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Green dialysis – let us talk about dialysis fluid.
Green dialysis – let us talk about dialysis fluid.
Background: Hemodialysis is one of the most resources consuming medical intervention. Due to its concept, the proper amoun...
Relationship between serial serum neutrophil-lymphocyte ratio, cardiovascular mortality, and all-cause mortality in Chinese peritoneal dialysis patients
Relationship between serial serum neutrophil-lymphocyte ratio, cardiovascular mortality, and all-cause mortality in Chinese peritoneal dialysis patients
Background It is believed that the excessive cardiovascular (CV) burden of patients on peritoneal dialysis (PD) is closely...
Unveiling the Unexpected: Why Doctors Should Look Beyond the Lungs When Predicting COVID-19 Mortality
Unveiling the Unexpected: Why Doctors Should Look Beyond the Lungs When Predicting COVID-19 Mortality
Introduction: The main objective of this study was to identify the best combination of admission day parameters for predic...
Vitamin D ameliorates podocyte injury by enhancing autophagy activity in diabetic kidney disease
Vitamin D ameliorates podocyte injury by enhancing autophagy activity in diabetic kidney disease
Introduction: Restoration of podocyte autophagy is considered as a feasible strategy for the treatment of diabetic kidney ...
Single-cell transcriptome sequencing reveals molecular mechanisms of renal injury in essential hypertension
Single-cell transcriptome sequencing reveals molecular mechanisms of renal injury in essential hypertension
Introduction: Hypertensive nephropathy is characterized by glomerular and tubulointerstitial damage, but we know little ab...
Polymorphisms of CARD9 Gene Predict Disease Progression and Renal Survival of Immunoglobulin A Nephropathy
Polymorphisms of CARD9 Gene Predict Disease Progression and Renal Survival of Immunoglobulin A Nephropathy
Introduction: A previous genome-wide association study has identified CARD9 (caspase recruitment domain family member 9) a...
Clinicopathological Characteristics and Outcomes of Immunoglobulin A Nephropathy with Different Types of Dyslipidemia: A Retrospective Single-Center Study
Clinicopathological Characteristics and Outcomes of Immunoglobulin A Nephropathy with Different Types of Dyslipidemia: A Retrospective Single-Center Study
<b><i>Introduction:</i></b> Immunoglobulin A nephropathy (IgAN) is one of the most common glomerul...
Novel metabolites to improve glomerular filtration rate estimation
Novel metabolites to improve glomerular filtration rate estimation
Introduction: The glomerular filtration rate (GFR) is crucial for chronic kidney disease (CKD) diagnosis and therapy. Vari...
Identification the genetic influence of SARS-CoV-2 infections on IgA nephropathy based on bioinformatics method.
Identification the genetic influence of SARS-CoV-2 infections on IgA nephropathy based on bioinformatics method.
Introduction: Coronavirus disease-2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2...
The long-term survival outcome in older patients with different pathological types of chronic kidney disease
The long-term survival outcome in older patients with different pathological types of chronic kidney disease
Introduction: Chronic kidney diseases (CKD) are prevalent in older people and renal pathological manifestations are import...
Klotho supplementation reverses renal dysfunction and interstitial fibrosis in remnant kidney.
Klotho supplementation reverses renal dysfunction and interstitial fibrosis in remnant kidney.
Introduction: While recent investigations show that klotho exerts reno-protective actions, it has not been fully addressed...
Methodology and Baseline Data of a Comparative Exploratory Double-Blinded Randomized Study of Intravenous Iron on Fibroblast Growth Factor 23 and Phosphate in Chronic Kidney Disease
Methodology and Baseline Data of a Comparative Exploratory Double-Blinded Randomized Study of Intravenous Iron on Fibroblast Growth Factor 23 and Phosphate in Chronic Kidney Disease
Modern intravenous iron compounds (e.g., ferric carboxymaltose [FCM] and ferric derisomaltose [FDI]) are utilized in the t...
International Variability of Renal and Cardiovascular Outcomes and Mortality in Patients with Type 2 Diabetes Mellitus in Europe
International Variability of Renal and Cardiovascular Outcomes and Mortality in Patients with Type 2 Diabetes Mellitus in Europe
<b><i>Introduction:</i></b> Type 2 diabetes and its complications represent a huge burden to publi...
Increased plasma homocysteine levels are associated with left ventricular hypertrophy in hypertensive patients with normal renal function.
Increased plasma homocysteine levels are associated with left ventricular hypertrophy in hypertensive patients with normal renal function.
Introduction: Renal function has an important bearing on plasma homocysteine levels. Plasma homocysteine is related to lef...
Urea reduction in acute kidney injury and mortality risk
Urea reduction in acute kidney injury and mortality risk
Introduction Urea is a toxin present in acute kidney injury (AKI). We hypothesize that reduction in serum urea levels migh...
Corticosteroid therapy in IgA Nephropathy: A friend or foe?
Corticosteroid therapy in IgA Nephropathy: A friend or foe?
