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MiR-223 enhances lipophagy by suppressing CTSB in microglia following lysolecithin-induced demyelination in mice
MiR-223 enhances lipophagy by suppressing CTSB in microglia following lysolecithin-induced demyelination in mice
Lipid droplet (LD)-laden microglia is a key pathological hallmark of multiple sclerosis. The recent discovery of this nove...
7-MEGA™ inhibits adipogenesis in 3T3-L1 adipocytes and suppresses obesity in high-fat-diet-induced obese C57BL/6 mice
7-MEGA™ inhibits adipogenesis in 3T3-L1 adipocytes and suppresses obesity in high-fat-diet-induced obese C57BL/6 mice
Overweight, often known as obesity, is the abnormal and excessive accumulation of fat that exposes the health of a person ...
Identification of lipid-modifying drug targets for autoimmune diseases: insights from drug target mendelian randomization
Identification of lipid-modifying drug targets for autoimmune diseases: insights from drug target mendelian randomization
A growing body of evidence has highlighted the interactions of lipids metabolism and immune regulation. Nevertheless, ther...
The causal relationship and potential mediators between plasma lipids and atopic dermatitis: a bidirectional two-sample, two-step mendelian randomization
The causal relationship and potential mediators between plasma lipids and atopic dermatitis: a bidirectional two-sample, two-step mendelian randomization
Observational studies have indicated that the plasma lipid profiles of patients with atopic dermatitis show significant di...
The roles of lipids and inflammation in the association between the triglyceride-glucose index and arterial stiffness: evidence from two large population-based surveys
The roles of lipids and inflammation in the association between the triglyceride-glucose index and arterial stiffness: evidence from two large population-based surveys
The triglyceride-glucose (TyG) index is a risk marker for arterial stiffness; however, the extent to which the TyG index i...
Association between indicators of visceral lipid accumulation and infertility: a cross-sectional study based on U.S. women
Association between indicators of visceral lipid accumulation and infertility: a cross-sectional study based on U.S. women
Evidence on the association between visceral lipid accumulation and infertility remains limited and controversial. Therefo...
Association between the atherogenic index of plasma and left ventricular hypertrophy in patients with obstructive sleep apnea: a retrospective cross-sectional study
Association between the atherogenic index of plasma and left ventricular hypertrophy in patients with obstructive sleep apnea: a retrospective cross-sectional study
The atherogenic index of plasma (AIP) is a simple and reliable marker of insulin resistance and is closely associated with...
Atherogenic Index of Plasma as a Mediator in the association between Body Roundness Index and Depression: insights from NHANES 2005–2018
Atherogenic Index of Plasma as a Mediator in the association between Body Roundness Index and Depression: insights from NHANES 2005–2018
Previous studies have shown a correlation between depression and obesity, as well as between depression and the Atherogeni...
Association between body roundness index and overactive bladder: results from the NHANES 2005–2018
Association between body roundness index and overactive bladder: results from the NHANES 2005–2018
An increasing amount of research has indicated obesity greatly affects individuals with overactive bladder (OAB). However,...
LDLR c.89_92dup: a novel frameshift variation in familial hypercholesterolemia
LDLR c.89_92dup: a novel frameshift variation in familial hypercholesterolemia
Familial hypercholesterolemia (FH) is a common inherited metabolic disease that causes premature atherosclerosis, cardiova...
Non-linear association of atherogenic index of plasma with bone mineral density a cross-sectional study
Non-linear association of atherogenic index of plasma with bone mineral density a cross-sectional study
Although there has been abundant evidence of the association between dyslipidemia as a single factor and osteoporosis, the...
Association between depression and infertility risk among American women aged 18–45 years: the mediating effect of the NHHR
Association between depression and infertility risk among American women aged 18–45 years: the mediating effect of the NHHR
Depression and infertility are major medical and social problems. The non-high-density lipoprotein cholesterol to high-den...
Octanoic acid mitigates busulfan-induced blood-testis barrier damage by alleviating oxidative stress and autophagy
Octanoic acid mitigates busulfan-induced blood-testis barrier damage by alleviating oxidative stress and autophagy
The management of male infertility continues to encounter an array of challenges and constraints, necessitating an in-dept...
Assessment of leukocyte and systemic inflammation index ratios in dyslipidemia patients with dry eye disease: a retrospective case‒control study
Assessment of leukocyte and systemic inflammation index ratios in dyslipidemia patients with dry eye disease: a retrospective case‒control study
Dry eye disease (DED) is a complication of dyslipidemia (DLP) that is caused by metabolic syndrome and increased inflammat...
Correlation between remnant cholesterol and hyperuricemia in American adults
Correlation between remnant cholesterol and hyperuricemia in American adults
Remnant cholesterol (RC) is an important marker for assessing the risk of metabolic syndrome. However, the correlation bet...
Associations of lipids and lipid-modifying drug target genes with atrial fibrillation risk based on genomic data
Associations of lipids and lipid-modifying drug target genes with atrial fibrillation risk based on genomic data
The causal associations of lipids and the drug target genes with atrial fibrillation (AF) risk remain obscure. We aimed to...
