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Predominant affective temperaments in depressive patients with severe social withdrawal
Predominant affective temperaments in depressive patients with severe social withdrawal
Hikikomori (HK) is characterized by self-isolation and social refusal, being more likely also associated with affective di...
Impacts of metabolic disruption, body mass index and inflammation on cognitive function in post-COVID-19 condition: a randomized controlled trial on vortioxetine
Impacts of metabolic disruption, body mass index and inflammation on cognitive function in post-COVID-19 condition: a randomized controlled trial on vortioxetine
Post-COVID-19 Condition (PCC), as defined by the World Health Organization (WHO), currently lacks any regulatory-approved ...
Causal links between sedentary behavior, physical activity, and psychiatric disorders: a Mendelian randomization study
Causal links between sedentary behavior, physical activity, and psychiatric disorders: a Mendelian randomization study
Studies suggest a correlation between excessive sedentary behavior, insufficient physical activity, and an elevated likeli...
Clarification of the molecular mechanisms underlying glyphosate-induced major depressive disorder: a network toxicology approach
Clarification of the molecular mechanisms underlying glyphosate-induced major depressive disorder: a network toxicology approach
Major depressive disorder (MDD) is predicted to become the second most common cause of disability in the near future. Expo...
Analyzing the psychometric properties of the PHQ-9 using item response theory in a Chinese adolescent population
Analyzing the psychometric properties of the PHQ-9 using item response theory in a Chinese adolescent population
People are more likely to fall victim to depression during adolescence since it is a period of rapid biopsychosocial trans...
On mental pain and suicide risk in modern psychiatry
On mental pain and suicide risk in modern psychiatry
Facing suicide risk is probably the most difficult task for clinicians when dealing with patients in crisis. It requires p...
Occurrences of post-traumatic stress disorder, anxiety, depression, and burnout syndrome in ICU staff workers after two-year of the COVID-19 pandemic: the international PSY-CO in ICU study
Occurrences of post-traumatic stress disorder, anxiety, depression, and burnout syndrome in ICU staff workers after two-year of the COVID-19 pandemic: the international PSY-CO in ICU study
The present study aimed at assessing the prevalences of post-traumatic stress disorder (PTSD) (main objective), anxiety, d...
Weight change following diagnosis with psychosis: a retrospective cohort study in Greater Manchester, UK
Weight change following diagnosis with psychosis: a retrospective cohort study in Greater Manchester, UK
Weight gain in the months/years after diagnosis/treatment of severe enduring mental illness (SMI) is a major predictor of ...
Predictors of antipsychotics switching among ambulatory patients with schizophrenia in Ethiopia: a multicenter hospital-based cross-sectional study
Predictors of antipsychotics switching among ambulatory patients with schizophrenia in Ethiopia: a multicenter hospital-based cross-sectional study
A change of therapy from one to another antipsychotic medication is currently the main challenge of therapy. This study ai...
Effect of perceived stigma on work and social roles among individuals with mental health disorders in Saudi Arabia: findings from a national survey
Effect of perceived stigma on work and social roles among individuals with mental health disorders in Saudi Arabia: findings from a national survey
It is known worldwide that stigma towards mental illness exists. Studies on stigma perceived by patients with mental illne...
Mendelian randomization studies of depression: evidence, opportunities, and challenges
Mendelian randomization studies of depression: evidence, opportunities, and challenges
Major depressive disorder (MDD) poses a significant social and economic burden worldwide. Identifying exposures, risk fact...
Discontinuation of antidepressant treatment: a retrospective cohort study on more than 20,000 participants
Discontinuation of antidepressant treatment: a retrospective cohort study on more than 20,000 participants
Factors influencing antidepressant treatment discontinuation are poorly understood. In the present study, we aimed to esti...
Nationwide consensus on the clinical management of treatment-resistant depression in Italy: a Delphi panel
Nationwide consensus on the clinical management of treatment-resistant depression in Italy: a Delphi panel
Treatment-resistant depression (TRD) is defined by the European Medicines Agency as a lack of clinically meaningful improv...
Borderline personality disorder and early psychosis: a narrative review
Borderline personality disorder and early psychosis: a narrative review
The purpose of the present review was to summarize the main literature contribution on the relationship between borderline...
Randomized clinical trial of low dose suramin intravenous infusions for treatment of autism spectrum disorder
Randomized clinical trial of low dose suramin intravenous infusions for treatment of autism spectrum disorder
There is a critical need for effective treatment of the core symptoms of autism spectrum disorder (ASD). The purinergic an...
A shift in psychiatry through AI? Ethical challenges
A shift in psychiatry through AI? Ethical challenges
The digital transformation has made its way into many areas of society, including medicine. While AI-based systems are wid...
