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Orexin and Sleep Disturbances in Alpha-Synucleinopathies: a Systematic Review
Orexin and Sleep Disturbances in Alpha-Synucleinopathies: a Systematic Review
Sleep disturbances are amongst most frequent non-motor symptoms of Parkinson’s Disease (PD), and they are similarly ...
Short-Term Impact of Seizures and Mitigation Opportunities
Short-Term Impact of Seizures and Mitigation Opportunities
The burden of epilepsy is complex and consists of elements directly related to acute seizures as well as those associated ...
Artificial Intelligence and Multiple Sclerosis
Artificial Intelligence and Multiple Sclerosis
In this paper, we analyse the different advances in artificial intelligence (AI) approaches in multiple sclerosis (MS). AI...
De-escalation and Discontinuation of Disease-Modifying Therapies in Multiple Sclerosis
De-escalation and Discontinuation of Disease-Modifying Therapies in Multiple Sclerosis
Long-term use of multiple sclerosis (MS) disease-modifying therapies (DMTs) is standard practice to prevent accumulation o...
Improving Quality of Care for Status Epilepticus: Putting Protocols into Practice
Improving Quality of Care for Status Epilepticus: Putting Protocols into Practice
Timely treatment of status epilepticus (SE) improves outcomes, however gaps between recommended and implemented care are c...
Patient-Centered Management of Brain Tumor-Related Epilepsy
Patient-Centered Management of Brain Tumor-Related Epilepsy
Brain tumor-related epilepsy is a heterogenous syndrome involving variability in incidence, timing, pathophysiology, and c...
Sleep Symptoms in Migraine
Sleep Symptoms in Migraine
To review replicated and highlight novel studies of sleep in children and adults with episodic and chronic migraine. Attac...
Maculopapillary Bundle Degeneration in Optic Neuropathies
Maculopapillary Bundle Degeneration in Optic Neuropathies
Degeneration of the maculopapillary bundle (MPB) is a prominent feature in a spectrum of optic neuropathies. MPB-selective...
Surgical Management of Headache Disorders - A Systematic Review of the Literature
Surgical Management of Headache Disorders - A Systematic Review of the Literature
This review article critically evaluates the latest advances in the surgical treatment of headache disorders. Studies have...
MOG Antibody Disease: Nuances in Presentation, Diagnosis, and Management
MOG Antibody Disease: Nuances in Presentation, Diagnosis, and Management
Myelin oligodendrocyte glycoprotein antibody disease (MOGAD) is a distinct neuroinflammatory condition characterized by at...
Epidemiology of Parkinson’s Disease: An Update
Epidemiology of Parkinson’s Disease: An Update
In recent decades, epidemiological understanding of Parkinson disease (PD) has evolved significantly. Major discoveries in...
Immune-Mediated Necrotizing Myopathies: Current Landscape
Immune-Mediated Necrotizing Myopathies: Current Landscape
Immune-mediated necrotizing myopathy (IMNM), characterized by acute or subacute onset, severe weakness, and elevated creat...
Strategies to Improve Drug Delivery Across the Blood–Brain Barrier for Glioblastoma
Strategies to Improve Drug Delivery Across the Blood–Brain Barrier for Glioblastoma
Glioblastoma remains resistant to most conventional treatments. Despite scientific advances in the past three decades, the...
Recent Advances in Clinical Trials in Multiple System Atrophy
Recent Advances in Clinical Trials in Multiple System Atrophy
This review summarizes previous and ongoing neuroprotection trials in multiple system atrophy (MSA), a rare and fatal neur...
The Impact of Aging on Multiple Sclerosis
The Impact of Aging on Multiple Sclerosis
Multiple sclerosis (MS) is a chronic, immune-mediated demyelinating disorder of the central nervous system. Age is one of ...
Interpretation of the Visual Field in Neuro-ophthalmic Disorders
Interpretation of the Visual Field in Neuro-ophthalmic Disorders
In this review, we will describe current methods for visual field testing in neuro-ophthalmic clinical practice and resear...
