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PEGylated and functionalized polylactide-based nanocapsules: An overview
Polymeric nanocapsules (NC) are versatile mixed vesicular nanocarriers, generally containing a lipid core with a polymeric...
CDX-modified chitosan nanoparticles remarkably reduce therapeutic dose of fingolimod in the EAE model of mice
Fingolimod (Fin), an FDA-approved drug, is used to control relapsing-remitting multiple sclerosis (MS). This therapeutic a...
Co-delivery of gemcitabine and Triapine by calcium carbonate nanoparticles against chemoresistant pancreatic cancer
Pancreatic cancer is a malignant disease with high mortality, and its systemic treatment strategy mainly focuses on chemot...
Novel bilayer coating on gentamicin-loaded titanium nanotube for orthopedic implants applications
Fabricating a multifunctional orthopedic implant which prevents post-surgery infection is highly desirable in advanced mat...
Tumor targeted combination therapeutic system for the effective treatment of drug resistant triple negative breast cancer
Breast cancer has become the malignant tumor with the largest incidence, especially the drug resistant triple negative bre...
Improved infectious burn wound healing by applying lyophilized particles containing probiotics and prebiotics
Lactiplantibacillus plantarum cells were encapsulated in a mixture of cationic and anionic polymers, with the final compos...
Preoperative administration of a biomimetic platelet nanodrug enhances postoperative drug delivery by bypassing thrombus
The postoperative thrombus attached to the damaged blood vessels severely obstructs drugs from crossing the damaged blood–...
Formulation optimization of sterilized xanthones-loaded nanoemulgels and evaluation of their wound healing activities
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Delivering mRNA to a human NK cell line, NK-92 cells, by lipid nanoparticles
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Unconventional and conventional Pickering emulsions: Perspectives and challenges in skin applications
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Machine learning in additive manufacturing & Microfluidics for smarter and safer drug delivery systems
3PNN3D Printing and Neural Network co-modellingAIArtificial IntelligenceANNsArtificial Neural NetworksAPIsActive Pharmaceu...
Nanofiber-coated implants: Development and safety after intravitreal application in rabbits
Intravitreal injections are the preferred choice for drug administration to the posterior segment of the eye. However, the...
Control of API release with matrix polymorphism in tristearin microspheres
Glycerides are widely employed as solid matrices in a range of pharmaceutical intermediates and dosage forms. Diffusion-ba...
Preclinical modeling of intravitreal suspensions
There are a number of obstacles that complicate the development of intravitreal delivered small molecules therapies. One s...
In situ rearranged multifunctional lipid nanoparticles via synergistic potentiation for oral insulin delivery
Oral administration of therapeutic peptides/proteins (TPPs) is confronted with multiple gastrointestinal (GI) barriers suc...
Cuprous oxide nanoparticles incorporated into a polymeric matrix embedded in fabrics to prevent spread of SARS-CoV-2
This paper describes the development of a coating for cotton and polypropylene (PP) fabrics based on a polymeric matrix em...
Anionic polysaccharides for stabilization and sustained release of antimicrobial peptides
Chemical and enzymatic in vivo degradation of antimicrobial peptides represents a major challenge for their therapeutic us...
Monitoring dexamethasone skin biodistribution with ex vivo MALDI-TOF mass spectrometry imaging and confocal Raman microscopy
Two of the most promising techniques in terms of ex vivo skin imaging and quantifying are confocal Raman microscopy and MA...