SCI时时刷

search
+
Metabolomics and proteomics analyses of Chrysanthemi Flos: a mechanism study of changes in proteins and metabolites by processing methods
Metabolomics and proteomics analyses of Chrysanthemi Flos: a mechanism study of changes in proteins and metabolites by processing methods
Chrysanthemi Flos is a traditional Chinese medicine with a long history of medicinal use. Prior research suggests that the...
Potential of natural products and gut microbiome in tumor immunotherapy
Potential of natural products and gut microbiome in tumor immunotherapy
Immunotherapy is a novel treatment approach for malignant tumors, which has opened a new journey of anti-tumor therapy. Al...
Taraxerone inhibits M1 polarization and alleviates sepsis-induced acute lung injury by activating SIRT1
Taraxerone inhibits M1 polarization and alleviates sepsis-induced acute lung injury by activating SIRT1
Acute lung injury (ALI) is the most lethal disease associated with sepsis, and there is a lack of effective drug treatment...
Periplaneta americana L. extract exerts neuroprotective effects by inhibiting endoplasmic reticulum stress via AKT-dependent pathway in experimental models of Parkinson’s disease
Periplaneta americana L. extract exerts neuroprotective effects by inhibiting endoplasmic reticulum stress via AKT-dependent pathway in experimental models of Parkinson’s disease
Parkinson’s disease (PD) is a chronic neurodegenerative disorder that currently has no curable strategies. More and ...
An integrated approach for studying exposure, metabolism, and disposition of traditional Chinese medicine using PATBS and MDRB tools: a case study of semen Armeniacae Amarum
An integrated approach for studying exposure, metabolism, and disposition of traditional Chinese medicine using PATBS and MDRB tools: a case study of semen Armeniacae Amarum
Deciphering the in vivo processes of traditional Chinese medicine (TCM) is crucial for identifying new pharmacodynamic sub...
Electroacupuncture alleviates neuropathic pain in a rat model of CCD via suppressing P2X3 expression in dorsal root ganglia
Electroacupuncture alleviates neuropathic pain in a rat model of CCD via suppressing P2X3 expression in dorsal root ganglia
Sciatica and low back pain are prevalent clinical types of neuropathic pain that significantly impair patients' qualit...
Clinical efficacy of DSA-based features in predicting outcomes of acupuncture intervention on upper limb dysfunction following ischemic stroke
Clinical efficacy of DSA-based features in predicting outcomes of acupuncture intervention on upper limb dysfunction following ischemic stroke
This study aimed to employ machine learning techniques to predict the clinical efficacy of acupuncture as an intervention ...
Efficacy and safety of Shengjiang Xiexin decoction on irinotecan-induced diarrhea in small cell lung cancer patients: a multicenter, randomized, double-blind, placebo-controlled trial
Efficacy and safety of Shengjiang Xiexin decoction on irinotecan-induced diarrhea in small cell lung cancer patients: a multicenter, randomized, double-blind, placebo-controlled trial
Irinotecan is a standard chemotherapeutic agent in small cell lung cancer (SCLC), however, as a common adverse reaction, d...
Ren-Shen-Bu-Qi decoction alleviates exercise fatigue through activating PI3K/AKT/Nrf2 pathway in mice
Ren-Shen-Bu-Qi decoction alleviates exercise fatigue through activating PI3K/AKT/Nrf2 pathway in mice
Fatigue is a prevalent issue that can lead individuals to a sub-health condition, impacting their work efficiency and qual...
Suppression of ferroptosis through the SLC7A11/glutathione/glutathione peroxidase 4 axis contributes to the therapeutic action of the Tangshenning formula on diabetic renal tubular injury
Suppression of ferroptosis through the SLC7A11/glutathione/glutathione peroxidase 4 axis contributes to the therapeutic action of the Tangshenning formula on diabetic renal tubular injury
Tangshenning (TSN) is a safe and effective formula to treat diabetic nephropathy (DN), and clinical studies have demonstra...
The role of Chinese herbal medicine in the regulation of oxidative stress in treating hypertension: from therapeutics to mechanisms
The role of Chinese herbal medicine in the regulation of oxidative stress in treating hypertension: from therapeutics to mechanisms
Although the pathogenesis of essential hypertension is not clear, a large number of studies have shown that oxidative stre...
Protective effect of Huashi Baidu formula against AKI and active ingredients that target SphK1 and PAI-1
Protective effect of Huashi Baidu formula against AKI and active ingredients that target SphK1 and PAI-1
Huashi Baidu Formula (HBF) is a clinical formula known for its efficacy against coronavirus disease 2019 (COVID-19). HBF m...
Shen-Bai-Jie-Du decoction suppresses the progression of colorectal adenoma to carcinoma through regulating gut microbiota and short-chain fatty acids
Shen-Bai-Jie-Du decoction suppresses the progression of colorectal adenoma to carcinoma through regulating gut microbiota and short-chain fatty acids
Shen-Bai-Jie-Du decoction (SBJDD), a traditional Chinese herb formula developed based on evidence-based medicine, is effic...
Metabolic reprogramming and renal fibrosis: what role might Chinese medicine play?
Metabolic reprogramming and renal fibrosis: what role might Chinese medicine play?
Metabolic reprogramming is a pivotal biological process in which cellular metabolic patterns change to meet the energy dem...
Zhi-Kang-Yin formula attenuates high-fat diet-induced metabolic disorders through modulating gut microbiota-bile acids axis in mice
Zhi-Kang-Yin formula attenuates high-fat diet-induced metabolic disorders through modulating gut microbiota-bile acids axis in mice
Metabolic disorders have become one of the global medical problems. Due to the complexity of its pathogenesis, there is st...
