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Nrf2 mediates the effects of shionone on silica-induced pulmonary fibrosis
Nrf2 mediates the effects of shionone on silica-induced pulmonary fibrosis
Extended contact with silica particles can lead to Silicosis, a chronic lung condition lacking established treatment proto...
Shaoyao Decoction reduced T lymphocyte activation by regulating of intestinal flora and 5-hydroxytryptamine metabolism in ulcerative colitis
Shaoyao Decoction reduced T lymphocyte activation by regulating of intestinal flora and 5-hydroxytryptamine metabolism in ulcerative colitis
Shaoyao Decoction (SYD) is a widely recognized herbal formula utilized in traditional Chinese medicine for the treatment o...
β-elemene promotes microglial M2-like polarization against ischemic stroke via AKT/mTOR signaling axis-mediated autophagy
β-elemene promotes microglial M2-like polarization against ischemic stroke via AKT/mTOR signaling axis-mediated autophagy
Resident microglia- and peripheric macrophage-mediated neuroinflammation plays a predominant role in the occurrence and de...
Improvement effects of a novel Chinese herbal formula in imiquimod and IL-23-stimulated mouse models of psoriasis
Improvement effects of a novel Chinese herbal formula in imiquimod and IL-23-stimulated mouse models of psoriasis
Psoriasis is a long-term inflammatory skin disease. A novel herbal formula containing nine Chinese herbal medicines, named...
Lab-on-a-chip: an advanced technology for the modernization of traditional Chinese medicine
Lab-on-a-chip: an advanced technology for the modernization of traditional Chinese medicine
Benefiting from the complex system composed of various constituents, medicament portions, species, and places of origin, t...
Xinbao Pill ameliorates heart failure via regulating the SGLT1/AMPK/PPARα axis to improve myocardial fatty acid energy metabolism
Xinbao Pill ameliorates heart failure via regulating the SGLT1/AMPK/PPARα axis to improve myocardial fatty acid energy metabolism
Heart failure (HF) is characterized by a disorder of cardiomyocyte energy metabolism. Xinbao Pill (XBW), a traditional Chi...
The effect of modified Qiyuan paste on mice with low immunity and sleep deprivation by regulating GABA nerve and immune system
The effect of modified Qiyuan paste on mice with low immunity and sleep deprivation by regulating GABA nerve and immune system
Low immunity and sleep disorders are prevalent suboptimal health conditions in contemporary populations, which render them...
Saiga antelope horn suppresses febrile seizures in rats by regulating neurotransmitters and the arachidonic acid pathway
Saiga antelope horn suppresses febrile seizures in rats by regulating neurotransmitters and the arachidonic acid pathway
Saiga antelope horn (SAH) is a traditional Chinese medicine for treating febrile seizure (FS) with precise efficacy, but i...
Traditional Chinese Medicine and renal regeneration: experimental evidence and future perspectives
Traditional Chinese Medicine and renal regeneration: experimental evidence and future perspectives
Repair of acute kidney injury (AKI) is a typical example of renal regeneration. AKI is characterized by tubular cell death...
Oleanolic acid and its analogues: promising therapeutics for kidney disease
Oleanolic acid and its analogues: promising therapeutics for kidney disease
Kidney diseases pose a significant threat to human health due to their high prevalence and mortality rates. Worryingly, th...
Natural L-type calcium channels antagonists from Chinese medicine
Natural L-type calcium channels antagonists from Chinese medicine
L-type calcium channels (LTCCs), the largest subfamily of voltage-gated calcium channels (VGCCs), are the main channels fo...
Development of an interpretable machine learning model associated with genetic indicators to identify Yin-deficiency constitution
Development of an interpretable machine learning model associated with genetic indicators to identify Yin-deficiency constitution
Traditional Chinese Medicine (TCM) defines constitutions which are relevant to corresponding diseases among people. As one...
Cirsilineol inhibits RANKL-induced osteoclast activity and ovariectomy-induced bone loss via NF-κb/ERK/p38 signaling pathways
Cirsilineol inhibits RANKL-induced osteoclast activity and ovariectomy-induced bone loss via NF-κb/ERK/p38 signaling pathways
Postmenopausal osteoporosis is a chronic metabolic bone disease caused by excessive osteoclast formation and function. Tar...
Acacetin alleviates autoimmune myocarditis by regulating CD4+ T cell mitochondrial respiration
Acacetin alleviates autoimmune myocarditis by regulating CD4+ T cell mitochondrial respiration
Myocarditis refers to an autoimmune inflammatory response of the myocardium with characterization of self-reactive CD4+...
Traditional uses, phytochemistry, pharmacology, quality control and clinical studies of Cimicifugae Rhizoma: a comprehensive review
Traditional uses, phytochemistry, pharmacology, quality control and clinical studies of Cimicifugae Rhizoma: a comprehensive review
Cimicifugae Rhizoma, generally known as “Sheng Ma” in China, has great medicinal and dietary values. Cimicifug...
“Qi Nan” agarwood restores podocyte autophagy in diabetic kidney disease by targeting EGFR signaling pathway
“Qi Nan” agarwood restores podocyte autophagy in diabetic kidney disease by targeting EGFR signaling pathway
Diabetic kidney disease (DKD) is a microvascular complication of diabetes mellitus, contributing to end-stage renal diseas...
Metabolite identification of salvianolic acid A in rat using post collision-induced dissociation energy-resolved mass spectrometry
Metabolite identification of salvianolic acid A in rat using post collision-induced dissociation energy-resolved mass spectrometry
As one of the most famous natural products, salvianolic acid A (SAA) is undergoing clinical trials for the treatments of a...
Compound Shenma Jingfu granule alleviates cerebral ischemia via HIF-1α-mediated promotion of angiogenesis
Compound Shenma Jingfu granule alleviates cerebral ischemia via HIF-1α-mediated promotion of angiogenesis
Shenma Jingfu Granule, a traditional Chinese medicine formula, has been used clinically for the treatment of cerebral circ...
NBR1-p62-Nrf2 mediates the anti-pulmonary fibrosis effects of protodioscin
NBR1-p62-Nrf2 mediates the anti-pulmonary fibrosis effects of protodioscin
Idiopathic pulmonary fibrosis is a persistent disease of the lung interstitium for which there is no efficacious pharmacol...