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GRP78/BiP alleviates oxLDL-induced hepatotoxicity in familial hypercholesterolemia caused by missense variants of LDLR in a HepG2 cellular model
GRP78/BiP alleviates oxLDL-induced hepatotoxicity in familial hypercholesterolemia caused by missense variants of LDLR in a HepG2 cellular model
The accumulation of misfolded proteins, encoded by genetic variants of functional genes leads to Endoplasmic Reticulum (ER...
International practice patterns of dyslipidemia management in patients with chronic kidney disease under nephrology care: is it time to review guideline recommendations?
International practice patterns of dyslipidemia management in patients with chronic kidney disease under nephrology care: is it time to review guideline recommendations?
In contrast to guidelines related to lipid therapy in other areas, 2012 Kidney Disease Improving Global Outcomes (KDIGO) g...
Association of a high-fat diet with I-FABP as a biomarker of intestinal barrier dysfunction driven by metabolic changes in Wistar rats
Association of a high-fat diet with I-FABP as a biomarker of intestinal barrier dysfunction driven by metabolic changes in Wistar rats
The epithelial lining of the gut expresses intestinal fatty-acid binding proteins (I-FABPs), which increase in circulation...
Serum lipidomics reveals phosphatidylethanolamine and phosphatidylcholine disorders in patients with myocardial infarction and post-myocardial infarction-heart failure
Serum lipidomics reveals phosphatidylethanolamine and phosphatidylcholine disorders in patients with myocardial infarction and post-myocardial infarction-heart failure
Myocardial infarction (MI) and post-MI-heart failure (pMIHF) are a major cause of death worldwide, however, the underlying...
Association between the insulin resistance marker TyG index and subsequent adverse long-term cardiovascular events in young and middle-aged US adults based on obesity status
Association between the insulin resistance marker TyG index and subsequent adverse long-term cardiovascular events in young and middle-aged US adults based on obesity status
A lthough the triglyceride-glucose (TyG) index has been shown to closely correlate with cardiometabolic outcomes ...
Association of visceral adiposity index with asymptomatic intracranial arterial stenosis: a population-based study in Shandong, China
Association of visceral adiposity index with asymptomatic intracranial arterial stenosis: a population-based study in Shandong, China
The visceral adiposity index (VAI), as a composite indictor to evaluate visceral adipose function, has been demonstrated t...
Altered endocannabinoidome bioactive lipid levels accompany reduced DNBS-induced colonic inflammation in germ-free mice
Altered endocannabinoidome bioactive lipid levels accompany reduced DNBS-induced colonic inflammation in germ-free mice
Gut microbiota are involved in the onset and development of chronic intestinal inflammation. The recently described endoca...
Elevated postprandial triglyceride-rich lipoproteins in patients with diabetes and stable coronary artery disease correlated with early renal damage and systemic inflammation
Elevated postprandial triglyceride-rich lipoproteins in patients with diabetes and stable coronary artery disease correlated with early renal damage and systemic inflammation
Dyslipidaemia is key in the development of coronary heart disease (CHD) in patients with diabetes mellitus (DM). Accumulat...
Adjunctive therapy with lipid-lowering agents in COVID-19: a systematic review and meta-analysis of randomized controlled trials
Adjunctive therapy with lipid-lowering agents in COVID-19: a systematic review and meta-analysis of randomized controlled trials
Many commonly used drugs were evaluated as repurposed treatment options since the emergence of the COVID-19 pandemic. The ...
HDL-cholesterol concentration and its association with coronary artery calcification: a systematic review and meta-analysis
HDL-cholesterol concentration and its association with coronary artery calcification: a systematic review and meta-analysis
Coronary artery calcification (CAC) is a potential risk marker of coronary atherosclerosis that has high specificity and s...
Correction to: The association between the body roundness index and the risk of colorectal cancer: a cross-sectional study
Correction to: The association between the body roundness index and the risk of colorectal cancer: a cross-sectional study
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whic...
Referral rate, profile and degree of control of patients with familial hypercholesterolemia: data from a single lipid unit from a Mediterranean area
Referral rate, profile and degree of control of patients with familial hypercholesterolemia: data from a single lipid unit from a Mediterranean area
The challenging rigorous management of hypercholesterolemia promotes referral to specialized units. This study explored th...
Correction: Impact of Fetuin-A, Lp(a), matrix gla protein and macrophage density on calcific aortic valve disease: a clinical study
Correction: Impact of Fetuin-A, Lp(a), matrix gla protein and macrophage density on calcific aortic valve disease: a clinical study
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whic...
Comparative serum lipid and immunohematological values among adult pulmonary tuberculosis and tuberculosis lymphadenitis cases and their association with sputum bacilli load and time to culture positivity in Northwestern Ethiopia
Comparative serum lipid and immunohematological values among adult pulmonary tuberculosis and tuberculosis lymphadenitis cases and their association with sputum bacilli load and time to culture positivity in Northwestern Ethiopia
The serum lipid and immunohematological values of tuberculosis lymphadenitis (TBLN) patients is poorly documented relative...
Estimated sdLDL-C for predicting high-risk coronary plaque features in psoriasis: a prospective observational study
Estimated sdLDL-C for predicting high-risk coronary plaque features in psoriasis: a prospective observational study
Psoriasis (PSO) is a skin disorder with systemic inflammation and high coronary artery disease risk. A distinct lipid phen...
