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Mechanical compression regulates tumor spheroid invasion into a 3D collagen matrix
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An effective hydrodynamic description of marching locusts
In the raw data (figure 2(Ci)) there is a clear anisotropy, with near neighbors more likely to be found on the sides than ...
Modeling cancer progression: an integrated workflow extending data-driven kinetic models to bio-mechanical PDE models
Computational modeling of cancer can help unveil dynamics and interactions that are hard to replicate experim...
Coupled action potential and calcium dynamics underlie robust spontaneous firing in dopaminergic neurons
Dopaminergic neurons (DAs) are specialized neurons tasked with dopamine secretion, which is crucial in regulation of muscl...
Structural maturation of myofilaments in engineered 3D cardiac microtissues characterized using small angle x-ray scattering
Understanding the structural and functional development of human-induced pluripotent stem-cell-derived cardio...
Universal calcium fluctuations in Hydra morphogenesis
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Seeking and sharing information in collective olfactory search
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Calcium storage in multivesicular endo-lysosome
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Rapid prediction of lab-grown tissue properties using deep learning
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High-throughput design of cultured tissue moulds using a biophysical model: optimising cell alignment
The technique presented here identifies tethered mould designs, optimised for growing cultured tissue with ve...
Calcium regulates cortex contraction in Physarum polycephalum
Parallel measurements of the fluorescent signal of the calcium-sensitive dye Calcium Green-1 and the unspecific dye Texas ...
A thermodynamical model of non-deterministic computation in cortical neural networks
The total entropy of system A and system B, prior to compression, is defined as: The net entropy of system A and system B,...
EMT induces characteristic changes of Rho GTPases and downstream effectors with a mitosis-specific twist
Epithelial mesenchymal transition (EMT) is a cellular transformation of epithelial cells that entails the loss of apical-b...
Quantitative modeling of EGF receptor ligand discrimination via internalization proofreading
The epidermal growth factor receptor (EGFR) is a central regulator of cell physiology that is stimulated by m...
Phase transitions in insect swarms
In contrast with laboratory insect swarms, wild insect swarms display significant coordinated behaviour. It h...
Out-of-equilibrium gene expression fluctuations in the presence of extrinsic noise
Cellular processes are subjected to stochastic fluctuations. These fluctuations (or noise) can lead to phenotypic differen...
Fundamental insights into the correlation between chromosome configuration and transcription
Eukaryotic chromosomes exhibit a hierarchical organization that spans a spectrum of length scales, ranging fr...
Emergent dynamics in an astrocyte-neuronal network coupled via nitric oxide
In the brain, both neurons and glial cells work in conjunction with each other during information processing....
Enhanced germination and electrotactic behaviour of Phytophthora palmivora zoospores in weak electric fields
Soil-dwelling organisms such as bacteria, fungi and plant roots use environmental cues of physical, chemical and biologica...
Cyclic-polymer grafted colloids in spherical confinement: insights for interphase chromosome organization
Cyclic or loop polymers are distinct from their linear counterparts due to their lack of free ends. As opposed to linear c...
Data-driven discovery of stochastic dynamical equations of collective motion
Coarse-grained descriptions of collective motion of flocking systems are often derived for the macroscopic or...
Mitochondrial networks through the lens of mathematics
Cells are highly complex structures that exhibit a wide range of geometrical features on scales ranging from symmetric pro...