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Serum exosomal miR-451a acts as a candidate marker for pancreatic cancer
Serum exosomal miR-451a acts as a candidate marker for pancreatic cancer
ObjectivesThe aim of this study was to explore the diagnostic efficiency of serum exosomal miR-451a as a novel biomarker f...
Diagnostic value of combined prealbumin-to-fibrinogen and albumin-to-fibrinogen ratios in Hp-negative gastric cancer
Diagnostic value of combined prealbumin-to-fibrinogen and albumin-to-fibrinogen ratios in Hp-negative gastric cancer
BackgroundThis study aimed to investigate the diagnostic value of prealbumin-to-fibrinogen ratio (PFR) and albumin-to-fibr...
Meta-analysis of the diagnostic performance of serum carbohydrate antigen 19-9 for the detection of gallbladder cancer
Meta-analysis of the diagnostic performance of serum carbohydrate antigen 19-9 for the detection of gallbladder cancer
IntroductionCarbohydrate antigen 19-9 (CA19-9) is a well-studied tumor marker, yet its diagnostic value for gallbladder ca...
Hypermethylation of the RASSF1A gene promoter as the tumor DNA marker for nasopharyngeal carcinoma
Hypermethylation of the RASSF1A gene promoter as the tumor DNA marker for nasopharyngeal carcinoma
BackgroundRASSF1A is a tumor suppressor gene. The methylation of RASSF1A has been reported to be associated with nasophary...
Clinicopathological significance of DAPK gene promoter hypermethylation in non-small cell lung cancer: A meta-analysis
Clinicopathological significance of DAPK gene promoter hypermethylation in non-small cell lung cancer: A meta-analysis
BackgroundDeath-associated protein kinase (DAPK) has a strong function of tumor suppression involving apoptosis regulation...
Exploring the association with disease recurrence of miRNAs predictive of colorectal cancer
Exploring the association with disease recurrence of miRNAs predictive of colorectal cancer
IntroductionDisease recurrence after surgery is a crucial predictor of poor prognosis in colorectal cancer, where dissemin...
System analysis of VEGFA in renal cell carcinoma: The expression, prognosis, gene regulation network and regulation targets
System analysis of VEGFA in renal cell carcinoma: The expression, prognosis, gene regulation network and regulation targets
BackgroundVEGFA is one of the most important regulators of angiogenesis and plays a crucial role in cancer angiogenesis an...
The association of hepatitis C virus infection and thyroid disease: A systematic review and meta-analysis
The association of hepatitis C virus infection and thyroid disease: A systematic review and meta-analysis
BackgroundPrevious studies have reported that hepatitis C virus infection may increase the risk of thyroid disease and eve...
BAX gene (−248 G > A) polymorphism in a sample of patients diagnosed with thyroid cancer in the Federal District, Brazil
BAX gene (−248 G > A) polymorphism in a sample of patients diagnosed with thyroid cancer in the Federal District, Brazil
IntroductionPapillary thyroid cancer corresponds to approximately 1% of all carcinomas; nevertheless, it is the most preva...
The isocitrate dehydrogenase 1 is a potential prognostic indicator for non-small cell lung cancer patients
The isocitrate dehydrogenase 1 is a potential prognostic indicator for non-small cell lung cancer patients
BackgroundThe serum isocitrate dehydrogenase 1(IDH1) level is significantly elevated in patients with non-small cell lung ...
Circ_0039411 promotes papillary thyroid carcinoma development through mediating the miR-423-5p/SOX4 signaling
Circ_0039411 promotes papillary thyroid carcinoma development through mediating the miR-423-5p/SOX4 signaling
BackgroundPapillary thyroid carcinoma is the most frequent histological subtype of thyroid cancer with a high incidence. W...
SOX2 as a prognostic marker and a potential molecular target in cervical cancer: A meta-analysis
SOX2 as a prognostic marker and a potential molecular target in cervical cancer: A meta-analysis
BackgroundSex determining region Y-box 2 (SOX2) has been reported as a potential therapeutic target for cancer. However, t...
The diagnostic value of the combination of carcinoembryonic antigen, squamous cell carcinoma-related antigen, CYFRA 21-1, neuron-specific enolase, tissue polypeptide antigen, and progastrin-releasing peptide in small cell lung cancer discrimination
The diagnostic value of the combination of carcinoembryonic antigen, squamous cell carcinoma-related antigen, CYFRA 21-1, neuron-specific enolase, tissue polypeptide antigen, and progastrin-releasing peptide in small cell lung cancer discrimination
BackgroundThe diagnostic value of six tumor markers was investigated and the appropriate combinations of those tumor marke...
