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The value of G-CSF in women experienced at least one implantation failure: a systematic review and meta-analysis
The value of G-CSF in women experienced at least one implantation failure: a systematic review and meta-analysis
ObjectiveDespite the developments of in vitro fertilization (IVF) protocols, implantation failure remains a challenging pr...
Genetic and inflammatory factors underlying gestational diabetes mellitus: a review
Genetic and inflammatory factors underlying gestational diabetes mellitus: a review
Gestational diabetes mellitus (GDM) poses a significant global health concern, impacting both maternal and fetal well-bein...
Decreasing lifetime prevalence of diabetes-related foot ulcers in Norway: repeated cross-sectional population-based surveys from the HUNT study (1995-2019)
Decreasing lifetime prevalence of diabetes-related foot ulcers in Norway: repeated cross-sectional population-based surveys from the HUNT study (1995-2019)
Background and aimsDiabetes-related foot ulcers (DFU) are a persistent healthcare challenge, impacting both patients and h...
Editorial: The role of thyroid hormones in vertebrate development, volume II
Editorial: The role of thyroid hormones in vertebrate development, volume II
The thyroid hormone is an important signaling molecule system involved in vertebrate development, acting at the embryonic ...
Feasibility and safety of modified en-bloc resection in endoscopic thyroid surgery via bilateral areolar approach – long-term institutional analysis ten years after surgery
Feasibility and safety of modified en-bloc resection in endoscopic thyroid surgery via bilateral areolar approach – long-term institutional analysis ten years after surgery
PurposeThis study aimed to introduce a new modified en-bloc resection method and evaluate its feasibility and safety in en...
Mechanisms of mitochondrial dysfunction in ovarian aging and potential interventions
Mechanisms of mitochondrial dysfunction in ovarian aging and potential interventions
Mitochondria plays an essential role in regulating cellular metabolic homeostasis, proliferation/differentiation, and cell...
Editorial: Menopause: mood disorders and obesity
Editorial: Menopause: mood disorders and obesity
This Research Topic aimed to provide an overview of the relationship between mood disorders and obesity in the context of ...
Diabetic peripheral neuropathy: age-stratified glycemic control
Diabetic peripheral neuropathy: age-stratified glycemic control
BackgroundWe explore the effect of suboptimal glycemic control on the incidence of diabetic peripheral neuropathy (DPN) in...
Elevated sortilin expression discriminates functional from non-functional neuroendocrine tumors and enables therapeutic targeting
Elevated sortilin expression discriminates functional from non-functional neuroendocrine tumors and enables therapeutic targeting
A subset of neuroendocrine tumors (NETs) can cause an excessive secretion of hormones, neuropeptides, and biogenic amines ...
Epidemiological patterns of chronic kidney disease attributed to type 2 diabetes from 1990-2019
Epidemiological patterns of chronic kidney disease attributed to type 2 diabetes from 1990-2019
BackgroundThis study investigates the burden of chronic kidney disease attributed to type 2 diabetes (CKD-T2D) across diff...
Protective effect of higher free thyroxine levels within the reference range on biliary tract cancer risk: a multivariable mendelian randomization and mediation analysis
Protective effect of higher free thyroxine levels within the reference range on biliary tract cancer risk: a multivariable mendelian randomization and mediation analysis
BackgroundHepatobiliary cancer (HBC), including hepatocellular carcinoma (HCC) and biliary tract cancer (BTC), is currentl...
The association between lymphocyte-to-monocyte ratio and all-cause mortality in obese hypertensive patients with diabetes and without diabetes: results from the cohort study of NHANES 2001–2018
The association between lymphocyte-to-monocyte ratio and all-cause mortality in obese hypertensive patients with diabetes and without diabetes: results from the cohort study of NHANES 2001–2018
ObjectiveObesity, hypertension and diabetes are high prevalent that are often associated with poor outcomes. They have bec...
Intraoperative radiofrequency ablation for unresectable abdominal paraganglioma: a case report
Intraoperative radiofrequency ablation for unresectable abdominal paraganglioma: a case report
For pheochromocytoma and paraganglioma (PPGL), the efficacy of percutaneous ablative therapies in achieving control of met...
Impact of the diagnosis of metabolic dysfunction-associated fatty liver disease and non-alcoholic fatty liver disease in patients undergoing liver transplantation for hepatocellular carcinoma
Impact of the diagnosis of metabolic dysfunction-associated fatty liver disease and non-alcoholic fatty liver disease in patients undergoing liver transplantation for hepatocellular carcinoma
PurposeWhether the diagnosis of non-alcoholic fatty liver disease or metabolic dysfunction-associated fatty disease has a ...
Accuracy of continuous glucose monitoring during exercise-related hypoglycemia in individuals with type 1 diabetes
Accuracy of continuous glucose monitoring during exercise-related hypoglycemia in individuals with type 1 diabetes
BackgroundHypoglycemia is common in individuals with type 1 diabetes, especially during exercise. We investigated the accu...
