SCI时时刷

search
+
Environmental and neurodevelopmental contributors to youth mental illness
Environmental and neurodevelopmental contributors to youth mental illness
While a myriad of factors likely contribute to the development of mental illness in young people, the social environment (...
Is treatment-resistant schizophrenia a neuroimmune condition? Meta-analytic evidence from magnetic resonance spectroscopy
Is treatment-resistant schizophrenia a neuroimmune condition? Meta-analytic evidence from magnetic resonance spectroscopy
Although the advent of next-generation antipsychotics has proven invaluable in treating schizophrenia (SZ), up to 33% of i...
Biomarker development for menstrual cycle affective change: the need for greater temporal, mechanistic, and phenotypic specificity
Biomarker development for menstrual cycle affective change: the need for greater temporal, mechanistic, and phenotypic specificity
Approximately 6% of ovulating individuals experience the debilitating affective symptoms of Premenstrual Dysphoric Disorde...
Transcranial photobiomodulation: an emerging therapeutic method to enhance brain bioenergetics
Transcranial photobiomodulation: an emerging therapeutic method to enhance brain bioenergetics
Competing interests In the last 10 years, D.V.I. has served as a consultant for ...
Brain-based graph-theoretical predictive modeling: a novel approach to prospectively map psychiatric symptoms
Brain-based graph-theoretical predictive modeling: a novel approach to prospectively map psychiatric symptoms
Competing interests Over the past 3 years, DAP has received consulting fees from...
Oxytocin treatment rescues irritability-like behavior in Cc2d1a conditional knockout mice
Oxytocin treatment rescues irritability-like behavior in Cc2d1a conditional knockout mice
Irritability, a state of excessive reactivity to negative emotional stimuli, is common in individuals with autism spectrum...
Pump the brakes: identifying neurobiological targets to enhance inhibitory control in drug addiction
Pump the brakes: identifying neurobiological targets to enhance inhibitory control in drug addiction
Impairments in inhibitory control, an essential neuropsychological function for stopping unwanted behaviors, are core to d...
Virtual reality exposure therapy advances and potential for clinical and experimental use
Competing interests Dr. Barbara Rothbaum has received Research/Grants from Wound...
Rewiring the brain: Inflammation’s impact on glutamate and neural networks in depression
Rewiring the brain: Inflammation’s impact on glutamate and neural networks in depression
Haroon E, Miller AH, Sanacora G. Inflammation, Glutamate, and Glia: A trio of trouble in mood disorders. Neuropsychopharma...
Acute, chronic and conditioned effects of intranasal oxytocin in the mu-opioid receptor knockout mouse model of autism: Social context matters
Acute, chronic and conditioned effects of intranasal oxytocin in the mu-opioid receptor knockout mouse model of autism: Social context matters
Autism Spectrum Disorders (ASD) are neurodevelopmental disorders whose diagnosis relies on deficient social interaction an...
Effects of psychedelic, DOI, on nucleus accumbens dopamine signaling to predictable rewards and cues in rats
Effects of psychedelic, DOI, on nucleus accumbens dopamine signaling to predictable rewards and cues in rats
Psychedelics produce lasting therapeutic responses in neuropsychiatric diseases suggesting they may disrupt entrenched ass...
Identification of novel genetic loci and candidate genes for progressive ethanol consumption in diversity outbred mice
Identification of novel genetic loci and candidate genes for progressive ethanol consumption in diversity outbred mice
Mouse behavioral genetic mapping studies can identify genomic intervals modulating complex traits under well-controlled en...
Breakthroughs and challenges for generating brain network-based biomarkers of treatment response in depression
Breakthroughs and challenges for generating brain network-based biomarkers of treatment response in depression
Treatment outcomes widely vary for individuals diagnosed with major depressive disorder, implicating a need for deeper und...
Distinct synaptic mechanisms drive the behavioral response to acute stress and rapid correction by ketamine
Distinct synaptic mechanisms drive the behavioral response to acute stress and rapid correction by ketamine
Prevailing hypotheses on the mechanisms of antidepressant action posit that antidepressants directly counteract deficienci...
Interaction of perceived social support and childhood maltreatment on limbic responsivity towards negative emotional stimuli in healthy individuals
Interaction of perceived social support and childhood maltreatment on limbic responsivity towards negative emotional stimuli in healthy individuals
Childhood maltreatment (CM) is associated with increased limbic activity, while social support is linked to decreased limb...
