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Circulating endothelial cell (CEC) kinetic in patients with Multiple Myeloma (MM) who receive Au-HSCT (Autologous Hematopoietic Stem Cell Transplantation)
Circulating endothelial cell (CEC) kinetic in patients with Multiple Myeloma (MM) who receive Au-HSCT (Autologous Hematopoietic Stem Cell Transplantation)
Introduction: Neoangiogenesis has a crucial role in Multiple Myeloma (MM) and Circulating Endothelial Cells (CECs) contrib...
Arrhythmia in Bruton Tyrosine Kinase Inhibitor treated patients: Unanswered Questions
Arrhythmia in Bruton Tyrosine Kinase Inhibitor treated patients: Unanswered Questions
(No abstract allowed for commentary)
Long Non-Coding RNA BCAR4 Promotes Oxaliplatin Resistance in Colorectal Cancer by Modulating miR-484-3p/RAB5C Expression
Long Non-Coding RNA BCAR4 Promotes Oxaliplatin Resistance in Colorectal Cancer by Modulating miR-484-3p/RAB5C Expression
<b><i>Background:</i></b> Oxaliplatin-based chemotherapy resistance is a major cause of recurrence...
Impact of Pretransplant Salvage Therapies on Outcome of Hodgkin Lymphoma Patients Performing Allogeneic Transplant
Impact of Pretransplant Salvage Therapies on Outcome of Hodgkin Lymphoma Patients Performing Allogeneic Transplant
<b><i>Background:</i></b> Allogeneic transplant is an effective salvage therapy in patients with H...
LncRNA BCAR4 promotes oxaliplatin resistance in colorectal cancer by modulating miR-484-3p/RAB5C expression
LncRNA BCAR4 promotes oxaliplatin resistance in colorectal cancer by modulating miR-484-3p/RAB5C expression
Background Oxaliplatin based chemotherapy resistance is a major cause of recurrence in patients with colorectal cancer (CR...
Evaluation of a novel combination therapy, based on trifluridine/tipiracil and fruquintinib, against colorectal cancer
Evaluation of a novel combination therapy, based on trifluridine/tipiracil and fruquintinib, against colorectal cancer
Introduction: Trifluridine/tipiracil hydrochloride (FTD/TPI, Lonsurf®) is an oral antineoplastic agent that has been ...
Initial therapeutic approach with pembrolizumab in synchronous multiple cancers, including non-small cell lung cancer highly positive for programmed death-ligand 1 expression
Initial therapeutic approach with pembrolizumab in synchronous multiple cancers, including non-small cell lung cancer highly positive for programmed death-ligand 1 expression
Treatment of synchronous multiple primary cancers is clinically difficult. We report four cases of synchronous primary ca...
IMPACT OF PRE TRANSPLANT SALVAGE THERAPIES ON OUTCOME OF HODGKIN LYMPHOMA PATIENTS PERFORMING ALLOGENEIC TRANSPLANT
IMPACT OF PRE TRANSPLANT SALVAGE THERAPIES ON OUTCOME OF HODGKIN LYMPHOMA PATIENTS PERFORMING ALLOGENEIC TRANSPLANT
Background: Allogeneic transplant is an effective salvage therapy in patients with Hodgkin lymphoma (HL) relapsed or refra...
Drug Interactions Causing Warfarin Overdose in a Patient with Pancreatic Cancer: A Case Report
Drug Interactions Causing Warfarin Overdose in a Patient with Pancreatic Cancer: A Case Report
Mistletoe, <i>Viscum album</i>, is a medicinal plant used in complementary medicine in oncology. Patients do n...
Drug interactions causing warfarin overdose in a patient with a pancreatic cancer : a case report.
Drug interactions causing warfarin overdose in a patient with a pancreatic cancer : a case report.
Mistletoe, Viscum album, is a medicinal plant used in complementary medicine in oncology. Patients don’t necessarily menti...
Contents Vol. 67, 2022
Contents Vol. 67, 2022
Chemotherapy...
Ibrutinib and Bruton’s tyrosine kinase inhibitors in chronic lymphocytic leukemia: focus on atrial fibrillation and ventricular tachyarrhythmias/sudden cardiac death
Ibrutinib and Bruton’s tyrosine kinase inhibitors in chronic lymphocytic leukemia: focus on atrial fibrillation and ventricular tachyarrhythmias/sudden cardiac death
Background: The natural history of chronic lymphocytic leukemia (CLL) was dramatically improved by the introduction of ibr...
Targeted therapy of non-small cell lung cancer and liver cancer: functional nanocarriers for the delivery of cisplatin and tissue factor pathway inhibitor-2
Targeted therapy of non-small cell lung cancer and liver cancer: functional nanocarriers for the delivery of cisplatin and tissue factor pathway inhibitor-2
Introduction: To construct folic acid-modified PEGylated paramagnetic nanoparticles (MNP) co-carrying tissue factor pathwa...
Fulminant type 1 diabetes mellitus caused by long-term nivolumab administration followed by nivolumab plus cabozantinib combination
Fulminant type 1 diabetes mellitus caused by long-term nivolumab administration followed by nivolumab plus cabozantinib combination
Nivolumab, an immune checkpoint inhibitor (ICI), is now used to treat many advanced cancers, including non-small cell lung...
Clinical analysis of extrapulmonary neuroendocrine carcinoma: a retrospective and single institution experience
Clinical analysis of extrapulmonary neuroendocrine carcinoma: a retrospective and single institution experience
Introduction: Extrapulmonary neuroendocrine carcinoma (EPNEC) is a clinicopathological entity distinct from neuroendocrine...
