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The origins of freezing
Philip Tovote describes the 1980 paper in which Michael Fanselow systematically investigated freezing as a defensive respo...
Disentangling human inference
A study in humans reveals that the hippocampus encodes relevant task variables in abstract format during inferential reaso...
Mapping future locations
Study identifies 'predictive grid cells' in the rat entorhinal cortex that encode projected future locations.
Thyroid hormone modulates exploration circuits
Thyroid hormone induces cortical circuit plasticity to modulate exploratory behaviours in mice.
Neural control of gut regulatory T cells
Activation of nociceptor neurons expressing TRPV1 downregulates gut regulatory T cells.
Astrocyte antennae
Most astrocytes in the mouse brain have a primary cilium that transduces local cues to drive distinct astrocytic transcrip...
Advances in the labelling and selective manipulation of synapses
Advances in the labelling and selective manipulation of synapses
Synapses are highly specialized neuronal structures that are essential for neurotransmission, and they are dynamically reg...
Neuronal maturation and axon regeneration: unfixing circuitry to enable repair
Neuronal maturation and axon regeneration: unfixing circuitry to enable repair
Mammalian neurons lose the ability to regenerate their central nervous system axons as they mature during embryonic or ear...
Reply to ‘The language network is topographically diverse and driven by rapid syntactic inferences’
We thank Murphy and Woolnough for their comments on our recent Review (Fedorenko, E., Ivanova, A. A, ...
The language network is topographically diverse and driven by rapid syntactic inferences
In their timely Review article, Fedorenko and colleagues highlight how the posterior temporal cortex ...
Structure–function coupling in macroscale human brain networks
Structure–function coupling in macroscale human brain networks
Precisely how the anatomical structure of the brain gives rise to a repertoire of complex functions remains incompletely u...
Circuit refinement without microglia
A study finds that microglia depletion has no effect on experience-dependent maturation of visual cortex circuitry in mice.
Multi-timescale neural dynamics for multisensory integration
Multi-timescale neural dynamics for multisensory integration
Carrying out any everyday task, be it driving in traffic, conversing with friends or playing basketball, requires rapid se...
Variants in a noncoding gene drive prevalent neurodevelopmental disorder
Two studies use large-scale genome sequencing data to identify variants in a noncoding gene that cause a neurodevelopmenta...
Psilocybin desynchronization persists in the human brain
Longitudinal precision functional mapping reveals that acute desynchronization of functional connectivity organization ind...
Thirsty work for the cerebellum
Cerebellar Purkinje neurons modulate thirst in mice
Indirect neurogenesis in space and time
Indirect neurogenesis in space and time
During central nervous system (CNS) development, neural progenitor cells (NPCs) generate neurons and glia in two different...
Publisher Correction: Macroscopic gradients of synaptic excitation and inhibition in the neocortex
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obta...
Schizophrenia genomics: genetic complexity and functional insights
Schizophrenia genomics: genetic complexity and functional insights
Determining the causes of schizophrenia has been a notoriously intractable problem, resistant to a multitude of investigat...
Neurogenic exacerbation of psoriasis
Acid-sensing ion channel 3 in nociceptors exacerbates inflammation in psoriasis by inducing the release of calcitonin gene...
Mapping the cell-type-specific effects of ageing in the human cortex
A study maps the effects of ageing and sex on gene regulation in specific human cortical cell types.
Wrapping up reward
The maladaptive reward learning associated with morphine administration is shown here to be mediated by changes in dopamin...
Predicting natural behaviour by perturbation
A new modelling method developed in male Drosophila melanogaster maps how populations of neurons transform visual stimuli ...
Why so slow? Models of parkinsonian bradykinesia
Why so slow? Models of parkinsonian bradykinesia
Bradykinesia, or slowness of movement, is a defining feature of Parkinson disease (PD) and a major contributor to the nega...
Timescales of learning in prefrontal cortex
Timescales of learning in prefrontal cortex
The lateral prefrontal cortex (PFC) in humans and other primates is critical for immediate, goal-directed behaviour and wo...
Causal prominence for neuroscience
When is a causal system explanatory enough to be termed a ‘mechanism’? In their recent Review, Ross a...
The power of direct observation: discovery of REM sleep
In this Journal Club, Danqian Liu describes the 1953 paper that reported the discovery of rapid eye movement (REM) sleep.
Reply to ‘Causal prominence for neuroscience’
In our recent Review (Ross, L. N. & Bassett, D. S. Causation in neuroscience: keeping mechanism m...
Gene therapy for CNS disorders: modalities, delivery and translational challenges
Gene therapy for CNS disorders: modalities, delivery and translational challenges
Gene therapy is emerging as a powerful tool to modulate abnormal gene expression, a hallmark of most CNS disorders. The tr...
Fear, anxiety and the functional architecture of the human central extended amygdala
Fear, anxiety and the functional architecture of the human central extended amygdala
The authors acknowledge assistance and critical feedback from B. Cornwell, L. Friedman, J. Hur, C. Kaplan, H. Kim, M. Kuhn...
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