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High Throughput Automated Characterization of Enamel Microstructure using Synchrotron Tomography and Optical Flow Imaging
High Throughput Automated Characterization of Enamel Microstructure using Synchrotron Tomography and Optical Flow Imaging
Enamel, the outer protective coating of teeth, is an extremely hard mineral-based material. It exhibits distinct character...
Deciphering protein-mediated underwater adhesion in an invasive biofouling ascidian: discovery, validation, and functional mechanism of an interfacial protein
Deciphering protein-mediated underwater adhesion in an invasive biofouling ascidian: discovery, validation, and functional mechanism of an interfacial protein
Bioadhesion, the attachment of fouling organisms to submerged substrates mediated by natural biological macromolecules, is...
Local anesthetic delivery systems for the management of postoperative pain
Local anesthetic delivery systems for the management of postoperative pain
Postoperative pain (POP) caused by surgical injury to the skin, fascia, mucosa, and small nerves innervating these tissues...
Glycopeptide-based Multifunctional Nanofibrous Hydrogel that Facilitates the Healing of Diabetic Wounds Infected with Methicillin-resistant Staphylococcus aureus
Glycopeptide-based Multifunctional Nanofibrous Hydrogel that Facilitates the Healing of Diabetic Wounds Infected with Methicillin-resistant Staphylococcus aureus
Diabetes is a highly prevalent disease worldwide, and the majority of patients with diabetes experience wound ulcers durin...
Vascular stent with immobilized anti-inflammatory chemerin 15 peptides mitigates neointimal hyperplasia and accelerates vascular healing
Vascular stent with immobilized anti-inflammatory chemerin 15 peptides mitigates neointimal hyperplasia and accelerates vascular healing
Volume 179, 15 April 2024, Pages 371-384Author links open overlay panel, , , , , , , , , , , , AbstractEndovascular stenti...
Fish swim bladders as valve leaflets enhance the durability of transcatheter aortic valve replacement devices
Fish swim bladders as valve leaflets enhance the durability of transcatheter aortic valve replacement devices
Transcatheter aortic valve replacement (TAVR) has been proven to be the best course of treatment[1]. Since Cribier et al. ...
Ultra-small Janus Nanoparticle-induced Activation of Ferroptosis for Synergistic Tumor Immunotherapy
Ultra-small Janus Nanoparticle-induced Activation of Ferroptosis for Synergistic Tumor Immunotherapy
Ferroptosis is a form of regulatory cell death (RCD) evoked by lipid peroxides (LPO) [1], [2], [3], [4]. Unlike other RCD ...
In vivo Micro-computed Tomography Evaluation of Radiopaque, Polymeric Device Degradation in Normal and Inflammatory Environments
In vivo Micro-computed Tomography Evaluation of Radiopaque, Polymeric Device Degradation in Normal and Inflammatory Environments
Biomedical devices fulfill many important roles in regenerative medicine: stabilizing injured tissue, supporting repair af...
A One-Two Punch Strategy for Diabetic Wound Management Based on an Antibiotic-Hybrid Biomineralized Iron Sulfide Nanoparticle
A One-Two Punch Strategy for Diabetic Wound Management Based on an Antibiotic-Hybrid Biomineralized Iron Sulfide Nanoparticle
Diabetes constitutes a significant and escalating global concern. According to estimations by the International Diabetes F...
Decellularized Kidney Extracellular Matrix-Based Hydrogels for Renal Tissue Engineering
Decellularized Kidney Extracellular Matrix-Based Hydrogels for Renal Tissue Engineering
Available online 18 April 2024Author links open overlay panel, , , , , , AbstractKidney regeneration is hindered by the li...
Unraveling the influence of channel size and shape in 3D printed ceramic scaffolds on osteogenesis
Unraveling the influence of channel size and shape in 3D printed ceramic scaffolds on osteogenesis
Available online 18 April 2024Author links open overlay panel, , , , , , , , AbstractBone has the capacity to regenerate i...
Architecture of β-Lactoglobulin Coating Modulates Bioinspired Alginate Dialdehyde-Gelatine/Polydopamine Scaffolds for Subchondral Bone Regeneration
Architecture of β-Lactoglobulin Coating Modulates Bioinspired Alginate Dialdehyde-Gelatine/Polydopamine Scaffolds for Subchondral Bone Regeneration
In this study, we developed polydopamine (PDA)-functionalized alginate dialdehyde-gelatine (ADA-GEL) scaffolds for subchon...
Adipocyte-targeted delivery of rosiglitazone with localized photothermal therapy for the treatment of diet-induced obesity in mice
Adipocyte-targeted delivery of rosiglitazone with localized photothermal therapy for the treatment of diet-induced obesity in mice
Obesity, characterized by a body mass index (BMI) exceeding 30 kg/m2, is a significant public health concern affecting a c...
Inflammatory tissue response in human soft tissue is caused by a higher particle load near carbon fiber-reinforced PEEK compared to titanium plates
Inflammatory tissue response in human soft tissue is caused by a higher particle load near carbon fiber-reinforced PEEK compared to titanium plates
Titanium as the leading implant material in locked plating is challenged by polymers such as carbon fiber-reinforced polye...
Unveiling clinical applications of bacterial extracellular vesicles as natural nanomaterials in disease diagnosis and therapeutics
Unveiling clinical applications of bacterial extracellular vesicles as natural nanomaterials in disease diagnosis and therapeutics
Bacterial extracellular vesicles (BEVs) are naturally occurring bioactive membrane-bound nanoparticles released by both gr...
