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A comprehensive multiomics approach reveals that high levels of sphingolipids in cardiac cachexia adipose tissue are associated with inflammatory and fibrotic changes
A comprehensive multiomics approach reveals that high levels of sphingolipids in cardiac cachexia adipose tissue are associated with inflammatory and fibrotic changes
Cardiac cachexia is a deadly consequence of advanced heart failure that is characterised by the dysregulation of adipose t...
Association of cardiometabolic factors and insulin resistance surrogates with mortality in participants from the Korean Genome and Epidemiology Study
Association of cardiometabolic factors and insulin resistance surrogates with mortality in participants from the Korean Genome and Epidemiology Study
Simple biochemical and anthropometric measurements such as fasting blood glucose (FBG), triglycerides (TG), high-density l...
Evaluating the efficacy and timing of blood purification modalities in early-stage hyperlipidemic acute pancreatitis treatment
Evaluating the efficacy and timing of blood purification modalities in early-stage hyperlipidemic acute pancreatitis treatment
Hypertriglyceridemia-induced acute pancreatitis (HTG-AP) is characterized by a violent cytokine storm-driven inflammation ...
The ZJU index is associated with the risk of obstructive sleep apnea syndrome in Chinese middle-aged and older people: a cross-sectional study
The ZJU index is associated with the risk of obstructive sleep apnea syndrome in Chinese middle-aged and older people: a cross-sectional study
The ZJU index, a novel calculation that combines body mass index, triglycerides, fasting blood glucose and the ratio of al...
Associations of serum carotenoids with visceral adiposity index and lipid accumulation product: a cross-sectional study based on NHANES 2001–2006
Associations of serum carotenoids with visceral adiposity index and lipid accumulation product: a cross-sectional study based on NHANES 2001–2006
Visceral adiposity index (VAI) and lipid accumulation product (LAP) are comprehensive indicators to evaluate visceral fat ...
Correlation between dietary inflammation and mortality among hyperlipidemics
Correlation between dietary inflammation and mortality among hyperlipidemics
Although the the Dietary Inflammatory Index (DII) serves to be one of the reliable indicator for hyperlipidaemia, there is...
Exploring the hypolipidemic effects of bergenin from Saxifraga melanocentra Franch: mechanistic insights and potential for hyperlipidemia treatment
Exploring the hypolipidemic effects of bergenin from Saxifraga melanocentra Franch: mechanistic insights and potential for hyperlipidemia treatment
The goal of this study was to explore the hypolipidemic effects of bergenin extracted from Saxifraga melanocentra Franch (...
Puerarin ameliorates metabolic dysfunction-associated fatty liver disease by inhibiting ferroptosis and inflammation
Puerarin ameliorates metabolic dysfunction-associated fatty liver disease by inhibiting ferroptosis and inflammation
Metabolic dysfunction-associated fatty liver disease (MAFLD) is frequently linked to type 2 diabetes mellitus (T2DM), and ...
Ectopic and visceral fat deposition in aging, obesity, and idiopathic pulmonary fibrosis: an interconnected role
Ectopic and visceral fat deposition in aging, obesity, and idiopathic pulmonary fibrosis: an interconnected role
Idiopathic pulmonary fibrosis (IPF) is considered an age-related disease. Age-related changes, along with other factors su...
Non-alcoholic fatty liver disease risk prediction model and health management strategies for older Chinese adults: a cross-sectional study
Non-alcoholic fatty liver disease risk prediction model and health management strategies for older Chinese adults: a cross-sectional study
Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver condition that affects a quarter of the global adult p...
Role of arachidonic acid metabolism in intervertebral disc degeneration: identification of potential biomarkers and therapeutic targets via multi-omics analysis and artificial intelligence strategies
Role of arachidonic acid metabolism in intervertebral disc degeneration: identification of potential biomarkers and therapeutic targets via multi-omics analysis and artificial intelligence strategies
Intervertebral disc degeneration (IVDD) is widely recognized as the primary etiological factor underlying low back pain, o...
Altered fecal bile acid composition in active ulcerative colitis
Altered fecal bile acid composition in active ulcerative colitis
Disturbed bile acid homeostasis associated with a rise of primary and a decline of secondary bile acids is a consistent fi...
ACT001 Alleviates chronic kidney injury induced by a high-fat diet in mice through the GPR43/AMPK pathway
ACT001 Alleviates chronic kidney injury induced by a high-fat diet in mice through the GPR43/AMPK pathway
Roughly 10 -15% of global populace suffer from Chronic Kidney Disease(CKD). A major secondary disease that can progress to...