Correction: Total tanshinones ameliorates cGAS-STING-mediated inflammatory and autoimmune diseases by affecting STING-IRF3 binding
Correction: Total tanshinones ameliorates cGAS-STING-mediated inflammatory and autoimmune diseases by affecting STING-IRF3 binding
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Correction: The improvement of modified Si-Miao granule on hepatic insulin resistance and glycogen synthesis in type 2 diabetes mellitus involves the inhibition of TNF-α/JNK1/IRS-2 pathway: network pharmacology, molecular docking, and experimental validation
Correction: The improvement of modified Si-Miao granule on hepatic insulin resistance and glycogen synthesis in type 2 diabetes mellitus involves the inhibition of TNF-α/JNK1/IRS-2 pathway: network pharmacology, molecular docking, and experimental validation
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
PrescDRL: deep reinforcement learning for herbal prescription planning in treatment of chronic diseases
PrescDRL: deep reinforcement learning for herbal prescription planning in treatment of chronic diseases
Treatment planning for chronic diseases is a critical task in medical artificial intelligence, particularly in traditional...
Yiqihuoxue decoction (GSC) inhibits mitochondrial fission through the AMPK pathway to ameliorate EPCs senescence and optimize vascular aging transplantation regimens
Yiqihuoxue decoction (GSC) inhibits mitochondrial fission through the AMPK pathway to ameliorate EPCs senescence and optimize vascular aging transplantation regimens
During the aging process, the number and functional activity of endothelial progenitor cells (EPCs) are impaired, leading ...
Integrated serum pharmacochemistry, 16S rDNA sequencing, and metabolomics to reveal the material basis and mechanism of Shouhui Tongbian capsule against diphenoxylate-induced slow transit constipation in rats
Integrated serum pharmacochemistry, 16S rDNA sequencing, and metabolomics to reveal the material basis and mechanism of Shouhui Tongbian capsule against diphenoxylate-induced slow transit constipation in rats
Slow transit constipation (STC) is highly prevalent and has rising incidence. Shouhui Tongbian capsule (SHTB) is a traditi...
Applications of nanomaterials with enzyme-like activity for the detection of phytochemicals and hazardous substances in plant samples
Applications of nanomaterials with enzyme-like activity for the detection of phytochemicals and hazardous substances in plant samples
Plants such as herbs, vegetables, fruits, and cereals are closely related to human life. Developing effective testing meth...
Identification of molecular targets of Hypericum perforatum in blood for major depressive disorder: a machine-learning pharmacological study
Identification of molecular targets of Hypericum perforatum in blood for major depressive disorder: a machine-learning pharmacological study
Major depressive disorder (MDD) is one of the most common psychiatric disorders worldwide. Hypericum perforatum (HP) is a ...
Puerarin: a hepatoprotective drug from bench to bedside
Puerarin: a hepatoprotective drug from bench to bedside
Pueraria is a time-honored food and medicinal plant, which is widely used in China. Puerarin, the main component extracted...
Molecular quantification of fritillariae cirrhosae bulbus and its adulterants
Molecular quantification of fritillariae cirrhosae bulbus and its adulterants
Fritillariae Cirrhosae Bulbus (FCB) is frequently adulterated with its closely related species due to personal or non-man ...
Proteomic analysis and experimental validation reveal the blood–brain barrier protective of Huanshaodan in the treatment of SAMP8 mouse model of Alzheimer’s disease
Proteomic analysis and experimental validation reveal the blood–brain barrier protective of Huanshaodan in the treatment of SAMP8 mouse model of Alzheimer’s disease
Huanshaodan (HSD) is a Chinese Herbal Compound which has a definite clinical effect on Alzheimer’s disease (AD), how...
Acupuncture may play a key role in anti-depression through various mechanisms in depression
Acupuncture may play a key role in anti-depression through various mechanisms in depression
Depression has emerged as a significant global health concern, exerting a profound impact on individuals, as evidenced by ...
Uncovering the role of traditional Chinese medicine in immune-metabolic balance of gastritis from the perspective of Cold and Hot: Jin Hong Tablets as a case study
Uncovering the role of traditional Chinese medicine in immune-metabolic balance of gastritis from the perspective of Cold and Hot: Jin Hong Tablets as a case study
Chronic gastritis (CG) is a common inflammatory disease of chronic inflammatory lesion of gastric mucosa and in the diagno...
Development of a new paradigm model for deciphering action mechanism of Danhong injection using a combination of isothermal shift assay and database interrogation
Development of a new paradigm model for deciphering action mechanism of Danhong injection using a combination of isothermal shift assay and database interrogation
Identification of active components of traditional Chinese Medicine (TCM) and their respective targets is important for un...
Unveiling correlations between aristolochic acids and liver cancer: spatiotemporal heterogeneity phenomenon
Unveiling correlations between aristolochic acids and liver cancer: spatiotemporal heterogeneity phenomenon
Aristolochic acids are a class of naturally occurring compounds in Aristolochiaceae that have similar structural skeletons...
Correction: Electroacupuncture negatively regulates the Nesfatin-1/ERK/CREB pathway to alleviate HPA axis hyperactivity and anxiety-like behaviors caused by surgical trauma
Correction: Electroacupuncture negatively regulates the Nesfatin-1/ERK/CREB pathway to alleviate HPA axis hyperactivity and anxiety-like behaviors caused by surgical trauma
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
阅读更多
format_indent_increase