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Multi-functional Chitosan Polymeric Micelles for improving the oral bioavailability of Paclitaxel based on synergistic effect
Multi-functional Chitosan Polymeric Micelles for improving the oral bioavailability of Paclitaxel based on synergistic effect
A novel multi-functional micelle delivery system was developed for enhancing the oral absorption of paclitaxel (PTX). The ...
Correction: Evaluation of mAb 2C5-modified dendrimer-based micelles for the co-delivery of siRNA and chemotherapeutic drug in xenograft mice model
Correction: Evaluation of mAb 2C5-modified dendrimer-based micelles for the co-delivery of siRNA and chemotherapeutic drug in xenograft mice model
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Microneedle patch with pure drug tips for delivery of liraglutide: pharmacokinetics in rats and minipigs
Microneedle patch with pure drug tips for delivery of liraglutide: pharmacokinetics in rats and minipigs
Transdermal delivery of peptide drugs is almost impossible with conventional penetration enhancers because of epidermal ba...
Effects of semaglutide-loaded lipid nanocapsules on metabolic dysfunction-associated steatotic liver disease
Effects of semaglutide-loaded lipid nanocapsules on metabolic dysfunction-associated steatotic liver disease
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a highly prevalent chronic liver disease that...
Anti-lung cancer synergy of low-dose doxorubicin and PD-L1 blocker co-delivered via mild photothermia-responsive black phosphorus
Anti-lung cancer synergy of low-dose doxorubicin and PD-L1 blocker co-delivered via mild photothermia-responsive black phosphorus
We have previously identified a latent interaction mechanism between non-small cell lung cancer cells (NSCLCC) and their a...
Manufacturing and characterisation of 3D-printed sustained-release Timolol implants for glaucoma treatment
Manufacturing and characterisation of 3D-printed sustained-release Timolol implants for glaucoma treatment
Timolol maleate (TML) is a beta-blocker drug that is commonly used to lower the intraocular pressure in glaucoma. This stu...
Influence of physico-chemical properties of two lipoxin emulsion-loaded hydrogels on pre-polarized macrophages: a comparative analysis
Influence of physico-chemical properties of two lipoxin emulsion-loaded hydrogels on pre-polarized macrophages: a comparative analysis
Inflammation, a crucial defense mechanism, must be rigorously regulated to prevent the onset of chronic inflammation and s...
A child-friendly anti-infective gummy formulation: Design, physicochemical, micromechanical, and taste sensory evaluation
A child-friendly anti-infective gummy formulation: Design, physicochemical, micromechanical, and taste sensory evaluation
The shortage of child friendly formulations constitutes a key part of the major challenges impeding the successful managem...
Correction: Partial inclusion complex assisted crosslinked β-cyclodextrin nanoparticles for improving therapeutic potential of docetaxel against breast cancer
Correction: Partial inclusion complex assisted crosslinked β-cyclodextrin nanoparticles for improving therapeutic potential of docetaxel against breast cancer
Cite this articleJain, S., Desai, M.R., Nallamothu, B. et al. Correction: Partial inclusion complex assisted crosslinked β...
A large-volume low-pressure nasal irrigation delivers drug into the nasal cavity? An in vivo study
A large-volume low-pressure nasal irrigation delivers drug into the nasal cavity? An in vivo study
The nasal administration route emerged as an interesting route in systemic and brain drug delivery, and different modaliti...
Folic/lactobionic acid dual-targeted polymeric nanocapsules for potential treatment of hepatocellular carcinoma
Folic/lactobionic acid dual-targeted polymeric nanocapsules for potential treatment of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a malignant tumor that affects many patients diagnosed with hepatic cell inflammation an...
Sulfo-butyl ether β-cyclodextrin inclusion complexes of bosutinib: in silico, in vitro and in vivo evaluation in attenuating the fast-fed variability
Sulfo-butyl ether β-cyclodextrin inclusion complexes of bosutinib: in silico, in vitro and in vivo evaluation in attenuating the fast-fed variability
Bosutinib (BOS) is a BCS class IV drug that shows low oral bioavailability and high fast-fed variability. Various pharmace...
Correction to: The effects of superparamagnetic iron oxide nanoparticles-labeled mesenchymal stem cells in the presence of a magnetic field on attenuation of injury after heart failure
Correction to: The effects of superparamagnetic iron oxide nanoparticles-labeled mesenchymal stem cells in the presence of a magnetic field on attenuation of injury after heart failure
Cite this articleNaseroleslami, M., Aboutaleb, N. & Parivar, K. Correction to: The effects of superparamagnetic iron o...
Quality by design approach-based fabrication and evaluation of self-nanoemulsifying drug delivery system for improved delivery of venetoclax
Quality by design approach-based fabrication and evaluation of self-nanoemulsifying drug delivery system for improved delivery of venetoclax
Breast cancer is reported as one of the most prevalent non-cutaneous malignancies in women. Venetoclax (VEN) is an approve...
Mucus-penetrating and permeation enhancer albumin-based nanoparticles for oral delivery of macromolecules: Application to bevacizumab
Mucus-penetrating and permeation enhancer albumin-based nanoparticles for oral delivery of macromolecules: Application to bevacizumab
The oral administration of therapeutic proteins copes with important challenges (mainly degradation and poor absorption) m...
