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Luteolin-incorporated fish collagen hydrogel scaffold: An effective drug delivery strategy for wound healing
Luteolin-incorporated fish collagen hydrogel scaffold: An effective drug delivery strategy for wound healing
The human body's astounding capacity to repair wounds is a complicated and necessary mechanism that is required to maintai...
Topical pickering emulsion versus classical excipients: A study of the residual film on the human skin
Topical pickering emulsion versus classical excipients: A study of the residual film on the human skin
The interest in Pickering emulsions is based on the possibility of replacing classical emulsifiers with solid particles. T...
Development and Application of Control Concepts for Twin-Screw Wet Granulation in the ConsiGmaTM-25: Part 1 Granule Composition
Development and Application of Control Concepts for Twin-Screw Wet Granulation in the ConsiGmaTM-25: Part 1 Granule Composition
Continuous manufacturing of pharmaceutical products has the potential to enhance product quality, reduce environmental foo...
Development and Application of Control Concepts for Twin-Screw Wet Granulation in the ConsiGmaTM-25: Part 2 Granule Size
Development and Application of Control Concepts for Twin-Screw Wet Granulation in the ConsiGmaTM-25: Part 2 Granule Size
A conventional approach to ensuring the safety and quality of pharmaceutical products is the so-called Quality-by-Testing ...
Paediatric clinical study of 3D printed personalised medicines for rare metabolic disorders
Paediatric clinical study of 3D printed personalised medicines for rare metabolic disorders
KeywordsSemi-solid extrusion 3D printingPediatricsDirect ink writingPolypillsPatient acceptability of formulationsAdditive...
Antimicrobial liposomes-in-nanofiber wound dressings prepared by a green and sustainable wire-electrospinning set-up
Antimicrobial liposomes-in-nanofiber wound dressings prepared by a green and sustainable wire-electrospinning set-up
Increasing prevalence of infected and chronic wounds demands improved therapy options. In this work an electrospun nanofib...
A pH/ROS-responsive antioxidative and antimicrobial GelMA hydrogel for on-demand drug delivery and enhanced osteogenic differentiation in vitro
A pH/ROS-responsive antioxidative and antimicrobial GelMA hydrogel for on-demand drug delivery and enhanced osteogenic differentiation in vitro
Bone tissue repair and regeneration remain significant clinical challenges, especially in cases of infected bone defects (...
Pegylated-liposomes increase the efficacy of Idelalisib in lymphoma B-cells
Pegylated-liposomes increase the efficacy of Idelalisib in lymphoma B-cells
New drugs and technologies are continuously developed to improve the efficacy and minimize the critical side effects of ca...
Impact of formulation parameters on self-assembled liposomes (LeciPlex® III): A detailed investigation
Impact of formulation parameters on self-assembled liposomes (LeciPlex® III): A detailed investigation
Explorations in liposome manufacturing techniques have facilitated the development of drug delivery systems for various cy...
Acetazolamide encapsulation in elastin like recombinamers using a supercritical antisolvent (SAS) process for glaucoma treatment
Acetazolamide encapsulation in elastin like recombinamers using a supercritical antisolvent (SAS) process for glaucoma treatment
Glaucoma, which is asymptomatic until a relatively late stage, is recognized as a worldwide cause of irreversible loss of ...
Investigating the effectiveness of liposome-bacteriophage nanocomplex in killing Staphylococcus aureus using epithelial cell coculture models
Investigating the effectiveness of liposome-bacteriophage nanocomplex in killing Staphylococcus aureus using epithelial cell coculture models
Respiratory tract infections induced by antimicrobial-resistant (AMR) bacterial pathogens due to global antibiotic abuse h...
Evaluation of layer-by-layer assembly systems for drug delivery and antimicrobial properties in orthopaedic application
Evaluation of layer-by-layer assembly systems for drug delivery and antimicrobial properties in orthopaedic application
Ti6Al4V (Ti64) implants are widely used to treat one disease. However, bacterial colonization and interaction with cells p...
Formulation and In Vitro-Ex vivo Evaluation of Cannabidiol and Cannabidiol-Valine-Hemisuccinate Loaded Lipid-Based Nanoformulations for Ocular Applications
Formulation and In Vitro-Ex vivo Evaluation of Cannabidiol and Cannabidiol-Valine-Hemisuccinate Loaded Lipid-Based Nanoformulations for Ocular Applications
Cannabis sativa L. is a herbaceous plant containing psychoactive agents popular for its recreational and medicinal uses (K...
A novel approach to pH-Responsive targeted cancer Therapy: Inhibition of FaDu cancer cell proliferation with a pH low insertion Peptide-Conjugated DGAT1 inhibitor
A novel approach to pH-Responsive targeted cancer Therapy: Inhibition of FaDu cancer cell proliferation with a pH low insertion Peptide-Conjugated DGAT1 inhibitor
Acidosis, like hypoxia, is a prevalent characteristic of solid tumor microenvironment (Corbet and Feron, 2017b, Pillai et ...
Ruxolitinib-loaded cytokine nanosponge alleviated the cytokine storm and dampened macrophage overactivation for the treatment of hemophagocytic lymphohistiocytosis
Ruxolitinib-loaded cytokine nanosponge alleviated the cytokine storm and dampened macrophage overactivation for the treatment of hemophagocytic lymphohistiocytosis
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening clinical syndrome with poor prognoses. Clinical manifestati...
