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Multicellular 3D models to study myocardial ischemia–reperfusion injury
1 IntroductionMyocardial ischemia–reperfusion injury (IRI) refers to the cellular damage or dysfunction of cardiac tissue ...
Evaluation of mesenchymal stem cells as an in vitro model for inherited retinal diseases
1 IntroductionThe mammalian retina is a structurally complex compartment of the eye, consisting of over 60 types of cells ...
Corrigendum: Advances in understanding the regulation of pluripotency fate transition in embryonic stem cells
INTRODUCTIONTotipotent stem cells typically refer to fertilized eggs and blastomeres of 2-cell embryos formed following fe...
Targeting regulated cell death pathways in cancers for effective treatment: a comprehensive review
1 IntroductionCancer, an intricate disease characterized by uncontrolled cell proliferation and evasion of regulated cell ...
Chromosome alignment and Kif18A action rely on spindle-localized control of Cdk1 activity
IntroductionDuring mitosis, proper chromosome alignment at the equator of the mitotic spindle at metaphase grants synchron...
Adhesive chitosan-based hybrid biohydrogels for peripheral nerve injury repair
1 IntroductionWith the increasing number of traffic accidents, medical accidents, and the rapid expansion of mechanized pr...
Comparison of two UPS regulators: the 26S proteasome LID and the COP9 signalosome
In this opinion we would like to compare two essential regulators of the ubiquitin proteasome system: The 26S proteasome (...
Corrigendum: Integrated analysis of single-cell and bulk RNA sequencing data reveals a cellular senescence-related signature in hepatocellular carcinoma
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Editorial: Glial crosstalk in neurological disorders
consensus on the involvement of non-neuronal cells in the pathological progression. Recently, glial cells are getting atte...
Contribution of the paternal histone epigenome to the preimplantation embryo
Introduction – advancements in epigeneticsOur knowledge of the genome has advanced significantly during the twenty-first c...
Insights into the pathogenesis of gestational and hepatic diseases: the impact of ferroptosis
1 IntroductionProgrammed cell death (PCD) is a genetically regulated process essential for maintaining body homeostasis an...
Advances in the structure and function of the nucleolar protein fibrillarin
1 IntroductionIn 1985, a single protein band with a molecular weight of 34 kDa and a pI of 8.5 was identified through immu...
Significance of exosomes in osteosarcoma research: a systematic review and meta-analysis of a singular clinical investigation
1 IntroductionOsteosarcoma ranks first among all bone-related primary malignant tumors, with a reported incidence of about...
Vascular endothelial growth factor facilitates the effects of telocytes on tumor cell proliferation and migration
IntroductionTelocytes (TCs) are a population of interstitial cells that were newly identified and officially named by the ...
Cumulus cell DNA damage linked to fertilization success in females with an ovulatory dysfunction phenotype
Front. Cell Dev. Biol., 13 November 2024 Sec. Molecular and Cellular Reproduction Disclaimer: All ...
Overexpression of Lifeact in the C. elegans body wall muscle causes sarcomere disorganization and embryonic or larval lethality
IntroductionActin is one of the major cytoskeletal proteins and it plays important roles in many cell biological events (P...
Enhanced T-cell activation and chemokine-associated function in CD14-positive cells from venous sinus blood in sub-acute cerebral venous sinus thrombosis
1 IntroductionCerebral venous sinus thrombosis (CVST) accounts for 0.5%–1% of all strokes and occurs mainly in young femal...
Editorial: Phosphorylation-dependent peptidyl-prolyl cis/trans isomerase PIN1 - volume II
underlying PIN1-mediated signaling pathways and explores the therapeutic implications of targeting PIN1 in disease interve...
The function of histone methyltransferase SETDB1 and its roles in liver cancer
1 IntroductionHepatocellular carcinoma (HCC) is one of the most common malignant tumors, and it is also one of the most co...
Epithelial-mesenchymal crosstalk: the scriptwriter of craniofacial morphogenesis
1 IntroductionOrofacial clefts (OFC), including cleft lip and cleft palate, are one of the most common birth defects with ...
Deciphering transcriptome patterns in porcine mesenchymal stem cells promoting phenotypic maintenance and differentiation by key driver genes
1 IntroductionMesenchymal stem cells (MSC) are adult stem cells with characteristic proliferative and differentiation capa...
Combining external physical stimuli and nanostructured materials for upregulating pro-regenerative cellular pathways in peripheral nerve repair
Peripheral nerve repair remains a major clinical challenge, particularly in the pursuit of therapeutic approaches that ens...
Research progress on S-palmitoylation modification mediated by the ZDHHC family in glioblastoma
1 IntroductionS-palmitoylation is a highly conserved post-translational lipid modification widely present in eukaryotes. I...
Role of ABCC5 in cancer drug resistance and its potential as a therapeutic target
IntroductionAs the second leading cause of global mortality, cancer accounted for 600,000 deaths in the United States in 2...
PtosisDiffusion: a training-free workflow for precisely predicting post-operative appearance in blepharoptosis patients based on diffusion models
1 IntroductionBlepharoptosis (Ptosis) is characterized by an abnormally low upper eyelid margin in the primary gaze, which...
Editorial: Unlocking the potential of cell therapy: exploring cell types, induction methods, and culture techniques
Culture, Immunotherapy, Mesenchymal Stromal Cells (MSCs), Gene Editing, Bioreactor Systems, Regenerative Medicine Cell the...
Human decidua basalis mesenchymal stem/stromal cells enhance anticancer properties of human natural killer cells, in vitro
IntroductionWe have previously reported isolation and characterization of mesenchymal stem cells/stromal cells (MSCs) from...
Unveiling the dynamics of circulating tumor cells in colorectal cancer: from biology to clinical applications
1 IntroductionColorectal cancer (CRC) ranks among the most diagnosed malignancies worldwide, with a substantial impact on ...
Chemical approaches targeting the hurdles of hepatocyte transplantation: mechanisms, applications, and advances
Highlights1. Small molecule modulation of signaling pathways (e.g., Wnt, TGF-beta, HGF) and epigenetic profiles can promot...
Enhancing human capillary tube network assembly and maturation through upregulated expression of pericyte-derived TIMP-3
IntroductionDespite their importance, capillaries are an understudied blood vessel type. They are thinly fragile, very num...
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