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Crosstalk of nervous and immune systems in pancreatic cancer
Crosstalk of nervous and immune systems in pancreatic cancer
Pancreatic cancer is a highly malignant tumor known for its extremely low survival rate. The combination of genetic disord...
CTCF deletion alters the pluripotency and DNA methylation profile of human iPSCs
CTCF deletion alters the pluripotency and DNA methylation profile of human iPSCs
Pluripotent stem cells are characterized by their differentiation potential toward endoderm, mesoderm, and ectoderm. Howev...
Genome-wide DNA methylation changes upon DOT1L inhibition in hormone-responsive breast cancer cells
Genome-wide DNA methylation changes upon DOT1L inhibition in hormone-responsive breast cancer cells
Breast cancer (BC) is a heterogeneous disease characterized by several molecular subtypes that differ in clinical behavior...
Analyzing the cellular plasma membrane by fast and efficient correlative STED and platinum replica EM
Analyzing the cellular plasma membrane by fast and efficient correlative STED and platinum replica EM
The plasma membrane of mammalian cells links transmembrane receptors, various structural components, and membrane-binding ...
Varicocele and testicular cord torsion: immune testicular microenvironment imbalance
Varicocele and testicular cord torsion: immune testicular microenvironment imbalance
The main functions of the testis, steroidogenesis and spermatogenesis, depend on the endocrine axis and systemic and local...
Methoxychlor induces oxidative stress and impairs early embryonic development in pigs
Methoxychlor induces oxidative stress and impairs early embryonic development in pigs
Introduction: Methoxychlor (MXC) is an organochlorine pesticide (OCP) that was formerly used worldwide as an insecticide a...
Homemade: building the structure of the neurogenic niche
Homemade: building the structure of the neurogenic niche
Neural stem/progenitor cells live in an intricate cellular environment, the neurogenic niche, which supports their functio...
Recent insight into the role of macrophage in alcohol-associated liver disease: a mini-review
Recent insight into the role of macrophage in alcohol-associated liver disease: a mini-review
Alcohol-associated liver disease (ALD) is a condition that develops due to prolonged and excessive alcohol consumption. It...
Evolutionary degeneration of septins into pseudoGTPases: impacts on a hetero-oligomeric assembly interface
Evolutionary degeneration of septins into pseudoGTPases: impacts on a hetero-oligomeric assembly interface
The septin family of eukaryotic proteins comprises distinct classes of sequence-related monomers that associate in a defin...
Deciphering the age-dependent changes of pulmonary fibroblasts in mice by single-cell transcriptomics
Deciphering the age-dependent changes of pulmonary fibroblasts in mice by single-cell transcriptomics
Background and objectives: The heterogeneity of pulmonary fibroblasts, a critical aspect of both murine and human models u...
Biology of melanocytes in mammals
Biology of melanocytes in mammals
Melanocytes, which originate from the neuroectoderm, are specialized cells responsible for producing pigments and possessi...
Heparanase contributes to pancreatic carcinoma progression through insulin-dependent glucose uptake
Heparanase contributes to pancreatic carcinoma progression through insulin-dependent glucose uptake
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive tumor, which is highly resistant to existing therapies and charac...
Lost in mTORC1-related translation limits healing, repair and regeneration in mammals
Lost in mTORC1-related translation limits healing, repair and regeneration in mammals
It is clear from an evolutionary perspective that some species are endowed with extreme regenerative capacity, while other...
The effects of semaphorin 3A in bone and cartilage metabolism: fundamental mechanism and clinical potential
The effects of semaphorin 3A in bone and cartilage metabolism: fundamental mechanism and clinical potential
Semaphorin 3A (Sema3A) is a neuroinformatic protein molecule with widespread expression across various tissues and organs....
Quercetin improves and protects Calu-3 airway epithelial barrier function
Quercetin improves and protects Calu-3 airway epithelial barrier function
Introduction: In light of the impact of airway barrier leaks in COVID-19 and the significance of vitamin D in COVID-19 out...
Circular RNAs: emerging players in asthma and COPD
Circular RNAs: emerging players in asthma and COPD
Circular RNAs (circRNAs) belong to a unique class of endogenously expressed non-protein-coding RNAs with a distinct circul...
Editorial: Cuproptosis and tumor
Editorial: Cuproptosis and tumor
As a trace element, copper is widely involved in the physiological activities of cells and plays an 26 important role. Due...
Envisioning a role for nuclear actin in prophase I spermatocytes
Envisioning a role for nuclear actin in prophase I spermatocytes
Actin is a multi-functional protein that is involved in numerous cellular processes including cytoskeleton regulation, cel...
Harnessing mechanobiology for kidney organoid research
Harnessing mechanobiology for kidney organoid research
Recently, organoids have emerged as revolutionizing tools with the unprecedented potential to recreate organ-specific micr...