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Hypothesis: evidence that the PRS gene products of Saccharomyces cerevisiae support both PRPP synthesis and maintenance of cell wall integrity
Hypothesis: evidence that the PRS gene products of Saccharomyces cerevisiae support both PRPP synthesis and maintenance of cell wall integrity
The gene products of PRS1-PRS5 in Saccharomyces cerevisiae are responsible for the production of PRPP (5-phospho-D-ribosyl...
Nonsense-mediated mRNA decay of metal-binding activator MAC1 is dependent on copper levels and 3′-UTR length in Saccharomyces cerevisiae
Nonsense-mediated mRNA decay of metal-binding activator MAC1 is dependent on copper levels and 3′-UTR length in Saccharomyces cerevisiae
The nonsense-mediated mRNA decay (NMD) pathway was initially identified as a surveillance pathway that degrades mRNAs cont...
Editorial evolution: welcoming our new editors-in-chief
Editorial evolution: welcoming our new editors-in-chief
Current Genetics has published significant research on how microbes work for nearly h...
GATA family transcription factors in alga Chlamydomonas reinhardtii
GATA family transcription factors in alga Chlamydomonas reinhardtii
GATA family transcription factors (GATA-TFs) are metalloproteins that regulate many metabolic pathways. These conserved pr...
Functional insights of three RING-finger peroxins in the life cycle of the insect pathogenic fungus Beauveria bassiana
Functional insights of three RING-finger peroxins in the life cycle of the insect pathogenic fungus Beauveria bassiana
Peroxisomes play important roles in fungal physiological processes. The RING-finger complex consists of peroxins Pex2, Pex...
Expression of human BRCA2 in Saccharomyces cerevisiae complements the loss of RAD52 in double-strand break repair
Expression of human BRCA2 in Saccharomyces cerevisiae complements the loss of RAD52 in double-strand break repair
BRCA2 is a tumor-suppressor gene that is normally expressed in the breast and ovarian tissue of mammals. The BRCA2 protein...
Tips for efficiently maintaining pET expression plasmids
Tips for efficiently maintaining pET expression plasmids
pET expression plasmids are widely used for producing recombinant proteins in Escherichia coli. Selection and maintenance ...
Ino2, activator of yeast phospholipid biosynthetic genes, interacts with basal transcription factors TFIIA and Bdf1
Ino2, activator of yeast phospholipid biosynthetic genes, interacts with basal transcription factors TFIIA and Bdf1
Binding of general transcription factors TFIID and TFIIA to basal promoters is rate-limiting for transcriptional initiatio...
Comparative transcriptome analysis to unveil genes affecting the host cuticle destruction in Metarhizium rileyi
Comparative transcriptome analysis to unveil genes affecting the host cuticle destruction in Metarhizium rileyi
Insect pathogenic fungi, also known as entomopathogenic fungi, are one of the largest insect pathogenic microorganism comm...
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Eukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigene...
Yeast of Eden: microbial resistance to glyphosate from a yeast perspective
Yeast of Eden: microbial resistance to glyphosate from a yeast perspective
First marketed as RoundUp, glyphosate is history’s most popular herbicide because of its low acute toxicity to metaz...
Insights from metagenome-assembled genomes on the genetic stability and safety of over-the-counter probiotic products
Insights from metagenome-assembled genomes on the genetic stability and safety of over-the-counter probiotic products
The demand for and acceptance of probiotics is determined by their quality and safety. Illumina NGS sequencing and analyti...
Amyloids and prions in the light of evolution
Amyloids and prions in the light of evolution
Functional amyloids have been identified in a wide variety of organisms including bacteria, fungi, plants, and vertebrates...
The antifungal effect induced by itraconazole in Candida parapsilosis largely depends on the oxidative stress generated at the mitochondria
The antifungal effect induced by itraconazole in Candida parapsilosis largely depends on the oxidative stress generated at the mitochondria
In Candida parapsilosis, homozygous disruption of the two genes encoding trehalase activity increased the susceptibility t...
The N-terminal disordered region of ChsB regulates its efficient transport to the hyphal apical surface in Aspergillus nidulans
The N-terminal disordered region of ChsB regulates its efficient transport to the hyphal apical surface in Aspergillus nidulans
In fungi, the cell wall plays a crucial role in morphogenesis and response to stress from the external environment. Chitin...
Tfs1, transcription elongation factor TFIIS, has an impact on chromosome segregation affected by pka1 deletion in Schizosaccharomyces pombe
Tfs1, transcription elongation factor TFIIS, has an impact on chromosome segregation affected by pka1 deletion in Schizosaccharomyces pombe
The cAMP-dependent protein kinase (PKA) pathway in Schizosaccharomyces pombe plays an important role in microtubule organi...
Application of nanotags and nanobodies for live cell single-molecule imaging of the Z-ring in Escherichia coli
Application of nanotags and nanobodies for live cell single-molecule imaging of the Z-ring in Escherichia coli
Understanding where proteins are localized in a bacterial cell is essential for understanding their function and regulatio...
Diverse and dynamic forms of gene regulation by the S. cerevisiae histone methyltransferase Set1
Diverse and dynamic forms of gene regulation by the S. cerevisiae histone methyltransferase Set1
Gene transcription is an essential and highly regulated process. In eukaryotic cells, the structural organization of nucle...
Morphogenic plasticity: the pathogenic attribute of Candida albicans
Morphogenic plasticity: the pathogenic attribute of Candida albicans
Candida albicans is a commensal organism of the human gastrointestinal tract and a prevalent opportunistic pathogen. It ex...
Mitochondria in Cryptococcus: an update of mitochondrial transcriptional regulation in Cryptococcus
Mitochondria in Cryptococcus: an update of mitochondrial transcriptional regulation in Cryptococcus
Encapsulated Cryptococcus species are responsible for approximately 15% of AIDS-related mortality. Numerous intriguing inv...
Novel determinants of cell size homeostasis in the opportunistic yeast Candida albicans
Novel determinants of cell size homeostasis in the opportunistic yeast Candida albicans
The basis for commitment to cell division in late G1 phase, called Start in yeast, is a critical but still poorly understo...
Horizontal transfer of tRNA genes to mitochondrial plasmids facilitates gene loss from fungal mitochondrial DNA
Horizontal transfer of tRNA genes to mitochondrial plasmids facilitates gene loss from fungal mitochondrial DNA
Fungal and plant mitochondria are known to exchange DNA with retroviral plasmids. Transfer of plasmid DNA to the organella...
VdERG2 was involved in ergosterol biosynthesis, nutritional differentiation and virulence of Verticillium dahliae
VdERG2 was involved in ergosterol biosynthesis, nutritional differentiation and virulence of Verticillium dahliae
The ergosterol biosynthesis pathway plays an important role in model pathogenic bacteria Saccharomyces cerevisiae, but lit...