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The relationship of uremic toxin indoxyl sulfate and intestinal elimination mechanisms in hemodialysis patients
The relationship of uremic toxin indoxyl sulfate and intestinal elimination mechanisms in hemodialysis patients
Introduction: High indoxyl sulfate (IS) concentration is a serious problem for patients with CKD increasing the risk of ca...
LncRNA HOXA-AS2 facilitates prostate cancer progression by inhibiting miR-885-5p to upregulate KDM5B
LncRNA HOXA-AS2 facilitates prostate cancer progression by inhibiting miR-885-5p to upregulate KDM5B
Background: The regulatory network of competing endogenous RNAs (ceRNAs) affects tumorigenesis. In this study, we aimed to...
SIS3 alleviates cisplatin-induced acute kidney injury by regulating the lncRNA Arid2-IR-transferrin receptor pathway
SIS3 alleviates cisplatin-induced acute kidney injury by regulating the lncRNA Arid2-IR-transferrin receptor pathway
Introduction: TGF-β/Smad3 may be involved in the pathogenesis of acute kidney injury (AKI), but its functional role and me...
Diagnosis and course of membranous nephropathy in adults: comparison by age group
Diagnosis and course of membranous nephropathy in adults: comparison by age group
Introduction There have been few studies comparing younger and older adults with membranous nephropathy. The objective of ...
The impact of malnutrition, inflammation on cognitive impairment in hemodialysis patients-A multicenter study
The impact of malnutrition, inflammation on cognitive impairment in hemodialysis patients-A multicenter study
Introduction: Cognitive impairment is prevalent in patients undergoing hemodialysis (HD), which is related to the nutritio...
KLK4 silencing inhibits the growth of chromophobe renal cell carcinoma through ERK/AKT signaling pathway
KLK4 silencing inhibits the growth of chromophobe renal cell carcinoma through ERK/AKT signaling pathway
Introduction: Renal cell carcinoma (RCC) generally has a poor prognosis because of late diagnosis and metastasis. Despite ...
Should CKD EPI equation be used for estimation of glomerular filtration rate in obese subjects?
Should CKD EPI equation be used for estimation of glomerular filtration rate in obese subjects?
Introduction: Pandemic of obesity is strongly related to increase of chronic kidney disease (CKD) prevalence. Currently re...
Risk factors for arteriovenous fistula thrombus development: a systematic review and meta-analysis
Risk factors for arteriovenous fistula thrombus development: a systematic review and meta-analysis
Background: Risk factors like femal sex, fistula location, hypertension, albumin, diabetes, age and other factors are rela...
MicroRNA-204-5p hampers the malignant progression of clear cell renal cell carcinoma through GXYLT2 down-regulation
MicroRNA-204-5p hampers the malignant progression of clear cell renal cell carcinoma through GXYLT2 down-regulation
Introduction: At present, the mortality rate of clear cell renal cell carcinoma (ccRCC) remains high. The development of b...
The proportion of memory CD8+ T cell predict infection event in patients with peritoneal dialysis
The proportion of memory CD8+ T cell predict infection event in patients with peritoneal dialysis
Abstract Background: The immune senescence marked by inflation of memory T cell is established in end-stage renal disease ...
Relationship between proton pump inhibitors and adverse effects in hemodialysis patients: a systematic review and meta-analysis
Relationship between proton pump inhibitors and adverse effects in hemodialysis patients: a systematic review and meta-analysis
Background:Currently, the interaction between proton pump inhibitors (PPI) and their effects on hemodialysis (HD) patients...
Impact of Salt Intake and RAAS blockade on lung SARS CoV-2 Host Factors
Impact of Salt Intake and RAAS blockade on lung SARS CoV-2 Host Factors
Introduction: The angiotensin-converting enzyme 2 (ACE2) as well as the transmembrane protease serine type 2 (TMPRSS2) hav...
Gitelman’s and Bartter’s syndromes: from genetics to the molecular basis of hypertension and more
Gitelman’s and Bartter’s syndromes: from genetics to the molecular basis of hypertension and more
Background: Gitelman’s and Bartter’s syndromes (GS/BS) are rare genetic tubulopathies characterized by electrolyte imbalan...
Pterostilbene, a resveratrol derivative, improves ectopic lipid deposition in the kidneys of mice induced by a high-fat diet
Pterostilbene, a resveratrol derivative, improves ectopic lipid deposition in the kidneys of mice induced by a high-fat diet
Background: Diabetic kidney disease is a major cause of global end-stage renal diseases. Ectopic lipid deposition in the r...
Identification of hub gene and transcription factor related to chronic allograft nephropathy based on WGCNA analysis
Identification of hub gene and transcription factor related to chronic allograft nephropathy based on WGCNA analysis
Abstract Introduction Kidney transplantation has surpassed dialysis as the optimal therapy for end-stage kidney disease (E...
How the availability of anti-C5a agents could change the management of ANCA-associated Vasculitis
How the availability of anti-C5a agents could change the management of ANCA-associated Vasculitis
Background: Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a cluster of potentially life-threa...