Challenges and opportunities in obesity: the role of adipocytes during tissue fibrosis
Challenges and opportunities in obesity: the role of adipocytes during tissue fibrosis
Obesity is a chronic disease that affects the energy balance of the whole body. In addition to increasing fat mass, tissue...
The clinical value of iodine-125 seed implantation in the treatment of iodine-refractory differentiated thyroid carcinoma
The clinical value of iodine-125 seed implantation in the treatment of iodine-refractory differentiated thyroid carcinoma
ObjectiveTo explore the clinical benefits of 125I seed implantation for iodine-refractory differentiated thyroid cancer (R...
Analysis of the uterine artery pulsatility index on the day of endometrial transformation and pregnancy outcomes of patients undergoing frozen–thawed embryo transfer
Analysis of the uterine artery pulsatility index on the day of endometrial transformation and pregnancy outcomes of patients undergoing frozen–thawed embryo transfer
ObjectiveThe objective was to analyze the impact of the uterine artery pulsatility index (PI) on pregnancy outcomes by mea...
Impact of serum leptin and adiponectin levels on brain infarcts in patients with mild cognitive impairment and Alzheimer’s disease: a longitudinal analysis
Impact of serum leptin and adiponectin levels on brain infarcts in patients with mild cognitive impairment and Alzheimer’s disease: a longitudinal analysis
IntroductionThe adipokines leptin and adiponectin have been associated with atherosclerosis and the risk of cerebral infar...
Causal associations of male infertility with stroke: a two-sample Mendelian randomization study
Causal associations of male infertility with stroke: a two-sample Mendelian randomization study
BackgroundStroke is a devastating global health issue, with high mortality and disability rates. The increasing prevalence...
Research hot spots and trends in endocrine-related adverse events caused by immune checkpoint inhibitors: a bibliometric analysis and visualization research
Research hot spots and trends in endocrine-related adverse events caused by immune checkpoint inhibitors: a bibliometric analysis and visualization research
BackgroundIn recent years, with the widespread use of immune checkpoint inhibitors (ICIs) in cancer treatment, the toxicit...
Non-alcoholic fatty liver disease and coexisting depression, anxiety and/or stress in adults: a systematic review and meta-analysis
Non-alcoholic fatty liver disease and coexisting depression, anxiety and/or stress in adults: a systematic review and meta-analysis
BackgroundNon-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease, affecting 25-30% of the general pop...
Phosphaturic mesenchymal tumor-induced bilateral osteomalacia femoral neck fractures: a case report
Phosphaturic mesenchymal tumor-induced bilateral osteomalacia femoral neck fractures: a case report
Phosphaturic mesenchymal tumors (PMT) are rare and distinctive tumors that typically result in paraneoplastic syndrome kno...
Non-invasive biomarkers for sperm retrieval in non-obstructive patients: a comprehensive review
Non-invasive biomarkers for sperm retrieval in non-obstructive patients: a comprehensive review
Recent advancements in reproductive medicine have guided novel strategies for addressing male infertility, particularly in...
High progesterone levels on the day after HCG injection has no effect on clinical pregnancy outcomes in in vitro fertilization-embryo transfer
High progesterone levels on the day after HCG injection has no effect on clinical pregnancy outcomes in in vitro fertilization-embryo transfer
BackgroundThis study investigates the potential impact of high progesterone (P) level on the day following human chorionic...
The Yin and Yang of the oxytocin and stress systems: opposites, yet interdependent and intertwined determinants of lifelong health trajectories
The Yin and Yang of the oxytocin and stress systems: opposites, yet interdependent and intertwined determinants of lifelong health trajectories
During parturition and the immediate post-partum period there are two opposite, yet interdependent and intertwined systems...
Gonadal dysfunction in a man with Noonan syndrome from the LZTR1 variant: case report and review of literature
Gonadal dysfunction in a man with Noonan syndrome from the LZTR1 variant: case report and review of literature
Noonan syndrome (NS) is a genetic disorder characterized by multiple congenital defects caused by mutations in the RAS/mit...
Arthrospira platensis enriched with Cr(III), Mg(II), and Mn(II) ions improves insulin sensitivity and reduces systemic inflammation in equine metabolic affected horses
Arthrospira platensis enriched with Cr(III), Mg(II), and Mn(II) ions improves insulin sensitivity and reduces systemic inflammation in equine metabolic affected horses
Equine metabolic syndrome (EMS) is a critical endocrine condition in horses, characterized by hyperinsulinemia, hyperlipid...
Transcriptomic analysis reveals sex-specific patterns in the hippocampus in Alzheimer’s disease
Transcriptomic analysis reveals sex-specific patterns in the hippocampus in Alzheimer’s disease
BackgroundThe hippocampus, vital for memory and learning, is among the first brain regions affected in Alzheimer’s Disease...
Advancements in culture technology of adipose-derived stromal/stem cells: implications for diabetes and its complications
Advancements in culture technology of adipose-derived stromal/stem cells: implications for diabetes and its complications
Stem cell-based therapies exhibit considerable promise in the treatment of diabetes and its complications. Extensive resea...
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