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LncRNA expression signature identified using genome-wide transcriptomic profiling to predict lymph node metastasis in patients with stage T1 and T2 gastric cancer
LncRNA expression signature identified using genome-wide transcriptomic profiling to predict lymph node metastasis in patients with stage T1 and T2 gastric cancer
Lymph node (LN) status is vital to evaluate the curative potential of relatively early gastric cancer (GC; T1–T2) tr...
CD45− erythroid progenitor cells promote lymph node metastasis in gastric cancer by inducing a hybrid epithelial/mesenchymal state in lymphatic endothelial cells
CD45− erythroid progenitor cells promote lymph node metastasis in gastric cancer by inducing a hybrid epithelial/mesenchymal state in lymphatic endothelial cells
Specific mechanisms of lymph node (LN) metastasis in early-stage gastric cancer (GC) have not been elucidated. The role of...
Efficacy and safety of trifluridine/tipiracil plus ramucirumab in comparison with trifluridine/tipiracil monotherapy for patients with advanced gastric cancer–single institutional experience
Efficacy and safety of trifluridine/tipiracil plus ramucirumab in comparison with trifluridine/tipiracil monotherapy for patients with advanced gastric cancer–single institutional experience
Trifluridine/tipiracil plus VEGF inhibition with ramucirumab (RAM) for advanced gastric cancer (AGC) demonstrated clinical...
Soluble PD-L1 as a diagnostic and prognostic biomarker in resectable gastric cancer patients
Soluble PD-L1 as a diagnostic and prognostic biomarker in resectable gastric cancer patients
In this study, we compared programmed death-ligand 1 (PD-L1) expression in primary tissue samples and its soluble form (sP...
Thromboembolic events in patients who received adjuvant chemotherapy for gastric cancer: a single-center retrospective study
Thromboembolic events in patients who received adjuvant chemotherapy for gastric cancer: a single-center retrospective study
Thromboembolic events (TEEs) are significant adverse events that can cause serious morbidities and mortality in cancer pat...
Multicenter phase II study of capecitabine plus oxaliplatin in older patients with advanced gastric cancer: the Tokyo Cooperative Oncology Group (TCOG) GI-1601 study
Multicenter phase II study of capecitabine plus oxaliplatin in older patients with advanced gastric cancer: the Tokyo Cooperative Oncology Group (TCOG) GI-1601 study
Capecitabine plus oxaliplatin (CapeOX) is a standard treatment option for advanced gastric cancer (AGC). We conducted a pr...
Prognostic value of post-operative serum procalcitonin in gastric adenocarcinoma patients undergoing radical gastrectomy: propensity score matching analysis of extended cohort from a prospective bi-center study
Prognostic value of post-operative serum procalcitonin in gastric adenocarcinoma patients undergoing radical gastrectomy: propensity score matching analysis of extended cohort from a prospective bi-center study
The aim of this study was to investigate the predictive value of procalcitonin (PCT) on post-operative day (POD) 3 and 5 f...
PPARδ dysregulation of CCL20/CCR6 axis promotes gastric adenocarcinoma carcinogenesis by remodeling gastric tumor microenvironment
PPARδ dysregulation of CCL20/CCR6 axis promotes gastric adenocarcinoma carcinogenesis by remodeling gastric tumor microenvironment
Peroxisome proliferator-activated receptor delta (PPARδ) promotes inflammation and carcinogenesis in many organs, but...
Numerous lesions of gastric adenocarcinoma of fundic-gland and fundic gland-mucosa type in a patient
Numerous lesions of gastric adenocarcinoma of fundic-gland and fundic gland-mucosa type in a patient
A man in his 60 s underwent upper gastrointestinal endoscopy at our hospital, which revealed a 30-mm elevated les...
Endoscopic differential diagnosis between foveolar-type gastric adenoma and gastric hyperplastic polyps in Helicobacter pylori-naïve patients
Endoscopic differential diagnosis between foveolar-type gastric adenoma and gastric hyperplastic polyps in Helicobacter pylori-naïve patients
Foveolar-type gastric adenoma (FGA) occurs in Helicobacter pylori (Hp)-naïve individuals and morphologically mimics H...
Addition of docetaxel to S-1 results in significantly superior 5-year survival outcomes in Stage III gastric cancer: a final report of the JACCRO GC-07 study
Addition of docetaxel to S-1 results in significantly superior 5-year survival outcomes in Stage III gastric cancer: a final report of the JACCRO GC-07 study
A phase III trial comparing S-1 and docetaxel with S-1 alone as postoperative chemotherapy for pathologically Stage III ga...
Down-regulation of stimulator of interferon genes (STING) expression and CD8+ T-cell infiltration depending on HER2 heterogeneity in HER2-positive gastric cancer
Down-regulation of stimulator of interferon genes (STING) expression and CD8+ T-cell infiltration depending on HER2 heterogeneity in HER2-positive gastric cancer
HER2 signaling might be involved in the regulation of immune cell activation in the tumor microenvironment (TME) of gastri...
Circulating hormones and risk of gastric cancer by subsite in three cohort studies
Circulating hormones and risk of gastric cancer by subsite in three cohort studies
Obesity has been positively associated with gastric cancer. Excess fat impacts hormones, which have been implicated in car...
Concordance of microsatellite instability and mismatch repair status in paired biopsies and surgical specimens of resectable gastroesophageal adenocarcinoma: time for a call to action
Concordance of microsatellite instability and mismatch repair status in paired biopsies and surgical specimens of resectable gastroesophageal adenocarcinoma: time for a call to action
Reliability of mismatch repair proteins and microsatellite instability assessment is essential in order to define treatmen...