Background: The administration of corticosteroids in addition to supportive care to delay progressive Immunoglobulin A nep...
Intra-renal and urinary glycogen synthase kinase 3 beta levels in diabetic and non-diabetic chronic kidney disease
Intra-renal and urinary glycogen synthase kinase 3 beta levels in diabetic and non-diabetic chronic kidney disease
Background Renal glycogen synthase kinase-3 beta (GSK3β) over-activity has been associated with a diverse range of kidney ...
Optimal renal artery-aorta angulation revealed by flow simulation
Optimal renal artery-aorta angulation revealed by flow simulation
Introduction In blood circulation, the vessel branching angle may have hemodynamic consequences. We hypothesized that ther...
Prevalence of cognitive impairment in peritoneal dialysis patients and associated factors
Prevalence of cognitive impairment in peritoneal dialysis patients and associated factors
Background. Cognitive impairment (CI) in patients with chronic kidney disease, including those treated with renal replacem...
Measurement of complement activation via plasma soluble C5b-9 comparison with terminal complement complex staining in a series of kidney biopsies
Measurement of complement activation via plasma soluble C5b-9 comparison with terminal complement complex staining in a series of kidney biopsies
Introduction: With the emergence of therapeutic complement inhibitors, there is a need to identify patients with complemen...
Serum 25(OH)D level is negatively associated with fatigue in elderly maintenance hemodialysis patients
Serum 25(OH)D level is negatively associated with fatigue in elderly maintenance hemodialysis patients
Introduction: Chronic kidney disease-mineral and bone disorder (CKD-MBD) is frequently observed in maintenance hemodialysi...
Aberrant Gut Microbiome Contributes to Barrier Dysfunction, Inflammation and Local Immune Responses in IgA Nephropathy
Aberrant Gut Microbiome Contributes to Barrier Dysfunction, Inflammation and Local Immune Responses in IgA Nephropathy
Introduction Numerous research have shown that serum Gal-deficient (Gd)-IgA1 levels are increased in IgA nephropathy (IgAN...
Clear Cell Renal Cell Carcinoma: A Comprehensive in Silico Study in Searching for Therapeutic Targets
Clear Cell Renal Cell Carcinoma: A Comprehensive in Silico Study in Searching for Therapeutic Targets
Introduction: Clear cell renal cell carcinoma is recognized as one of the leading causes of illness and death worldwide. U...
Correlation of renal oxygenation with renal function in chronic kidney disease: a preliminary prospective study
Correlation of renal oxygenation with renal function in chronic kidney disease: a preliminary prospective study
Introduction: Chronic hypoxia is prevalent in chronic kidney disease (CKD), and Blood oxygenation level-dependent magnetic...
AST-120 to target protein-bound uremic toxins improves cardiac output and kidney oxygenation in experimental chronic kidney disease.
AST-120 to target protein-bound uremic toxins improves cardiac output and kidney oxygenation in experimental chronic kidney disease.
Introduction Chronic kidney disease (CKD) is a global health problem with increasing incidence which is closely associated...
The Swiss Kidney Stone Cohort (SKSC), a longitudinal, multi-centric, observational cohort to study course and causes of kidney stone disease in Switzerland
The Swiss Kidney Stone Cohort (SKSC), a longitudinal, multi-centric, observational cohort to study course and causes of kidney stone disease in Switzerland
Introduction: Kidney stone disease has a high prevalence worldwide of approximately 10 % of the population and is characte...
GDF11 improves ischemia-reperfusion-induced acute kidney injury via regulating macrophage M1/M2 polarization
GDF11 improves ischemia-reperfusion-induced acute kidney injury via regulating macrophage M1/M2 polarization
Introduction: Acute kidney injury (AKI) is a clinical emergency caused by the rapid decline of renal function caused by va...
Biomarker-based prediction of survival and recovery of kidney function in acute kidney injury
Biomarker-based prediction of survival and recovery of kidney function in acute kidney injury
Background Acute kidney injury (AKI) affects increasing numbers of hospitalized patients, the prog-nosis remains poor. The...
Phospholipase A2 receptor antibodies and clinical prognosis in patients with idiopathic membranous nephropathy: an updated systematic review and meta-analysis
Phospholipase A2 receptor antibodies and clinical prognosis in patients with idiopathic membranous nephropathy: an updated systematic review and meta-analysis
Background: Idiopathic membranous nephropathy (IMN) is the most common form of primary nephrotic syndrome in adults. Antib...
Expression of Wilms’ Tumor 1 Antigen, Vimentin, and Corticotropin-Releasing Factor in the Human Kidney with Focal Segmental Glomerulosclerosis and Effect of Oxidative Stress on These Markers in HEK 293 Cells
Expression of Wilms’ Tumor 1 Antigen, Vimentin, and Corticotropin-Releasing Factor in the Human Kidney with Focal Segmental Glomerulosclerosis and Effect of Oxidative Stress on These Markers in HEK 293 Cells
<b><i>Introduction:</i></b> Wilms’ tumor 1 antigen (WT1) expression in podocytes has the important...
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