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Innate immune control of synapse development
Innate lymphoid cells regulate inhibitory synapse formation in the mouse cortex during early postnatal life.
Structural neural plasticity evoked by rapid-acting antidepressant interventions
Structural neural plasticity evoked by rapid-acting antidepressant interventions
A feature in the pathophysiology of major depressive disorder (MDD), a mood disorder, is the impairment of excita...
Issues of parcellation in the calculation of structure–function coupling
In their recent Review, Fotiadis and colleagues expertly summarized recent research on structure–func...
Reply to ‘Issues of parcellation in the calculation of structure–function coupling’
We appreciate the thoughtful Correspondence from A. Turnbull, F. V. Lin and Z. Zhang about our recent...
A new target for leptin
Tan et al. identify a population of leptin-responsive neurons that regulate food intake and body weight.
Neurobiology of attention-deficit hyperactivity disorder: historical challenges and emerging frontiers
Neurobiology of attention-deficit hyperactivity disorder: historical challenges and emerging frontiers
Extensive investigations spanning multiple levels of inquiry, from genetic to behavioural studies, have sought to unravel ...
Opening the gate to regeneration
After injury, regeneration of retinal ganglion cells and reconnection to their original target — the suprachiasmatic...
Fly connectome over the wire
A series of papers provide an overview of the adult Drosophila melanogaster whole-brain connectome and how the resulting r...
Social and emotional learning in the cerebellum
Social and emotional learning in the cerebellum
The posterior cerebellum has a critical role in human social and emotional learning. Three systems and related neural netw...
Synaptic sleep pressure
Manipulating the synaptic strength of cortical neurons alters sleep pressure in mice.
A roadmap towards standardized neuroimaging approaches for human thalamic nuclei
A roadmap towards standardized neuroimaging approaches for human thalamic nuclei
The thalamus has a key role in mediating cortical–subcortical interactions but is often neglected in neuroimaging st...
How can ethology inform the neuroscience of fear, aggression and dominance?
How can ethology inform the neuroscience of fear, aggression and dominance?
The study of behaviour is dominated by two approaches. On the one hand, ethologists aim to understand how behaviour promot...
Consequences of trisomy 21 for brain development in Down syndrome
Consequences of trisomy 21 for brain development in Down syndrome
The appearance of cognitive deficits and altered brain morphology in newborns with Down syndrome (DS) suggests that these ...
RNA granules in flux: dynamics to balance physiology and pathology
RNA granules in flux: dynamics to balance physiology and pathology
The life cycle of an mRNA is a complex process that is tightly regulated by interactions between the mRNA and RNA-binding ...
Pericyte relaxation boosts cerebral blood flow
Blocking voltage-gated calcium channels reduces capillary narrowing by pericytes and improves cerebral blood flow in a mou...
Genetically defined neuron types underlying visuomotor transformation in the superior colliculus
Genetically defined neuron types underlying visuomotor transformation in the superior colliculus
The superior colliculus (SC) is a conserved midbrain structure that is important for transforming visual and other sensory...
Thicker perineuronal nets disrupt insulin signalling
Diet-induced obesity in mice is accompanied by hypothalamic inflammation, which is shown here to result in thickened perin...
Safety in numbers
An anterior cingulate cortex to lateral septum circuit underlies the drive of spiny mice to affiliate with larger groups i...
How witnessing distress alters resilience
Mice that witness a cage mate’s distress become resilient to future adverse events as a result of altered serotonin ...
Concept cells and social memory: the abstract representation of familiar individuals
In this Journal club, Teruhiro Okuyama discusses the 2005 article that demonstrated the existence of ‘concept cells&...
The origins of freezing
Philip Tovote describes the 1980 paper in which Michael Fanselow systematically investigated freezing as a defensive respo...
Disentangling human inference
A study in humans reveals that the hippocampus encodes relevant task variables in abstract format during inferential reaso...
Mapping future locations
Study identifies 'predictive grid cells' in the rat entorhinal cortex that encode projected future locations.
Thyroid hormone modulates exploration circuits
Thyroid hormone induces cortical circuit plasticity to modulate exploratory behaviours in mice.
Neural control of gut regulatory T cells
Activation of nociceptor neurons expressing TRPV1 downregulates gut regulatory T cells.
Astrocyte antennae
Most astrocytes in the mouse brain have a primary cilium that transduces local cues to drive distinct astrocytic transcrip...
Advances in the labelling and selective manipulation of synapses
Advances in the labelling and selective manipulation of synapses
Synapses are highly specialized neuronal structures that are essential for neurotransmission, and they are dynamically reg...
Neuronal maturation and axon regeneration: unfixing circuitry to enable repair
Neuronal maturation and axon regeneration: unfixing circuitry to enable repair
Mammalian neurons lose the ability to regenerate their central nervous system axons as they mature during embryonic or ear...
Reply to ‘The language network is topographically diverse and driven by rapid syntactic inferences’
We thank Murphy and Woolnough for their comments on our recent Review (Fedorenko, E., Ivanova, A. A, ...
The language network is topographically diverse and driven by rapid syntactic inferences
In their timely Review article, Fedorenko and colleagues highlight how the posterior temporal cortex ...
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