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Estradiol-to-follicle ratio on human chorionic gonadotropin day is a novel predictor of gestational diabetes mellitus in women receiving fresh embryo transfer
Estradiol-to-follicle ratio on human chorionic gonadotropin day is a novel predictor of gestational diabetes mellitus in women receiving fresh embryo transfer
AimsTo assess the predictive value of estradiol (E2) related parameters on the incidence of gestational diabetes mellitus ...
Evidence of apoptosis as an early event leading to cyclophosphamide-induced primordial follicle depletion in a prepubertal mouse model
Evidence of apoptosis as an early event leading to cyclophosphamide-induced primordial follicle depletion in a prepubertal mouse model
IntroductionThe mechanisms leading to ovarian primordial follicle depletion following gonadotoxic chemotherapy with cyclop...
Obesity-related renal dysfunction: gender-specific influence of visceral adiposity and early impact of metabolic and bariatric surgery
Obesity-related renal dysfunction: gender-specific influence of visceral adiposity and early impact of metabolic and bariatric surgery
IntroductionRenal dysfunction is a recognized complication of obesity with an incompletely characterized pathophysiology. ...
The role of p53 in male infertility
The role of p53 in male infertility
The tumor suppressor p53 is a transcription factor involved in a variety of crucial cellular functions, including cell cyc...
Targeting AMP-activated protein kinase in sepsis
Targeting AMP-activated protein kinase in sepsis
Sepsis is a global health challenge marked by limited clinical options and high mortality rates. AMP-activated protein kin...
The associations of the triglyceride-glucose index and its combination with blood pressure on cardiovascular and all-cause mortality in hypertension: a national study
The associations of the triglyceride-glucose index and its combination with blood pressure on cardiovascular and all-cause mortality in hypertension: a national study
The triglyceride-glucose (TyG) index, a reliable surrogate biomarker of insulin resistance (IR), is highlighted recently a...
Association of dietary and circulating antioxidant vitamins with metabolic syndrome: an observational and Mendelian randomization study
Association of dietary and circulating antioxidant vitamins with metabolic syndrome: an observational and Mendelian randomization study
AimsThe objective of this study was to investigate the associations of dietary and circulating antioxidant vitamins with m...
Opportunities for digitally-enabled personalization and decision support for pediatric growth hormone therapy
Opportunities for digitally-enabled personalization and decision support for pediatric growth hormone therapy
Smart technologies and connected health are providing opportunities for improved healthcare for chronic conditions. Accept...
Current status of the prediction for radio-iodine refractory thyroid cancer: a narrative review
Current status of the prediction for radio-iodine refractory thyroid cancer: a narrative review
It is well established that patients with the most differentiated thyroid cancers have a good prognosis, whereas when the ...
Causal association between gastrointestinal diseases and coronary artery disease: a bidirectional Mendelian randomization study
Causal association between gastrointestinal diseases and coronary artery disease: a bidirectional Mendelian randomization study
BackgroundCoronary artery disease (CAD) has been a dominating reason of mortality globally due to its complexity of etiolo...
Elevated non-HDL-C to HDL-C ratio as a marker for NAFLD and liver fibrosis risk: a cross-sectional analysis
Elevated non-HDL-C to HDL-C ratio as a marker for NAFLD and liver fibrosis risk: a cross-sectional analysis
BackgroundDyslipidemia is a known independent risk factor for Nonalcoholic fatty liver disease (NAFLD). However, the relat...
Systemic treatments for radioiodine-refractory thyroid cancers
Systemic treatments for radioiodine-refractory thyroid cancers
Differentiated thyroid cancers (DTCs) constitute the primary histological subtype within thyroid cancer. Due to DTCs’ dist...
Enhanced joint pain in diabetic patients with knee osteoarthritis is associated with increased synovitis, synovial immune cell infiltration, and erythrocyte extravasation
Enhanced joint pain in diabetic patients with knee osteoarthritis is associated with increased synovitis, synovial immune cell infiltration, and erythrocyte extravasation
ObjectiveDiabetes mellitus (DM) is an important risk factor for the development of osteoarthritis (OA), increasing OA prog...
Tracing links between micronutrients and type 2 diabetes risk: the singular role of selenium
Tracing links between micronutrients and type 2 diabetes risk: the singular role of selenium
BackgroundType 2 diabetes (T2D) is a growing global health concern. While micronutrients are crucial for physiological fun...
Exploration of physical activity, sedentary behavior and insulin level among short sleepers
Exploration of physical activity, sedentary behavior and insulin level among short sleepers
BackgroundSufficient physical activity and sleep duration are essential for overall health. While one-third of the US popu...
Editorial: Molecular mechanisms underlying exercise-alleviated sarcopenic obesity
Sarcopenic obesity (SO), characterized by the concurrent decline in muscle mass and 9 function alongside an increase in bo...
