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Epilepsy as a Wilding of Sleep
Epilepsy as a Wilding of Sleep
To review the mutual links of sleep and epilepsy. It is supported in several ways that epilepsy is ‘born’ in s...
The Impacts of the Covid-19 Pandemic on Cerebral Infarction Treatment: Challenges and Opportunities
The Impacts of the Covid-19 Pandemic on Cerebral Infarction Treatment: Challenges and Opportunities
This paper summarizes recent literature on the pandemic's effects on IS treatment. The literature is searched in popul...
Epstein-Barr Virus as a Therapeutic and Preventive Target in Multiple Sclerosis
Epstein-Barr Virus as a Therapeutic and Preventive Target in Multiple Sclerosis
Epstein-Barr virus (EBV) is the likely cause of multiple sclerosis (MS). However, its role in the pathogenesis of MS remai...
Inhibiting CD40 Ligand in Multiple Sclerosis: A Review of Emerging Therapeutic Potential
Inhibiting CD40 Ligand in Multiple Sclerosis: A Review of Emerging Therapeutic Potential
Current high-efficacy disease-modifying therapies for multiple sclerosis (MS) primarily target adaptive immune cells in pe...
A Hypoxia-Inflammation Cycle and Multiple Sclerosis: Mechanisms and Therapeutic Implications
A Hypoxia-Inflammation Cycle and Multiple Sclerosis: Mechanisms and Therapeutic Implications
Multiple sclerosis (MS) is a complex neurodegenerative disease characterized by inflammation, demyelination, and neurodege...
Education and Team Science in Neurocritical Care
Education and Team Science in Neurocritical Care
Education in neurocritical care (NCC) is evolving, and there is a rapidly growing interest in applying the principles of t...
Treatment of Downbeat Nystagmus and Cerebellar Ataxia
Treatment of Downbeat Nystagmus and Cerebellar Ataxia
Downbeat nystagmus (DBN) and cerebellar ataxia present significant challenges in shared clinical management. This review a...
Strategic De-escalation of Disease-Modifying Therapies in Elderly Patients: Approaches and Considerations
Strategic De-escalation of Disease-Modifying Therapies in Elderly Patients: Approaches and Considerations
This review presents a summary of the literature on de-escalation and discontinuation of disease-modifying therapies (DMTs...
Postoperative Neurosurgical Complications in Neurocritical Care
Postoperative Neurosurgical Complications in Neurocritical Care
The purpose of this review is to identify risks of neurosurgical procedures with emphasis on general medical and surgical ...
Neurocritical Care in Transplant Patients
Neurocritical Care in Transplant Patients
This review aims to summarize important aspects of clinical presentations, updates on diagnostic methods, and current trea...
Treatment of Obstructive Sleep Apnea in patients with Alzheimer’s Disease: role of Continuous Positive Airway Pressure therapy
Treatment of Obstructive Sleep Apnea in patients with Alzheimer’s Disease: role of Continuous Positive Airway Pressure therapy
Obstructive Sleep Apnea (OSA) is a frequent comorbidity in patients with Alzheimer’s Disease (AD). This narrative re...
Update on Simulation in Neurocritical Care – Current Applications and Future Directions
Update on Simulation in Neurocritical Care – Current Applications and Future Directions
This review presents a critical appraisal of the current state of simulation-based education in neurocritical care, includ...
Current and Emerging Sleep Interventions for Older Adults with or without Mild Cognitive Impairment
Current and Emerging Sleep Interventions for Older Adults with or without Mild Cognitive Impairment
This systematic scoping review examines evidence from the last five years on sleep interventions in cognitive healthy olde...
The Impact of Epstein-Barr Virus on Autoimmune Neuromuscular Disorders: A Comparative Study of Myasthenia Gravis and Guillain–Barre Syndrome
The Impact of Epstein-Barr Virus on Autoimmune Neuromuscular Disorders: A Comparative Study of Myasthenia Gravis and Guillain–Barre Syndrome
The aim is to elucidate the mechanisms of autoimmune dysregulation that contribute to the onset and course of Gui...