Advantages and Pitfalls of the Use of Optical Coherence Tomography for Papilledema
Advantages and Pitfalls of the Use of Optical Coherence Tomography for Papilledema
Papilledema refers to optic disc swelling caused by raised intracranial pressure. This syndrome arises from numerous poten...
Lobar Microbleeds in the Posterior Cortical Atrophy Syndrome: A Comparison to Typical Alzheimer’s Disease
Lobar Microbleeds in the Posterior Cortical Atrophy Syndrome: A Comparison to Typical Alzheimer’s Disease
Posterior cortical atrophy is a clinico-radiographical syndrome that presents with higher-order visual dysfunction and is ...
Updated Response Assessment in Neuro-Oncology (RANO) for Gliomas
Updated Response Assessment in Neuro-Oncology (RANO) for Gliomas
The response assessment in Neuro-Oncology (RANO) criteria and its versions were developed by expert opinion consensus to s...
Magnetoencephalography for Epilepsy Presurgical Evaluation
Magnetoencephalography for Epilepsy Presurgical Evaluation
Magnetoencephalography (MEG) is a functional neuroimaging technique that records neurophysiology data with millisecond tem...
Hormonal Therapies in Multiple Sclerosis: a Review of Clinical Data
Hormonal Therapies in Multiple Sclerosis: a Review of Clinical Data
Given the potential for exogenous hormones to influence risk and course of MS, this narrative review aims to summarize cur...
Neuromodulation for Post-Stroke Motor Recovery: a Narrative Review of Invasive and Non‑Invasive Tools
Neuromodulation for Post-Stroke Motor Recovery: a Narrative Review of Invasive and Non‑Invasive Tools
Stroke remains a leading disabling condition, and many survivors have permanent disability despite acute stroke treatment ...
Neural Control of REM Sleep and Motor Atonia: Current Perspectives
Neural Control of REM Sleep and Motor Atonia: Current Perspectives
Since the formal discovery of rapid eye movement (REM) sleep in 1953, we have gained a vast amount of knowledge regarding ...
Machine Learning and Artificial Intelligence Applications to Epilepsy: a Review for the Practicing Epileptologist
Machine Learning and Artificial Intelligence Applications to Epilepsy: a Review for the Practicing Epileptologist
Machine Learning (ML) and Artificial Intelligence (AI) are data-driven techniques to translate raw data into applicable an...
Exploring the Role of Locus Coeruleus in Alzheimer’s Disease: a Comprehensive Update on MRI Studies and Implications
Exploring the Role of Locus Coeruleus in Alzheimer’s Disease: a Comprehensive Update on MRI Studies and Implications
Performing a thorough review of magnetic resonance imaging (MRI) studies assessing locus coeruleus (LC) integrity in agein...
Vagus Nerve Stimulation in Ischemic Stroke
Vagus Nerve Stimulation in Ischemic Stroke
Vagus nerve stimulation (VNS) has emerged as a potential therapeutic approach for neurological and psychiatric disorders. ...
Neuromodulation for Post-Stroke Motor Recovery: a Narrative Review of Invasive of Invasive and Non‑Invasive Tools
Neuromodulation for Post-Stroke Motor Recovery: a Narrative Review of Invasive of Invasive and Non‑Invasive Tools
Stroke remains a leading disabling condition, and many survivors have permanent disability despite acute stroke treatment ...
Revisiting Functional Dysconnectivity: a Review of Three Model Frameworks in Schizophrenia
Revisiting Functional Dysconnectivity: a Review of Three Model Frameworks in Schizophrenia
Over the last decade, evidence suggests that a combination of behavioral and neuroimaging findings can help illuminate cha...
Neurotoxicity of Cancer Immunotherapies Including CAR T Cell Therapy
Neurotoxicity of Cancer Immunotherapies Including CAR T Cell Therapy
To outline the spectrum of neurotoxicity seen with approved immunotherapies and in pivotal clinical trials including immun...