Investigating factors influencing overweight and obesity among adult households in Ethiopia: a multilevel ordered analysis of 2016 EDHS data
Investigating factors influencing overweight and obesity among adult households in Ethiopia: a multilevel ordered analysis of 2016 EDHS data
BackgroundIn both high- and low-income countries, including Ethiopia, overweight and obesity have emerged as public health...
Acupoint catgut embedding: a potential intervention strategy for obesity-related precocious puberty
Acupoint catgut embedding: a potential intervention strategy for obesity-related precocious puberty
IntroductionObesity-related precocious puberty is induced by obesity, and acupoint catgut embedding (ACE) therapy is known...
Effects of mesenchymal stromal cells and human recombinant Nerve Growth Factor delivered by bioengineered human corneal lenticule on an innovative model of diabetic retinopathy
Effects of mesenchymal stromal cells and human recombinant Nerve Growth Factor delivered by bioengineered human corneal lenticule on an innovative model of diabetic retinopathy
IntroductionDiabetic retinopathy (DR) is a microvascular complication of diabetes in which neurodegeneration has been rece...
Multi-omics approach to reveal follicular metabolic changes and their effects on oocyte competence in PCOS patients
Multi-omics approach to reveal follicular metabolic changes and their effects on oocyte competence in PCOS patients
BackgroundPolycystic ovary syndrome (PCOS) is a common heterogeneous disorder linked with endocrine and metabolic disturba...
Serum iron status is associated with all-cause mortality in metabolic dysfunction-associated steatotic liver disease: a prospective, observational study
Serum iron status is associated with all-cause mortality in metabolic dysfunction-associated steatotic liver disease: a prospective, observational study
IntroductionMetabolic dysfunction-associated steatotic liver disease (MASLD) is the leading chronic liver disease worldwid...
Multifactorial analysis of risk factors for foot ulcers in patients with neurovascular complications of diabetes
Multifactorial analysis of risk factors for foot ulcers in patients with neurovascular complications of diabetes
BackgroundDiabetic foot ulcers (DFU) are a major complication associated with significant morbidity and mortality. While n...
Mitochondrial haplogroup R offers protection against obesity in Kuwaiti and Qatari populations
Mitochondrial haplogroup R offers protection against obesity in Kuwaiti and Qatari populations
BackgroundThe Kuwaiti and Qatari populations have a high prevalence of obesity, a major risk factor for various metabolic ...
Risk of bone fracture by using dipeptidyl peptidase-4 inhibitors, glucagon-like peptide-1 receptor agonists, or sodium-glucose cotransporter-2 inhibitors in patients with type 2 diabetes mellitus: a network meta-analysis of population-based cohort studies
Risk of bone fracture by using dipeptidyl peptidase-4 inhibitors, glucagon-like peptide-1 receptor agonists, or sodium-glucose cotransporter-2 inhibitors in patients with type 2 diabetes mellitus: a network meta-analysis of population-based cohort studies
BackgroundType 2 diabetes mellitus (T2DM) is linked to a heightened likelihood of experiencing fractures. It is crucial to...
A mobile health application use among diabetes mellitus patients: a systematic review and meta-analysis
A mobile health application use among diabetes mellitus patients: a systematic review and meta-analysis
BackgroundMobile health technologies are increasingly acknowledged as a cost-effective and convenient means of delivering ...
Unveiling new chapters in medullary thyroid carcinoma therapy: advances in molecular genetics and targeted treatment strategies
Unveiling new chapters in medullary thyroid carcinoma therapy: advances in molecular genetics and targeted treatment strategies
Medullary Thyroid Carcinoma (MTC), a neuroendocrine malignancy that arises from the calcitonin-secreting parafollicular C-...
Potential genetic association between coffee/caffeine consumption and erectile dysfunction: a Mendelian randomization study and meta-analysis
Potential genetic association between coffee/caffeine consumption and erectile dysfunction: a Mendelian randomization study and meta-analysis
BackgroundCoffee is a widely consumed beverage with potential benefits for various chronic diseases. Its effect on reducin...
Association between cardiometabolic index and kidney stone from NHANES: a population-based study
Association between cardiometabolic index and kidney stone from NHANES: a population-based study
PurposeThe Cardiometabolic Index (CMI) is a novel marker of visceral obesity and dyslipidemia. Our study aimed to explore ...
Rate of testicular histology failure in predicting successful testicular sperm extraction
Rate of testicular histology failure in predicting successful testicular sperm extraction
BackgroundThe management of Non-Obstructive (NOA) Azoospermia or Obstructive Azoospermia (OA) patients relies on testicula...
Standardizing CRISPR-Cas13 knockdown technique to investigate the role of cdh2 gene in pituitary development through growth hormone expression and transcription factors
Standardizing CRISPR-Cas13 knockdown technique to investigate the role of cdh2 gene in pituitary development through growth hormone expression and transcription factors
IntroductionCongenital hypopituitarism (CH) is characterized by the deficiency of pituitary hormones. Among CH patients, 8...
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