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Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy
Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy
Integrating molecular-targeted agents into combination chemotherapy is transformative for enhancing treatment outcomes in ...
Safety and feasibility of single-incision laparoscopic distal gastrectomy in overweight and obese gastric cancer patients: a propensity score-matched analysis
Safety and feasibility of single-incision laparoscopic distal gastrectomy in overweight and obese gastric cancer patients: a propensity score-matched analysis
The technical challenges and safety concerns of single-incision laparoscopic gastrectomy for overweight and obese gastric ...
Genomic events stratifying prognosis of early gastric cancer
Genomic events stratifying prognosis of early gastric cancer
The purpose of the study was to conduct a comprehensive genomic characterization of gene alterations, microsatellite insta...
Importance of duodenal stump reinforcement to prevent stump leakage after gastrectomy: a large-scale multicenter retrospective study (KSCC DELICATE study)
Importance of duodenal stump reinforcement to prevent stump leakage after gastrectomy: a large-scale multicenter retrospective study (KSCC DELICATE study)
The significance of reinforcement of the duodenal stump with seromuscular sutures and the effectiveness of reinforced stap...
An artificial intelligence system for comprehensive pathologic outcome prediction in early gastric cancer through endoscopic image analysis (with video)
An artificial intelligence system for comprehensive pathologic outcome prediction in early gastric cancer through endoscopic image analysis (with video)
Accurate prediction of pathologic results for early gastric cancer (EGC) based on endoscopic findings is essential in deci...
Global prevalence of claudin 18 isoform 2 in tumors of patients with locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma
Global prevalence of claudin 18 isoform 2 in tumors of patients with locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma
Limited data exist for global prevalence of claudin 18 isoform 2 (CLDN18.2) positivity and association of CLDN18.2 status ...
Antibody–drug conjugates in gastric cancer: from molecular landscape to clinical strategies
Antibody–drug conjugates in gastric cancer: from molecular landscape to clinical strategies
Antibody–drug conjugates (ADCs) represent a crucial component of targeted therapies in gastric cancer, potentially a...
Gastric microbiome signature for predicting metachronous recurrence after endoscopic resection of gastric neoplasm
Gastric microbiome signature for predicting metachronous recurrence after endoscopic resection of gastric neoplasm
Changes in gastric microbiome are associated with gastric carcinogenesis. Studies on the association between gastric mucos...
A systematic review on the effectiveness of robot-assisted minimally invasive gastrectomy
A systematic review on the effectiveness of robot-assisted minimally invasive gastrectomy
Robot-assisted minimally invasive gastrectomy (RAMIG) is increasingly used as a surgical approach for gastric cancer. This...
Adding salt to food at table as an indicator of gastric cancer risk among adults: a prospective study
Adding salt to food at table as an indicator of gastric cancer risk among adults: a prospective study
While dietary salt intake has been linked with gastric cancer risk in Asian studies, findings from Western populations are...
International consensus on the management of metastatic gastric cancer: step by step in the foggy landscape
International consensus on the management of metastatic gastric cancer: step by step in the foggy landscape
Many gastric cancer patients in Western countries are diagnosed as metastatic with a median overall survival of less than ...
Adjuvant and post-recurrent treatment patterns in patients with resectable gastric cancer in japan: a retrospective database cohort study
Adjuvant and post-recurrent treatment patterns in patients with resectable gastric cancer in japan: a retrospective database cohort study
This study examined temporal shifts in adjuvant therapy patterns in Japanese patients with resectable gastric cancer (GC) ...
Feasibility of intraoperative pathologic examination for sentinel lymph nodes during sentinel node navigation surgery in early gastric cancer: results of pathologic protocol for SENORITA trial
Feasibility of intraoperative pathologic examination for sentinel lymph nodes during sentinel node navigation surgery in early gastric cancer: results of pathologic protocol for SENORITA trial
During sentinel node navigation surgery in patients with gastric cancer, intraoperative pathologic examination of sentinel...
Identification of maximal tumor size associated with negligible lymph node metastasis for endoscopic submucosal dissection of undifferentiated-type early gastric cancer
Identification of maximal tumor size associated with negligible lymph node metastasis for endoscopic submucosal dissection of undifferentiated-type early gastric cancer
When treating undifferentiated-type early gastric cancer (UD-EGC) that is limited to the mucosa (clinically T1a), endoscop...
Comparative effectiveness of sodium-glucose cotransporter-2 inhibitors for new-onset gastric cancer and gastric diseases in patients with type 2 diabetes mellitus: a population-based cohort study
Comparative effectiveness of sodium-glucose cotransporter-2 inhibitors for new-onset gastric cancer and gastric diseases in patients with type 2 diabetes mellitus: a population-based cohort study
To compare the risks of gastric cancer and other gastric diseases in patients with type-2 diabetes mellitus (T2DM) exposed...
Bemarituzumab plus mFOLFOX6 as first-line treatment in East Asian patients with FGFR2b-overexpressing locally advanced or metastatic gastric/gastroesophageal junction cancer: subgroup of FIGHT final analysis
Bemarituzumab plus mFOLFOX6 as first-line treatment in East Asian patients with FGFR2b-overexpressing locally advanced or metastatic gastric/gastroesophageal junction cancer: subgroup of FIGHT final analysis
In the FIGHT study (NCT03694522) bemarituzumab, a humanized monoclonal antibody selective for fibroblast growth factor rec...
