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Choroid plexus and perivascular space enlargement in neuropsychiatric systemic lupus erythematosus
Choroid plexus and perivascular space enlargement in neuropsychiatric systemic lupus erythematosus
Choroid plexus (CP) enlargement is proposed as a marker of neuroinflammation in immune-mediated conditions. CP involvement...
The neural signature of psychomotor disturbance in depression
The neural signature of psychomotor disturbance in depression
Up to 70% of patients with major depressive disorder present with psychomotor disturbance (PmD), but at the present time u...
Germline PTEN genotype-dependent phenotypic divergence during the early neural developmental process of forebrain organoids
Germline PTEN genotype-dependent phenotypic divergence during the early neural developmental process of forebrain organoids
PTEN germline mutations account for ~0.2–1% of all autism spectrum disorder (ASD) cases, as well as ~17% of ASD pati...
Molecular consequences of PQBP1 deficiency, involved in the X-linked Renpenning syndrome
Molecular consequences of PQBP1 deficiency, involved in the X-linked Renpenning syndrome
Mutations in the PQBP1 gene (polyglutamine-binding protein-1) are responsible for a syndromic X-linked form of neurodevelo...
The role of polyunsaturated fatty acids in the neurobiology of major depressive disorder and suicide risk
The role of polyunsaturated fatty acids in the neurobiology of major depressive disorder and suicide risk
Long-chain polyunsaturated fatty acids (LC-PUFAs) are obtained from diet or derived from essential shorter-chain fatty aci...
Microglia shape AgRP neuron postnatal development via regulating perineuronal net plasticity
Microglia shape AgRP neuron postnatal development via regulating perineuronal net plasticity
The hypothalamus plays a crucial role in controlling metabolism and energy balance, with Agouti-related protein (AgRP) neu...
Clarity on the blazing trail: clearing the way for amyloid-removing therapies for Alzheimer’s disease
Clarity on the blazing trail: clearing the way for amyloid-removing therapies for Alzheimer’s disease
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with a complex pathogenesis. Senile plaques com...
Intrinsic plasticity of Purkinje cell serves homeostatic regulation of fear memory
Intrinsic plasticity of Purkinje cell serves homeostatic regulation of fear memory
Two forms of plasticity, synaptic and intrinsic, are neural substrates for learning and memory. Abnormalities in homeostat...
Correction: Targeting NLRP3 inflammasome for neurodegenerative disorders
Correction to: Molecular Psychiatry, published online 5 September 2023In this article, an incorrect table...
Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression
Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression
Neurostimulation is a mainstream treatment option for major depression. Neuromodulation techniques apply repetitive magnet...
Impaired neural stress resistance and loss of REST in bipolar disorder
Impaired neural stress resistance and loss of REST in bipolar disorder
Neurodevelopmental changes and impaired stress resistance have been implicated in the pathogenesis of bipolar disorder (BD...
Functional involvement of septal miR-132 in extinction and oxytocin-mediated reversal of social fear
Functional involvement of septal miR-132 in extinction and oxytocin-mediated reversal of social fear
Social interactions are critical for mammalian survival and evolution. Dysregulation of social behavior often leads to psy...
Integrative transcriptome- and DNA methylation analysis of brain tissue from the temporal pole in suicide decedents and their controls
Integrative transcriptome- and DNA methylation analysis of brain tissue from the temporal pole in suicide decedents and their controls
Suicide rates have increased steadily world-wide over the past two decades, constituting a serious public health crisis th...
Synergistic psychedelic - NMDAR modulator treatment for neuropsychiatric disorders
Synergistic psychedelic - NMDAR modulator treatment for neuropsychiatric disorders
Modern research data suggest a therapeutic role for serotonergic psychedelics in depression and other neuropsychiatric dis...
The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment
The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment
The stimulant methylphenidate (MPH) and the non-stimulant atomoxetine (ATX) are frequently used for the treatment of atten...
An umbrella review of candidate predictors of response, remission, recovery, and relapse across mental disorders
An umbrella review of candidate predictors of response, remission, recovery, and relapse across mental disorders
We aimed to identify diagnosis-specific/transdiagnostic/transoutcome multivariable candidate predictors (MCPs) of key outc...
