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Harnessing the power of nutritional antioxidants against adrenal hormone imbalance-associated oxidative stress
Harnessing the power of nutritional antioxidants against adrenal hormone imbalance-associated oxidative stress
Oxidative stress, resulting from dysregulation in the secretion of adrenal hormones, represents a major concern in human h...
The obesogenic side of Genistein
The obesogenic side of Genistein
Genistein (GN) has been highly recommended for its medicinal properties like anticancer, antidiabetic, antihyperlipidemic,...
Editorial: Insights in cellular endocrinology: 2022
Editorial: Insights in cellular endocrinology: 2022
The first review article is related to metabolic diseases and focuses on the importance of the maintenance of the pancreat...
Brain and serum metabolomic studies reveal therapeutic effects of san hua decoction in rats with ischemic stroke
Brain and serum metabolomic studies reveal therapeutic effects of san hua decoction in rats with ischemic stroke
San Hua Decoction (SHD) is a traditional four-herbal formula that has long been used to treat stroke. Our study used a tra...
PPARG dysregulation as a potential molecular target in adrenal Cushing's syndrome
PPARG dysregulation as a potential molecular target in adrenal Cushing's syndrome
BackgroundWe performed a transcriptomic analysis of adrenal signaling pathways in various forms of endogenous Cushing’s sy...
Association between serum uric acid level and bone mineral density in men more than 50 years of age
Association between serum uric acid level and bone mineral density in men more than 50 years of age
BackgroundThe results of previous studies on the association between serum uric acid levels and bone mineral density and t...
Association of lipoprotein(a) with left ventricular hypertrophy assessed by electrocardiogram in adults: a large cross-sectional study
Association of lipoprotein(a) with left ventricular hypertrophy assessed by electrocardiogram in adults: a large cross-sectional study
Background and aimsIncreasing evidence supports a causal relationship between lipoprotein(a) [Lp(a)] and atherosclerotic c...
Editorial: Current and future trends in gestational diabetes diagnosis, care and neonatal outcomes
Editorial: Current and future trends in gestational diabetes diagnosis, care and neonatal outcomes
Gestational diabetes mellitus (GDM) is defined in the World Health Organization guidelines as glucose intolerance or hyper...
Editorial: Adipokines and hormone-dependent cancers
Editorial: Adipokines and hormone-dependent cancers
Over the last two decades it has been progressively recognised the functional role of adipose tissue as an active and immu...
Prevalence and characteristics of thelarche variant
Prevalence and characteristics of thelarche variant
IntroductionGirls with early thelarche may show an intermediate clinical picture between isolated premature thelarche (PT)...
Total bilirubin and bilirubin-to-triglycerides ratio predict changes in glycated hemoglobin in healthy children
Total bilirubin and bilirubin-to-triglycerides ratio predict changes in glycated hemoglobin in healthy children
ObjectiveBilirubin and triglycerides can regulate insulin secretion and glucose uptake. The aim of our study is to analyze...
Causal effects of circulating lipids and lipid-lowering drugs on the risk of urinary stones: a Mendelian randomization study
Causal effects of circulating lipids and lipid-lowering drugs on the risk of urinary stones: a Mendelian randomization study
BackgroundPrevious studies have yielded conflicting findings regarding the association between circulating lipids and lipi...
Multiple myeloma following bone metastasis of renal cell carcinoma: a case report
Multiple myeloma following bone metastasis of renal cell carcinoma: a case report
BackgroundThe clinical manifestations of multiple myeloma (MM) and bone metastatic tumor are both systemic bone pain, whic...
Single-cell profiling reveals transcriptomic signatures of vascular endothelial cells in non-healing diabetic foot ulcers
Single-cell profiling reveals transcriptomic signatures of vascular endothelial cells in non-healing diabetic foot ulcers
BackgroundThe treatment of diabetic foot ulcers (DFUs) poses a challenging medical problem that has long plagued individua...
Ghrelin misbalance affects mice embryo implantation and pregnancy success by uterine immune dysregulation and nitrosative stress
Ghrelin misbalance affects mice embryo implantation and pregnancy success by uterine immune dysregulation and nitrosative stress
IntroductionIn a previous study we found that ghrelin (Ghrl) misbalance during the peri-implantation period significantly ...
Diabetes status and cognitive function in middle-aged and older adults in the Canadian longitudinal study on aging
Diabetes status and cognitive function in middle-aged and older adults in the Canadian longitudinal study on aging
ObjectivesDiabetes is recognized as a significant risk factor for cognitive impairment. However, this association has not ...
A bibliometric analysis of PCSK9 inhibitors from 2007 to 2022
A bibliometric analysis of PCSK9 inhibitors from 2007 to 2022
BackgroundSince the approval of the proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies for market...
Family history of malignant or benign thyroid tumors: implications for surgical procedure management and disease-free survival
Family history of malignant or benign thyroid tumors: implications for surgical procedure management and disease-free survival
BackgroundCurrent guidelines lack a standardized management for patients with family history of thyroid carcinoma (fTC),pa...
Undiagnosed diabetic retinopathy in Northeast China: prevalence and determinants
Undiagnosed diabetic retinopathy in Northeast China: prevalence and determinants
ObjectiveTo report the prevalence and contributing factors of undiagnosed diabetic retinopathy (DR) in a population from N...
Association between urinary sodium and circulating lipid levels: a Mendelian randomization study
Association between urinary sodium and circulating lipid levels: a Mendelian randomization study
BackgroundUrinary sodium was indicated to be associated with dyslipidemia, but inconsistent conclusions for this associati...
Using feature optimization and LightGBM algorithm to predict the clinical pregnancy outcomes after in vitro fertilization
Using feature optimization and LightGBM algorithm to predict the clinical pregnancy outcomes after in vitro fertilization
BackgroundAccording to a recent report by the WHO, approximately 17.5\% (about one-sixth) of the global adult population i...
Thyroid dysfunction and risk of cutaneous malignant melanoma: a bidirectional two-sample Mendelian randomization study
Thyroid dysfunction and risk of cutaneous malignant melanoma: a bidirectional two-sample Mendelian randomization study
BackgroundEpidemiologic and observational data have found a risk association between thyroid dysfunction and cutaneous mal...