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Body mass index and breast cancer risk in premenopausal and postmenopausal East Asian women: a pooled analysis of 13 cohort studies
Body mass index and breast cancer risk in premenopausal and postmenopausal East Asian women: a pooled analysis of 13 cohort studies
It has been suggested that the association between body mass index and breast cancer risk differs between Asian women and ...
Clinical values of nuclear morphometric analysis in fibroepithelial lesions
Clinical values of nuclear morphometric analysis in fibroepithelial lesions
Fibroepithelial lesions (FELs) of the breast encompass a broad spectrum of lesions, ranging from commonly encountered fibr...
PTPN20 promotes metastasis through activating NF-κB signaling in triple-negative breast cancer
PTPN20 promotes metastasis through activating NF-κB signaling in triple-negative breast cancer
Cancer metastasis remains a major challenge in the clinical management of triple-negative breast cancer (TNBC). The NF- ...
The role of heparan sulfate in enhancing the chemotherapeutic response in triple-negative breast cancer
The role of heparan sulfate in enhancing the chemotherapeutic response in triple-negative breast cancer
Breast cancer, one of the most common forms of cancer, is associated with the highest cancer-related mortality among women...
Differentiating HER2-low and HER2-zero tumors with 21-gene multigene assay in 2,295 h + HER2- breast cancer: a retrospective analysis
Differentiating HER2-low and HER2-zero tumors with 21-gene multigene assay in 2,295 h + HER2- breast cancer: a retrospective analysis
HER2-positivity is an essential marker for therapeutic decisions, while HER2 expression is heterogenous. In recent years, ...
Breast cancer in women with previous gestational diabetes: a nationwide register-based cohort study
Breast cancer in women with previous gestational diabetes: a nationwide register-based cohort study
Gestational diabetes mellitus (GDM) is a common pregnancy complication characterized by insulin resistance. A link has bee...
Predicting pathologic complete response to neoadjuvant chemotherapy in breast cancer using a machine learning approach
Predicting pathologic complete response to neoadjuvant chemotherapy in breast cancer using a machine learning approach
For patients with breast cancer undergoing neoadjuvant chemotherapy (NACT), most of the existing prediction models of path...
Transcriptomic analysis identifies enrichment of cAMP/PKA/CREB signaling in invasive lobular breast cancer
Transcriptomic analysis identifies enrichment of cAMP/PKA/CREB signaling in invasive lobular breast cancer
Invasive lobular breast cancer (ILC) is the most common special type of breast cancer and has unique clinicopathological a...
Effect of genistein supplementation on microenvironment regulation of breast tumors in obese mice
Effect of genistein supplementation on microenvironment regulation of breast tumors in obese mice
Obesity is an important risk factor for breast cancer in women before and after menopause. Adipocytes, key mediators in th...
Ribosomal S6 kinase (RSK) plays a critical role in DNA damage response via the phosphorylation of histone lysine demethylase KDM4B
Ribosomal S6 kinase (RSK) plays a critical role in DNA damage response via the phosphorylation of histone lysine demethylase KDM4B
Epigenetic dysregulation affecting oncogenic transcription and DNA damage response is a hallmark of cancer. The histone de...
Increasing rates of early-onset Luminal A breast cancers correlate with binge drinking patterns
Increasing rates of early-onset Luminal A breast cancers correlate with binge drinking patterns
Breast cancer (BC) rates have been increasing in young women in the U.S. Alcohol is an established risk factor for breast ...
Pro-inflammatory cytokines increase temporarily after adjuvant treatment for breast cancer in postmenopausal women: a longitudinal study
Pro-inflammatory cytokines increase temporarily after adjuvant treatment for breast cancer in postmenopausal women: a longitudinal study
Breast cancer patients have an increased risk of cardiometabolic disease and for many patients, adjuvant therapy causes an...
Autophagy is required for mammary tumor recurrence by promoting dormant tumor cell survival following therapy
Autophagy is required for mammary tumor recurrence by promoting dormant tumor cell survival following therapy
Mortality from breast cancer is principally due to tumor recurrence. Recurrent breast cancers arise from the pool of resid...
Plasma metabolomics profiles and breast cancer risk
Plasma metabolomics profiles and breast cancer risk
Breast cancer (BC) is the most common cancer in women and incidence rates are increasing; metabolomics may be a promising ...
Reproductive factors and mammographic density within the International Consortium of Mammographic Density: A cross-sectional study
Reproductive factors and mammographic density within the International Consortium of Mammographic Density: A cross-sectional study
Elevated mammographic density (MD) for a woman’s age and body mass index (BMI) is an established breast cancer risk ...
On-treatment biopsies to predict response to neoadjuvant chemotherapy for breast cancer
On-treatment biopsies to predict response to neoadjuvant chemotherapy for breast cancer
Patients with pathologic complete response (pCR) to neoadjuvant chemotherapy for invasive breast cancer (BC) have better o...
The deubiquitinating enzyme USP11 regulates breast cancer progression by stabilizing PGAM5
The deubiquitinating enzyme USP11 regulates breast cancer progression by stabilizing PGAM5
Breast cancer is common worldwide. Phosphoglycerate mutase 5 (PGAM5) belongs to the phosphoglycerate mutase family and pla...
Deep learning applications in breast cancer histopathological imaging: diagnosis, treatment, and prognosis
Deep learning applications in breast cancer histopathological imaging: diagnosis, treatment, and prognosis
Breast cancer is the most common malignant tumor among women worldwide and remains one of the leading causes of death amon...
Impact of an online decision support tool for ductal carcinoma in situ (DCIS) using a pre-post design (AFT-25)
Impact of an online decision support tool for ductal carcinoma in situ (DCIS) using a pre-post design (AFT-25)
The heterogeneous biology of ductal carcinoma in situ (DCIS), as well as the variable outcomes, in the setting of numerous...
Safety and efficacy of topical testosterone in breast cancer patients receiving ovarian suppression and aromatase inhibitor therapy
Safety and efficacy of topical testosterone in breast cancer patients receiving ovarian suppression and aromatase inhibitor therapy
Premenopausal, high-risk, hormone receptor-positive breast cancer patients are often treated with ovarian suppression in c...
A triple hormone receptor ER, AR, and VDR signature is a robust prognosis predictor in breast cancer
A triple hormone receptor ER, AR, and VDR signature is a robust prognosis predictor in breast cancer
Despite evidence indicating the dominance of cell-of-origin signatures in molecular tumor patterns, translating these geno...
CAR expression in invasive breast carcinoma and its effect on adenovirus transduction efficiency
CAR expression in invasive breast carcinoma and its effect on adenovirus transduction efficiency
Breast cancer is the second leading cause of death in women, with invasive ductal carcinoma (IDC) and invasive lobular car...
Single-cell transcriptional atlas of tumor-associated macrophages in breast cancer
Single-cell transcriptional atlas of tumor-associated macrophages in breast cancer
The internal heterogeneity of breast cancer, notably the tumor microenvironment (TME) consisting of malignant and non-mali...