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Real‐world effectiveness of anti‐resorptive treatment in patients with incident fragility fractures – The STORM cohort – A Swedish retrospective observational study
Real‐world effectiveness of anti‐resorptive treatment in patients with incident fragility fractures – The STORM cohort – A Swedish retrospective observational study
ABSTRACT Results from real-world evidence (RWE) from the largest healthcare region in Sweden show low uptake of antiresorp...
A Perspective on Postmenopausal Bone Loss with Aging
A Perspective on Postmenopausal Bone Loss with Aging
Corresponding Author Karin C Wu Department of Medicine, Un...
Bone Geometry, Density, Microstructure, and Biomechanical Properties in the Distal Tibia in Patients With Primary Hypertrophic Osteoarthropathy Assessed by Second‐Generation High‐Resolution Peripheral Quantitative Computed Tomography
Bone Geometry, Density, Microstructure, and Biomechanical Properties in the Distal Tibia in Patients With Primary Hypertrophic Osteoarthropathy Assessed by Second‐Generation High‐Resolution Peripheral Quantitative Computed Tomography
ABSTRACT Periosteosis refers to pathological woven bone formation beneath the cortical bone of the long bones. It is an im...
Bone Microarchitecture in Transgender Adults: a Cross Sectional Study
Bone Microarchitecture in Transgender Adults: a Cross Sectional Study
Abstract Gender-affirming hormone therapy aligns physical characteristics with an individual's gender identity, but sex ho...
Myeloid‐Specific PTP1B Deficiency Attenuates Inflammation‐Induced and Ovariectomy‐Induced Bone Loss in Mice by Inhibiting Osteoclastogenesis
Myeloid‐Specific PTP1B Deficiency Attenuates Inflammation‐Induced and Ovariectomy‐Induced Bone Loss in Mice by Inhibiting Osteoclastogenesis
ABSTRACT The differentiation and activity of bone-resorbing osteoclasts are tightly regulated to maintain the homeostasis ...
Bone‐targeted Bortezomib Inhibits Bortezomib‐Resistant Multiple Myeloma in Mice by Providing Higher Levels of Bortezomib in Bone
Bone‐targeted Bortezomib Inhibits Bortezomib‐Resistant Multiple Myeloma in Mice by Providing Higher Levels of Bortezomib in Bone
Abstract Limited treatment options exist for cancer within the bone, as demonstrated by the inevitable, pernicious course ...
Short Cyclic Regimen with Parathyroid Hormone (PTH) Results in Prolonged Anabolic Effect Relative to Continuous Treatment Followed by Discontinuation in Ovariectomized Rats
Short Cyclic Regimen with Parathyroid Hormone (PTH) Results in Prolonged Anabolic Effect Relative to Continuous Treatment Followed by Discontinuation in Ovariectomized Rats
ABSTRACT Despite the potent effect of intermittent PTH treatment on promoting new bone formation, BMD rapidly decreases up...
Bone microarchitecture phenotypes identified in older adults are associated with different levels of osteoporotic fracture risk
Bone microarchitecture phenotypes identified in older adults are associated with different levels of osteoporotic fracture risk
ABSTRACT Prevalence of osteoporosis is over 50% in older adults, yet current clinical methods for diagnosis that rely on a...
Plasma Soluble Biomarkers for Fibrodysplasia Ossificans Progressiva (FOP) Reflect Acute and Chronic Inflammatory States
Plasma Soluble Biomarkers for Fibrodysplasia Ossificans Progressiva (FOP) Reflect Acute and Chronic Inflammatory States
Abstract Fibrodysplasia Ossificans Progressiva (FOP) is a progressive, debilitating genetic disease in which skeletal musc...
Efficacy of Zoledronic Acid in the Treatment of Non‐malignant Painful Bone Mar‐row Lesions: A Triple‐Blind, Randomized, Placebo‐Controlled Phase III Clinical Trial (ZoMARS)
Efficacy of Zoledronic Acid in the Treatment of Non‐malignant Painful Bone Mar‐row Lesions: A Triple‐Blind, Randomized, Placebo‐Controlled Phase III Clinical Trial (ZoMARS)
Abstract Bone marrow lesions (BML) represent areas of deteriorated bone structure and metabolism characterized by pronounc...
Genes with specificity for expression in the round cell layer of the growth plate are enriched in genomewide association study (GWAS) of human height
Genes with specificity for expression in the round cell layer of the growth plate are enriched in genomewide association study (GWAS) of human height
ABSTRACT Human adult height reflects the outcome of childhood skeletal growth. Growth plate (epiphyseal) chondrocytes are ...
JBMR Reviewer List 2021
JBMR Reviewer List 2021
The ASBMR and the journal Editors are incredibly thankful for the reviewers who volunteer their time for the vital mentori...
Re: “Hip Fracture and Mortality: A Loss of Life Expectancy Interpretation” by Thao T Ho‐Le and Tuan V Nguyen
Re: “Hip Fracture and Mortality: A Loss of Life Expectancy Interpretation” by Thao T Ho‐Le and Tuan V Nguyen
Volume 36, Issue 12 p. 2459-2460 Reply Letter to the Editor Cecilie Dahl, Correspondi...
Journal of Bone and Mineral Research: Volume 36, Number 12, December 2021
Journal of Bone and Mineral Research: Volume 36, Number 12, December 2021
Volume 36, Issue 12 p. C1-C1 PDF ShareShare P...
