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Metabolically healthy across body mass index categories in relation to serum Klotho levels: a population-based study
IntroductionIn 1997, Kuro-o et al. (1) discovered that a defect in Klotho gene expression in mice results in a range of he...
Ultrasonography reference values for the calcaneus in children and adolescents living at high altitude in Peru
IntroductionBone health is defined as bone resistance to fracture, determined by the assessment of bone mineral reserve, e...
Construction of a nomogram for predicting the risk of all-cause mortality in patients with diabetic retinopathy
1 IntroductionDiabetic retinopathy (DR) is a prevalent and severe microvascular complication among individuals with diabet...
Infections and antibiotic use in early childhood have limited importance in developing manifest type 1 diabetes – The ABIS cohort study
IntroductionThe incidence of type 1 diabetes has increased greatly over the past 40-50 years (1), with a peak in global in...
The triglyceride–glucose index is a promising predictor for the risk of cardiovascular disease in the diabetic population aged ≥60 years in the United States: a retrospective cohort study from NHANES (2007-2016)
BackgroundCardiovascular disease (CVD) is regarded as one of the most seriously burdened health problems globally, and the...
Association of systemic immune inflammation index with depression among adult type 2 diabetic patients in a tertiary hospital, Ethiopia, 2022
IntroductionType 2 Diabetes Mellitus (T2DM) is a widespread and complex metabolic disorder characterized by insulin resist...
Outcomes of transsphenoidal surgery for pituitary adenomas in Spain: a retrospective multicenter study
1 IntroductionTranssphenoidal resection is the primary treatment approach for pituitary adenomas (PA) and other tumors nea...
Deciphering the association between the Life’s Essential 8 and infertility: insights into depression, inflammation, and metabolic mediation
1 IntroductionInfertility, characterized by the inability to conceive after at least 12 months of unprotected intercourse ...
Prognostic performance of examined lymph nodes, lymph node ratio, and positive lymph nodes in gastric cancer: a competing risk model study
1 IntroductionGastric cancer (GC) is the fifth most diagnosed cancer and the fourth leading cause of cancer-related mortal...
Association between visceral adiposity index and all-cause and cardiovascular mortality in the non-elderly adults
The visceral adiposity index (VAI) reflects changes in visceral adipose function and is also linked to cardiometabolic ris...
Thyroid nodule with cytological outcome of indeterminate lesion with low risk of malignancy found to be parathyroid adenoma. A case report and minireview of literature
1 IntroductionPrimary hyperparathyroidism (PHPT) is the third most common endocrine disorder, caused by excess parathyroid...
Global burden of chronic kidney disease due to diabetes mellitus, 1990-2021, and projections to 2050
1 IntroductionChronic kidney disease (CKD) is defined as abnormalities of kidney structure or function, present for greate...
Retraction: Mendelian randomization based on immune cells in diabetic nephropathy
Please find the retraction statement below:Zhou Y, Zhang H, Yan H, Huang C and Liu Y (2024) Mendelian randomization based ...
Commentary: Association between life’s essential 8 and testosterone deficiency in US men: findings from national health and nutrition examination survey (NHANES) 2011–2016
IntroductionWe read with the article by Mei et al. entitled “Association between life’s essential 8 and testosterone defic...
Ultrasound speckle tracking imaging measurement of endocardial longitudinal strain for evaluation of prognostic value of “new quadruple” therapy in patients with chronic heart failure
1 IntroductionHeart failure poses a serious threat to human health. The number of heart failure patients worldwide is risi...
Five-year evaluation of bone health in liver transplant patients: developing a risk score for predicting bone fragility progression beyond the first year
IntroductionLiver transplantation has been an accepted treatment for end-stage liver disease for over 40 years. Advancemen...
Circulating branched-chain amino acids and the risk of major adverse cardiovascular events in the UK biobank
1 IntroductionBranched-chain Amino Acids (BCAAs) — namely isoleucine, leucine, and valine — are essential amino acids that...
EndoGene database: reported genetic variants for 5,926 Russian patients diagnosed with endocrine disorders
1 IntroductionEndocrine diseases, including diabetes, thyroid dysfunction, and other hormonal imbalances, contribute signi...
Causal inference study of plasma proteins and blood metabolites mediating the effect of obesity-related indicators on osteoporosis
1 IntroductionOsteoporosis is a systemic skeletal degenerative disease characterized by a reduction in bone mass and stren...
Metformin-mediated intestinal AMPK activation ameliorates PCOS through gut microbiota modulation and metabolic pathways
1 IntroductionPolycystic Ovary Syndrome (PCOS) affects 10%-13% of women of reproductive age and is a prevalent endocrine d...
Effect of sex, pubertal stage, body mass index, oral contraceptive use, and C-reactive protein on vitamin D binding protein reference values
1 IntroductionBesides albumin, vitamin D binding protein (DBP), also known as GC-globulin, binds to all vitamin D metaboli...
Analysis of mutations in mitochondrial transfer RNA genes and the maternal inheritance of polycystic ovary syndrome
1 IntroductionPolycystic ovary syndrome (PCOS) is the most common endocrine disease affecting up to 15% of reproductive-ag...
Large copy number variants are an important cause of congenital hyperinsulinism that should be screened for during routine testing
IntroductionCongenital Hyperinsulinism (HI) is the most common cause of persistent hypoglycemia in infants and children. I...
Editorial: Endocrine aspects of Noonan syndrome and related syndromes, volume II
Pediatric endocrinologists are familiar with Noonan syndrome (NS) as the disorder represents one of the most common condit...
Editorial: Recent advances in endometriosis: from Bench to clinical application
Patients have heterogeneous, non-specific symptoms making definite diagnosis difficult without explorative laparoscopic su...
Preliminary quantitative analysis of renal sinus fat dysfunction in T2DM patients using MRI fat fraction and R2* mapping
1 IntroductionIn recent years, the prevalence of type 2 diabetes mellitus (T2DM) has reached an alarming level. In 2021, a...
Comparison of incidence trends of early-onset and late-onset type 2 diabetes in the Asia-Pacific region, 1990-2021: a join point regression analysis based on the global burden of disease study 2021
1 IntroductionType 2 diabetes presents a dual challenge: a high prevalence burden in an aging society and an accelerating ...
Ultrasonic radiomics in predicting pathologic type for thyroid cancer: a preliminary study using radiomics features for predicting medullary thyroid carcinoma
1 IntroductionThyroid cancer has been reported to account for the 9th highest incidence of all malignant tumors worldwide ...
Understanding the link between ALDH2 genotypes and diabetes
IntroductionAsians show increased susceptibility to metabolic disorders, particularly diabetes, compared to European popul...
Shared diagnostic biomarkers and underlying mechanisms between endometriosis and recurrent implantation failure
IntroductionAs a complex and enigmatic gynecological disease, endometriosis (EMs) brings dysmenorrhea, chronic pelvic pain...
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