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Emerging technologies in personalized medicine
Volume 91, June 2023, 101182Author links open overlay panelAbstractA variety of technologies are emerging to help clinicia...
Non-canonical roles of Siglecs: Beyond sialic acid-binding and immune cell modulation
Volume 90, April 2023, 101145Author links open overlay panelAbstractSiglecs (Sialic acid-binding immunoglobulin-type lecti...
The evolving regulatory landscape in regenerative medicine
Volume 91, June 2023, 101138Author links open overlay panelAbstractRegenerative medicine as a field has emerged as a new c...
Systems to model the personalized aspects of microbiome health and gut dysbiosis
Volume 91, June 2023, 101115Author links open overlay panelAbstractThe human gut microbiome is a complex and dynamic micro...
In vitro high-content tissue models to address precision medicine challenges
Volume 91, June 2023, 101108Author links open overlay panelAbstractThe field of precision medicine allows for tailor-made ...
Bioactives and human health
Available online 5 January 2023, 101168Author links open overlay panelCesar G.FragaPersonEnvelopePatricia I.OteizaShow mor...
Extracellular vesicles in the glioblastoma microenvironment: A diagnostic and therapeutic perspective
Available online 27 December 2022, 101167Author links open overlay panelAbstractGlioblastoma (GBM), is the most malignant ...
(Poly)phenols and nitrolipids: Relevant participants in nitric oxide metabolism
Available online 12 December 2022, 101158Author links open overlay panelAbstractNitric oxide (•NO) is an essential molecul...
Editorial on proteases in health and disease
Volume 88, December 2022, 101160Author links open overlay panelBorisTurk(Guest executive editor)abPersonEnvelopeShow moreN...
Extracellular vesicles as personalized medicine
Available online 28 November 2022, 101155Author links open overlay panelAbstractExtracellular vesicles (EVs) are released ...
Viral proteases as therapeutic targets
Volume 88, December 2022, 101159Author links open overlay panelAbstractSome medically important viruses―including retrovir...
Proteostasis in aging-associated ocular disease
Volume 88, December 2022, 101157Author links open overlay panelAbstractVision impairment has devastating consequences for ...
Phenotypic screening models for rapid diagnosis of genetic variants and discovery of personalized therapeutics
Available online 18 November 2022, 101153Author links open overlay panelAbstractPrecision medicine strives for highly indi...
Anthocyanin actions at the gastrointestinal tract: Relevance to their health benefits
Available online 12 November 2022, 101156AbstractAnthocyanins (AC) are flavonoids abundant in the human diet, which consum...
Anatomical biology guides a search for nutrients for the aging brain
Available online 10 November 2022, 101154AbstractConsiderable evidence has established the importance of specific nutrient...
Beyond target cell death – Granzyme serine proteases in health and disease
Volume 88, December 2022, 101152AbstractGranzymes are a family of small (∼32 kDa) serine proteases with a range of substra...
Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics
Available online 28 October 2022, 101151AbstractWith more than 5 million fatalities and close to 300 million reported case...
Cysteine cathepsins: A long and winding road towards clinics
Volume 88, December 2022, 101150AbstractBiomedical research often focuses on properties that differentiate between disease...
RNA interference (RNAi)-based therapeutics for treatment of rare neurologic diseases
Available online 17 October 2022, 101148AbstractAdvances in genome sequencing have greatly facilitated the identification ...
Perspectives for the application of neurogenetic research in programming Neurorehabilitation
Available online 15 October 2022, 101149AbstractCertain genetic variants underlie the proper functioning of the nervous sy...
Siglecs in health and disease
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Revisiting the bioavailability of flavan-3-ols in humans: A systematic review and comprehensive data analysis
This systematic review summarizes findings from human studies investigating the different routes of absorption, metabolism...
Diagnostic and therapeutic potential of protease inhibition
Volume 88, December 2022, 101144AbstractProteases are enzymes that hydrolyze peptide bonds in proteins and peptides; thus,...
The subversion of toll-like receptor signaling by bacterial and viral proteases during the development of infectious diseases
Volume 88, December 2022, 101143AbstractToll-like receptors (TLRs) are pattern recognition receptors (PRRs) that respond t...
Data structuring may prevent ambiguity and improve personalized medical prognosis
Topics expected to influence personalized medicine (PM), where medical decisions, practices, and treatments are tailored t...
Roles of Siglecs in neurodegenerative diseases
Available online 9 September 2022, 101141AbstractMicroglia are resident myeloid cells in the central nervous system (CNS) ...
Impact of Siglecs on autoimmune diseases
Available online 30 August 2022, 101140AbstractAutoimmune diseases affect tens of millions of people just in the United St...
Measuring the intake of dietary bioactives: Pitfalls and how to avoid them
Available online 26 August 2022, 101139AbstractBioactives are food constituents that, while not essential to human life, c...
Discovery, classification, evolution and diversity of Siglecs
Available online 18 August 2022, 101117AbstractImmunoglobulin (Ig) superfamily proteins play diverse roles in vertebrates,...
Role of Siglecs in viral infections: A double-edged sword interaction
Available online 16 August 2022, 101113AbstractSialic-acid-binding immunoglobulin-like lectins are cell surface immune rec...
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