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A retrospective cohort study of coagulation function in patients with liver cirrhosis receiving cefoperazone/sulbactam with and without vitamin K1 supplementation
A retrospective cohort study of coagulation function in patients with liver cirrhosis receiving cefoperazone/sulbactam with and without vitamin K1 supplementation
Cefoperazone/sulbactam is commonly prescribed for the treatment of infected patients with cirrhosis. To investigate the ef...
Assessing the cost-effectiveness of replacing antimetabolites with mTOR inhibitors in heart transplant immunosuppression in China: a network meta-analysis-based economic evaluation
Assessing the cost-effectiveness of replacing antimetabolites with mTOR inhibitors in heart transplant immunosuppression in China: a network meta-analysis-based economic evaluation
Although several pharmacoeconomic studies have assessed the cost-effectiveness of maintenance immunosuppressive regimens f...
Cost-effectiveness analysis of tislelizumab plus chemotherapy versus standard chemotherapy in first-line treatment for extensive-stage small cell lung cancer: perspectives from the United States and China
Cost-effectiveness analysis of tislelizumab plus chemotherapy versus standard chemotherapy in first-line treatment for extensive-stage small cell lung cancer: perspectives from the United States and China
Tislelizumab combined with chemotherapy has shown significant clinical benefits in improving overall survival compared to ...
Effectiveness and safety of remimazolam tosilate versus propofol for sedation in patients undergoing gastrointestinal endoscopy: a randomized controlled trial
Effectiveness and safety of remimazolam tosilate versus propofol for sedation in patients undergoing gastrointestinal endoscopy: a randomized controlled trial
Remimazolam tosilate is a new type of benzodiazepine currently used for gastrointestinal endoscopy and can be combined wit...
Efficacy and safety of tirzepatide versus placebo in overweight or obese adults without diabetes: a systematic review and meta-analysis of randomized controlled trials
Efficacy and safety of tirzepatide versus placebo in overweight or obese adults without diabetes: a systematic review and meta-analysis of randomized controlled trials
Tirzepatide was approved to treat type 2 diabetes and obesity, but its efficacy and safety in patients without diabetes ha...
Communication issues between pharmacists and d/Deaf people: a qualitative study in Thailand
Communication issues between pharmacists and d/Deaf people: a qualitative study in Thailand
People who are d/Deaf face challenges when communicating with pharmacists, especially during medication counseling. This s...
The usage of anticholinergic medications in a low- and middle-income country: a longitudinal comparison of 2013–15 and 2020–22 datasets
The usage of anticholinergic medications in a low- and middle-income country: a longitudinal comparison of 2013–15 and 2020–22 datasets
While the effects of anticholinergic drug use have been increasingly highlighted, trends in anticholinergic use remain poo...
Appropriateness of intravenous fluid prescriptions in hospitalised patients: a point prevalence study
Appropriateness of intravenous fluid prescriptions in hospitalised patients: a point prevalence study
Inappropriate use of intravenous (IV) fluids results in fluid overload, electrolyte disturbances, and increased costs. To ...
Exploring the suitability of a ward-based clinical pharmacy activity collection tool for ambulatory care practice: a mixed-methods study
Exploring the suitability of a ward-based clinical pharmacy activity collection tool for ambulatory care practice: a mixed-methods study
At a London-based hospital, a validated ward-based clinical pharmacy activity collection tool has been used to monitor act...
Desprescribing antihypertensives in older people in primary care: subgroup analysis of the MINOR randomised clinical trial
Desprescribing antihypertensives in older people in primary care: subgroup analysis of the MINOR randomised clinical trial
Polypharmacy is often required for older adults with hypertension, and excessive treatment is associated with a high risk ...
Cardiac adverse events associated with statins in myocardial infarction patients: a pharmacovigilance analysis of the FDA Adverse Event Reporting System
Cardiac adverse events associated with statins in myocardial infarction patients: a pharmacovigilance analysis of the FDA Adverse Event Reporting System
Despite the advent of new pharmacotherapies, statins remain a cornerstone in the secondary prevention of myocardial infarc...
Short-term outcome of personalized theory-based pharmaceutical care service on the medication administration problems of family caregivers: a pre-post intervention study
Short-term outcome of personalized theory-based pharmaceutical care service on the medication administration problems of family caregivers: a pre-post intervention study
Family caregivers face many problems during administration of medications. Pharmacists are reliable and accessible healthc...
Model-informed precision dosing of vancomycin in clinical practice: an intervention development study
Model-informed precision dosing of vancomycin in clinical practice: an intervention development study
Current guidelines recommend dosing vancomycin based on the area under the concentration time curve (AUC) to maximise effi...
A cross-sectional study of recent patterns of psychotropic medication use in children and adolescents in Ireland
A cross-sectional study of recent patterns of psychotropic medication use in children and adolescents in Ireland
There has been a global rise in prescribing of psychotropic medications. Variations in patterns of use, according to age, ...
Predicting survival benefits of immune checkpoint inhibitor therapy in lung cancer patients: a machine learning approach using real-world data
Predicting survival benefits of immune checkpoint inhibitor therapy in lung cancer patients: a machine learning approach using real-world data
Due to the heterogeneity in the effectiveness of immunotherapy for lung cancer, identifying predictors is crucial. This st...
