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Does the Timing of Eribulin Treatment for Advanced or Metastatic Breast Cancer Matter? Evidence from a Real-World Setting
Does the Timing of Eribulin Treatment for Advanced or Metastatic Breast Cancer Matter? Evidence from a Real-World Setting
Background: This study aimed to examine the effectiveness and safety of eribulin used as an early-line (i.e., first/second...
MIC discrepancies between parenteral and oral anti-staphylococcal β-lactams among MSSA
MIC discrepancies between parenteral and oral anti-staphylococcal β-lactams among MSSA
Introduction: Recent evidence has shown that oral antibiotic therapy is not inferior to IV antibiotic therapy in the treat...
Safety Signal between Azacitidine and Pericarditis
Safety Signal between Azacitidine and Pericarditis
Background: Drug-induced pericarditis is an important cause of pericarditis and if un-noticed and un-managed can lead to c...
Lung Adenocarcinoma Harboring Triple Rare EGFR Exon 18 Mutations Rapidly Developed Resistance to Multiple Therapies
Lung Adenocarcinoma Harboring Triple Rare EGFR Exon 18 Mutations Rapidly Developed Resistance to Multiple Therapies
There is no standard therapy for nonsmall-cell lung cancer harboring rare coexistent EGFR mutations. Here, we report a fem...
Fusidic acid and its major active metabolite penetration into cerebrospinal fluid for assessing treatment of intracranial infections.
Fusidic acid and its major active metabolite penetration into cerebrospinal fluid for assessing treatment of intracranial infections.
Fusidic acid (FA) had the excellent antimicrobial effects due to its unique mechanism of action. Since 1962, FA has been w...
Lung adenocarcinoma harboring triple rare EGFR exon18 mutations rapidly developed resistance to multiple therapies
Lung adenocarcinoma harboring triple rare EGFR exon18 mutations rapidly developed resistance to multiple therapies
Non-small cell lung cancer (NSCLC) is the leading cause of cancer related deaths worldwide. Its medical significance has s...
How I treat localized soft tissue sarcomas: update on diagnosis, risk-stratification and treatment
How I treat localized soft tissue sarcomas: update on diagnosis, risk-stratification and treatment
Background: Adult-type soft tissue sarcomas (STS) are rare tumors representing about 1% of all adult malignant tumors. The...
Paraneoplastic Demyelinating Inflammatory Neuropathy Revealing Metastatic Seminoma: A Case Report
Paraneoplastic Demyelinating Inflammatory Neuropathy Revealing Metastatic Seminoma: A Case Report
Paraneoplastic neurological syndrome (PNS) is uncommon and not well known. PNS can reveal cancer, but its role in seminoma...
Circular RNA hsa_circ_0068252 functions in cisplatin resistance and immune response via miR-1304-5p/PD-L1 axis in non-small cell lung cancer
Circular RNA hsa_circ_0068252 functions in cisplatin resistance and immune response via miR-1304-5p/PD-L1 axis in non-small cell lung cancer
Background: Research suggests that circRNAs play important roles in non-small cell lung cancer (NSCLC). The function of hs...
Hepatosplenic T-cell non-Hodgkin lymphoma cured with tandem autologous and allogeneic stem cell transplantation
Hepatosplenic T-cell non-Hodgkin lymphoma cured with tandem autologous and allogeneic stem cell transplantation
Hepatosplenic T-cell lymphoma is a very difficult lymphoma to deal with, almost impossible to cure. “Tandem” consolidation...
Clinical Outcomes of Postoperative Adjuvant Chemotherapy for Surgically Resected High-Grade Pulmonary Neuroendocrine Carcinoma
Clinical Outcomes of Postoperative Adjuvant Chemotherapy for Surgically Resected High-Grade Pulmonary Neuroendocrine Carcinoma
Introduction: Data on the clinical outcomes of patients receiving adjuvant chemotherapy for surgically resected high-grade...
Quercetin Inhibits Glioblastoma Growth and Prolongs Survival Rate through Inhibiting Glycolytic Metabolism
Quercetin Inhibits Glioblastoma Growth and Prolongs Survival Rate through Inhibiting Glycolytic Metabolism
Introduction: Quercetin has been reported to have anti-tumor activity of a wide range of cancers, including breast, lung, ...
Rituximab and Chemotherapy for Newly Diagnosed Follicular Lymphoma - Real World Report of Polish Lymphoma Research Group
Rituximab and Chemotherapy for Newly Diagnosed Follicular Lymphoma - Real World Report of Polish Lymphoma Research Group
Introduction: Follicular lymphoma (FL) is the most common type of indolent B cell lymphoma with a favorable prognosis in t...
Body Mass Index of Elderly Patients with Normal Renal Function as a Determining Factor for Initial Vancomycin Regimen Designing
Body Mass Index of Elderly Patients with Normal Renal Function as a Determining Factor for Initial Vancomycin Regimen Designing
Introduction: Currently, the use of actual body weight is recommended for dosing in vancomycin regimen designs and it is i...
Efficacy and Safety of Super-Selective Bronchial Arterial Infusion Chemotherapy in the Treatment of Advanced Non-Small Cell Lung Cancer
Efficacy and Safety of Super-Selective Bronchial Arterial Infusion Chemotherapy in the Treatment of Advanced Non-Small Cell Lung Cancer
Objective: To study the effectiveness and safety of super-selective bronchial arterial infusion (SBAI) chemotherapy in the...
The Effect of High CDC6 Levels on Predicting Poor Prognosis in Colorectal Cancer
The Effect of High CDC6 Levels on Predicting Poor Prognosis in Colorectal Cancer
<b><i>Introduction:</i></b> We investigated the function of cell division cycle 6 (CDC6) on the pr...
New Frontiers in the Medical Therapy of Hepatocellular Carcinoma
New Frontiers in the Medical Therapy of Hepatocellular Carcinoma
Background: Hepatocellular carcinoma (HCC) is the most common primary liver tumor, and it rates fourth as a cause of cance...
KIT Exon 9-Mutated Gastrointestinal Stromal Tumours: Biology and Treatment
KIT Exon 9-Mutated Gastrointestinal Stromal Tumours: Biology and Treatment
Background. The majority of gastroinstestinal stromal tumours (GISTs) harbour oncogenic mutations in the gene encoding for...
Sarcopenia in Hepatocellular Carcinoma: Pathogenesis and Management
Sarcopenia in Hepatocellular Carcinoma: Pathogenesis and Management
Background: Sarcopenia is almost constantly observed in patients with cirrhosis and hepatocellular carcinoma. Summary: C...