Advancement in human neuroimaging based on proximity ligation assay in brain disease
Advancement in human neuroimaging based on proximity ligation assay in brain disease
This work was supported by grants Hjärnfonden (F02019-0296), Karolinska Institutet Research Foundation (2022-02245), EMERG...
In Memoriam: Dr. James B. Appel
In Memoriam: Dr. James B. Appel
Authors and AffiliationsWilliam Rand Kenan Professor Emeritus, Department of Psychology & Neuroscience, University of ...
Applications of functional neurotransmitter release imaging with genetically encoded sensors in psychiatric research
Applications of functional neurotransmitter release imaging with genetically encoded sensors in psychiatric research
Psychiatric research encompasses diverse methodologies to understand the complex interplay between neurochemistry and beha...
Ketamine reduces the neural distinction between self- and other-produced affective touch: a randomized double-blind placebo-controlled study
Ketamine reduces the neural distinction between self- and other-produced affective touch: a randomized double-blind placebo-controlled study
A coherent sense of self is crucial for social functioning and mental health. The N-methyl-D-aspartate antagonist ketamine...
VTA glutamatergic projections to the nucleus accumbens suppress psychostimulant-seeking behavior
VTA glutamatergic projections to the nucleus accumbens suppress psychostimulant-seeking behavior
Converging evidence indicates that both dopamine and glutamate neurotransmission within the nucleus accumbens (NAc) play a...
NIMH perspectives on future directions in neuroimaging for mental health
NIMH’s mission is to transform the understanding and treatment of mental illnesses through basic and clinical resear...
Ketamine induced synaptic plasticity operates independently of long-term potentiation
Ketamine induced synaptic plasticity operates independently of long-term potentiation
Synaptic plasticity occurs via multiple mechanisms to regulate synaptic efficacy. Homeostatic and Hebbian plasticity are t...
Validation of a non-food or water motivated effort-based foraging task as a measure of motivational state in male mice
Validation of a non-food or water motivated effort-based foraging task as a measure of motivational state in male mice
Disorders of motivation such as apathy syndrome are highly prevalent across neurological disorders but do not yet have an ...
Racial and ethnic socioenvironmental inequity and neuroimaging in psychiatry: a brief review of the past and recommendations for the future
Racial and ethnic socioenvironmental inequity and neuroimaging in psychiatry: a brief review of the past and recommendations for the future
Neuroimaging is a major tool that holds immense translational potential for understanding psychiatric disorder phenomenolo...
Quality over quantity: powering neuroimaging samples in psychiatry
Quality over quantity: powering neuroimaging samples in psychiatry
Neuroimaging has been widely adopted in psychiatric research, with hopes that these non-invasive methods will provide impo...
A review of diffusion MRI in mood disorders: mechanisms and predictors of treatment response
A review of diffusion MRI in mood disorders: mechanisms and predictors of treatment response
By measuring the molecular diffusion of water molecules in brain tissue, diffusion MRI (dMRI) provides unique insight into...
In Memoriam: Larry J. Young, PhD
In Memoriam: Larry J. Young, PhD
The world of neuroscience and social behavior lost a titan with the passing of Larry Young, PhD, on M...
Extinction training suppresses activity of fear memory ensembles across the hippocampus and alters transcriptomes of fear-encoding cells
Extinction training suppresses activity of fear memory ensembles across the hippocampus and alters transcriptomes of fear-encoding cells
Contextual fear conditioning has been shown to activate a set of “fear ensemble” cells in the hippocampal dent...
Cracking the chicken and egg problem of schizophrenia and substance use: Genetic interplay between schizophrenia, cannabis use disorder, and tobacco smoking
The reason(s) underpinning the strong association between cannabis use disorder (CanUD) and schizophrenia remains a passio...
Genome-wide association studies of coffee intake in UK/US participants of European ancestry uncover cohort-specific genetic associations
Genome-wide association studies of coffee intake in UK/US participants of European ancestry uncover cohort-specific genetic associations
Coffee is one of the most widely consumed beverages. We performed a genome-wide association study (GWAS) of coffee intake ...
阅读更多
format_indent_increase