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Statins mediate anti- and pro-tumourigenic functions by remodelling the tumour microenvironment
Cell surface marker and intracellular SPC expression was analysed by flow cytome...
MEK-inhibitor-mediated rescue of skeletal myopathy caused by activating Hras mutation in a Costello syndrome mouse model
The Ras pathway is a well-studied signal transduction pathway i...
First person – Jun-yi Zhu and Xiaohu Huang
First Person is a series of interviews with the first authors o...
Pharmacological or genetic inhibition of hypoxia signaling attenuates oncogenic RAS -induced cancer phenotypes
In this study, we generated a new KRASG12V leukemia model in Drosophila by expre...
Biology, technology and a bit of serendipity: an interview with Shiva Malek
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Selective disruption of trigeminal sensory neurogenesis and differentiation in a mouse model of 22q11.2 deletion syndrome
E9.5 and E10.5 embryos were immersion fixed and prepared for cryosectioning and ...
Tissue architecture delineates field cancerization in BRAF V600E -induced tumor development
The cell of origin in differentiated thyroid cancer – the folli...
First person – Elin Schoultz and Ellen Johansson
First Person is a series of interviews with the first authors o...
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