SCI时时刷

search
+
Androgen receptor-mediated pharmacogenomic expression quantitative trait loci: implications for breast cancer response to AR-targeting therapy
Androgen receptor-mediated pharmacogenomic expression quantitative trait loci: implications for breast cancer response to AR-targeting therapy
Endocrine therapy is the most important treatment modality of breast cancer patients whose tumors express the estrogen rec...
Stromal lymphocytes are associated with upgrade of B3 breast lesions
Stromal lymphocytes are associated with upgrade of B3 breast lesions
Various histopathological, clinical and imaging parameters have been evaluated to identify a subset of women diagnosed wit...
Epigallocatechin gallate and curcumin inhibit Bcl-2: a pharmacophore and docking based approach against cancer
Epigallocatechin gallate and curcumin inhibit Bcl-2: a pharmacophore and docking based approach against cancer
The protein Bcl-2, well-known for its anti-apoptotic properties, has been implicated in cancer pathogenesis. Identifying t...
Associations between quantitative measures of mammographic density and terminal ductal lobular unit involution in Chinese breast cancer patients
Associations between quantitative measures of mammographic density and terminal ductal lobular unit involution in Chinese breast cancer patients
Higher mammographic density (MD), a radiological measure of the proportion of fibroglandular tissue in the breast, and low...
Functions of methyltransferase-like 3 in breast cancer: pathogenesis, drug resistance, and therapeutic target
Functions of methyltransferase-like 3 in breast cancer: pathogenesis, drug resistance, and therapeutic target
Breast cancer (BC) is a highly prevalent malignancy worldwide, with complex pathogenesis and treatment challenges. Researc...
GNA13 suppresses proliferation of ER+ breast cancer cells via ERα dependent upregulation of the MYC oncogene
GNA13 suppresses proliferation of ER+ breast cancer cells via ERα dependent upregulation of the MYC oncogene
GNA13 (Gα13) is one of two alpha subunit members of the G12/13 family of heterotrimeric G-proteins which mediate sign...
Promoter profiles in plasma CfDNA exhibits a potential utility of predicting the efficacy of neoadjuvant chemotherapy in breast cancer patients
Promoter profiles in plasma CfDNA exhibits a potential utility of predicting the efficacy of neoadjuvant chemotherapy in breast cancer patients
Gene expression profiles in breast tissue biopsies contain information related to chemotherapy efficacy. The promoter prof...
Evaluating the immunologically “cold” tumor microenvironment after treatment with immune checkpoint inhibitors utilizing PET imaging of CD4 + and CD8 + T cells in breast cancer mouse models
Evaluating the immunologically “cold” tumor microenvironment after treatment with immune checkpoint inhibitors utilizing PET imaging of CD4 + and CD8 + T cells in breast cancer mouse models
Immune-positron emission tomography (PET) imaging with tracers that target CD8 and granzyme B has shown promise in predict...
Circular RNA HSDL2 promotes breast cancer progression via miR-7978 ZNF704 axis and regulating hippo signaling pathway
Circular RNA HSDL2 promotes breast cancer progression via miR-7978 ZNF704 axis and regulating hippo signaling pathway
Circular RNAs (circRNAs) are a new group of endogenous RNAs recently found to be involved in the development of various di...
TFAP2A downregulation mediates tumor-suppressive effect of miR-8072 in triple-negative breast cancer via inhibiting SNAI1 transcription
TFAP2A downregulation mediates tumor-suppressive effect of miR-8072 in triple-negative breast cancer via inhibiting SNAI1 transcription
Triple-negative breast cancer (TNBC) represents a highly aggressive subset of breast malignancies characterized by its cha...
Association of early menarche with breast tumor molecular features and recurrence
Association of early menarche with breast tumor molecular features and recurrence
Early menarche is an established risk factor for breast cancer but its molecular contribution to tumor biology and prognos...
Trastuzumab-functionalized bionic pyrotinib liposomes for targeted therapy of HER2-positive breast cancer
Trastuzumab-functionalized bionic pyrotinib liposomes for targeted therapy of HER2-positive breast cancer
In this study, we prepared a bionic nanosystem of trastuzumab-functionalized SK-BR-3 cell membrane hybrid liposome-coated ...
Trends in chemotherapy use for early-stage breast cancer from 2006 to 2019
Trends in chemotherapy use for early-stage breast cancer from 2006 to 2019
Little is known about how use of chemotherapy has evolved in breast cancer patients. We therefore describe chemotherapy pa...
In situ HER2 RNA expression as a predictor of pathologic complete response of HER2-positive breast cancer patients receiving neoadjuvant chemotherapy and anti-HER2 targeted treatment
In situ HER2 RNA expression as a predictor of pathologic complete response of HER2-positive breast cancer patients receiving neoadjuvant chemotherapy and anti-HER2 targeted treatment
Immunohistochemistry (IHC) and in situ hybridization (ISH) remain standard biomarkers for therapeutic decisions in human e...
An essential gene signature of breast cancer metastasis reveals targetable pathways
An essential gene signature of breast cancer metastasis reveals targetable pathways
The differential gene expression profile of metastatic versus primary breast tumors represents an avenue for discovering n...