TMEM205 induces TAM/M2 polarization to promote cisplatin resistance in gastric cancer
TMEM205 induces TAM/M2 polarization to promote cisplatin resistance in gastric cancer
Cisplatin (DDP) is a basic chemotherapy drug for gastric cancer (GC). With the increase of DDP drug concentration in clini...
CDKN2A somatic copy number amplification in normal tissues surrounding gastric carcinoma reduces cancer metastasis risk in droplet digital PCR analysis
CDKN2A somatic copy number amplification in normal tissues surrounding gastric carcinoma reduces cancer metastasis risk in droplet digital PCR analysis
The CDKN2A gene is frequently affected by somatic copy number variations (SCNVs, including deletions and amplifications [S...
Janus kinase inhibitor overcomes resistance to immune checkpoint inhibitor treatment in peritoneal dissemination of gastric cancer in C57BL/6 J mice
Janus kinase inhibitor overcomes resistance to immune checkpoint inhibitor treatment in peritoneal dissemination of gastric cancer in C57BL/6 J mice
Cancer immunotherapy aims to unleash the immune system’s potential against cancer cells, providing sustained relief ...
Impact of chemotherapy delay on long-term prognosis of laparoscopic radical surgery for locally advanced gastric cancer: a pooled analysis of four randomized controlled trials
Impact of chemotherapy delay on long-term prognosis of laparoscopic radical surgery for locally advanced gastric cancer: a pooled analysis of four randomized controlled trials
Adjuvant chemotherapy following curative surgery for locally advanced gastric cancer (AGC) significantly improves long-ter...
CTNND1 is involved in germline predisposition to early-onset gastric cancer by affecting cell-to-cell interactions
CTNND1 is involved in germline predisposition to early-onset gastric cancer by affecting cell-to-cell interactions
CDH1 and CTNNA1 remain as the main genes for hereditary gastric cancer. However, they only explain a small fraction of gas...
A machine learning model for predicting the lymph node metastasis of early gastric cancer not meeting the endoscopic curability criteria
A machine learning model for predicting the lymph node metastasis of early gastric cancer not meeting the endoscopic curability criteria
We developed a machine learning (ML) model to predict the risk of lymph node metastasis (LNM) in patients with early gastr...
YAP inhibition overcomes adaptive resistance in HER2-positive gastric cancer treated with trastuzumab via the AKT/mTOR and ERK/mTOR axis
YAP inhibition overcomes adaptive resistance in HER2-positive gastric cancer treated with trastuzumab via the AKT/mTOR and ERK/mTOR axis
Human epidermal growth factor receptor 2 (HER2)-positive gastric cancer (GC) is a heterogeneous GC subtype characterized b...
Factors associated with the efficacy of first-line nivolumab plus chemotherapy in advanced gastric cancer patients with deficient mismatch repair
Factors associated with the efficacy of first-line nivolumab plus chemotherapy in advanced gastric cancer patients with deficient mismatch repair
We aimed to investigate clinicopathologic factors leading to different clinical outcomes in patients with deficient mismat...
SMARCA4-deficient undifferentiated gastric carcinoma: a case series and literature review
SMARCA4-deficient undifferentiated gastric carcinoma: a case series and literature review
Undifferentiated gastric carcinoma, characterized by anaplastic cells lacking distinct features of cytological or architec...
Development of a reliable surgical quality assurance tool for gastrectomy in oncological trials
Development of a reliable surgical quality assurance tool for gastrectomy in oncological trials
Despite its recognized importance, there is currently no reliable tool for surgical quality assurance (SQA) of gastrectomy...
Early gastric cancer with RhoGAP fusion is linked to frequent nodal metastasis and a part of microtubular–mucocellular histology
Early gastric cancer with RhoGAP fusion is linked to frequent nodal metastasis and a part of microtubular–mucocellular histology
Gastric cancer with fusion genes involving the Rho GTPase-activating protein domain (RhoGAP-GC) is mainly included in the ...
Molecular features and prognostic factors of locally advanced microsatellite instability-high gastric cancer
Molecular features and prognostic factors of locally advanced microsatellite instability-high gastric cancer
Microsatellite instability-high (MSI-H) tumors are distinct molecular subtypes in gastric cancer. However, a few studies h...
Claudin-18 status and its correlation with HER2 and PD-L1 expression in gastric cancer with peritoneal dissemination
Claudin-18 status and its correlation with HER2 and PD-L1 expression in gastric cancer with peritoneal dissemination
Gastric cancer with peritoneal dissemination (PD) has a dismal prognosis, and current treatments have shown little efficac...
Genome-wide 5-hydroxymethylcytosines in circulating cell-free DNA as noninvasive diagnostic markers for gastric cancer
Genome-wide 5-hydroxymethylcytosines in circulating cell-free DNA as noninvasive diagnostic markers for gastric cancer
5-Hydroxymethylcytosine-enriched gene profiles and regions show tissue-specific and tumor specific. There is a potential v...
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