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Extracellular vesicle–based drug delivery in cancer immunotherapy
Extracellular vesicle–based drug delivery in cancer immunotherapy
Extracellular vesicles (EVs) are a group of nanoscale membrane-bound organelles including exosomes, microvesicles (MVs), m...
Lipid-based nanoparticle-mediated combination therapy for breast cancer management: a comprehensive review
Lipid-based nanoparticle-mediated combination therapy for breast cancer management: a comprehensive review
Breast cancer due to the unpredictable and complex etiopathology combined with the non-availability of any effective drug ...
Nanoengineered drug delivery in cancer immunotherapy for overcoming immunosuppressive tumor microenvironment
Nanoengineered drug delivery in cancer immunotherapy for overcoming immunosuppressive tumor microenvironment
Almost like a living being in and of itself, tumors actively interact with and modify their environment to escape immune r...
Nanomaterials for antigen-specific immune tolerance therapy
Nanomaterials for antigen-specific immune tolerance therapy
Impairment of immune tolerance might cause autologous tissue damage or overactive immune response against non-pathogenic m...
Nanoparticle pre-treatment for enhancing the survival and activation of pulmonary macrophage transplant
Nanoparticle pre-treatment for enhancing the survival and activation of pulmonary macrophage transplant
Despite recent clinical successes of chimeric antigen receptor T cell therapies in treating liquid cancers, many lingering...
Vaccines prevent reinduction of rheumatoid arthritis symptoms in collagen-induced arthritis mouse model
Vaccines prevent reinduction of rheumatoid arthritis symptoms in collagen-induced arthritis mouse model
Metabolic reprogramming of immune cells modulates their function and reduces the severity of autoimmune diseases. However,...
Neutrophils and neutrophil extracellular traps in cancer: promising targets for engineered nanomaterials
Neutrophils and neutrophil extracellular traps in cancer: promising targets for engineered nanomaterials
Neutrophils are the most abundant white blood cells in circulation and constitute up to 60% of circulating leukocytes. Neu...
Nanocarriers for cancer nano-immunotherapy
Nanocarriers for cancer nano-immunotherapy
The host immune system possesses an intrinsic ability to target and kill cancer cells in a specific and adaptable manner t...
Emerging immunotherapeutics for immune activation and tolerance
Emerging immunotherapeutics for immune activation and tolerance
Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine Street, Baltimore, MD, 21201,...
Short-chain fatty acid-mediated epigenetic modulation of inflammatory T cells in vitro
Short-chain fatty acid-mediated epigenetic modulation of inflammatory T cells in vitro
Short-chain fatty acids (SCFAs) are major metabolic products of indigestible polysaccharides in the gut and mediate the fu...
Mannose-modified hyaluronic acid nanocapsules for the targeting of tumor-associated macrophages
Mannose-modified hyaluronic acid nanocapsules for the targeting of tumor-associated macrophages
Tumor-associated macrophages (TAMs), a class of immune cells that play a key role in tumor immunosuppression, are recogniz...
Innate immune regulations and various siRNA modalities
Innate immune regulations and various siRNA modalities
RNAi therapeutics are designed to produce the precise silencing effects against the gene-linked diseases which were known ...
Regulatory aspects of a nanomaterial for imaging therapeutic cells
Regulatory aspects of a nanomaterial for imaging therapeutic cells
The ability to track therapeutic cells upon administration to the patient is of interest to both regulators and developers...
Atorvastatin liposomes in a 3D-printed polymer film: a repurposing approach for local treatment of oral candidiasis
Atorvastatin liposomes in a 3D-printed polymer film: a repurposing approach for local treatment of oral candidiasis
Oral candidiasis (OC) is an opportunistic fungal infection, common amongst the elderly and the immunocompromised. Unfortun...
Targeted delivery of budesonide in acetic acid induced colitis: impact on miR-21 and E-cadherin expression
Targeted delivery of budesonide in acetic acid induced colitis: impact on miR-21 and E-cadherin expression
Inflammatory bowel disease (IBD) is characterized by chronic inflammation along the gastrointestinal tract. For IBD effect...
Engineered lipid liquid crystalline nanoparticles as an inhaled nanoplatform for mucus penetration enhancement
Engineered lipid liquid crystalline nanoparticles as an inhaled nanoplatform for mucus penetration enhancement
Nanocarrier-assisted pulmonary drug delivery system has been widely employed for lung local disease treatment due to its e...
Construction and evaluation of a phospholipid-based phase transition in situ gel system for brexpiprazole
Construction and evaluation of a phospholipid-based phase transition in situ gel system for brexpiprazole
The objective of this study was to develop phospholipid-based injectable phase transition in situ gels (PTIGs) for the sus...
Preparation, characterization, and evaluation of the antitumor effect of kaempferol nanosuspensions
Preparation, characterization, and evaluation of the antitumor effect of kaempferol nanosuspensions
Kaempferol (KAE) is a naturally occurring flavonoid compound with antitumor activity. However, the low aqueous solubility,...
Development of doxorubicin-encapsulated magnetic liposome@PEG for treatment of breast cancer in BALB/c mice
Development of doxorubicin-encapsulated magnetic liposome@PEG for treatment of breast cancer in BALB/c mice
The magnetic doxorubicin-encapsulated liposome/PEG/Fe3O4 (called as DOX@m-Lip/PEG) was synthesized and studied as a novel ...
Drug formulation and delivery: a UK and Ireland perspective
Drug formulation and delivery: a UK and Ireland perspective
The United Kingdom and Ireland Controlled Release Society (UKICRS) is a local chapter of ...
Design of an imaging magnetic microsphere based on photopolymerization for magnetic hyperthermia in tumor therapy
Design of an imaging magnetic microsphere based on photopolymerization for magnetic hyperthermia in tumor therapy
Magnetic hyperthermia therapy has been widely used in the nonsurgical treatment of patients with advanced stage cancers th...
Functionalized zein nanoparticles targeting neonatal Fc receptor to enhance lung absorption of peptides
Functionalized zein nanoparticles targeting neonatal Fc receptor to enhance lung absorption of peptides
Peptides have a distinguished therapeutic potential for several chronic conditions, and more than 80 peptides exist in the...
Inulin-lipid hybrid (ILH) microparticles promote pH-triggered release of rifampicin within infected macrophages
Inulin-lipid hybrid (ILH) microparticles promote pH-triggered release of rifampicin within infected macrophages
Intracellular bacteria serve as a problematic source of infection due to their ability to evade biological immune response...
Efficacy and safety of needle-free jet injector-assisted intralesional treatments in dermatology—a systematic review
Efficacy and safety of needle-free jet injector-assisted intralesional treatments in dermatology—a systematic review
Needle-free jet injectors are used for the intralesional treatment of various dermatological indications. However, a syste...