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Deciphering the benefits and intensity levels of primary metabolites from Allium macrostemon Bunge and Allium chinense G. Don
Deciphering the benefits and intensity levels of primary metabolites from Allium macrostemon Bunge and Allium chinense G. Don
Allii Macrostemonis Bulbus is also named Xiebai in China. It is an edible vegetable, and also a famous herb for treating c...
Santalum album L. alleviates cardiac function injury in heart failure by synergistically inhibiting inflammation, oxidative stress and apoptosis through multiple components
Santalum album L. alleviates cardiac function injury in heart failure by synergistically inhibiting inflammation, oxidative stress and apoptosis through multiple components
Heart failure (HF) is a complex cardiovascular syndrome with high mortality. Santalum album L. (SAL) is a traditional Chin...
Theoretical exploring of potential mechanisms of antithrombotic ingredients in danshen-chishao herb-pair by network pharmacological study, molecular docking and zebrafish models
Theoretical exploring of potential mechanisms of antithrombotic ingredients in danshen-chishao herb-pair by network pharmacological study, molecular docking and zebrafish models
Salvia miltiorrhiza (Danshen, DS) and Radix Paeoniae Rubra (Chishao, CS) herbal pair (DS-CS) is a famous traditional Chine...
Rhei Undulati Rhizoma attenuates memory decline and reduces amyloid-β induced neuritic dystrophy in 5xFAD mouse
Rhei Undulati Rhizoma attenuates memory decline and reduces amyloid-β induced neuritic dystrophy in 5xFAD mouse
Alzheimer's disease (AD) is a common type of dementia characterized by amyloid-β (Aβ) accumulation, lysosoma...
Application of 3D bioprinting technology apply to assessing Dangguiniantongtang (DGNT) decoctions in arthritis
Application of 3D bioprinting technology apply to assessing Dangguiniantongtang (DGNT) decoctions in arthritis
The aim of this study was to develop a three-dimensional (3D) cell model in order to evaluate the effectiveness of a tradi...
Pharmacological activity and clinical application analysis of traditional Chinese medicine ginger from the perspective of one source and multiple substances
Pharmacological activity and clinical application analysis of traditional Chinese medicine ginger from the perspective of one source and multiple substances
All types of ginger have common fundamental components, although they possess distinct strengths and inclinations when it ...
Phytotherapeutic potential against MRSA: mechanisms, synergy, and therapeutic prospects
Phytotherapeutic potential against MRSA: mechanisms, synergy, and therapeutic prospects
Rising resistance to antimicrobials, particularly in the case of methicillin-resistant Staphylococcus aureus (MRSA), repre...
Nrf2 mediates the effects of shionone on silica-induced pulmonary fibrosis
Nrf2 mediates the effects of shionone on silica-induced pulmonary fibrosis
Extended contact with silica particles can lead to Silicosis, a chronic lung condition lacking established treatment proto...
Shaoyao Decoction reduced T lymphocyte activation by regulating of intestinal flora and 5-hydroxytryptamine metabolism in ulcerative colitis
Shaoyao Decoction reduced T lymphocyte activation by regulating of intestinal flora and 5-hydroxytryptamine metabolism in ulcerative colitis
Shaoyao Decoction (SYD) is a widely recognized herbal formula utilized in traditional Chinese medicine for the treatment o...
β-elemene promotes microglial M2-like polarization against ischemic stroke via AKT/mTOR signaling axis-mediated autophagy
β-elemene promotes microglial M2-like polarization against ischemic stroke via AKT/mTOR signaling axis-mediated autophagy
Resident microglia- and peripheric macrophage-mediated neuroinflammation plays a predominant role in the occurrence and de...
Improvement effects of a novel Chinese herbal formula in imiquimod and IL-23-stimulated mouse models of psoriasis
Improvement effects of a novel Chinese herbal formula in imiquimod and IL-23-stimulated mouse models of psoriasis
Psoriasis is a long-term inflammatory skin disease. A novel herbal formula containing nine Chinese herbal medicines, named...
Liguzinediol potentiates the metabolic remodeling by activating the AMPK/SIRT3 pathway and represses Caspase-3/GSDME-mediated pyroptosis to ameliorate cardiotoxicity
Liguzinediol potentiates the metabolic remodeling by activating the AMPK/SIRT3 pathway and represses Caspase-3/GSDME-mediated pyroptosis to ameliorate cardiotoxicity
Liguzinediol (Lig) has emerged as a promising candidate for mitigating Doxorubicin (DOX)-induced cardiotoxicity, a signifi...
Lab-on-a-chip: an advanced technology for the modernization of traditional Chinese medicine
Lab-on-a-chip: an advanced technology for the modernization of traditional Chinese medicine
Benefiting from the complex system composed of various constituents, medicament portions, species, and places of origin, t...
Zedoary turmeric oil injection ameliorates lung inflammation via platelet factor 4 and regulates gut microbiota disorder in respiratory syncytial virus-infected young mice
Zedoary turmeric oil injection ameliorates lung inflammation via platelet factor 4 and regulates gut microbiota disorder in respiratory syncytial virus-infected young mice
Respiratory syncytial virus (RSV)-induced lung inflammation is one of the main causes of hospitalization and easily causes...
Xinbao Pill ameliorates heart failure via regulating the SGLT1/AMPK/PPARα axis to improve myocardial fatty acid energy metabolism
Xinbao Pill ameliorates heart failure via regulating the SGLT1/AMPK/PPARα axis to improve myocardial fatty acid energy metabolism
Heart failure (HF) is characterized by a disorder of cardiomyocyte energy metabolism. Xinbao Pill (XBW), a traditional Chi...
