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The association between the triglyceride-glucose index and sarcopenia: data from the NHANES 2011–2018
The association between the triglyceride-glucose index and sarcopenia: data from the NHANES 2011–2018
The Triglyceride-glucose (TyG) index is a marker of insulin resistance, but its role in sarcopenia is controversial. The p...
Roles of lipid droplets and related proteins in metabolic diseases
Roles of lipid droplets and related proteins in metabolic diseases
Lipid droplets (LDs), which are active organelles, derive from the monolayer membrane of the endoplasmic reticulum and enc...
Associations between different triglyceride glucose index-related obesity indices and periodontitis: results from NHANES 2009–2014
Associations between different triglyceride glucose index-related obesity indices and periodontitis: results from NHANES 2009–2014
This study aimed to explore the associations between triglyceride glucose (TyG) index-related obesity indices and periodon...
Optimization of concentrations of different n-3PUFAs on antioxidant capacity in mouse hepatocytes
Optimization of concentrations of different n-3PUFAs on antioxidant capacity in mouse hepatocytes
Omega-3 polyunsaturated fatty acids (n-3 PUFAs), mainly including α-linolenic acid (ALA), eicosapentaenoic acid (EPA)...
Effects of short-chain fatty acid-butyrate supplementation on expression of circadian-clock genes, sleep quality, and inflammation in patients with active ulcerative colitis: a double-blind randomized controlled trial
Effects of short-chain fatty acid-butyrate supplementation on expression of circadian-clock genes, sleep quality, and inflammation in patients with active ulcerative colitis: a double-blind randomized controlled trial
The regulation of the circadian clock genes, which coordinate the activity of the immune system, is disturbed in inflammat...
Association between neutrophil to high-density lipoprotein cholesterol ratio (NHR) and depression symptoms among the United States adults: a cross-sectional study
Association between neutrophil to high-density lipoprotein cholesterol ratio (NHR) and depression symptoms among the United States adults: a cross-sectional study
Depression acts as a noteworthy worldwide public health challenge. Identifying accessible biomarkers is crucial for early ...
Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and sarcopenia in individuals with cancer: a cross-sectional study
Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and sarcopenia in individuals with cancer: a cross-sectional study
Cancer and sarcopenia are both closely related to lipid metabolism, but the relationship between lipid metabolism and pati...
Association between triglyceride glucose index-related indices with gallstone disease among US adults
Association between triglyceride glucose index-related indices with gallstone disease among US adults
Triglyceride glucose (TyG) index combined with obesity-related indicators [triglyceride glucose-body mass index (TyG-BMI),...
Nicotinate-curcumin improves NASH by inhibiting the AKR1B10/ACCα-mediated triglyceride synthesis
Nicotinate-curcumin improves NASH by inhibiting the AKR1B10/ACCα-mediated triglyceride synthesis
Nonalcoholic steatohepatitis (NASH) is a prevalent chronic liver condition. However, the potential therapeutic benefits an...
Deciphering the lipid–cancer nexus: comprehensive Mendelian randomization analysis of the associations between lipid profiles and digestive system cancer susceptibility
Deciphering the lipid–cancer nexus: comprehensive Mendelian randomization analysis of the associations between lipid profiles and digestive system cancer susceptibility
Digestive system cancers represent a significant global health challenge and are attributed to a combination of demographi...
Sphingolipid changes in mouse brain and plasma after mild traumatic brain injury at the acute phases
Sphingolipid changes in mouse brain and plasma after mild traumatic brain injury at the acute phases
Traumatic brain injury (TBI) causes neuroinflammation and can lead to long-term neurological dysfunction, even in cases of...
Unraveling the controversy between fasting and nonfasting lipid testing in a normal population: a systematic review and meta-analysis of 244,665 participants
Unraveling the controversy between fasting and nonfasting lipid testing in a normal population: a systematic review and meta-analysis of 244,665 participants
The final decision to fast or not fast for routine lipid profile examination in a standard, healthy population is unclear....
MiR-223 enhances lipophagy by suppressing CTSB in microglia following lysolecithin-induced demyelination in mice
MiR-223 enhances lipophagy by suppressing CTSB in microglia following lysolecithin-induced demyelination in mice
Lipid droplet (LD)-laden microglia is a key pathological hallmark of multiple sclerosis. The recent discovery of this nove...
7-MEGA™ inhibits adipogenesis in 3T3-L1 adipocytes and suppresses obesity in high-fat-diet-induced obese C57BL/6 mice
7-MEGA™ inhibits adipogenesis in 3T3-L1 adipocytes and suppresses obesity in high-fat-diet-induced obese C57BL/6 mice
Overweight, often known as obesity, is the abnormal and excessive accumulation of fat that exposes the health of a person ...
Identification of lipid-modifying drug targets for autoimmune diseases: insights from drug target mendelian randomization
Identification of lipid-modifying drug targets for autoimmune diseases: insights from drug target mendelian randomization
A growing body of evidence has highlighted the interactions of lipids metabolism and immune regulation. Nevertheless, ther...