Preconceptional paternal caloric restriction of high-fat diet-induced obesity in Wistar rats dysregulates the metabolism of their offspring via AMPK/SIRT1 pathway
Preconceptional paternal caloric restriction of high-fat diet-induced obesity in Wistar rats dysregulates the metabolism of their offspring via AMPK/SIRT1 pathway
Obesity is a metabolic syndrome where allelic and environmental variations together determine the susceptibility of an ind...
Association of serum fatty acid pattern with depression in U.S. adults: analysis of NHANES 2011–2012
Association of serum fatty acid pattern with depression in U.S. adults: analysis of NHANES 2011–2012
Exposure to different concentration levels of fatty acids (FAs) may have an impact on depression. However, previous studie...
Association between monocyte-to-high-density lipoprotein-cholesterol ratio and gallstones in U.S. adults: findings from the National Health and Nutrition Examination Survey 2017–2020
Association between monocyte-to-high-density lipoprotein-cholesterol ratio and gallstones in U.S. adults: findings from the National Health and Nutrition Examination Survey 2017–2020
Studies have indicated that monocyte-to-high-density lipoprotein cholesterol ratio (MHR) can be a reliable indicator of va...
Association of plasma high-density lipoprotein cholesterol level with risk of stress urinary incontinence in women: a retrospective study
Association of plasma high-density lipoprotein cholesterol level with risk of stress urinary incontinence in women: a retrospective study
Studies have found that high density lipoprotein cholesterol (HDL-C) levels are linked to a variety of diseases. However, ...
The residual risk of inflammation and remnant cholesterol in acute coronary syndrome patients on statin treatment undergoing percutaneous coronary intervention
The residual risk of inflammation and remnant cholesterol in acute coronary syndrome patients on statin treatment undergoing percutaneous coronary intervention
Residual risk assessment for acute coronary syndrome (ACS) patients after sufficient medical management remains challengin...
Association between maternal blood lipids and neonatal hypoglycaemia in pregnancy with gestational diabetes mellitus: a cohort study
Association between maternal blood lipids and neonatal hypoglycaemia in pregnancy with gestational diabetes mellitus: a cohort study
Gestational diabetes mellitus (GDM) prevalence is on the rise globally. Offspring of diabetic mothers face increased risk ...
The association between polyunsaturated fatty acids and periodontitis: NHANES 2011–2014 and Mendelian randomisation analysis
The association between polyunsaturated fatty acids and periodontitis: NHANES 2011–2014 and Mendelian randomisation analysis
We aimed to explore the association and potential causality between polyunsaturated fatty acids concentrations and the ris...
Association between blood lipids and diabetes mellitus in older Chinese adults aged 65 years or older: a cross-sectional analysis of residents’ electronic health records
Association between blood lipids and diabetes mellitus in older Chinese adults aged 65 years or older: a cross-sectional analysis of residents’ electronic health records
This study aimed to investigate how blood lipids are associated with diabetes among older Chinese adults. 3,268,928 older ...
Cluster analysis of clinical, angiographic, and laboratory parameters in patients with ST-segment elevation myocardial infarction
Cluster analysis of clinical, angiographic, and laboratory parameters in patients with ST-segment elevation myocardial infarction
ST-segment elevation myocardial infarction (STEMI) represents the most harmful clinical manifestation of coronary artery d...
High remnant-cholesterol levels increase the risk for end-stage renal disease: a nationwide, population-based, cohort study
High remnant-cholesterol levels increase the risk for end-stage renal disease: a nationwide, population-based, cohort study
The effect of remnant-cholesterol (remnant-C) on incident end-stage renal disease (ESRD) has not been studied longitudinal...
Association between a body shape index and cognitive impairment among us older adults from a cross-sectional survey of the NHANES 2011–2014
Association between a body shape index and cognitive impairment among us older adults from a cross-sectional survey of the NHANES 2011–2014
This study aimed to assess the relationship between A Body Shape Index (ABSI) and cognitive impairment among older adults ...
Association of blood urea nitrogen with all-cause and cardiovascular mortality in hyperlipidemia: NHANES 1999–2018
Association of blood urea nitrogen with all-cause and cardiovascular mortality in hyperlipidemia: NHANES 1999–2018
Although blood urea nitrogen (BUN) has a crucial impact on many diseases, its effect on outcomes in patients with hyperlip...
The association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and the risk of osteoporosis among U.S. adults: analysis of NHANES data
The association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and the risk of osteoporosis among U.S. adults: analysis of NHANES data
Osteoporosis and atherosclerosis frequently afflict older adults, and recent insights suggest a deeper connection between ...
Association between triglyceride glucose-waist to height ratio and coronary heart disease: a population-based study
Association between triglyceride glucose-waist to height ratio and coronary heart disease: a population-based study
The Triglyceride glucose (TyG) index-related indicators improve risk stratification by identifying individuals prone to at...
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