deep brain stimulation in people with Parkinson’s disease? A systematic review and meta-analysis
Interactions with others need social adjustment (i.e., the constant accommodation to changing social situations). Mixed ev...
Cognitive impairment in multiple sclerosis: from phenomenology to neurobiological mechanisms
Cognitive impairment in multiple sclerosis: from phenomenology to neurobiological mechanisms
Multiple sclerosis (MS) is an autoimmune-mediated disease of the central nervous system characterized by inflammation, dem...
Clinical and kinematic characterization of parkinsonian soft signs in essential tremor
Clinical and kinematic characterization of parkinsonian soft signs in essential tremor
Subtle parkinsonian signs, i.e., rest tremor and bradykinesia, are considered soft signs for defining essential tremor (ET...
Sex differences and risk factors of self-reported suicide attempts in middle-aged Chinese Han patients with first-episode drug-naïve anxious depression: a large-scale cross-sectional study
Sex differences and risk factors of self-reported suicide attempts in middle-aged Chinese Han patients with first-episode drug-naïve anxious depression: a large-scale cross-sectional study
This study aims to investigate sex differences and risk factors for self-reported suicide attempts among Chinese Han middl...
What was first and what is next in selecting device-aided therapy in Parkinson’s disease? Balancing evidence and experience
What was first and what is next in selecting device-aided therapy in Parkinson’s disease? Balancing evidence and experience
Parkinson’s disease (PD) progresses with motor fluctuations emerging several years after treatment initiation. Initi...
The influence of gender-specific factors influencing severe anxiety in psychotic major depression: role of thyroid hormones and depression severity
The influence of gender-specific factors influencing severe anxiety in psychotic major depression: role of thyroid hormones and depression severity
Psychotic major depression (PMD) is characterized by major depressive disorder (MDD) accompanied by delusions or hallucina...
Altered domain-specific striatal functional connectivity in patients with Parkinson’s disease and urinary symptoms
Altered domain-specific striatal functional connectivity in patients with Parkinson’s disease and urinary symptoms
In this study, we aimed at investigating the possible association of urinary symptoms with whole-brain MRI resting-state f...
The impact of transcranial direct current stimulation on attention bias modification in children with ADHD
The impact of transcranial direct current stimulation on attention bias modification in children with ADHD
Individuals with attention deficit-hyperactivity disorder (ADHD) struggle with the interaction of attention and emotion. T...
RNA sequencing of the thalamus and rostral ventral medulla in rats with chronic orofacial pain
RNA sequencing of the thalamus and rostral ventral medulla in rats with chronic orofacial pain
Diagnosing and treating chronic orofacial pain is challenging due to its complex structure and limited understanding of it...
Neuromarkers in addiction: definitions, development strategies, and recent advances
Neuromarkers in addiction: definitions, development strategies, and recent advances
Substance use disorders (SUDs) are the most costly and prevalent psychiatric conditions. Recent calls emphasize a need for...
Paradoxical effect of anti-inflammatory drugs on IL-6 mRNA expression in patients with PTSD during treatment
Paradoxical effect of anti-inflammatory drugs on IL-6 mRNA expression in patients with PTSD during treatment
The pathophysiology of posttraumatic stress disorder (PTSD) is associated with the activation of the innate immune system,...
Advanced therapies in Parkinson’s disease: an individualized approach to their indication
Advanced therapies in Parkinson’s disease: an individualized approach to their indication
Device aided therapies (DAT) comprising the intrajejunal administration of levodopa/carbidopa intestinal gel (LCIG) and le...
Beam narrowing test: a motor index of post-stroke motor evaluation in an aged rat model of cerebral ischemia
Beam narrowing test: a motor index of post-stroke motor evaluation in an aged rat model of cerebral ischemia
Each year, 15 million people worldwide suffer from strokes. Consequently, researchers face increasing pressure to develop ...
Parkinson's disease and vitamins: a focus on vitamin B12
Parkinson's disease and vitamins: a focus on vitamin B12
Parkinson’s disease (PD) has been linked to a vast array of vitamins among which vitamin B12 (Vit B12) is the most r...
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