The effect of modified Qiyuan paste on mice with low immunity and sleep deprivation by regulating GABA nerve and immune system
The effect of modified Qiyuan paste on mice with low immunity and sleep deprivation by regulating GABA nerve and immune system
Low immunity and sleep disorders are prevalent suboptimal health conditions in contemporary populations, which render them...
Si-Wu-Tang alleviates metabolic dysfunction-associated fatty liver disease by inhibiting ACSL4-mediated arachidonic acid metabolism and ferroptosis in MCD diet-fed mice
Si-Wu-Tang alleviates metabolic dysfunction-associated fatty liver disease by inhibiting ACSL4-mediated arachidonic acid metabolism and ferroptosis in MCD diet-fed mice
Metabolic dysfunction-associated fatty liver disease (MAFLD) is a prevalent chronic liver disease worldwide. Si-Wu-Tang (S...
Saiga antelope horn suppresses febrile seizures in rats by regulating neurotransmitters and the arachidonic acid pathway
Saiga antelope horn suppresses febrile seizures in rats by regulating neurotransmitters and the arachidonic acid pathway
Saiga antelope horn (SAH) is a traditional Chinese medicine for treating febrile seizure (FS) with precise efficacy, but i...
Chrysanthemum morifolium Ramat extract and probiotics combination ameliorates metabolic disorders through regulating gut microbiota and PPARα subcellular localization
Chrysanthemum morifolium Ramat extract and probiotics combination ameliorates metabolic disorders through regulating gut microbiota and PPARα subcellular localization
Chrysanthemum morifolium Ramat, a traditional Chinese medicine, has the effects on liver clearing, vision improving, and a...
Traditional Chinese Medicine and renal regeneration: experimental evidence and future perspectives
Traditional Chinese Medicine and renal regeneration: experimental evidence and future perspectives
Repair of acute kidney injury (AKI) is a typical example of renal regeneration. AKI is characterized by tubular cell death...
A simplified herbal decoction attenuates myocardial infarction by regulating macrophage metabolic reprogramming and phenotypic differentiation via modulation of the HIF-1α/PDK1 axis
A simplified herbal decoction attenuates myocardial infarction by regulating macrophage metabolic reprogramming and phenotypic differentiation via modulation of the HIF-1α/PDK1 axis
Myocardial infarction (MI) poses a global public health challenge, often associated with elevated mortality rates and a gr...
Oleanolic acid and its analogues: promising therapeutics for kidney disease
Oleanolic acid and its analogues: promising therapeutics for kidney disease
Kidney diseases pose a significant threat to human health due to their high prevalence and mortality rates. Worryingly, th...
An-Gong-Niu-Huang-Wan (AGNHW) regulates cerebral blood flow by improving hypoperfusion, cerebrovascular reactivity and microcirculation disturbances after stroke
An-Gong-Niu-Huang-Wan (AGNHW) regulates cerebral blood flow by improving hypoperfusion, cerebrovascular reactivity and microcirculation disturbances after stroke
The restoration of cerebrovascular regulation and improvement of cerebral blood flow in ischaemic regions are crucial for ...
Natural L-type calcium channels antagonists from Chinese medicine
Natural L-type calcium channels antagonists from Chinese medicine
L-type calcium channels (LTCCs), the largest subfamily of voltage-gated calcium channels (VGCCs), are the main channels fo...
Development of an interpretable machine learning model associated with genetic indicators to identify Yin-deficiency constitution
Development of an interpretable machine learning model associated with genetic indicators to identify Yin-deficiency constitution
Traditional Chinese Medicine (TCM) defines constitutions which are relevant to corresponding diseases among people. As one...
Gynostemma Pentaphyllum ameliorates CCl4-induced liver injury via PDK1/Bcl-2 pathway with comprehensive analysis of network pharmacology and transcriptomics
Gynostemma Pentaphyllum ameliorates CCl4-induced liver injury via PDK1/Bcl-2 pathway with comprehensive analysis of network pharmacology and transcriptomics
Gynostemma pentaphyllum (Thunb.) Makino, commonly known as “southern ginseng”, contains high amounts of ginsen...
Cirsilineol inhibits RANKL-induced osteoclast activity and ovariectomy-induced bone loss via NF-κb/ERK/p38 signaling pathways
Cirsilineol inhibits RANKL-induced osteoclast activity and ovariectomy-induced bone loss via NF-κb/ERK/p38 signaling pathways
Postmenopausal osteoporosis is a chronic metabolic bone disease caused by excessive osteoclast formation and function. Tar...
Acacetin alleviates autoimmune myocarditis by regulating CD4+ T cell mitochondrial respiration
Acacetin alleviates autoimmune myocarditis by regulating CD4+ T cell mitochondrial respiration
Myocarditis refers to an autoimmune inflammatory response of the myocardium with characterization of self-reactive CD4+...
Systematic investigation of the material basis, effectiveness and safety of Thesium chinense Turcz. and its preparation Bairui Granules against lung inflammation
Systematic investigation of the material basis, effectiveness and safety of Thesium chinense Turcz. and its preparation Bairui Granules against lung inflammation
Thesium chinense Turcz. (Named as Bai Rui Cao in Chinese) and its preparations (e.g., Bairui Granules) have been used to t...
Traditional uses, phytochemistry, pharmacology, quality control and clinical studies of Cimicifugae Rhizoma: a comprehensive review
Traditional uses, phytochemistry, pharmacology, quality control and clinical studies of Cimicifugae Rhizoma: a comprehensive review
Cimicifugae Rhizoma, generally known as “Sheng Ma” in China, has great medicinal and dietary values. Cimicifug...
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