Clinical characteristics indexing genetic differences in bipolar disorder – a systematic review
Clinical characteristics indexing genetic differences in bipolar disorder – a systematic review
Bipolar disorder is a heterogenous condition with a varied clinical presentation. While progress has been made in identify...
Modelling the overlap and divergence of autistic and schizotypal traits on hippocampal subfield volumes and regional cerebral blood flow
Modelling the overlap and divergence of autistic and schizotypal traits on hippocampal subfield volumes and regional cerebral blood flow
Psychiatric disorders show high co-morbidity, including co-morbid expressions of subclinical psychopathology across multip...
Pathogenic mechanisms of human immunodeficiency virus (HIV)-associated pain
Chronic pain is a prevalent neurological complication among individuals living with human immunodeficiency virus (PLHIV) i...
Impaired functional connectivity of the hippocampus in translational murine models of NMDA-receptor antibody associated neuropsychiatric pathology
Impaired functional connectivity of the hippocampus in translational murine models of NMDA-receptor antibody associated neuropsychiatric pathology
Decreased hippocampal connectivity and disruption of functional networks are established resting-state functional MRI (rs-...
Decreased mononuclear cell NR3C1 SKA2 and FKPB5 expression levels among adult survivors of suicide bombing terror attacks in childhood are associated with the development of PTSD
Decreased mononuclear cell NR3C1 SKA2 and FKPB5 expression levels among adult survivors of suicide bombing terror attacks in childhood are associated with the development of PTSD
Life threatening trauma and the development of PTSD during childhood, may each associate with transcriptional perturbation...
Functional connectivity of amygdala subnuclei in PTSD: a narrative review
Functional connectivity of amygdala subnuclei in PTSD: a narrative review
While the amygdala is often implicated in the neurobiology of posttraumatic stress disorder (PTSD), the pattern of results...
Maternal oxidative stress during pregnancy associated with emotional and behavioural problems in early childhood: implications for foetal programming
Maternal oxidative stress during pregnancy associated with emotional and behavioural problems in early childhood: implications for foetal programming
Childhood mental disorders, including emotional and behavioural problems (EBP) are increasingly prevalent. Higher maternal...
Emerging role of the host microbiome in neuropsychiatric disorders: overview and future directions
Emerging role of the host microbiome in neuropsychiatric disorders: overview and future directions
The human body harbors a diverse ecosystem of microorganisms, including bacteria, viruses, and fungi, collectively known a...
Altered pupil responses to social and non-social stimuli in Shank3 mutant dogs
Altered pupil responses to social and non-social stimuli in Shank3 mutant dogs
Pupillary response, an important process in visual perception and social and emotional cognition, has been widely studied ...
Myelin-associated oligodendrocytic basic protein-dependent myelin repair confers the long-lasting antidepressant effect of ketamine
Myelin-associated oligodendrocytic basic protein-dependent myelin repair confers the long-lasting antidepressant effect of ketamine
Ketamine exhibits rapid and sustained antidepressant effects. As decreased myelination has been linked to depression patho...
Modeling SHANK3-associated autism spectrum disorder in Beagle dogs via CRISPR/Cas9 gene editing
Modeling SHANK3-associated autism spectrum disorder in Beagle dogs via CRISPR/Cas9 gene editing
Despite intensive studies in modeling neuropsychiatric disorders especially autism spectrum disorder (ASD) in animals, man...
Genomic findings in schizophrenia and their implications
Genomic findings in schizophrenia and their implications
There has been substantial progress in understanding the genetics of schizophrenia over the past 15 years. This has reveal...
Effects of escitalopram on synaptic density in the healthy human brain: a randomized controlled trial
Effects of escitalopram on synaptic density in the healthy human brain: a randomized controlled trial
Selective serotonin reuptake inhibitors (SSRIs) are widely used for treating neuropsychiatric disorders. However, the exac...
Pharmacological interventions for antipsychotic-related sialorrhea: a systematic review and network meta-analysis of randomized trials
Pharmacological interventions for antipsychotic-related sialorrhea: a systematic review and network meta-analysis of randomized trials
Antipsychotic-induced sialorrhea carries a significant burden, but evidence-based treatment guidance is incomplete, warran...
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