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Polyphenol-driven facile assembly of a nanosized acid fibroblast growth factor-containing coacervate accelerates the healing of diabetic wounds
Diabetes wounds occur in approximately 20% of diabetic patients and have a poor prognosis, high recurrence rate, and often...
A predictive model for the thermomechanical melting transition of double stranded DNA
After the pioneering experimental work in [1], mechanical molecular experiments allowed increasingly sophisticated analyse...
Injectable Decellularized Dental Pulp Matrix-Functionalized Hydrogel Microspheres for Endodontic Regeneration
When the dental pulp is infected by the bacteria of carious or traumatic origin, inflammation and tissue necrosis occur, e...
Extracellular matrix drives tumor organoids toward desmoplastic matrix deposition and mesenchymal transition
Cholangiocarcinoma (CCA) is a highly aggressive tumor which arises from the biliary duct epithelium. It is associated with...
Live Bio-nano-sonosensitizer targets malignant tumors in synergistic therapy
With the rapid development of nanotechnology, there has been growing interest in new strategies for the treatment of tumor...
Complete gene sequence and mechanical property of the fourth type of major ampullate silk protein
Spider silks are renowned for their remarkable mechanical properties. Due to combined high strength and extensibility, spi...
Dynamic changes in mechanical properties of the adult rat spinal cord after injury
Spinal cord injury (SCI), which typically causes permanent motor and sensory dysfunction, is a serious public health issue...
Development of a Photosynthetic Hydrogel as Potential Wound Dressing for the Local Delivery of Oxygen and Bioactive Molecules
Wound management and healing remain as a global clinical and scientific challenge. Therefore, the development of advanced ...
Light-triggered theranostic hydrogels for real-time imaging and on-demand photodynamic therapy of skin abscesses
Microbial infection is an escalating medical issue that has posed severe threats to human health. Wound infection is resul...
Rete ridges: morphogenesis, function, regulation, and reconstruction
Skin, the body's protective barrier, prevents water loss and shields us from numerous diseases and environmental stimuli [...
Modulation of the biophysical and biochemical properties of collagen by glycation for tissue engineering applications
Collagen type I is the most abundant extracellular matrix (ECM) protein that is responsible for conferring mechanical resi...
Semaphorin 3A Delivered by a Rapidly Polymerizing Click Hydrogel Overcomes Impaired Implant Osseointegration in a Rat Type 2 Diabetes Model
Dental implants have enabled the restoration of dentition in the growing aging population, which has resulted in improved ...
Injectable nanofiber microspheres modified with metal phenolic networks for effective osteoarthritis treatment
Osteoarthritis (OA), a chronic disease caused by the inflammation of joints, poses severe health concerns as well as disco...
Tissue engineering of decellularized pancreas scaffolds for regenerative medicine in diabetes
Various mechanical, chemical, detergent, and enzymatic techniques [23] have been used to generate decellularized pancreata...
Porous composite hydrogels with improved MSC survival for robust epithelial sealing around implants and M2 macrophage polarization
In recent years, it has been observed that the incidence of peri-implant mucositis and peri-implantitis has gradually incr...
Multi-functional plant flavonoids regulate pathological microenvironments for vascular stent surface engineering
According to the World Health Organization (WHO), cardiovascular disease has become one of the leading causes of unnatural...
Electrospun fiber-mediated delivery of neurotrophin-3 mRNA for neural tissue engineering applications
Peripheral nervous system (PNS) injury resulting from disease or trauma impacts over 20 million individuals in the United ...
Crosslinker Structure Modulates Bulk Mechanical Properties and Dictates hMSC Behavior on Hyaluronic Acid Hydrogels
Synthetic hydrogels have garnered intense interest as extracellular matrix (ECM) mimics, yet still do not fully replicate ...
Biocompatibility and biodistribution of matrix-bound nanovesicles in vitro and in vivo
Available online 22 November 2022Author links open overlay panelAbstractMatrix-bound nanovesicles (MBV) are a distinct sub...
Elasticity Imaging Using Physics-informed Neural Networks: Spatial Discovery of Elastic Modulus and Poisson's Ratio
Available online 17 November 2022Author links open overlay panelAbstractElasticity imaging is a technique that discovers t...
Surface-fill H2S-releasing Silk Fibroin Hydrogel for Brain Repair through the Repression of Neuronal Pyroptosis
Available online 17 November 2022Author links open overlay panelAbstractTraumatic brain injury (TBI) remains the major cau...
A modified biodegradable mesh ureteral stent for treating ureteral stricture disease
Ureteral stricture disease (USD) is an increasingly common urologic disease with variable causes including ureterolithiasi...