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Discrimination of Baphicacanthis Cusiae Rhizoma et radix and its adulterant species and establishment of an assay method for quality control
Discrimination of Baphicacanthis Cusiae Rhizoma et radix and its adulterant species and establishment of an assay method for quality control
Baphicacanthis Cusiae Rhizoma et Radix, commonly known as Nan-Ban-Lan-Gen (NBLG), is an essential traditional Chinese medi...
Expanding potential targets of herbal chemicals by node2vec based on herb–drug interactions
Expanding potential targets of herbal chemicals by node2vec based on herb–drug interactions
The identification of chemical–target interaction is key to pharmaceutical research and development, but the unclear...
Citrus alkaline extracts improve LPS-induced pulmonary fibrosis via epithelial mesenchymal transition signals
Citrus alkaline extracts improve LPS-induced pulmonary fibrosis via epithelial mesenchymal transition signals
Acute respiratory distress syndrome (ARDS) is a serious life threatening clinical critical illness. ARDS-related pulmonary...
UPLC-QTOF-MS with a chemical profiling approach for holistic quality evaluation between a material reference of Wen Dan decoction and its commercial preparations
UPLC-QTOF-MS with a chemical profiling approach for holistic quality evaluation between a material reference of Wen Dan decoction and its commercial preparations
Wen Dan decoction (WDD) has been a famous classic formula for resolving phlegm since ancient times in China. Currently, th...
Pulsatilla Decoction and its bioactive component β-peltatin induce G2/M cell cycle arrest and apoptosis in pancreatic cancer
Pulsatilla Decoction and its bioactive component β-peltatin induce G2/M cell cycle arrest and apoptosis in pancreatic cancer
Pancreatic cancer (PAC), a malignancy that is fatal and commonly diagnosed at a late stage. Despite considerable advanceme...
TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea
TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea
Pulmonary fibrosis (PF) is a chronic and potentially fatal lung disease and disorder. Although the active ingredients of g...
Systematic analysis of randomised controlled trials of Chinese herb medicine for non-alcoholic steatohepatitis (NASH): implications for future drug development and trial design
Systematic analysis of randomised controlled trials of Chinese herb medicine for non-alcoholic steatohepatitis (NASH): implications for future drug development and trial design
Non-alcoholic steatohepatitis (NASH) is a liver disease currently lacking an approved therapy, resulting in significant cl...
Traditional Chinese medicine in the era of immune checkpoint inhibitor: theory, development, and future directions
Traditional Chinese medicine in the era of immune checkpoint inhibitor: theory, development, and future directions
Immune checkpoint inhibitors (ICIs) have revolutionized cancer management and have been widely applied; however, they stil...
Identification of the Main Chemical constituents and mechanism of Renshen Guben oral liquid against Renal Fibrosis
Identification of the Main Chemical constituents and mechanism of Renshen Guben oral liquid against Renal Fibrosis
Renal fibrosis is the late stage of many chronic kidney diseases (CKD). Clinically, there is almost no effective treatment...
Therapeutic mechanisms of the medicine and food homology formula Xiao-Ke-Yin on glucolipid metabolic dysfunction revealed by transcriptomics, metabolomics and microbiomics in mice
Therapeutic mechanisms of the medicine and food homology formula Xiao-Ke-Yin on glucolipid metabolic dysfunction revealed by transcriptomics, metabolomics and microbiomics in mice
In recent decades, the prevalence of metabolic diseases, particularly diabetes, hyperlipidemia, obesity, and non-alcoholic...
Correction: Shengjiang San alleviated sepsis-induced lung injury through its bidirectional regulatory effect
Correction: Shengjiang San alleviated sepsis-induced lung injury through its bidirectional regulatory effect
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whic...
Tanshinone IIA inhibits osteoclastogenesis in rheumatoid arthritis via LDHC-regulated ROS generation
Tanshinone IIA inhibits osteoclastogenesis in rheumatoid arthritis via LDHC-regulated ROS generation
Rheumatoid arthritis (RA) is characterized by bone destruction in the afflicted joints, and during the process of bone des...
The relationship between gut microbiota and susceptibility to type 2 diabetes mellitus in rats
The relationship between gut microbiota and susceptibility to type 2 diabetes mellitus in rats
The purpose of this study is to investigate the relationship between the susceptibility to type 2 diabetes and gut microbi...
Panax notoginseng saponins inhibits NLRP3 inflammasome-mediated pyroptosis by downregulating lncRNA-ANRIL in cardiorenal syndrome type 4
Panax notoginseng saponins inhibits NLRP3 inflammasome-mediated pyroptosis by downregulating lncRNA-ANRIL in cardiorenal syndrome type 4
Cardiorenal syndrome type 4 (CRS4) is a complication of chronic kidney disease. Panax notoginseng saponins (PNS) have been...
Cyp4a12-mediated retinol metabolism in stellate cells is the antihepatic fibrosis mechanism of the Chinese medicine Fuzheng Huayu recipe
Cyp4a12-mediated retinol metabolism in stellate cells is the antihepatic fibrosis mechanism of the Chinese medicine Fuzheng Huayu recipe
Hepatic stellate cells (HSCs), which contain multiple retinol-containing lipid droplets, are important profibrotic cells i...