HDL and LDL have distinct, opposing effects on LPS-induced brain inflammation
HDL and LDL have distinct, opposing effects on LPS-induced brain inflammation
Endotoxemia and sepsis induce neuroinflammation and increase the risk of neurodegenerative disorders although the mechanis...
The association between the body roundness index and the risk of colorectal cancer: a cross-sectional study
The association between the body roundness index and the risk of colorectal cancer: a cross-sectional study
Colorectal cancer (CRC), has a link between obesity, especially visceral fat. The body roundness index (BRI) can more accu...
Pathogenic sphingosine 1-phosphate pathway in psoriasis: a critical review of its pathogenic significance and potential as a therapeutic target
Pathogenic sphingosine 1-phosphate pathway in psoriasis: a critical review of its pathogenic significance and potential as a therapeutic target
Sphingosine-1-phosphate (S1P) is a sphingolipid mediator that exerts a variety of biological functions, including immune, ...
In vitro, in vivo, and in silico analysis of synbiotics as preventive interventions for lipid metabolism in ethanol-induced adipose tissue injury
In vitro, in vivo, and in silico analysis of synbiotics as preventive interventions for lipid metabolism in ethanol-induced adipose tissue injury
The risk of alcoholic liver disease (ALD) is increased by excessive ethanol drinking. For the prevention of ALD, the effec...
Excessive exogenous cholesterol activating intestinal LXRα-ABCA1/G5/G8 signaling pathway can not reverse atherosclerosis in ApoE−/− mice
Excessive exogenous cholesterol activating intestinal LXRα-ABCA1/G5/G8 signaling pathway can not reverse atherosclerosis in ApoE−/− mice
The long-term excessive intake of exogenous cholesterol can lead to abnormally elevated blood lipid levels and induce card...
Leucine supplementation in maternal high-fat diet alleviated adiposity and glucose intolerance of adult mice offspring fed a postweaning high-fat diet
Leucine supplementation in maternal high-fat diet alleviated adiposity and glucose intolerance of adult mice offspring fed a postweaning high-fat diet
Combined maternal and postnatal high-fat (HF) diet intake predisposes offspring to metabolic dysregulation during adulthoo...
Distribution of serum uric acid concentration and its association with lipid profiles: a single-center retrospective study in children aged 3 to 12 years with adenoid and tonsillar hypertrophy
Distribution of serum uric acid concentration and its association with lipid profiles: a single-center retrospective study in children aged 3 to 12 years with adenoid and tonsillar hypertrophy
Presently, there is no consensus regarding the optimal serum uric acid (SUA) concentration for pediatric patients. Adenoid...
Development and validation of an online dynamic nomogram based on the atherogenic index of plasma to screen nonalcoholic fatty liver disease
Development and validation of an online dynamic nomogram based on the atherogenic index of plasma to screen nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD), a common liver disease worldwide, can be reversed early in life with lifestyle a...
Lipid metabolism reprogramming in tumor-associated macrophages and implications for therapy
Lipid metabolism reprogramming in tumor-associated macrophages and implications for therapy
The tumormicroenvironment (TME) plays a key role in tumor progression. Tumor-associated macrophages (TAMs), which are natu...
A lipid metabolism–based prognostic risk model for HBV–related hepatocellular carcinoma
A lipid metabolism–based prognostic risk model for HBV–related hepatocellular carcinoma
Up to 85% of hepatocellular carcinoma (HCC) cases in China can be attributed to infection of hepatitis B virus (HBV). Lipi...
Relationship between triglyceride-glucose index and aminotransferase among Royal Thai Army personnel 2017–2021: a serial cross-sectional study
Relationship between triglyceride-glucose index and aminotransferase among Royal Thai Army personnel 2017–2021: a serial cross-sectional study
Insulin resistance (IR) is a major pathogenesis of nonalcoholic fatty liver disease (NAFLD). The triglyceride-glucose (TyG...
Analyses of familial chylomicronemia syndrome in Pereira, Colombia 2010–2020: a cross-sectional study
Analyses of familial chylomicronemia syndrome in Pereira, Colombia 2010–2020: a cross-sectional study
Familial chylomicronemia syndrome (FCS) is a rare autosomal recessive metabolic disorder caused by mutations in genes invo...
Sex-related differences in the hypertriglyceridemic-waist phenotype in association with hyperuricemia: a longitudinal cohort study
Sex-related differences in the hypertriglyceridemic-waist phenotype in association with hyperuricemia: a longitudinal cohort study
There is limited longitudinal evidence supporting the association between the hypertriglyceridemic-waist (HTGW) phenotype ...
A pilot study of the association between maternal mid-pregnancy cholesterol and oxysterol concentrations and labor duration
A pilot study of the association between maternal mid-pregnancy cholesterol and oxysterol concentrations and labor duration
Previous animal model studies have highlighted a role for cholesterol and its oxidized derivatives (oxysterols) in uterine...
Correction: The relationship between Lipocalin-2 level and hepatic steatosis in obese patients with NAFLD after bariatric surgery
Correction: The relationship between Lipocalin-2 level and hepatic steatosis in obese patients with NAFLD after bariatric surgery
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whic...
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