Pre-treatment peripheral blood immunophenotyping and response to neoadjuvant chemotherapy in operable breast cancer
Pre-treatment peripheral blood immunophenotyping and response to neoadjuvant chemotherapy in operable breast cancer
Tumor immune infiltration and peripheral blood immune signatures have prognostic and predictive value in breast cancer. Wh...
Hypoxia-mediated repression of pyruvate carboxylase drives immunosuppression
Hypoxia-mediated repression of pyruvate carboxylase drives immunosuppression
Metabolic plasticity mediates breast cancer survival, growth, and immune evasion during metastasis. However, how tumor cel...
Lasofoxifene as a potential treatment for aromatase inhibitor-resistant ER-positive breast cancer
Lasofoxifene as a potential treatment for aromatase inhibitor-resistant ER-positive breast cancer
Breast cancers treated with aromatase inhibitors (AIs) can develop AI resistance, which is often driven by estrogen recept...
Alpha-6 integrin deletion delays the formation of Brca1/p53-deficient basal-like breast tumors by restricting luminal progenitor cell expansion
Alpha-6 integrin deletion delays the formation of Brca1/p53-deficient basal-like breast tumors by restricting luminal progenitor cell expansion
The aberrant amplification of mammary luminal progenitors is at the origin of basal-like breast cancers associated with BR...
Inflammation at diagnosis and cognitive impairment two years later in breast cancer patients from the Canto-Cog study
Inflammation at diagnosis and cognitive impairment two years later in breast cancer patients from the Canto-Cog study
Inflammation could be related to cancer-related cognitive impairment (CRCI) and might be used as a predictive marker of lo...
Increased expression of REG3A promotes tumorigenic behavior in triple negative breast cancer cells
Increased expression of REG3A promotes tumorigenic behavior in triple negative breast cancer cells
Identifying new targets in triple negative breast cancer (TNBC) remains critical. REG3A (regenerating islet-derived protei...
NSUN2/YBX1 promotes the progression of breast cancer by enhancing HGH1 mRNA stability through m5C methylation
NSUN2/YBX1 promotes the progression of breast cancer by enhancing HGH1 mRNA stability through m5C methylation
RNA m5C methylation has been extensively implicated in the occurrence and development of tumors. As the main methyltransfe...
Unraveling malignant phenotype of peritumoral tissue: transcriptomic insights into early-stage breast cancer
Unraveling malignant phenotype of peritumoral tissue: transcriptomic insights into early-stage breast cancer
Early-stage invasive ductal carcinoma displays high survival rates due to early detection and treatments. However, there i...
Reproductive characteristics, menopausal status, race and ethnicity, and risk of breast cancer subtypes defined by ER, PR and HER2 status: the Breast Cancer Etiology in Minorities study
Reproductive characteristics, menopausal status, race and ethnicity, and risk of breast cancer subtypes defined by ER, PR and HER2 status: the Breast Cancer Etiology in Minorities study
Associations between reproductive factors and risk of breast cancer differ by subtype defined by joint estrogen receptor (...
Elevated expression of wildtype RhoC promotes ErbB2- and Pik3ca-induced mammary tumor formation
Elevated expression of wildtype RhoC promotes ErbB2- and Pik3ca-induced mammary tumor formation
Copy number gains in genes coding for Rho activating exchange factors as well as losses affecting genes coding for RhoGAP ...
Optimising the diagnostic accuracy of First post-contrAst SubtracTed breast MRI (FAST MRI) through interpretation-training: a multicentre e-learning study, mapping the learning curve of NHS Breast Screening Programme (NHSBSP) mammogram readers using an enriched dataset
Optimising the diagnostic accuracy of First post-contrAst SubtracTed breast MRI (FAST MRI) through interpretation-training: a multicentre e-learning study, mapping the learning curve of NHS Breast Screening Programme (NHSBSP) mammogram readers using an enriched dataset
Abbreviated breast MRI (FAST MRI) is being introduced into clinical practice to screen women with mammographically dense b...
EDI3 knockdown in ER-HER2+ breast cancer cells reduces tumor burden and improves survival in two mouse models of experimental metastasis
EDI3 knockdown in ER-HER2+ breast cancer cells reduces tumor burden and improves survival in two mouse models of experimental metastasis
Despite progress understanding the mechanisms underlying tumor spread, metastasis remains a clinical challenge. We identif...
Breast cancer patients enrolled in the Swiss mammography screening program “donna” demonstrate prolonged survival
Breast cancer patients enrolled in the Swiss mammography screening program “donna” demonstrate prolonged survival
We compared the survival rates of women with breast cancer (BC) detected within versus outside the mammography screening p...
Deep learning of mammogram images to reduce unnecessary breast biopsies: a preliminary study
Deep learning of mammogram images to reduce unnecessary breast biopsies: a preliminary study
Patients with a Breast Imaging Reporting and Data System (BI-RADS) 4 mammogram are currently recommended for biopsy. Howev...
Infrared laser moxibustion for cancer-related fatigue in breast cancer survivors: a randomized controlled trial
Infrared laser moxibustion for cancer-related fatigue in breast cancer survivors: a randomized controlled trial
Cancer-related fatigue (CRF) is a pervasive, persistent, and distressing symptom experienced by cancer patients, for which...
阅读更多
format_indent_increase