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Evolution of breast cancer incidence in young women in a French registry from 1990 to 2018: Towards a change in screening strategy?
Evolution of breast cancer incidence in young women in a French registry from 1990 to 2018: Towards a change in screening strategy?
The worldwide incidence of invasive breast cancer in women is increasing according to several studies. This increase in in...
The bone–muscle connection in breast cancer: implications and therapeutic strategies to preserve musculoskeletal health
The bone–muscle connection in breast cancer: implications and therapeutic strategies to preserve musculoskeletal health
Breast cancer and its therapies frequently result in significant musculoskeletal morbidity. Skeletal complications include...
Correction: PredictCBC-2.0: a contralateral breast cancer risk prediction model developed and validated in ~ 200,000 patients
Correction: PredictCBC-2.0: a contralateral breast cancer risk prediction model developed and validated in ~ 200,000 patients
Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Plesmanlaan 121, 1066...
Androgen receptor function and targeted therapeutics across breast cancer subtypes
Androgen receptor function and targeted therapeutics across breast cancer subtypes
Despite significant progress in breast cancer (BC) therapy, it is globally the most commonly diagnosed cancer and leads to...
Birthweight, childhood body size, and timing of puberty and risks of breast cancer by menopausal status and tumor receptor subtypes
Birthweight, childhood body size, and timing of puberty and risks of breast cancer by menopausal status and tumor receptor subtypes
Associations of birthweight, childhood body size and pubertal timing with breast cancer risks by menopausal status and tum...
Matrix Gla protein (MGP), GATA3, and TRPS1: a novel diagnostic panel to determine breast origin
Matrix Gla protein (MGP), GATA3, and TRPS1: a novel diagnostic panel to determine breast origin
Metastatic breast carcinoma is commonly considered during differential diagnosis when metastatic disease is detected in fe...
Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment
Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment
The tumor immune microenvironment (TIME) generated by cancer-infiltrating immune cells has a crucial role in promoting or ...
RAB4A GTPase regulates epithelial-to-mesenchymal transition by modulating RAC1 activation
RAB4A GTPase regulates epithelial-to-mesenchymal transition by modulating RAC1 activation
Epithelial-to-mesenchymal transition (EMT) is a critical underpinning process for cancer progression, recurrence and resis...
Elevated NRAS expression during DCIS is a potential driver for progression to basal-like properties and local invasiveness
Elevated NRAS expression during DCIS is a potential driver for progression to basal-like properties and local invasiveness
Ductal carcinoma in situ (DCIS) is the most common type of in situ premalignant breast cancers. What drives DCIS to invasi...
High platelet-to-lymphocyte ratios in triple-negative breast cancer associates with immunosuppressive status of TILs
High platelet-to-lymphocyte ratios in triple-negative breast cancer associates with immunosuppressive status of TILs
Rating lymphocytes (TILs) are a prognostic marker in breast cancer and high TIL infiltration correlates with better patien...
Sex steroid hormones and risk of breast cancer: a two-sample Mendelian randomization study
Sex steroid hormones and risk of breast cancer: a two-sample Mendelian randomization study
Breast cancer (BC) has the highest cancer incidence and mortality in women worldwide. Observational epidemiological studie...
Breast cancer risk in papilloma patients: Osteopontin splice variants indicate prognosis
Breast cancer risk in papilloma patients: Osteopontin splice variants indicate prognosis
Papillomas of the breast pose challenges for treatment decisions as their risk for transformation to breast cancer is low ...
Krüppel-like factor 7 influences translation and pathways involved in ribosomal biogenesis in breast cancer
Krüppel-like factor 7 influences translation and pathways involved in ribosomal biogenesis in breast cancer
Ribosomal biogenesis and ribosomal proteins have attracted attention in the context of tumor biology in recent years. Inst...
Exosomal Wnt7a from a low metastatic subclone promotes lung metastasis of a highly metastatic subclone in the murine 4t1 breast cancer
Exosomal Wnt7a from a low metastatic subclone promotes lung metastasis of a highly metastatic subclone in the murine 4t1 breast cancer
Patients with triple-negative breast cancer (TNBC) often have poorer prognosis than those with other subtypes because of i...
Relationship between ER expression by IHC or mRNA with Ki67 response to aromatase inhibition: a POETIC study
Relationship between ER expression by IHC or mRNA with Ki67 response to aromatase inhibition: a POETIC study
In clinical practice, oestrogen receptor (ER) analysis is almost entirely by immunohistochemistry (IHC). ASCO/CAP recommen...
Methylation-based markers of aging and lifestyle-related factors and risk of breast cancer: a pooled analysis of four prospective studies
Methylation-based markers of aging and lifestyle-related factors and risk of breast cancer: a pooled analysis of four prospective studies
DNA methylation in blood may reflect adverse exposures accumulated over the lifetime and could therefore provide potential...
MiRNA expression deregulation correlates with the Oncotype DX® DCIS score
MiRNA expression deregulation correlates with the Oncotype DX® DCIS score
Current clinical criteria do not discriminate well between women who will or those who will not develop ipsilateral invasi...
Racial disparities in breast cancer preclinical and clinical models
Racial disparities in breast cancer preclinical and clinical models
Breast cancer (BCa) has long been a health burden to women across the globe. However, the burden is not equally carried ac...