Comparative Analysis of Traction Forces in Normal and Glaucomatous Trabecular Meshwork Cells within a 3D, Active Fluid-Structure Interaction Culture Environment
Comparative Analysis of Traction Forces in Normal and Glaucomatous Trabecular Meshwork Cells within a 3D, Active Fluid-Structure Interaction Culture Environment
Primary open-angle glaucoma (POAG), a leading cause of irreversible vision loss, is primarily associated with increased in...
Lymph node targeting strategy using a hydrogel sustained-release system to load effector memory T cells improves the anti-tumor efficacy of anti-PD-1
Lymph node targeting strategy using a hydrogel sustained-release system to load effector memory T cells improves the anti-tumor efficacy of anti-PD-1
Immune checkpoint blockade (ICB) therapies targeting programmed cell death protein 1/programmed cell death ligand 1 (PD-1/...
A strong, silk protein-inspired tissue adhesive with an enhanced drug release mechanism for transdermal drug delivery
A strong, silk protein-inspired tissue adhesive with an enhanced drug release mechanism for transdermal drug delivery
Transdermal drug delivery system (TDDS) has been one of the most popular dosage forms expected to replace oral administrat...
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect
The treatment of osteoporotic bone defect remains a big clinical challenge because osteoporosis (OP) is associated with ox...
In Vivo Assessment of Dual-Function Submicron Textured Nitric Oxide Releasing Catheters in a 7-Day Rabbit Model
In Vivo Assessment of Dual-Function Submicron Textured Nitric Oxide Releasing Catheters in a 7-Day Rabbit Model
Available online 16 April 2024Author links open overlay panel, , , , , , , , , AbstractCatheter-induced thrombosis is a ma...
A Fully Biodegradable Spherical Nucleic Acid Nanoplatform for Self-codelivery of Doxorubicin and miR122 for Innate and Adaptive Immunity Activation
A Fully Biodegradable Spherical Nucleic Acid Nanoplatform for Self-codelivery of Doxorubicin and miR122 for Innate and Adaptive Immunity Activation
Polycation-mediated traditional chemo-gene therapy generally suffers from low transfection efficiency and carriers-associa...
Decellularized Extracellular Matrix enriched with GDNF Enhances Neurogenesis and Remyelination for Improved Motor Recovery after Spinal Cord Injury
Decellularized Extracellular Matrix enriched with GDNF Enhances Neurogenesis and Remyelination for Improved Motor Recovery after Spinal Cord Injury
Spinal cord injury (SCI), an intractable neurological disorder, results in neurodegeneration and motor dysfunction, leadin...
Gallium and silver-doped titanium surfaces provide enhanced osteogenesis, reduce bone resorption and prevent bacterial infection in co-culture
Gallium and silver-doped titanium surfaces provide enhanced osteogenesis, reduce bone resorption and prevent bacterial infection in co-culture
Available online 14 April 2024Author links open overlay panel, , , , , , , ABSTRACTBacterial infection remains a significa...
Viscoelastic hydrogels regulate adipose-derived mesenchymal stem cells for nucleus pulposus regeneration
Viscoelastic hydrogels regulate adipose-derived mesenchymal stem cells for nucleus pulposus regeneration
Low back pain is a leading cause of disability worldwide, often attributed to intervertebral disc (IVD) degeneration with ...
Multimodal phototherapy agents target lipid droplets for near-infrared imaging-guided type I photodynamic/photothermal therapy
Multimodal phototherapy agents target lipid droplets for near-infrared imaging-guided type I photodynamic/photothermal therapy
Phototherapy includes photodynamic therapy (PDT) and photothermal therapy (PTT). Compared with surgical resection, chemoth...
Protein Adsorption on Blood-Contacting Surfaces: A Thermodynamic Perspective to Guide the Design of Antithrombogenic Polymer Coatings
Protein Adsorption on Blood-Contacting Surfaces: A Thermodynamic Perspective to Guide the Design of Antithrombogenic Polymer Coatings
Available online 12 April 2024Author links open overlay panel, , , , AbstractBlood-contacting medical devices often succum...
Anisotropic power-law viscoelasticity of living cells is dominated by cytoskeletal network structure
Anisotropic power-law viscoelasticity of living cells is dominated by cytoskeletal network structure
Exploring the viscoelastic behaviors of living cells is of utmost importance to comprehend the roles of mechanical forces ...
Microenvironment-regulated dual-hydrophilic coatings for glaucoma valve surface engineering
Microenvironment-regulated dual-hydrophilic coatings for glaucoma valve surface engineering
Glaucoma is a multifaceted optic nerve disease with characteristic nerve damage and visual field defects [1]. Glaucoma is ...
Regulatory Insights into Nanomedicine and Gene Vaccine Innovation: Safety Assessment, Challenges, and Regulatory Perspectives
Regulatory Insights into Nanomedicine and Gene Vaccine Innovation: Safety Assessment, Challenges, and Regulatory Perspectives
KeywordsNanomedicinesGene vaccinesRegulatory issuesSafety assessmentIntellectual property rightsEthical considerationsList...
Biomimicking Covalent Organic Frameworks Nanocomposite Coating for Integrated Enhanced Anticorrosion and Antifouling Properties of a Biodegradable Magnesium Stent
Biomimicking Covalent Organic Frameworks Nanocomposite Coating for Integrated Enhanced Anticorrosion and Antifouling Properties of a Biodegradable Magnesium Stent
Available online 10 April 2024Author links open overlay panel, , , , , , , , , , , , , , , AbstractThe utilization of biod...
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