Metachronous primary gastric cancer after endoscopic resection in patients with esophageal squamous cell carcinoma
Metachronous primary gastric cancer after endoscopic resection in patients with esophageal squamous cell carcinoma
This study aimed to evaluate the risk factors for developing metachronous primary Gastric Cancer (GC) after Endoscopic Res...
Long-term outcomes of a phase II study of neoadjuvant imatinib in large gastrointestinal stromal tumors of the stomach
Long-term outcomes of a phase II study of neoadjuvant imatinib in large gastrointestinal stromal tumors of the stomach
Neoadjuvant treatment is recommended for large GISTs due to their friability and risk of extensive operations; however, st...
Anthracycline chemicals with anthracyclinone structure exert antitumor effects by inhibiting angiogenesis and lymphangiogenesis in a xenografted gastric tumor model
Anthracycline chemicals with anthracyclinone structure exert antitumor effects by inhibiting angiogenesis and lymphangiogenesis in a xenografted gastric tumor model
It is vital to screen or develop alternative therapeutic drugs with higher curative characteristics and fewer side effects...
Photodynamic therapy improves the outcome of immune checkpoint inhibitors via remodelling anti-tumour immunity in patients with gastric cancer
Photodynamic therapy improves the outcome of immune checkpoint inhibitors via remodelling anti-tumour immunity in patients with gastric cancer
Photodynamic therapy (PDT) plays an immunoregulatory role in tumours. Here, we conducted a retrospective patient analysis ...
Effect of the number of cycles of docetaxel + S-1 therapy on long-term survival in adjuvant chemotherapy for stage III gastric cancer. A pooled analysis of the OGSG0604 and OGSG1002 trials
Effect of the number of cycles of docetaxel + S-1 therapy on long-term survival in adjuvant chemotherapy for stage III gastric cancer. A pooled analysis of the OGSG0604 and OGSG1002 trials
S-1 plus docetaxel (DS) therapy followed by S-1 is the standard of care in Japan in postoperative adjuvant chemotherapy fo...
Relationship between antithrombotic drugs and postoperative outcomes in patients with gastric cancer after gastrectomy: a propensity matching analysis
Relationship between antithrombotic drugs and postoperative outcomes in patients with gastric cancer after gastrectomy: a propensity matching analysis
As there is no consensus on the impact of antithrombotic drugs on post-gastrectomy outcomes in gastric cancer patients, th...
The occurrence, progression and development of four types of gastric mucosal atrophic lesions and their histopathological characteristics
The occurrence, progression and development of four types of gastric mucosal atrophic lesions and their histopathological characteristics
To investigate the occurrence and development of gastric mucosal atrophic lesions and their histopathological characterist...
Digital histopathological images of biopsy predict response to neoadjuvant chemotherapy for locally advanced gastric cancer
Digital histopathological images of biopsy predict response to neoadjuvant chemotherapy for locally advanced gastric cancer
Neoadjuvant chemotherapy (NAC) has been recognized as an effective therapeutic option for locally advanced gastric cancer ...
Gastric cancer mesenchymal stem cells via the CXCR2/HK2/PD-L1 pathway mediate immunosuppression
Gastric cancer mesenchymal stem cells via the CXCR2/HK2/PD-L1 pathway mediate immunosuppression
Anti-PD-1 immunotherapy has emerged as an important therapeutic modality in advanced gastric cancer (GC). However, drug re...
Neoadjuvant chemotherapy in older patients with gastric cancer undergoing surgery: a population-based cohort study
Neoadjuvant chemotherapy in older patients with gastric cancer undergoing surgery: a population-based cohort study
In trials evaluating perioperative chemotherapy for gastric cancer, which serve as the basis for treatment guidelines, pat...
Correction: Effect of Helicobacter pylori eradication after subtotal gastrectomy on the survival rate of patients with gastric cancer: follow-up for up to 15 years
Correction: Effect of Helicobacter pylori eradication after subtotal gastrectomy on the survival rate of patients with gastric cancer: follow-up for up to 15 years
Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South KoreaYonghoon Choi, Nayoung K...
Deep learning-based subtyping of gastric cancer histology predicts clinical outcome: a multi-institutional retrospective study
Deep learning-based subtyping of gastric cancer histology predicts clinical outcome: a multi-institutional retrospective study
The Laurén classification is widely used for Gastric Cancer (GC) histology subtyping. However, this classification is...
Combined loss of CDH1 and downstream regulatory sequences drive early-onset diffuse gastric cancer and increase penetrance of hereditary diffuse gastric cancer
Combined loss of CDH1 and downstream regulatory sequences drive early-onset diffuse gastric cancer and increase penetrance of hereditary diffuse gastric cancer
Germline CDH1 pathogenic or likely pathogenic variants cause hereditary diffuse gastric cancer (HDGC). Once a genetic caus...
Oncological impact of unexpected horizontal tumor spread in gastric cancer that requires total gastrectomy
Oncological impact of unexpected horizontal tumor spread in gastric cancer that requires total gastrectomy
Gastric cancer often exhibits discrepancies between the gross and pathological tumor boundaries, and the degree of discrep...
SPRY4 inhibits and sensitizes the primary KIT mutants in gastrointestinal stromal tumors (GISTs) to imatinib
SPRY4 inhibits and sensitizes the primary KIT mutants in gastrointestinal stromal tumors (GISTs) to imatinib
KIT is frequently mutated in gastrointestinal stromal tumors (GISTs), and the treatment of GISTs largely relies on targeti...
The methylation level of a single cancer risk marker gene reflects methylation burden in gastric mucosa
The methylation level of a single cancer risk marker gene reflects methylation burden in gastric mucosa
Gastric cancer risk can be accurately predicted by measuring the methylation level of a single marker gene in gastric muco...
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