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Language is widely distributed throughout the brain
Thus, despite the large number of studies using the ‘language localizer’ approach, results do not necessarily constitute e...
The short and long pathways to memory
Inhibition of CaMKII blocks short-term memory but not long-term memory of inhibitory avoidance in mice.
Circuit control of competition
A study explores the circuits through which the dorsolateral prefrontal cortex orchestrates social competition in mice.
Neural compositions use multigoal building blocks
A new study reveals an algorithm implemented by neurons in the medial frontal cortex that is involved in flexibly mapping ...
Schemas, reinforcement learning and the medial prefrontal cortex
Schemas, reinforcement learning and the medial prefrontal cortex
Schemas are rich and complex knowledge structures about the typical unfolding of events in a context; for example, a schem...
The curious case of dopaminergic prediction errors and learning associative information beyond value
The curious case of dopaminergic prediction errors and learning associative information beyond value
Transient changes in the firing of midbrain dopamine neurons have been closely tied to the unidimensional value-based pred...
Endothelial cells as key players in cerebral small vessel disease
Endothelial cells as key players in cerebral small vessel disease
Cerebral small vessel disease (SVD) is a vascular disorder that increases the risk of stroke and dementia and is diagnosed...
The brain’s action-mode network
The brain’s action-mode network
The brain is always intrinsically active, using energy at high rates while cycling through global functional modes. Awake ...
When the ‘selfish’ brain and the ‘selfish’ immune system clash
In this Journal Club, Michaela Fencková discusses a study published in 2020 that examined the effects of acute system...
Reply to ‘The core language network separated from other networks during primate evolution’
Reply to ‘The core language network separated from other networks during primate evolution’
Fedorenko, E., Ivanova, A. A. & Regev, T. I. The language network as a natural kind within the broader landscape of th...
An unexpected role for macrophages in motor control
A population of macrophages has been found in muscle spindles that release glutamate, activate primary sensory afferents t...
Publisher Correction: Structural neural plasticity evoked by rapid-acting antidepressant interventions
Publisher Correction: Structural neural plasticity evoked by rapid-acting antidepressant interventions
Authors and AffiliationsMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY, USAClara Liao, Cassandra ...
Metastability demystified — the foundational past, the pragmatic present and the promising future
Metastability demystified — the foundational past, the pragmatic present and the promising future
Healthy brain function depends on balancing stable integration between brain areas for effective coordinated functioning, ...
Structurally informed models of directed brain connectivity
Structurally informed models of directed brain connectivity
Understanding how one brain region exerts influence over another in vivo is profoundly constrained by models used to infer...
Remission from addiction: erasing the wrong circuits or making new ones?
Remission from addiction: erasing the wrong circuits or making new ones?
Chronic relapse is a hallmark of substance-use disorders (SUDs), but many people with SUDs do recover and eventually enter...
Understanding the molecular diversity of synapses
Understanding the molecular diversity of synapses
Synapses are composed of thousands of proteins, providing the potential for extensive molecular diversity to shape synapse...
Targeting TYK2 to target tau
Studies in human cell lines and transgenic mouse models show that non-receptor tyrosine-protein kinase TYK2 phosphorylates...
Structural MRI of brain similarity networks
Structural MRI of brain similarity networks
Recent advances in structural MRI analytics now allow the network organization of individual brains to be comprehensively ...
Neural circuit basis of pathological anxiety
Neural circuit basis of pathological anxiety
Anxiety disorders are the most prevalent mental health conditions worldwide. Unfortunately, the understanding of the preci...
Echolocation over long distances
Bats use echolocation to navigate long distances without relying on other sensory information.
An interoceptive circuit regulating energy balance
Interoceptive, feeding-related inputs are integrated by BDNF-expressing neurons in the ventromedial hypothalamus that proj...
Ruminating on replay during the awake state
In this Journal Club, Anna Gillespie discusses how the discovery of hippocampal replay during the awake state reshaped our...
Innate immune control of synapse development
Innate lymphoid cells regulate inhibitory synapse formation in the mouse cortex during early postnatal life.
Structural neural plasticity evoked by rapid-acting antidepressant interventions
Structural neural plasticity evoked by rapid-acting antidepressant interventions
A feature in the pathophysiology of major depressive disorder (MDD), a mood disorder, is the impairment of excita...
Issues of parcellation in the calculation of structure–function coupling
In their recent Review, Fotiadis and colleagues expertly summarized recent research on structure–func...
Reply to ‘Issues of parcellation in the calculation of structure–function coupling’
We appreciate the thoughtful Correspondence from A. Turnbull, F. V. Lin and Z. Zhang about our recent...
A new target for leptin
Tan et al. identify a population of leptin-responsive neurons that regulate food intake and body weight.
Neurobiology of attention-deficit hyperactivity disorder: historical challenges and emerging frontiers
Neurobiology of attention-deficit hyperactivity disorder: historical challenges and emerging frontiers
Extensive investigations spanning multiple levels of inquiry, from genetic to behavioural studies, have sought to unravel ...