Burosumab for Tumor‐Induced Osteomalacia: Not Enough of a Good Thing
Burosumab for Tumor‐Induced Osteomalacia: Not Enough of a Good Thing
Volume 36, Issue 12 p. 2453-2454 Letter to the Editor Iris R Hartley, Iris R Hartley ...
Reply to: Burosumab for Tumor‐Induced Osteomalacia: not Enough of a Good Thing
Reply to: Burosumab for Tumor‐Induced Osteomalacia: not Enough of a Good Thing
We appreciate that Dr Hartley and Dr Collins recognize the importance of burosumab as a treatment for patients with tumor-...
Shared genetic architecture between rheumatoid arthritis and varying osteoporotic phenotypes
Shared genetic architecture between rheumatoid arthritis and varying osteoporotic phenotypes
Abstract Rheumatoid arthritis (RA) and low bone mineral density (BMD), an indicator of osteoporosis (OP), appear epidemiol...
Consider the bisphosphonate dose
Consider the bisphosphonate dose
PDF ShareShare Please review our Terms and Conditions of Use...
RANKL Blockade Reduces Cachexia and Bone Loss Induced by Non‐Metastatic Ovarian Cancer in Mice
RANKL Blockade Reduces Cachexia and Bone Loss Induced by Non‐Metastatic Ovarian Cancer in Mice
ABSTRACT Tumor- and bone-derived soluble factors have been proposed to participate in the alterations of skeletal muscle s...
Novel pathogenetic variants in PTHLH and TRPS1 genes causing syndromic brachydactyly
Novel pathogenetic variants in PTHLH and TRPS1 genes causing syndromic brachydactyly
ABSTRACT Skeletal disorders, including both isolated and syndromic brachydactyly type E, derive from genetic defects affec...
Immune Response to Persistent Staphyloccocus aureus Periprosthetic Joint Infection in a Mouse Tibial Implant Model
Immune Response to Persistent Staphyloccocus aureus Periprosthetic Joint Infection in a Mouse Tibial Implant Model
Abstract S. aureus is one of the major pathogens in orthopedic periprosthetic joint infection (PJI), a devastating complic...
Musculoskeletal comorbidities and quality of life in ENPP1‐deficient adults and the response of enthesopathy to enzyme replacement therapy in murine models
Musculoskeletal comorbidities and quality of life in ENPP1‐deficient adults and the response of enthesopathy to enzyme replacement therapy in murine models
Abstract Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) Deficiency leads to cardiovascular calcification in in...
Bone Geometry, Density, Microstructure and Biomechanical Properties in the Distal Tibia in Patients with Primary Hypertrophic Osteoarthropathy Assessed by Second‐Generation HR‐pQCT
Bone Geometry, Density, Microstructure and Biomechanical Properties in the Distal Tibia in Patients with Primary Hypertrophic Osteoarthropathy Assessed by Second‐Generation HR‐pQCT
Abstract Periosteosis refers to pathological woven bone formation beneath the cortical bone of the long bones. It is an im...
STAT3 hyperactivation due to SOCS3 deletion in murine osteocytes accentuates responses to exercise‐ and load‐induced bone formation
STAT3 hyperactivation due to SOCS3 deletion in murine osteocytes accentuates responses to exercise‐ and load‐induced bone formation
Abstract Cortical bone develops and changes in response to mechanical load, which is sensed by bone-embedded osteocytes. T...
Hedgehog signaling controls bone homeostasis by regulating osteogenic/adipogenic fate of skeletal stem/progenitor cells in mice
Hedgehog signaling controls bone homeostasis by regulating osteogenic/adipogenic fate of skeletal stem/progenitor cells in mice
Abstract Skeletal stem/progenitor cells (SSPCs) can differentiate into osteogenic or adipogenic lineage. The mechanism gov...
An expert perspective on phosphate dysregulation with a focus on chronic hypophosphatemia
An expert perspective on phosphate dysregulation with a focus on chronic hypophosphatemia
Abstract Due to their rarity, diseases characterized by chronic hypophosphatemia can be under-recognized and suboptimally ...
Muscle Strength and Physical Performance Improve Fracture Risk Prediction beyond Garvan and FRAX: The Osteoporotic Fractures in Men (MrOS) Study
Muscle Strength and Physical Performance Improve Fracture Risk Prediction beyond Garvan and FRAX: The Osteoporotic Fractures in Men (MrOS) Study
Abstract Muscle strength and physical performance are associated with fracture risk in men. However, it is not known wheth...
Interleukin‐1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification
Interleukin‐1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification
Abstract Neurogenic heterotopic ossifications (NHOs) form in periarticular muscles following severe spinal cord (SCI) and ...
Introduction of a Cys360Tyr Mutation in ANO5 Creates a Mouse Model for Gnathodiaphyseal Dysplasia
Introduction of a Cys360Tyr Mutation in ANO5 Creates a Mouse Model for Gnathodiaphyseal Dysplasia
Abstract Gnathodiaphyseal dysplasia (GDD) is a rare autosomal dominant genetic disease characterized by the osteosclerosis...
Greater Carboxy‐Methyl‐Lysine Is Associated With Increased Fracture Risk in Type 2 Diabetes
Greater Carboxy‐Methyl‐Lysine Is Associated With Increased Fracture Risk in Type 2 Diabetes
ABSTRACT Accumulation of advanced glycation end-products (AGE) in bone alters collagen structure and function. Fluorescent...
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