TMPRSS4 overexpression promotes the metastasis of colorectal cancer and predicts poor prognosis of stage III–IV colorectal cancer
TMPRSS4 overexpression promotes the metastasis of colorectal cancer and predicts poor prognosis of stage III–IV colorectal cancer
PurposeTo study in detail the expression pattern and prognostic significance of TMPRSS4 in colorectal cancer.MethodsThe ex...
The relevance analysis of GSTP1 rs1695 and lung cancer in the Chinese Han population
The relevance analysis of GSTP1 rs1695 and lung cancer in the Chinese Han population
BackgroundThis study explored the relevance between rs1695 and susceptibility to the lung cancer in the Chinese Han popula...
Serum epithelial membrane protein 1 serves as a feasible biomarker in extrahepatic cholangiocarcinoma
Serum epithelial membrane protein 1 serves as a feasible biomarker in extrahepatic cholangiocarcinoma
BackgroundExtrahepatic cholangiocarcinoma is a malignancy that originates from bile duct epithelium with an unfavorable pr...
Circ_0006174 promotes colorectal cancer progression by sponging microRNA-142-3p and regulating X-linked inhibitor of apoptosis expression
Circ_0006174 promotes colorectal cancer progression by sponging microRNA-142-3p and regulating X-linked inhibitor of apoptosis expression
BackgroundCircular RNAs (circRNAs) are crucial in the regulation of gene expression and biological processes. However, in ...
The prognostic significance of microRNA-221 in hepatocellular carcinoma: An updated meta-analysis
The prognostic significance of microRNA-221 in hepatocellular carcinoma: An updated meta-analysis
BackgroundRecently, microRNA-221 has been found to be abnormally expressed in hepatocellular carcinoma; however, its clini...
The prognostic value of serum bilirubin in colorectal cancer patients with surgical resection
The prognostic value of serum bilirubin in colorectal cancer patients with surgical resection
PurposeSerum bilirubin plays an important role in antioxidant and anticancer processes. The inverse association between se...
Five MDM4 gene polymorphisms on cancer risk: An updated systematic review and meta-analysis
Five MDM4 gene polymorphisms on cancer risk: An updated systematic review and meta-analysis
PurposeThe study aims to provide a comprehensive account of the association of five MDM4 gene polymorphisms (rs1380576, rs...
Impact of EPclin on adjuvant therapeutic decision making and comparison of EPclin to the PREDICT tool
Impact of EPclin on adjuvant therapeutic decision making and comparison of EPclin to the PREDICT tool
Purpose:Genomic signatures, such as EndoPredict®, may help clinicians to decide which adjuvant treatment is the most appro...
The role of single nucleotide polymorphisms of miRNAs 100 and 146a as prognostic factors for prostate cancer
The role of single nucleotide polymorphisms of miRNAs 100 and 146a as prognostic factors for prostate cancer
Introduction:Prostate cancer has a high incidence in men and is the second cause of cancer death among americans male. mic...
Clinical characteristics and prognostic value of the KRAS mutation in Chinese colorectal cancer patients
Clinical characteristics and prognostic value of the KRAS mutation in Chinese colorectal cancer patients
Background:The KRAS mutations are high-frequency somatic mutations found in colorectal cancer patients from Western and As...
A novel decision tree model based on chromosome imbalances in cell-free DNA and CA-125 in the differential diagnosis of ovarian cancer
A novel decision tree model based on chromosome imbalances in cell-free DNA and CA-125 in the differential diagnosis of ovarian cancer
Objective:CA-125 is widely used as biomarker of ovarian cancer. However, CA-125 suffers low accuracy. We developed a hybri...
Correlation Between the Glasgow Prognostic Score and the Serum Cytokine Profile in Taiwanese Patients with Colorectal Cancer
Correlation Between the Glasgow Prognostic Score and the Serum Cytokine Profile in Taiwanese Patients with Colorectal Cancer
Background:The Glasgow Prognostic Score and circulating cytokine levels are related to the prognosis of colorectal cancer ...
Clinical value of serum and exhaled breath condensate inflammatory factor IL-11 levels in non-small cell lung cancer: Clinical value of IL-11 in non-small cell lung cancer
Clinical value of serum and exhaled breath condensate inflammatory factor IL-11 levels in non-small cell lung cancer: Clinical value of IL-11 in non-small cell lung cancer
Objective:Our study aimed to observe and evaluate the clinical value of interleukin (IL)-11 in the serum and exhaled breat...
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