Disproportionality analysis of flutamide- or bicalutamide-induced liver injury with and without steroids by using the Japanese Adverse Drug Event Report database
Disproportionality analysis of flutamide- or bicalutamide-induced liver injury with and without steroids by using the Japanese Adverse Drug Event Report database
Although the mechanism underlying flutamide- or bicalutamide-induced liver injury may be immune related, the details remai...
Pharmacists’ empathy after a postgraduate course in narrative medicine: an observational study
Pharmacists’ empathy after a postgraduate course in narrative medicine: an observational study
Narrative medicine is a recent cross-disciplinary approach which through aesthetic activities such as reading fiction and ...
The effect of clinical pharmacist-led pharmaceutical care services on medication adherence, clinical outcomes and quality of life in patients with stroke: a randomised controlled trial
The effect of clinical pharmacist-led pharmaceutical care services on medication adherence, clinical outcomes and quality of life in patients with stroke: a randomised controlled trial
Stroke is a major cause of morbidity and mortality worldwide. Pharmaceutical care services play a significant role in mana...
Addressing the second victim phenomenon among community pharmacists and its impact on clinical pharmacy practice: a consensus study
Addressing the second victim phenomenon among community pharmacists and its impact on clinical pharmacy practice: a consensus study
The second victim phenomenon, denoting the harmful effects of patient safety incidents on healthcare practitioners, remain...
Sentiment analysis in medication adherence: using ruled-based and artificial intelligence-driven algorithms to understand patient medication experiences
Sentiment analysis in medication adherence: using ruled-based and artificial intelligence-driven algorithms to understand patient medication experiences
Studies are exploring ways to improve medication adherence, with sentiment analysis (SA) being an underutilized innovation...
Exploring the impact of baseline platelet count on linezolid-induced thrombocytopenia: a retrospective single-center observation study
Exploring the impact of baseline platelet count on linezolid-induced thrombocytopenia: a retrospective single-center observation study
Patients treated with linezolid (LZD) frequently develop thrombocytopenia, and previous studies have identified the risk f...
Translation and validation of the CLEO tool in Vietnamese to assess the significance of pharmacist interventions
Translation and validation of the CLEO tool in Vietnamese to assess the significance of pharmacist interventions
There is currently no validated tool available for assessing the potential significance of pharmacist interventions in Vie...
Association of polypharmacy with clinical outcomes and healthcare utilization in older adults with cardiometabolic diseases: a retrospective cohort study
Association of polypharmacy with clinical outcomes and healthcare utilization in older adults with cardiometabolic diseases: a retrospective cohort study
Limited knowledge exists on the association between polypharmacy among older patients diagnosed with cardiometabolic disea...
Cost-effectiveness analysis of selpercatinib versus chemotherapy and pembrolizumab in the first-line treatment of rearranged during transfection fusion–positive non-small cell lung cancer in the United States
Cost-effectiveness analysis of selpercatinib versus chemotherapy and pembrolizumab in the first-line treatment of rearranged during transfection fusion–positive non-small cell lung cancer in the United States
Although selpercatinib has shown clinical benefits for rearranged during transfection (RET) fusion–positive non-smal...
Measuring the impact of pharmaceutical care bundle delivery on patient outcomes: an observational study
Measuring the impact of pharmaceutical care bundle delivery on patient outcomes: an observational study
Clinical pharmacists perform activities to optimise medicines use and prevent patient harm. Historically, clinical pharmac...
A qualitative, theory-based exploration of facilitators and barriers for implementation of pharmacist prescribing in chronic kidney disease
A qualitative, theory-based exploration of facilitators and barriers for implementation of pharmacist prescribing in chronic kidney disease
While there is an accumulation of evidence that pharmacist prescribing is safe and effective, there is a lack of research ...
Ethical conflicts in patient care situations of community pharmacists: a cross-sectional online survey
Ethical conflicts in patient care situations of community pharmacists: a cross-sectional online survey
Community pharmacy practice is rarely considered in ethical research, although various ethical conflicts are known for thi...
Group-based trajectory modeling to identify adherence patterns for direct oral anticoagulants in Medicare beneficiaries with atrial fibrillation: a real-world study on medication adherence
Group-based trajectory modeling to identify adherence patterns for direct oral anticoagulants in Medicare beneficiaries with atrial fibrillation: a real-world study on medication adherence
Suboptimal adherence to direct oral anticoagulants (DOACs) among atrial fibrillation (AF) patients remains currently a maj...
Post-marketing pharmacovigilance study of inclisiran: mining and analyzing adverse event data from the FDA Adverse Event Reporting System database
Post-marketing pharmacovigilance study of inclisiran: mining and analyzing adverse event data from the FDA Adverse Event Reporting System database
Inclisiran, the newest lipid-lowering drug, has not shown significant safety problems in major clinical studies. However, ...
Implementation and evaluation of pharmacist-led heart failure diagnostic and guideline directed medication therapies clinic
Implementation and evaluation of pharmacist-led heart failure diagnostic and guideline directed medication therapies clinic
Timely diagnosis of heart failure (HF) and rapid optimisation of guideline-directed medication therapy (GDMT) improves pat...
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