Multicolumn Spinal Cord Stimulation for Chronic Back and Leg Pain in Patients with Failed Back Surgery Syndrome: A Systematic Review and Meta-Analysis
Multicolumn Spinal Cord Stimulation for Chronic Back and Leg Pain in Patients with Failed Back Surgery Syndrome: A Systematic Review and Meta-Analysis
Failed Back Surgery Syndrome (FBSS) presents a formidable challenge, marked by the persistence of chronic lower back pain ...
Genetic Testing for Epilepsy: A User Guide
Genetic Testing for Epilepsy: A User Guide
About 30% of epilepsy cases have an underlying genetic etiology. Despite rapid progress with understanding the genetic und...
Mechanical Thrombectomy for Acute Ischemic Stroke: Current State and Future Directions
Mechanical Thrombectomy for Acute Ischemic Stroke: Current State and Future Directions
This review summarizes significant advancements in mechanical thrombectomy (MT) to treat acute ischemic stroke after the p...
Correction to: Diagnosis and Management of Progressive Corticobasal Syndrome
Correction to: Diagnosis and Management of Progressive Corticobasal Syndrome
Algorithm to guide clinical evaluation and management of corticobasal syndrome. Though a clinical exam only is not enough ...
Efficacy and Safety of Atogepant for Preventing Chronic and Episodic Migraines: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Efficacy and Safety of Atogepant for Preventing Chronic and Episodic Migraines: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Calcitonin gene-related peptide (CGRP) pathway modulators, such as atogepant, represent a novel therapeutic option for the...
Diagnosis and Management of Progressive Corticobasal Syndrome
Diagnosis and Management of Progressive Corticobasal Syndrome
The purpose of this review is to discuss the clinical, radiological, and neuropathological heterogeneity of corticobasal s...
Sleep Disorders in Adults with Intellectual Disability: Current Status and Future Directions
Sleep Disorders in Adults with Intellectual Disability: Current Status and Future Directions
We performed a narrative review of the current knowledge in epidemiology, mechanisms, clinical presentation, and treatment...
The Current Role of Valproic Acid in the Treatment of Epilepsy: A Glimpse into the Present of an Old Ally
The Current Role of Valproic Acid in the Treatment of Epilepsy: A Glimpse into the Present of an Old Ally
The primary purpose of this review is to explore the specific clinical scenarios where valproic acid demonstrates superior...
A Review of Calcitonin Gene-Related Peptide and Its Implications for Vestibular Disorders
A Review of Calcitonin Gene-Related Peptide and Its Implications for Vestibular Disorders
Calcitonin gene-related peptide (CGRP) is an inflammatory neuropeptide widely present throughout the body and involved in ...
Delving Into the Significance of Brain’s Collateral Circulation in the Era of Revascularization Therapy
Delving Into the Significance of Brain’s Collateral Circulation in the Era of Revascularization Therapy
This narrative review summarized the major studies focusing on the association between revascularization therapies (intrav...
Treatment of Malignant Cerebral Edema in Acute Ischemic Stroke
Treatment of Malignant Cerebral Edema in Acute Ischemic Stroke
To provide an updated summary on the diagnosis and treatment of patients with malignant cerebral edema after ischemic stro...
Update on Treatment of Idiopathic (and Non-Idiopathic) Orbital Inflammation
Update on Treatment of Idiopathic (and Non-Idiopathic) Orbital Inflammation
This review aims to provide a critical appraisal of current diagnostic and therapeutic strategies for patients with orbita...
Treatment Approaches in Pediatric Relapsing Autoimmune Encephalitis
Treatment Approaches in Pediatric Relapsing Autoimmune Encephalitis
Autoimmune encephalitis (AE) is increasingly recognized as a treatable cause of encephalitis in children. While prior obse...
Distinguishing Benign Rashes From Severe Skin Reactions From Anti-Seizure Medications
Distinguishing Benign Rashes From Severe Skin Reactions From Anti-Seizure Medications
This review describes risk factors for severe skin reactions to antiseizure medications (ASMs), the usage of updated tests...
Ethical Considerations in the Treatment of Cerebrovascular Disease
Ethical Considerations in the Treatment of Cerebrovascular Disease
To care for patients with cerebrovascular disease (CVD), neurointerventionalists, intensivists, and other healthcare provi...
Early Mobilization in Neurocritical Care
Early Mobilization in Neurocritical Care
Bed rest was a treatment recommended for critically ill patients admitted to the intensive care unit (ICU) that aimed to m...
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