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Use of Hormonal Contraceptives in Perimenopause: A Systematic Review
Use of Hormonal Contraceptives in Perimenopause: A Systematic Review
Abstract Introduction Hormonal contraceptives have been used in perimenopausal women to manage a variety of symptoms and p...
Use of naldemedine is associated with reduced incidence of hyperactive delirium in cancer patients with opioid‐induced constipation: a nationwide retrospective cohort study in Japan
Use of naldemedine is associated with reduced incidence of hyperactive delirium in cancer patients with opioid‐induced constipation: a nationwide retrospective cohort study in Japan
Abstract Background Medical benefits of peripherally-acting mu-opioid receptor antagonists other than improving opioid-ind...
Exploring the frontier of cardiovascular pharmacotherapy
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Role of maternal COVID‐19 vaccination in providing immunological protection to the newborn
Role of maternal COVID‐19 vaccination in providing immunological protection to the newborn
Abstract Pregnant and postpartum individuals are known to have an elevated risk of severe COVID-19 compared with their non...
Multi‐center retrospective study evaluating the efficacy and safety of apixaban versus warfarin for treatment of venous thromboembolism in patients with severe obesity
Multi‐center retrospective study evaluating the efficacy and safety of apixaban versus warfarin for treatment of venous thromboembolism in patients with severe obesity
Abstract Introduction Direct oral anticoagulants are the standard of care for venous thromboembolism (VTE) treatment. Thes...
Tacrolimus time in therapeutic range and long‐term outcomes in heart transplant recipients
Tacrolimus time in therapeutic range and long‐term outcomes in heart transplant recipients
Abstract Background Little is known about the association between tacrolimus time in therapeutic range (TTR) within the gu...
Dexmedetomidine for prevention of opioid/benzodiazepine withdrawal syndrome in pediatric intensive care unit: interim analysis of a randomized controlled trial
Dexmedetomidine for prevention of opioid/benzodiazepine withdrawal syndrome in pediatric intensive care unit: interim analysis of a randomized controlled trial
Abstract Introduction Withdrawal syndrome (WS) is a critical drawback of opioid/benzodiazepine weaning in children. The mo...
Anticholinergic medication burden and cognitive function in participants of the ASPREE study
Anticholinergic medication burden and cognitive function in participants of the ASPREE study
Abstract Introduction Exposure to anticholinergic medications may be associated with cognitive decline. Understanding whic...
Role of the Gut Microbiome in Cardiovascular Drug Response: The Potential for Clinical Application
Role of the Gut Microbiome in Cardiovascular Drug Response: The Potential for Clinical Application
Abstract Response to cardiovascular drugs can vary greatly between individuals, and the role of the microbiome in this var...
Apixaban and rivaroxaban use for atrial fibrillation in patients with obesity and BMI ≥50 kg/m2
Apixaban and rivaroxaban use for atrial fibrillation in patients with obesity and BMI ≥50 kg/m2
Abstract Background Apixaban and rivaroxaban are increasingly used for thromboembolism prophylaxis in patients with nonval...
The role of maternal COVID‐19 vaccination in providing immunological protection to the newborn
The role of maternal COVID‐19 vaccination in providing immunological protection to the newborn
Abstract Pregnant and postpartum individuals are known to have an elevated risk of severe COVID-19 compared to their non-p...
Chemotherapy‐associated cardiomyopathy: Mechanisms of toxicity and cardioprotective strategies
Chemotherapy‐associated cardiomyopathy: Mechanisms of toxicity and cardioprotective strategies
Abstract Objective To describe the proposed mechanisms of chemotherapy-associated cardiomyopathy (CAC) and potential cardi...
A prospective study of filgrastim pharmacokinetics in morbidly obese patients compared with non‐obese controls
A prospective study of filgrastim pharmacokinetics in morbidly obese patients compared with non‐obese controls
Abstract Introduction Filgrastim is a human granulocyte colony-stimulating factor (G-CSF). There are limited data on dosin...
Clinical Impact of GLP‐1 Receptor Agonists in Veterans Receiving Basal‐Bolus Insulin
Clinical Impact of GLP‐1 Receptor Agonists in Veterans Receiving Basal‐Bolus Insulin
ABSTRACT Background In 2017 an estimated 7.4 million Americans used insulin to treat diabetes. Insulin is proven to lower ...
A Prospective Study of Filgrastim Pharmacokinetics in Morbidly Obese Patients Compared to Non‐Obese Controls
A Prospective Study of Filgrastim Pharmacokinetics in Morbidly Obese Patients Compared to Non‐Obese Controls
ABSTRACT Introduction Filgrastim is a human granulocyte colony-stimulating factor (G-CSF). There is limited data on dosing...
Association of CYP2B6 genetic polymorphisms with bupropion and hydroxybupropion exposure: A systematic review and meta‐analysis
Association of CYP2B6 genetic polymorphisms with bupropion and hydroxybupropion exposure: A systematic review and meta‐analysis
Abstract Introduction Bupropion is metabolized to its active metabolite, hydroxybupropion (HB), by the genetically polymor...
