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Neoadjuvant Chemotherapy Versus Primary Debulking Surgery in FIGO Stage III and IV Epithelial Ovarian, Tubal or Peritoneal Cancer: A Systematic Review and Meta-Analysis
Neoadjuvant Chemotherapy Versus Primary Debulking Surgery in FIGO Stage III and IV Epithelial Ovarian, Tubal or Peritoneal Cancer: A Systematic Review and Meta-Analysis
Objective: To investigate whether neoadjuvant chemotherapy (NACT) confers superior outcomes compared to primary debulking ...
NF-κB Signaling in Tumor Pathways Focusing on Breast and Ovarian Cancer
NF-κB Signaling in Tumor Pathways Focusing on Breast and Ovarian Cancer
Immune disorders and cancer share a common pathway involving NF-κb signaling. Through involvement with GM-CSF, NF-κB can c...
Deciphering Driver of Nasopharyngeal Cancer Development
Deciphering Driver of Nasopharyngeal Cancer Development
A great deal of progress has been made on understanding nasopharyngeal cancer in recent decades. Genomic, transcriptomic, ...
Cancer—A Pragmatic Switch to Combat Metabolic Syndrome?
Cancer—A Pragmatic Switch to Combat Metabolic Syndrome?
Both cancer and metabolic disease have become the prevalent health risks in modern societies worldwide. Cancer is a comple...
Rosetta Stone for Cancer Cure: Comparison of the Anticancer Capacity of Endogenous Estrogens, Synthetic Estrogens and Antiestrogens
Rosetta Stone for Cancer Cure: Comparison of the Anticancer Capacity of Endogenous Estrogens, Synthetic Estrogens and Antiestrogens
This work presents the history of the recognition of principal regulatory capacities of estrogen hormones having been mist...
Changing Colorectal Cancer Trends in Asians: Epidemiology and Risk Factors
Changing Colorectal Cancer Trends in Asians: Epidemiology and Risk Factors
Once an infrequent disease in parts of Asia, the rate of colorectal cancer in recent decades appears to be steadily increa...
Challenges and Opportunities Associated With Drug Delivery for the Treatment of Solid Tumors
Challenges and Opportunities Associated With Drug Delivery for the Treatment of Solid Tumors
In this review, we discuss the effectiveness of drug delivery system based on metal nanoparticles, and also, describe the ...
Timing of Early Salvage Therapy for Patients With Biochemical Relapse of Prostate Carcinoma
Timing of Early Salvage Therapy for Patients With Biochemical Relapse of Prostate Carcinoma
Between 25% and 33% of patients after radical prostatectomy experience a relapse of the disease. The risk of relapse incre...
Rationale for the Use of Homologous Recombination Proficient Molecular Profile as a Biomarker for Therapeutic Targeting in Ovarian Cancer
Rationale for the Use of Homologous Recombination Proficient Molecular Profile as a Biomarker for Therapeutic Targeting in Ovarian Cancer
IntroductionTherapeutic options for advanced-stage ovarian cancer patients are limited in those subjects with homologous r...
Research Trends in Molecular Biological Studies on Oral Squamous Cell Carcinoma: A Bibliometric Analysis
Research Trends in Molecular Biological Studies on Oral Squamous Cell Carcinoma: A Bibliometric Analysis
Background: Since the discovery of PCR and ELISA, in vitro research in the realm of molecular biology pertaining to oral s...
Advances in Research, Diagnosis, and Treatment of Neuroendocrine Cervical Carcinoma: A Review
Advances in Research, Diagnosis, and Treatment of Neuroendocrine Cervical Carcinoma: A Review
Neuroendocrine neoplasms (NENs) were classified separately in the 5th edition (2020) of the World Health Organization (WHO...
Genetic Polymorphisms Involved in Bladder Cancer: A Global Review
Genetic Polymorphisms Involved in Bladder Cancer: A Global Review
Bladder cancer (BC) has been associated with genetic susceptibility. Single peptide polymorphisms (SNPs) can modulate BC s...
