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Chemically cross-linked hydrogels from repetitive protein arrays
Biomaterials for tissue regeneration must mimic the biophysical properties of the native physiological environment. A prot...
A practical multicellular sample preparation pipeline broadens the application of in situ cryo-electron tomography
Compared to the divide-and-conquer approach employed in single particle analysis by cryogenic electron microscopy, cryo-el...
A practical multicellular sample preparation pipeline broadens the application of in situ cryo-electron tomography
Compared to the divide-and-conquer approach employed in single particle analysis by cryogenic electron microscopy, cryo-el...
NMR sample optimization and backbone assignment of a stabilized neurotensin receptor
G protein-coupled receptors (GPCRs) are one of the largest groups of membrane proteins encoded by the human genome. These ...
Cage versus Sheet: Probing the Determinants of Protein – Cucurbit[7]uril Crystalline Architectures
The donut-shaped cucurbit[n]urils (Qn) are a class of rigid macrocyclic receptor with protein recognition capabilities. Qn...
The Anatomical and Micromorphological Properties of Endemic Species to Gypsic Soils of Semnan, Iran
The Flora of Iran is so diverse and it is one of the richest plant diversity countries in Southwest Asia. The great differ...
OpenFIBSEM: A universal API for FIBSEM control
This paper introduces OpenFIBSEM, a universal API to control Focused Ion Beam Scanning Electron Microscopes (FIBSEM). Open...
Non-equilibrium Virus Particle Dynamics: Microsecond MD Simulations of the Complete Flock House Virus Capsid Under Different Conditions
Flock House virus (FHV) is an animal virus and considered a model system for non-enveloped viruses. It has a small, icosah...
Measuring cryo-TEM sample thickness using reflected light microscopy and machine learning
In cryo-transmission electron microscopy (cryo-TEM), sample thickness is one of the most important parameters that governs...
Structural insight to elucidate the binding specificity of the anti-cortisol Fab fragment with glucocorticoids
Cortisol is a steroid hormone that is produced by the adrenal gland. It is a primary stress hormone that increases glucose...
SUMOylation and the oncogenic E17K mutation affect AKT1 subcellular distribution and impact on Nanog-binding dynamics to chromatin in embryonic stem cells
AKT/PKB is a ubiquitous serine-threonine kinase known to mediate the action of a wide range of stimuli thus regulating a p...
Recent advances in the application of atomic force microscopy to structural biology
Biological molecules, such as carbohydrates, lipids, nucleic acids, and proteins are involved in crucial tasks of cellular...
Protein repeats evolve and emerge in giant viruses
Nucleocytoplasmatic large DNA viruses (NCLDVs or giant viruses) stand out because of their relatively large genomes encodi...
A review of the approaches used to solve sub-100 kDa membrane proteins by cryo-electron microscopy
Membrane proteins (MPs) are essential components of all biological membranes, contributing to key cellular functions that ...
Single particle cryo-EM analysis of Rickettsia conorii Sca2 reveals a formin-like core
Spotted fever group Rickettsia undergo actin-based motility inside infected eukaryotic cells using Sca2 (surface cell anti...
Cryo-EM reveals the structure and dynamics of a 723-residue malate synthase G
Determination of sub-100 kilodalton (kDa) structures by cryo-electron microscopy (EM) is a longstanding but not straightfo...
The crystal structure of Mycobacterium thermoresistibile MurE ligase reveals the binding mode of the substrate m-diaminopimelate
The cytoplasmatic biosynthesis of the stem peptide from the peptidoglycan in bacteria involves six steps, which have the r...
Direct control of shell regeneration by the mantle tissue in the pearl oyster Pinctada fucata
Molluscs rapidly repair the damaged shells to prevent further injury, which is vital for their survival after physical or ...
CryoEM single particle reconstruction with a complex-valued particle stack
Single particle reconstruction (SPR) in cryoEM is an image processing task with an elaborate hierarchy that starts with ma...
High-throughput segmentation, data visualization, and analysis of sea star skeletal networks
The remarkably complex skeletal systems of the sea stars (Echinodermata, Asteroidea), consisting of hundreds to thousands ...
Spectroscopic studies for identifying the chemical states of the periostracum of the Corbicula species in Lake Biwa
Corbicula clam shells consist of thin periostracum and calcareous layers made of calcium carbonate (CaCO3). Depending on h...
Four-dimensional microED of conformational dynamics in protein microcrystals on the femto-to-microsecond timescales
As structural determination of protein complexes approaches atomic resolution, there is an increasing focus on conformatio...
A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region
Small GTPase RhoA switches from GTP-bound state to GDP-bound state by hydrolyzing GTP, which is accelerated by GTPases act...
Insights into the oligomeric structure of the HIV-1 Vpu protein
The HIV-1-encoded protein Vpu forms an oligomeric ion channel/pore in membranes and interacts with host proteins to suppor...
Cryo-EM image alignment: from pair-wise to joint with deep unsupervised difference learning
Cryo-electron microscopy (cryo-EM) single-particle analysis is a revolutionary imaging technique to resolve and visualize ...
Revisiting the Ramachandran plot based on statistical analysis of static and dynamic characteristics of protein structures
Ramachandran plots, which describe protein structures by plotting the dihedral angle pairs of the backbone on a two-dimens...
Potential Implications of the Glycosylation Patterns in Collagen α1(I) and α2(I) Chains for Fibril Assembly and Growth
O-Glycosylation of hydroxylysine (Hyl) in collagen occurs at an early stage of biosynthesis before the triple-helix has fo...
Patterns of crystal organization and calcite twin formation in planktonic, rotaliid, foraminifera shells and spines
keywordsCalcite twinsCrystal organization in foraminiferal shellsElectron backscatter diffrection (EBSD)Planktonic and ben...
Multishot tomography for high-resolution in situ subtomogram averaging
Cryo-electron tomography (cryo-ET) and subtomogram averaging (STA) can resolve protein complexes at near atomic resolution...
Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn2+-releasing mechanism
Peer review under responsibility of For special issues, the foot notes must be placed.For the SI “VSI:Coiled coils', Pleas...
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