The causal relationship and potential mediators between plasma lipids and atopic dermatitis: a bidirectional two-sample, two-step mendelian randomization
The causal relationship and potential mediators between plasma lipids and atopic dermatitis: a bidirectional two-sample, two-step mendelian randomization
Observational studies have indicated that the plasma lipid profiles of patients with atopic dermatitis show significant di...
The roles of lipids and inflammation in the association between the triglyceride-glucose index and arterial stiffness: evidence from two large population-based surveys
The roles of lipids and inflammation in the association between the triglyceride-glucose index and arterial stiffness: evidence from two large population-based surveys
The triglyceride-glucose (TyG) index is a risk marker for arterial stiffness; however, the extent to which the TyG index i...
Association between indicators of visceral lipid accumulation and infertility: a cross-sectional study based on U.S. women
Association between indicators of visceral lipid accumulation and infertility: a cross-sectional study based on U.S. women
Evidence on the association between visceral lipid accumulation and infertility remains limited and controversial. Therefo...
Association between the atherogenic index of plasma and left ventricular hypertrophy in patients with obstructive sleep apnea: a retrospective cross-sectional study
Association between the atherogenic index of plasma and left ventricular hypertrophy in patients with obstructive sleep apnea: a retrospective cross-sectional study
The atherogenic index of plasma (AIP) is a simple and reliable marker of insulin resistance and is closely associated with...
Atherogenic Index of Plasma as a Mediator in the association between Body Roundness Index and Depression: insights from NHANES 2005–2018
Atherogenic Index of Plasma as a Mediator in the association between Body Roundness Index and Depression: insights from NHANES 2005–2018
Previous studies have shown a correlation between depression and obesity, as well as between depression and the Atherogeni...
Association between body roundness index and overactive bladder: results from the NHANES 2005–2018
Association between body roundness index and overactive bladder: results from the NHANES 2005–2018
An increasing amount of research has indicated obesity greatly affects individuals with overactive bladder (OAB). However,...
LDLR c.89_92dup: a novel frameshift variation in familial hypercholesterolemia
LDLR c.89_92dup: a novel frameshift variation in familial hypercholesterolemia
Familial hypercholesterolemia (FH) is a common inherited metabolic disease that causes premature atherosclerosis, cardiova...
Non-linear association of atherogenic index of plasma with bone mineral density a cross-sectional study
Non-linear association of atherogenic index of plasma with bone mineral density a cross-sectional study
Although there has been abundant evidence of the association between dyslipidemia as a single factor and osteoporosis, the...
Association between depression and infertility risk among American women aged 18–45 years: the mediating effect of the NHHR
Association between depression and infertility risk among American women aged 18–45 years: the mediating effect of the NHHR
Depression and infertility are major medical and social problems. The non-high-density lipoprotein cholesterol to high-den...
Octanoic acid mitigates busulfan-induced blood-testis barrier damage by alleviating oxidative stress and autophagy
Octanoic acid mitigates busulfan-induced blood-testis barrier damage by alleviating oxidative stress and autophagy
The management of male infertility continues to encounter an array of challenges and constraints, necessitating an in-dept...
Assessment of leukocyte and systemic inflammation index ratios in dyslipidemia patients with dry eye disease: a retrospective case‒control study
Assessment of leukocyte and systemic inflammation index ratios in dyslipidemia patients with dry eye disease: a retrospective case‒control study
Dry eye disease (DED) is a complication of dyslipidemia (DLP) that is caused by metabolic syndrome and increased inflammat...
Correlation between remnant cholesterol and hyperuricemia in American adults
Correlation between remnant cholesterol and hyperuricemia in American adults
Remnant cholesterol (RC) is an important marker for assessing the risk of metabolic syndrome. However, the correlation bet...
Associations of lipids and lipid-modifying drug target genes with atrial fibrillation risk based on genomic data
Associations of lipids and lipid-modifying drug target genes with atrial fibrillation risk based on genomic data
The causal associations of lipids and the drug target genes with atrial fibrillation (AF) risk remain obscure. We aimed to...
Preconceptional paternal caloric restriction of high-fat diet-induced obesity in Wistar rats dysregulates the metabolism of their offspring via AMPK/SIRT1 pathway
Preconceptional paternal caloric restriction of high-fat diet-induced obesity in Wistar rats dysregulates the metabolism of their offspring via AMPK/SIRT1 pathway
Obesity is a metabolic syndrome where allelic and environmental variations together determine the susceptibility of an ind...
Association of serum fatty acid pattern with depression in U.S. adults: analysis of NHANES 2011–2012
Association of serum fatty acid pattern with depression in U.S. adults: analysis of NHANES 2011–2012
Exposure to different concentration levels of fatty acids (FAs) may have an impact on depression. However, previous studie...
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