Formulation and optimization of pH-sensitive nanocrystals for improved oral delivery
Formulation and optimization of pH-sensitive nanocrystals for improved oral delivery
The challenge of low water solubility in pharmaceutical science profoundly impacts drug absorption and therapeutic effecti...
A novel Posaconazole oral formulation using spray dried solid dispersion technology: in-vitro and in-vivo study
A novel Posaconazole oral formulation using spray dried solid dispersion technology: in-vitro and in-vivo study
SD (solid dispersion) technology is one of the well-recognized solubility enhancement methods; but the use of versatile ca...
Resveratrol nanocrystals based dissolving microneedles with highly efficient for rheumatoid arthritis
Resveratrol nanocrystals based dissolving microneedles with highly efficient for rheumatoid arthritis
Rheumatoid arthritis (RA) is a common immune disease characterized mainly by erosive arthritis with extensive clinical seq...
Polyelectrolyte complexes based on a novel and sustainable hemicellulose-rich lignosulphonate for drug delivery applications
Polyelectrolyte complexes based on a novel and sustainable hemicellulose-rich lignosulphonate for drug delivery applications
Polyelectrolyte complexes (PECs) are polymeric structures formed by the self-assembly of oppositely charged polymers. Nove...
Characterizing interregional differences in the rheological properties and composition of rat small intestinal mucus
Characterizing interregional differences in the rheological properties and composition of rat small intestinal mucus
The mucus layer in the small intestine is generally regarded as a barrier to drug absorption. However, the mucus layer is ...
The intracellular visualization of exogenous DNA in fluorescence microscopy
The intracellular visualization of exogenous DNA in fluorescence microscopy
In the development of non-viral gene delivery vectors, it is essential to reliably localize and quantify transfected DNA i...
Poly(malic acid)-budesonide nanoconjugates embedded in microparticles for lung administration
Poly(malic acid)-budesonide nanoconjugates embedded in microparticles for lung administration
To improve the therapeutic activity of inhaled glucocorticoids and reduce potential side effects, we designed a formulatio...
In vivo evaluation of a Nano-enabled therapeutic vitreous substitute for the precise delivery of triamcinolone to the posterior segment of the eye
In vivo evaluation of a Nano-enabled therapeutic vitreous substitute for the precise delivery of triamcinolone to the posterior segment of the eye
This study focused on the design of a thermoresponsive, nano-enabled vitreous substitute for the treatment of retinal dise...
RGD-coated polymeric microbubbles promote ultrasound-mediated drug delivery in an inflamed endothelium-pericyte co-culture model of the blood-brain barrier
RGD-coated polymeric microbubbles promote ultrasound-mediated drug delivery in an inflamed endothelium-pericyte co-culture model of the blood-brain barrier
Drug delivery to central nervous pathologies is compromised by the blood-brain barrier (BBB). A clinically explored strate...
Enhancing collagen based nanoemulgel for effective topical delivery of Aceclofenac and Citronellol oil: Formulation, optimization, in-vitro evaluation, and in-vivo osteoarthritis study with a focus on HMGB-1/RAGE/NF-κB pathway, Klotho, and miR-499a
Enhancing collagen based nanoemulgel for effective topical delivery of Aceclofenac and Citronellol oil: Formulation, optimization, in-vitro evaluation, and in-vivo osteoarthritis study with a focus on HMGB-1/RAGE/NF-κB pathway, Klotho, and miR-499a
The majority of conventional osteoarthritis (OA) treatments are based on molecular adjustment of certain signaling pathway...
Imiquimod nanocrystal-loaded dissolving microneedles prepared by DLP printing
Imiquimod nanocrystal-loaded dissolving microneedles prepared by DLP printing
The utilization of 3D printing– digital light processing (DLP) technique, for the direct fabrication of microneedles...
OX26-cojugated gangliosilated liposomes to improve the post-ischemic therapeutic effect of CDP-choline
OX26-cojugated gangliosilated liposomes to improve the post-ischemic therapeutic effect of CDP-choline
Cerebrovascular impairment represents one of the main causes of death worldwide with a mortality rate of 5.5 million per y...
Exogenous modification of EL-4 T cell extracellular vesicles with miR-155 induce macrophage into M1-type polarization
Exogenous modification of EL-4 T cell extracellular vesicles with miR-155 induce macrophage into M1-type polarization
Extracellular vesicles (EVs) show promising potential to be used as therapeutics, disease biomarkers, and drug delivery ve...
A liquid crystal in situ gel based on rotigotine for the treatment of Parkinson’s disease
A liquid crystal in situ gel based on rotigotine for the treatment of Parkinson’s disease
One of the most common neurodegenerative illnesses is Parkinson’s disease (PD). Rotigotine (RTG) is a dopamine agoni...
Folic acid grafted mixed polymeric micelles as a targeted delivery strategy for tamoxifen citrate in treatment of breast cancer
Folic acid grafted mixed polymeric micelles as a targeted delivery strategy for tamoxifen citrate in treatment of breast cancer
The objective of this study was to develop folic acid (FA) grafted mixed polymeric micelles loaded with Tamoxifen citrate ...
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