SCI时时刷

search
+
Current views on etiology, diagnosis, epidemiology and gene therapy of maturity onset diabetes in the young
IntroductionMaturity-onset diabetes of the young (MODY), a historical term for some forms of monogenic diabetes, is a grou...
Biological mechanisms of dopamine D2-like receptor agonist therapy in diabetes
A recent case report by Sahota and colleagues has provided new insights into treatment of dysglycemia via dopamine (DA) re...
High-intensity training on CREB activation for improving brain health: a narrative review of possible molecular talks
1 IntroductionMaintaining brain health and cognitive function impacts the quality of life as individuals age. In recent ye...
Value of triglyceride glucose-body mass index in predicting nonalcoholic fatty liver disease in individuals with type 2 diabetes mellitus
IntroductionAccording to the 2021 Diabetes Atlas report by the International Diabetes Federation (IDF) (1), China has the ...
The atherogenic index of plasma is associated with an increased risk of diabetes in non-obese adults: a cohort study
IntroductionDiabetes mellitus (DM) is a significant global public health issue, characterized by chronic metabolic dysregu...
Determining the status of small dense low-density lipoprotein cholesterol level in women undergoing menopausal transition
1 IntroductionThe life expectancy at birth in mainland China was 81.0 years for women in 2019 and is expected to rise stea...
Impact of sperm DNA fragmentation index on assisted reproductive outcomes: a retrospective analysis
IntroductionIt is well known that male factors contribute to infertility at approximately the same rate as female factors ...
Glucagon-like peptide-1 receptor agonists and type 1 diabetes: a potential game changer?
1 IntroductionSince its introduction in 1921, insulin has changed the management and prognosis of patients with type 1 dia...
Immortalized Schwann cell lines as useful tools for pathogenesis-based therapeutic approaches to diabetic peripheral neuropathy
1 IntroductionAs glial cells in the peripheral nervous system (PNS), Schwann cells are responsible for providing trophic s...
Analyzing the impact of glycemic metabolic status on cardiovascular mortality and all-cause mortality related to the estimated glucose disposal rate: a nationwide cohort study
BackgroundCardiovascular diseases (CVD) are a major health concern worldwide (1). According to the Global Burden of Diseas...
Interpreting IGF-1 in children treated with recombinant growth hormone: challenges during early puberty
1 IntroductionIn children with growth hormone (GH) deficiency, response to recombinant GH treatment is highly variable due...
Impact of dapagliflozin on metabolic phenotype, hormone levels, and fertility in female mice after prolonged high-fat diet
IntroductionHigh-fat diet (HFD) intake is a major risk factor for obesity, which in turn leads to an increased incidence o...
Case report: Long-term efficacy and safety of semaglutide in the treatment of syndromic obesity in Prader Willi syndrome - case series and literature review
1 IntroductionPrader-Willi syndrome (PWS) is a rare genetic disorder characterized by impaired hypothalamic development an...
Metabolic dysfunction-associated fatty liver disease and risk of nephrolithiasis: a sizeable cross-sectional study
1 IntroductionNephrolithiasis is a common disease of the urinary system. It is characterized by the formation of mineral c...
Non-parathyroid hypercalcemia in a patient with new-onset hyperthyroidism and silicone-induced granulomas: case report
IntroductionHypercalcemia is a relatively common clinical condition, affecting approximately 1% of worldwide population (1...
Development and validation of machine learning models for MASLD: based on multiple potential screening indicators
BackgroundMultifaceted factors play a crucial role in the prevention and treatment of metabolic dysfunction-associated ste...
NOD1: a metabolic modulator
1 IntroductionNucleotide-binding oligomerization domain-1 (NOD1), a member of the NOD-like receptor family, is an intracel...
Molecular insights into the interplay between type 2 diabetes mellitus and osteoporosis: implications for endocrine health
Background: Type 2 diabetes mellitus (T2DM) and osteoporosis are prevalent, interconnected chronic diseases that significa...
Causal relationship between 412 gut microbiota, 1,400 blood metabolites, and diabetic nephropathy: a randomized Mendelian study
1 IntroductionDiabetic nephropathy (DN) refers to kidney damage caused by diabetes and is one of the most common microvasc...
Therapeutic targeting of obesity-induced neuroinflammation and neurodegeneration
1 IntroductionObesity is a metabolic syndrome characterized by lipid accumulation and is commonly associated with low-grad...
Impact of pubertal timing on growth progression and final height in subjects affected by RASopathies
IntroductionRASopathies (Noonan syndrome (NS) and related disorders) are multisystemic conditions caused by mutations affe...
Diminished ovarian reserve is associated to euploidy rate: a single center study
1 IntroductionIt is widely known that there is a strong correlation between female age and the chances of spontaneous conc...
A clinical decision model for failed adrenal vein sampling in primary aldosteronism
IntroductionPrimary aldosteronism (PA) is a common cause of secondary hypertension and is associated with a higher risk of...
A systematic review on gut microbiota in type 2 diabetes mellitus
1 IntroductionThe human body hosts a vast population of microorganisms, including archaebacteria, viruses, fungi and eubac...
Comparison of Individualized Rescue Luteal Phase Support Strategies with Vaginal and Combined Vaginal & Subcutaneous Progesterone Administration in Artificial Frozen-Thawed Blastocyst Embryo Transfer Cycles Based on Serum Progesterone levels
IntroductionFrozen embryo transfer (FET) has been a widely used technique in assisted reproductive technology (ART) practi...
Serum-derived small extracellular vesicles as biomarkers for predicting pregnancy and delivery on assisted reproductive technology in patients with endometriosis
1 IntroductionInfertility has received widespread attention owing to its rapid increase among generations in worldwide. As...
Lipid metabolism indicators provide tools for the diagnosis of non-alcoholic fatty liver disease: results of a nationwide survey
IntroductionNon-alcoholic fatty liver disease (NAFLD) is a chronic liver condition marked by excessive lipid accumulation ...
Genetically predicted brain cortical structure mediates the causality between insulin resistance and cognitive impairment
1 IntroductionEpidemiological studies indicate that over 55 million people were affected by dementia in 2019. The World He...
Comparison of clinicopathological characteristics and prognosis between primary squamous cell carcinoma of the thyroid and squamous cell carcinoma combined with papillary thyroid carcinoma
1 IntroductionPrimary squamous cell carcinoma of the thyroid (PSCCT) is a highly aggressive malignant tumor, accounting fo...
The association between primary frozen shoulder and serum lipids may be overestimated: evidence based on retrospective observational studies and Mendelian randomization
1 IntroductionFor Primary frozen shoulder, also known as “adhesive capsulitis of the shoulder”, is a common shoulder disor...
阅读更多
format_indent_increase