In-situ forming PLGA implants: Towards less toxic solvents
In-situ forming PLGA implants: Towards less toxic solvents
In-situ forming poly(lactic-co-glycolic acid) (PLGA) implants offer a great potential for controlled drug delivery for a v...
Novel drug-drug salt crystals of metformin with ibuprofen or naproxen: Improved solubility, dissolution rate, and synergistic antinociceptive effects
Novel drug-drug salt crystals of metformin with ibuprofen or naproxen: Improved solubility, dissolution rate, and synergistic antinociceptive effects
Pain remains as a major clinical problem which affects about 20 % of the adult population worldwide (Zhuang et al., 2021)....
Plasmonic laser-responsive BioDissolve 3D-printed graphene@cisplatin-implant for prevention of post-surgical relapse of oral cancer
Plasmonic laser-responsive BioDissolve 3D-printed graphene@cisplatin-implant for prevention of post-surgical relapse of oral cancer
Oral cancer is a type of head and neck cancer that can develop in any part of the mouth, including the lips, tongue, gums,...
Design of smart chemotherapy of doxorubicin hydrochloride using nanostructured lipid carriers and solid lipid nanoparticles for improved anticancer efficacy
Design of smart chemotherapy of doxorubicin hydrochloride using nanostructured lipid carriers and solid lipid nanoparticles for improved anticancer efficacy
Doxorubicin hydrochloride (DOX), an anthracycline antibiotic, is approved for cancer chemotherapy (O'Shaughnessy, 2003, Ro...
Nanomicelles empower natamycin in treating fungal keratitis: An in vitro, ex vivo and in vivo study
Nanomicelles empower natamycin in treating fungal keratitis: An in vitro, ex vivo and in vivo study
Fungal keratitis is one of the major causes of corneal blindness affecting 6 to 8 million people globally (WHO, 2019a, WHO...
The drug loading capacity prediction and cytotoxicity analysis of metal–organic frameworks using stacking algorithms of machine learning
The drug loading capacity prediction and cytotoxicity analysis of metal–organic frameworks using stacking algorithms of machine learning
Metal–organic frameworks (MOFs, also known as porous coordination polymers) are an emerging class of porous materials cons...
Nanoscale colocalized thermal and chemical mapping of pharmaceutical powder aerosols
Nanoscale colocalized thermal and chemical mapping of pharmaceutical powder aerosols
Dry powder inhaler (DPI) therapy has been shown to be effective in treating chronic obstructive pulmonary disease (COPD), ...
AI-driven design of customized 3D-printed multi-layer capsules with controlled drug release profiles for personalized medicine
AI-driven design of customized 3D-printed multi-layer capsules with controlled drug release profiles for personalized medicine
Three-dimensional (3D) printing emerged as an advanced technology for rapid prototyping, enabling the production of intric...
Combinational strategy using albumin-based nanoparticles to enable synergetic anti-rheumatic efficacy and reduced hepatotoxicity
Combinational strategy using albumin-based nanoparticles to enable synergetic anti-rheumatic efficacy and reduced hepatotoxicity
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that primarily cause widespread inflammatory responses ...
Enabling superior drug loading in lipid-based formulations with lipophilic salts for a brick dust molecule: Exploration of lipophilic counterions and in vitro-in vivo evaluation
Enabling superior drug loading in lipid-based formulations with lipophilic salts for a brick dust molecule: Exploration of lipophilic counterions and in vitro-in vivo evaluation
In recent decades, a growing concern has emerged with approximately 60 % of newly discovered compounds exhibiting poor sol...
Critical parameters to standardize the size and concentration determination of nanomaterials by nanoparticle tracking analysis
Critical parameters to standardize the size and concentration determination of nanomaterials by nanoparticle tracking analysis
Nanomaterials including extracellular vesicles and synthetic nanoparticles are of broad diagnostic and therapeutic applica...
Inhalable FN-binding liposomes or liposome-exosome hybrid bionic vesicles encapsulated microparticles for enhanced pulmonary fibrosis therapy
Inhalable FN-binding liposomes or liposome-exosome hybrid bionic vesicles encapsulated microparticles for enhanced pulmonary fibrosis therapy
Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible interstitial lung disease with high mortality and po...
Mucoadhesive polymers: Design of S-protected thiolated cyclodextrin-based hydrogels
Mucoadhesive polymers: Design of S-protected thiolated cyclodextrin-based hydrogels
AimThis study aims to design chemically crosslinked thiolated cyclodextrin-based hydrogels and to evaluate their mucoadhes...
Flexible modelling of the dissolution performance of directly compressed tablets
Flexible modelling of the dissolution performance of directly compressed tablets
Volume 656, 10 May 2024, 124084Author links open overlay panel, , , , , , , AbstractIn this study, a compartmental disinte...
Pegylated liposome encapsulating docetaxel using microfluidic mixing technique: Process optimization and results in breast cancer models
Pegylated liposome encapsulating docetaxel using microfluidic mixing technique: Process optimization and results in breast cancer models
KeywordsLiposomesBiopharmaceutical developmentMicrofluidic mixing techniqueBreast cancerDocetaxelPharmacokineticsAbbreviat...
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