Immune Checkpoint Inhibitors and Their Cardiovascular Adverse Effects
Immune Checkpoint Inhibitors and Their Cardiovascular Adverse Effects
Immune checkpoint inhibitors (ICIs) have reshaped and have become a well-established treatment modality for multiple advan...
Challenges of FGFR2 Testing in Gastric Cancer
Challenges of FGFR2 Testing in Gastric Cancer
IntroductionIn spite of a decrease in the incidence of gastric cancer, the mortality rate from this tumor remains quite hi...
Multimodal Management of Colorectal Liver Metastases: State of the Art
Multimodal Management of Colorectal Liver Metastases: State of the Art
Liver is the most common site of colorectal cancer (CRC) metastases. Treatment of CRC liver metastases (CRLM) includes dif...
Transplantable Murine Tumors in the Studies of Peptide Antitumor Vaccines
Transplantable Murine Tumors in the Studies of Peptide Antitumor Vaccines
Numerous studies have shown that antitumor vaccines based on synthetic peptides are safe and can induce both CD8+ and CD4+...
Palliative Care for Cancer Patients in Asia: Challenges and Countermeasures
Palliative Care for Cancer Patients in Asia: Challenges and Countermeasures
With the increasing incidence of cancer worldwide, palliative care has become an effective intervention to relieve cancer ...
Metastatic Pancreatic Cancer: Where Are We?
Metastatic Pancreatic Cancer: Where Are We?
Pancreatic cancer is one of the most lethal neoplasms worldwide; it is aggressive in nature and has a poor prognosis. The ...
Management of Neuroendocrine Breast Carcinoma (NEBC): Review of Literature
Management of Neuroendocrine Breast Carcinoma (NEBC): Review of Literature
Extra pulmonary high-grade poorly differentiated neuroendocrine carcinomas (EP-NECs) are rare tumors that usually arise in...
Human papillomavirus prevalence in oral and oropharyngeal squamous cell carcinoma in South America
Ferlay J, Ervik M, Lam F, et al. Global Cancer Observatory: Cancer Today. Int Agency Res Cancer 2020...
Residential radon exposure and cancer
World Health Organization. Radon and health. 2021. Available from: https://www.who.int/news-room/fac...
Molecular drivers of oral cavity squamous cell carcinoma in non-smoking and non-drinking patients: what do we know so far?
Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence a...
Ultrasounds in cancer therapy: A summary of their use and unexplored potential
Lento PH, Primack S. Advances and utility of diagnostic ultrasound in musculoskeletal medicine. Curr...
Glucose transporters as markers of diagnosis and prognosis in cancer diseases
Saier MH Jr. Families of transmembrane sugar transport proteins. Mol Microbiol 2000;35:699-710. ...
The effect of imatinib and nilotinib on blood calcium and blood potassium levels in chronic myeloid leukemia patients: a literature review
Bispo JAB, Pinheiro PS, Kobetz EK. Epidemiology and etiology of leukemia and lymphoma. Perspect Med ...
Immunotherapy using PD‑1/PDL-1 inhibitors in metastatic triple‑negative breast cancer: a systematic review
Bertucci F., Finetti P., Simeone I., Hendrickx W., Wang E., Marincola F.M., Viens P., Mamessier E., ...
Immunotherapy using PD‑1/PDL-1 inhibitors in triple‑negative breast cancer: a systematic review
Bertucci F., Finetti P., Simeone I., Hendrickx W., Wang E., Marincola F.M., Viens P., Mamessier E., ...
The effect of imatinib and nilotinib on blood calcium and blood potassium levels in chronic myeloid leukemia patient: a literature review
Bispo JAB, Pinheiro PS, Kobetz EK. Epidemiology and etiology of leukemia and lymphoma. Perspect Med ...
Programmed death ligand-1 protein expression difference in basal like and non-basal like triple negative breast cancer and its association with disease free survival and overall survival: A systematic review
Perou CM, Sørile T, Eisen MB, et al. Molecular portraits of human breast tumors. Nature 2000;406:747...
Donafenib in Chinese patients with advanced hepatocellular carcinoma (HCC): Really a new standard of care, or should we change paradigm for drug development in HCC?
Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence a...
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