The role of tazobactam‐based combinations for the management of infections due to extended‐spectrum β‐lactamase‐producing Enterobacterales: Insights from the Society of Infectious Diseases Pharmacists
The role of tazobactam‐based combinations for the management of infections due to extended‐spectrum β‐lactamase‐producing Enterobacterales: Insights from the Society of Infectious Diseases Pharmacists
Abstract Extended-spectrum β-lactamase (ESBL)-producing Enterobacterales are a global threat to public health due to...
Early clinical trial data and real‐world assessment of COVID‐19 vaccines: Insights from the Society of Infectious Diseases Pharmacists
Early clinical trial data and real‐world assessment of COVID‐19 vaccines: Insights from the Society of Infectious Diseases Pharmacists
Abstract As of August 2021, there were three COVID-19 vaccines available in the United States for the prevention of corona...
Alemtuzumab Clearance, Lymphocyte Count, and T‐Cell Chimerism After Hematopoietic Stem Cell Transplant in Sickle Cell Disease
Alemtuzumab Clearance, Lymphocyte Count, and T‐Cell Chimerism After Hematopoietic Stem Cell Transplant in Sickle Cell Disease
Abstract INTRODUCTION Alemtuzumab is a monoclonal antibody that targets the cell surface antigen CD52 on lymphocytes. Alth...
Advances in the Treatment of Transthyretin Cardiac Amyloidosis: Current and Emerging Therapies
Advances in the Treatment of Transthyretin Cardiac Amyloidosis: Current and Emerging Therapies
Abstract Transthyretin cardiac amyloidosis (ATTR-CA) has been recognized as an underdiagnosed and undertreated cause of he...
Current Pharmacotherapy Management of Children and Adults with Pericarditis: Prospectus for Improved Outcomes
Current Pharmacotherapy Management of Children and Adults with Pericarditis: Prospectus for Improved Outcomes
Abstract Pericarditis is the most common inflammatory pericardial disease in both children and adults. Since the publicati...
Comparison of Risk‐Scoring Systems for Heparin‐Induced Thrombocytopenia in Cardiac Surgery Patients
Comparison of Risk‐Scoring Systems for Heparin‐Induced Thrombocytopenia in Cardiac Surgery Patients
ABSTRACT Objectives Several risk-scoring tools have been developed to exclude heparin-induced thrombocytopenia (HIT) in pa...
Association of Bleeding with Serotonergic Antidepressants in Patients Receiving Left Ventricular Assist Device Support
Association of Bleeding with Serotonergic Antidepressants in Patients Receiving Left Ventricular Assist Device Support
ABSTRACT Background Bleeding events are common in patients receiving continuous flow left ventricular assist device (CF-LV...
Cardiovascular and Kidney Outcomes of Spironolactone or Eplerenone in Combination with ACEI/ARBs in Patients with Diabetic Kidney Disease
Cardiovascular and Kidney Outcomes of Spironolactone or Eplerenone in Combination with ACEI/ARBs in Patients with Diabetic Kidney Disease
Abstract Background Mineralocorticoid receptor antagonist (MRA) when combined with either angiotensin-converting enzyme in...
Population Pharmacokinetic Model‐guided Optimization of Intravenous Voriconazole Dosing Regimens in Critically Ill Patients with Liver Dysfunction
Population Pharmacokinetic Model‐guided Optimization of Intravenous Voriconazole Dosing Regimens in Critically Ill Patients with Liver Dysfunction
Abstract Objectives This prospective study aimed to establish a population pharmacokinetic (PPK) model of intravenous vori...
Meta‐Analysis of Clinical Outcomes of PCSK9 Modulators in Patients with Established ASCVD
Meta‐Analysis of Clinical Outcomes of PCSK9 Modulators in Patients with Established ASCVD
Abstract Background The advent of monoclonal antibodies targeting proprotein convertase subtilisin/kexin type 9 (PCSK9) us...
Corticosteroid use in ARDS and its Application to Evolving Therapeutics for Coronavirus Disease 2019 (COVID‐19): A Systematic Review
Corticosteroid use in ARDS and its Application to Evolving Therapeutics for Coronavirus Disease 2019 (COVID‐19): A Systematic Review
Abstract Data regarding the use of corticosteroids for treatment of acute respiratory distress syndrome (ARDS) are conflic...
Open‐Source Maximum a Posteriori‐Bayesian Dosing AdDS to Current Therapeutic Drug Monitoring: Adapting to the Era of Individualized Therapy
Open‐Source Maximum a Posteriori‐Bayesian Dosing AdDS to Current Therapeutic Drug Monitoring: Adapting to the Era of Individualized Therapy
Abstract Recent updates in the therapeutic drug monitoring (TDM) guidelines for vancomycin has rekindled interest in maxim...
Management of Diffuse Alveolar Hemorrhage in the Hematopoietic Stem Cell Transplantation Population: A Systematic Review
Management of Diffuse Alveolar Hemorrhage in the Hematopoietic Stem Cell Transplantation Population: A Systematic Review
Abstract Pulmonary complications post hematopoietic stem cell transplantation (HSCT) such as diffuse alveolar hemorrhage (...
Optimizing Anticoagulation for Patients Receiving Impella Support
Optimizing Anticoagulation for Patients Receiving Impella Support
Abstract Anticoagulation of patients treated with the Impella percutaneous mechanical circulatory support (MCS) devices is...
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