MIC Discrepancies between Parenteral and Oral Anti-Staphylococcal Beta-Lactams among MSSA
MIC Discrepancies between Parenteral and Oral Anti-Staphylococcal Beta-Lactams among MSSA
<b><i>Introduction:</i></b> Recent evidence has shown that oral antibiotic therapy is not inferior...
Initiating treatment with low Fluorouracil dose and titrating according to blood levels in patients treated with a 46-hour continuous infusion.
Initiating treatment with low Fluorouracil dose and titrating according to blood levels in patients treated with a 46-hour continuous infusion.
Introduction: Fluorouracil (5-FU) pharmacokinetics are variable, leading to risk of toxicity in some patients and under-do...
Does the Timing of Eribulin Treatment for Advanced or Metastatic Breast Cancer Matter? Evidence from a Real-World Setting
Does the Timing of Eribulin Treatment for Advanced or Metastatic Breast Cancer Matter? Evidence from a Real-World Setting
Background: This study aimed to examine the effectiveness and safety of eribulin used as an early-line (i.e., first/second...
SARS-CoV-2 infection in patients treated with azacitidine and venetoclax for acute leukemia – a report of a case series treated in a single institution
SARS-CoV-2 infection in patients treated with azacitidine and venetoclax for acute leukemia – a report of a case series treated in a single institution
Introduction Venetoclax combined with azacitidine (AZA-VEN) constitutes an option for the treatment of acute myeloid leuke...
MIC discrepancies between parenteral and oral anti-staphylococcal β-lactams among MSSA
MIC discrepancies between parenteral and oral anti-staphylococcal β-lactams among MSSA
Introduction: Recent evidence has shown that oral antibiotic therapy is not inferior to IV antibiotic therapy in the treat...
Safety Signal between Azacitidine and Pericarditis
Safety Signal between Azacitidine and Pericarditis
Background: Drug-induced pericarditis is an important cause of pericarditis and if un-noticed and un-managed can lead to c...
Curcumin Suppresses the Progression of Colorectal Cancer by Improving Immunogenic Cell Death Caused by Irinotecan
Curcumin Suppresses the Progression of Colorectal Cancer by Improving Immunogenic Cell Death Caused by Irinotecan
<b><i>Background:</i></b> Irinotecan (IRI) is a common chemotherapeutic drug for colorectal cancer...
Lung Adenocarcinoma Harboring Triple Rare EGFR Exon 18 Mutations Rapidly Developed Resistance to Multiple Therapies
Lung Adenocarcinoma Harboring Triple Rare EGFR Exon 18 Mutations Rapidly Developed Resistance to Multiple Therapies
There is no standard therapy for nonsmall-cell lung cancer harboring rare coexistent EGFR mutations. Here, we report a fem...
Treatment Tolerance of Cetuximab versus Alternative Chemotherapy Agents in Non-Cisplatin Candidates with Head and Neck Cancer Receiving Concurrent Chemoradiotherapy
Treatment Tolerance of Cetuximab versus Alternative Chemotherapy Agents in Non-Cisplatin Candidates with Head and Neck Cancer Receiving Concurrent Chemoradiotherapy
Abstract Introduction: Standard of care for radiosensitization in head and neck squamous cell carcinoma (HNSCC) is concur...
Fusidic acid and its major active metabolite penetration into cerebrospinal fluid for assessing treatment of intracranial infections.
Fusidic acid and its major active metabolite penetration into cerebrospinal fluid for assessing treatment of intracranial infections.
Fusidic acid (FA) had the excellent antimicrobial effects due to its unique mechanism of action. Since 1962, FA has been w...
Lung adenocarcinoma harboring triple rare EGFR exon18 mutations rapidly developed resistance to multiple therapies
Lung adenocarcinoma harboring triple rare EGFR exon18 mutations rapidly developed resistance to multiple therapies
Non-small cell lung cancer (NSCLC) is the leading cause of cancer related deaths worldwide. Its medical significance has s...
How I treat localized soft tissue sarcomas: update on diagnosis, risk-stratification and treatment
How I treat localized soft tissue sarcomas: update on diagnosis, risk-stratification and treatment
Background: Adult-type soft tissue sarcomas (STS) are rare tumors representing about 1% of all adult malignant tumors. The...
Paraneoplastic Demyelinating Inflammatory Neuropathy Revealing Metastatic Seminoma: A Case Report
Paraneoplastic Demyelinating Inflammatory Neuropathy Revealing Metastatic Seminoma: A Case Report
Paraneoplastic neurological syndrome (PNS) is uncommon and not well known. PNS can reveal cancer, but its role in seminoma...
Examining the Combination of Cefixime and Amoxicillin/Clavulanate against Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Isolates
Examining the Combination of Cefixime and Amoxicillin/Clavulanate against Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Isolates
<b><i>Introduction:</i></b> Community-acquired urinary tract infections (UTIs) caused by extended-...
Circular RNA hsa_circ_0068252 functions in cisplatin resistance and immune response via miR-1304-5p/PD-L1 axis in non-small cell lung cancer
Circular RNA hsa_circ_0068252 functions in cisplatin resistance and immune response via miR-1304-5p/PD-L1 axis in non-small cell lung cancer
Background: Research suggests that circRNAs play important roles in non-small cell lung cancer (NSCLC). The function of hs...
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