Bushen-Yizhi formula ameliorates mitochondrial dysfunction and oxidative stress via AMPK/Sirt1 signaling pathway in D-gal-induced aging rats
Bushen-Yizhi formula ameliorates mitochondrial dysfunction and oxidative stress via AMPK/Sirt1 signaling pathway in D-gal-induced aging rats
As a major risk factor for neurodegenerative diseases, aging has become a heavy health care burden worldwide. Age-related ...
Exploring the effect of Yinzhihuang granules on alcoholic liver disease based on pharmacodynamics, network pharmacology and molecular docking
Exploring the effect of Yinzhihuang granules on alcoholic liver disease based on pharmacodynamics, network pharmacology and molecular docking
Yinzhihuang granules (YZHG) is a commonly used Chinese patent medicine for the treatment of liver disease. However, the me...
A clinical experience-based Chinese herbal formula improves ethanol-induced drunken behavior and hepatic steatohepatitis in mice models
A clinical experience-based Chinese herbal formula improves ethanol-induced drunken behavior and hepatic steatohepatitis in mice models
Bao-Gan-Xing-Jiu-Wan (BGXJW) is a clinical experience-based Chinese herbal formula. Its efficacy, pharmacological safety, ...
Study on basic and clinical application of Shufeng Jiedu Capsule in treating respiratory tract infection
Study on basic and clinical application of Shufeng Jiedu Capsule in treating respiratory tract infection
Shufeng Jiedu Capsule (SFJDC), composed of eight herbs, is a big brand traditional Chinese medicine (TCM) for the treatmen...
Gegen Qinlian standard decoction alleviated irinotecan-induced diarrhea via PI3K/AKT/NF-κB axis by network pharmacology prediction and experimental validation combination
Gegen Qinlian standard decoction alleviated irinotecan-induced diarrhea via PI3K/AKT/NF-κB axis by network pharmacology prediction and experimental validation combination
The frequently occurred chemotherapy-induced diarrhea (CID) caused by irinotecan (CPT-11) administration has been the most...
Exploring the mechanism of Taohong Siwu Decoction on the treatment of blood deficiency and blood stasis syndrome by gut microbiota combined with metabolomics
Exploring the mechanism of Taohong Siwu Decoction on the treatment of blood deficiency and blood stasis syndrome by gut microbiota combined with metabolomics
Taohong Siwu Decoction (THSWD) is a prescription which included in the “List of Ancient Classic Prescriptions (First...
Monotropein attenuates apoptosis and pyroptosis in chondrocytes and alleviates osteoarthritis progression in mice
Monotropein attenuates apoptosis and pyroptosis in chondrocytes and alleviates osteoarthritis progression in mice
Osteoarthritis (OA) is a chronic degenerative joint disease characterized by loss of joint function, which seriously reduc...
Machine learning in TCM with natural products and molecules: current status and future perspectives
Machine learning in TCM with natural products and molecules: current status and future perspectives
Traditional Chinese medicine (TCM) has been practiced for thousands of years with clinical efficacy. Natural products and ...
Berberine improves negative symptoms and cognitive function in patients with chronic schizophrenia via anti-inflammatory effect: a randomized clinical trial
Berberine improves negative symptoms and cognitive function in patients with chronic schizophrenia via anti-inflammatory effect: a randomized clinical trial
Based on the neuroinflammation hypothesis in schizophrenia and known anti-inflammatory effects of berberine, the aim of th...
Shengjiang San alleviated sepsis-induced lung injury through its bidirectional regulatory effect
Shengjiang San alleviated sepsis-induced lung injury through its bidirectional regulatory effect
Sepsis is a life-threatening organ dysfunction caused by dysregulated host responses to infection, for which effective the...
A novel microbial and hepatic biotransformation-integrated network pharmacology strategy explores the therapeutic mechanisms of bioactive herbal products in neurological diseases: the effects of Astragaloside IV on intracerebral hemorrhage as an example
A novel microbial and hepatic biotransformation-integrated network pharmacology strategy explores the therapeutic mechanisms of bioactive herbal products in neurological diseases: the effects of Astragaloside IV on intracerebral hemorrhage as an example
The oral bioavailability and blood–brain barrier permeability of many herbal products are too low to explain the sig...
Adverse effects associated with acupuncture therapies: An evidence mapping from 535 systematic reviews
Adverse effects associated with acupuncture therapies: An evidence mapping from 535 systematic reviews
Considering that physicians and patients widely use acupuncture, it is necessary to explore its adverse effects during tre...
Association of lung-intestinal microecology and lung cancer therapy
Association of lung-intestinal microecology and lung cancer therapy
In recent years, the incidence of lung cancer is increasing. Lung cancer has become one of the most malignant tumors with ...
Aqueous extract of Platycodon grandiflorus attenuates lipopolysaccharide-induced apoptosis and inflammatory cell infiltration in mouse lungs by inhibiting PI3K/Akt signaling
Aqueous extract of Platycodon grandiflorus attenuates lipopolysaccharide-induced apoptosis and inflammatory cell infiltration in mouse lungs by inhibiting PI3K/Akt signaling
Acute lung injury (ALI), an acute inflammatory lung disease, can cause a rapid inflammatory response in clinic, which enda...
Psoralidin inhibits osteosarcoma growth and metastasis by downregulating ITGB1 expression via the FAK and PI3K/Akt signaling pathways
Psoralidin inhibits osteosarcoma growth and metastasis by downregulating ITGB1 expression via the FAK and PI3K/Akt signaling pathways
Psoralea corylifolia is a medicinal leguminous plant that has long been used to treat various diseases. Psoralidin (PSO) i...
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