Potential impact of high-density lipoprotein cholesterol in the postoperative outcomes of chronic subdural hematoma patients: multi-institutional study in Korea
Potential impact of high-density lipoprotein cholesterol in the postoperative outcomes of chronic subdural hematoma patients: multi-institutional study in Korea
Chronic subdural hematoma (CSDH) is a common clinical situation in neurosurgical practice, but the optimal treatment optio...
The association of statin therapy and cancer: a meta-analysis
The association of statin therapy and cancer: a meta-analysis
Statins are routinely prescribed to lower cholesterol and have been demonstrated to have significant benefits in atheroscl...
Influence of renal function on the ability of TyG Index to predict all-cause mortality
Influence of renal function on the ability of TyG Index to predict all-cause mortality
The association between triglyceride–glucose (TyG) index and poor prognosis remains controversial. Whether renal fun...
The synergy of serum SFRP5 levels and the TyG index in predicting coronary artery disease and prognosing major adverse cardiovascular events
The synergy of serum SFRP5 levels and the TyG index in predicting coronary artery disease and prognosing major adverse cardiovascular events
Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that is known for its potent anti-inflammatory ...
Role of lipins in cardiovascular diseases
Role of lipins in cardiovascular diseases
Lipin family members in mammals include lipins 1, 2, and 3. Lipin family proteins play a crucial role in lipid metabolism ...
Genetically predicted triglycerides mediate the relationship between type 2 diabetes Mellitus and intervertebral disc degeneration
Genetically predicted triglycerides mediate the relationship between type 2 diabetes Mellitus and intervertebral disc degeneration
To validate the causal relationship between type 2 diabetes mellitus (T2DM) and intervertebral disc degeneration (IVDD) an...
Retraction Note: The effect of n-3/n-6 polyunsaturated fatty acids on acute reflux esophagitis in rats
Retraction Note: The effect of n-3/n-6 polyunsaturated fatty acids on acute reflux esophagitis in rats
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Circulating chemerin levels in preeclampsia: a systematic review and meta-analysis
Circulating chemerin levels in preeclampsia: a systematic review and meta-analysis
Preeclampsia (PE) is a new-onset pregnancy-specific disorder with a high prevalence that leads to over 70 000 maternal and...
Association between total cholesterol and lumbar bone density in Chinese: a study of physical examination data from 2018 to 2023
Association between total cholesterol and lumbar bone density in Chinese: a study of physical examination data from 2018 to 2023
The impact of total cholesterol (TC) on lumbar bone mineral density (BMD) is a topic of interest. However, empirical evide...
Screening and verifying the mutations in the LDLR and APOB genes in a Chinese family with familial hypercholesterolemia
Screening and verifying the mutations in the LDLR and APOB genes in a Chinese family with familial hypercholesterolemia
Familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder. The primary objective of this study was to i...
Body Mass Index is Associated with blood pressure and vital capacity in medical students
Body Mass Index is Associated with blood pressure and vital capacity in medical students
The widely reported associations between body mass index (BMI) and various chronic diseases, such as hypertension and asth...
Persistent dyslipidemia increases the longitudinal changes in telomere length
Persistent dyslipidemia increases the longitudinal changes in telomere length
Leukocyte telomere length (LTL) as a ‘biological clock’ of aging is closely related to human health, its assoc...
Sex differences in FASN protein concentrations in urinary exosomes related to serum triglycerides levels in healthy adults
Sex differences in FASN protein concentrations in urinary exosomes related to serum triglycerides levels in healthy adults
Dysregulation of lipid metabolism is the most prominent metabolic alteration observed in obesity, cancer, and cardiovascul...
The physiological and pathological properties of Mead acid, an endogenous multifunctional n-9 polyunsaturated fatty acid
The physiological and pathological properties of Mead acid, an endogenous multifunctional n-9 polyunsaturated fatty acid
Mead acid (MA, 5,8,11-eicosatrienoic acid) is an n-9 polyunsaturated fatty acid (PUFA) and a marker of essential fatty aci...
Infrared laser therapy decreases systemic oxidative stress and inflammation in hypercholesterolemic mice with periodontitis
Infrared laser therapy decreases systemic oxidative stress and inflammation in hypercholesterolemic mice with periodontitis
Near-infrared irradiation photobiomodulation (NIR-PBM) has been successfully used in periodontal treatment as an adjuvant ...
Ceramide d18:1/24:1 as a potential biomarker to differentiate obesity subtypes with unfavorable health outcomes
Ceramide d18:1/24:1 as a potential biomarker to differentiate obesity subtypes with unfavorable health outcomes
The criteria for metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUO) remain controversial. This ...
Non-HDL cholesterol and long-term follow-up outcomes in patients with metabolic syndrome
Non-HDL cholesterol and long-term follow-up outcomes in patients with metabolic syndrome
Non-high-density lipoprotein-cholesterol (non-HDL-C) has been identified as a potential biomarker for metabolic syndrome (...
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