A multicenter, randomized controlled study on the efficacy of agomelatine in ameliorating anhedonia, reduced motivation, and circadian rhythm disruptions in patients with major depressive disorder (MDD)
A multicenter, randomized controlled study on the efficacy of agomelatine in ameliorating anhedonia, reduced motivation, and circadian rhythm disruptions in patients with major depressive disorder (MDD)
To evaluate the clinical efficacy and safety of Agomelatine in improving symptoms in patients with major depressive disord...
Psychometric properties of the Clinical Assessment Interview for Negative Symptoms (CAINS) in patients with depression and its relationship to affective symptoms
Psychometric properties of the Clinical Assessment Interview for Negative Symptoms (CAINS) in patients with depression and its relationship to affective symptoms
There is a conceptual overlap between negative and depressive symptoms, requiring further exploration to advance the under...
Stress, depression, anxiety, and quality of life among the healthcare workers during COVID-19 pandemic in Syria: a multi-center study
Stress, depression, anxiety, and quality of life among the healthcare workers during COVID-19 pandemic in Syria: a multi-center study
The COVID-19 pandemic emerged as an expected source of stress and anxiety as the healthcare workers had to work for long h...
DNMT1 SNPs (rs2114724 and rs2228611) associated with positive symptoms in Chinese patients with schizophrenia
DNMT1 SNPs (rs2114724 and rs2228611) associated with positive symptoms in Chinese patients with schizophrenia
Schizophrenia is a serious mental disorder with complex clinical manifestations, while its pathophysiological mechanism is...
The role of gut microbiota in the pathogenesis and treatment of postpartum depression
The role of gut microbiota in the pathogenesis and treatment of postpartum depression
Postpartum depression (PPD) is a common complication of pregnancy in women, and its pathogenesis mainly involves disturban...
Extrapyramidal adverse events and anticholinergics use after the long-term treatment of patients with schizophrenia with the new long-acting antipsychotic Risperidone ISM®: results from matching-adjusted indirect comparisons versus once-monthly formulations of Paliperidone palmitate and Aripiprazole monohydrate in 52-week studies
Extrapyramidal adverse events and anticholinergics use after the long-term treatment of patients with schizophrenia with the new long-acting antipsychotic Risperidone ISM®: results from matching-adjusted indirect comparisons versus once-monthly formulations of Paliperidone palmitate and Aripiprazole monohydrate in 52-week studies
Risperidone ISM® is a newly developed long-acting injectable (LAI) treatment for schizophrenia in adults. In the abse...
Role of trazodone in treatment of major depressive disorder: an update
Role of trazodone in treatment of major depressive disorder: an update
Major depressive disorder (MDD) is the most common mood disorder and a leading cause of disability worldwide. Trazodone, a...
Prevalence of mental disorders among middle school students in Shaoxing, China
Prevalence of mental disorders among middle school students in Shaoxing, China
In China, adolescents account for about a quarter of those treated for mental disorders each year, and adolescent mental h...
Autism and intention attribution test: a non-verbal evaluation with comic strips
Autism and intention attribution test: a non-verbal evaluation with comic strips
Despite autism spectrum disorder (ASD) and mentalization being two words often associated in the literature, the assessmen...
Prevalence of suicidal thoughts and attempts in the transgender population of the world: a systematic review and meta-analysis
Prevalence of suicidal thoughts and attempts in the transgender population of the world: a systematic review and meta-analysis
The aim of this meta-analysis was to determine global pooled prevalence of suicide thoughts and attempts in transgender po...
Effect of the decreased frequency of going out on the association between anxiety and sleep disorder during the COVID-19 pandemic: a mediation analysis
Effect of the decreased frequency of going out on the association between anxiety and sleep disorder during the COVID-19 pandemic: a mediation analysis
The objective of the present study was to examine the relationship between anxiety and sleep disorder during the COVID-19 ...
Gender differences in prevalence and associated factors of metabolic syndrome in first-treatment and drug-naïve schizophrenia patients
Gender differences in prevalence and associated factors of metabolic syndrome in first-treatment and drug-naïve schizophrenia patients
Metabolic syndromes (MetS) are clinical syndromes involving multiple pathological states with distinct gender-specific cli...
Sleep disorders related to index and comorbid mental disorders and psychotropic drugs
Sleep disorders related to index and comorbid mental disorders and psychotropic drugs
Mental disorders positively associate with sleep disorders. This study will explore the moderating influence of comorbid m...
The relationship between coping strategies with sexual satisfaction and sexual intimacy in women with multiple sclerosis
The relationship between coping strategies with sexual satisfaction and sexual intimacy in women with multiple sclerosis
Multiple sclerosis profoundly affects the sexual aspects of patients’ life, especially in women. Various coping stra...
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