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Molecular landscape of ERBB2/HER2 gene amplification among patients with gynecologic malignancies; clinical implications and future directions
Molecular landscape of ERBB2/HER2 gene amplification among patients with gynecologic malignancies; clinical implications and future directions
Human epidermal growth factor receptor 2 (HER2) is tyrosine kinase receptor encoded by the ERBB2 gene [1]. ERBB2 amplifica...
Image-guided high-dose-rate brachytherapy as the method of choice in medically inoperable early-stage endometrial cancer patients
Image-guided high-dose-rate brachytherapy as the method of choice in medically inoperable early-stage endometrial cancer patients
With 130,051 new cases and 29,963 deaths in 2020 endometrial carcinoma remains the most common gynaecological malignancy i...
Concurrent uterine surgery and uptake of hormone therapy in patients undergoing bilateral salpingo-oophorectomy for risk-reducing or therapeutic indications
Concurrent uterine surgery and uptake of hormone therapy in patients undergoing bilateral salpingo-oophorectomy for risk-reducing or therapeutic indications
Ovarian cancer remains the most deadly gynecologic cancer, with less than half of patients living more than five years aft...
Factors associated with failed ‘test of cure’ in the NHS Cervical Screening Programme: A retrospective cohort study
Factors associated with failed ‘test of cure’ in the NHS Cervical Screening Programme: A retrospective cohort study
ObjectiveTo determine predictive factors associated with failed ‘test of cure’ (TOC) in the NHS Cervical Screening Program...
Let's chat about cervical cancer: Assessing the accuracy of ChatGPT responses to cervical cancer questions
Let's chat about cervical cancer: Assessing the accuracy of ChatGPT responses to cervical cancer questions
Artificial Intelligence (AI) is a rapidly evolving field with significant applications across many professions, including ...
Impact of postoperative morbidity on outcomes in patients with advanced epithelial ovarian cancer undergoing intestinal surgery at the time of primary or interval cytoreductive surgery: A Memorial Sloan Kettering Cancer Center Team Ovary study
Impact of postoperative morbidity on outcomes in patients with advanced epithelial ovarian cancer undergoing intestinal surgery at the time of primary or interval cytoreductive surgery: A Memorial Sloan Kettering Cancer Center Team Ovary study
In 2023, an estimated 19,710 women will be diagnosed with ovarian cancer and 13,270 patients will die from this disease in...
Molecular subtyping in endometrial cancer: A promising strategy to guide fertility preservation
Molecular subtyping in endometrial cancer: A promising strategy to guide fertility preservation
Endometrial cancer is the most common gynecologic malignancy in the United States. In 2023, an estimated 66,200 women will...
Ovarian cancer symptoms in pre-clinical invasive epithelial ovarian cancer – An exploratory analysis nested within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
Ovarian cancer symptoms in pre-clinical invasive epithelial ovarian cancer – An exploratory analysis nested within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
The trial protocol is available on the study website. The individual participant data that underlie the results reported i...
Integrating social care into gynecologic oncology: Identifying and addressing patient's social needs
Integrating social care into gynecologic oncology: Identifying and addressing patient's social needs
Cancer risk and health outcomes are affected by various factors, including biological/genetic predisposition, behavioral f...
Mapping sentinel lymph nodes in early-stage ovarian cancer (MELISA) trial - a further step towards lymphadenectomy replacement
Mapping sentinel lymph nodes in early-stage ovarian cancer (MELISA) trial - a further step towards lymphadenectomy replacement
Epithelial ovarian cancer (EOC) is detected at an early stage in up to 20% of patients, requiring complete staging surgery...
Oncologic outcomes of robot-assisted laparoscopy versus conventional laparoscopy for the treatment of apparent early-stage endometrioid adenocarcinoma of the uterus
Oncologic outcomes of robot-assisted laparoscopy versus conventional laparoscopy for the treatment of apparent early-stage endometrioid adenocarcinoma of the uterus
Endometrial cancer is the most common gynecologic cancer in the US, and most patients are diagnosed with early-stage disea...
Cervical cancer treatment update: A Society of Gynecologic Oncology clinical practice statement
Cervical cancer treatment update: A Society of Gynecologic Oncology clinical practice statement
Cervical cancer is the most commonly diagnosed gynecologic cancer worldwide. Although the incidence has declined with incr...
Impact of limiting reproductive rights of pregnant individuals with cancer in the United States
Impact of limiting reproductive rights of pregnant individuals with cancer in the United States
Available online 18 November 2023Author links open overlay panel, , , , , , , Section snippetsAuthor contributionsThis wor...
Immune checkpoint inhibitors with chemotherapy for primary advanced mismatch repair-deficient endometrial cancer: A cost-effectiveness analysis
Immune checkpoint inhibitors with chemotherapy for primary advanced mismatch repair-deficient endometrial cancer: A cost-effectiveness analysis
ObjectiveThe addition of immune checkpoint inhibitors (ICIs), pembrolizumab or dostarlimab, to paclitaxel and carboplatin ...
Major vessel resection for complete cytoreduction in primary advanced and recurrent ovarian malignancies: A case series and systematic review of the literature - pushing the boundaries in oncovascular surgery.
Major vessel resection for complete cytoreduction in primary advanced and recurrent ovarian malignancies: A case series and systematic review of the literature - pushing the boundaries in oncovascular surgery.
Volume 179, December 2023, Pages 42-51Author links open overlay panel, , , , , , , , , , , , , , Highlights•Oncovascular s...
Survival differences by race and surgical approach in early-stage operable cervical Cancer
Survival differences by race and surgical approach in early-stage operable cervical Cancer
Due to effective screening and dysplasia treatment, death from cervical cancer has dramatically decreased in American pati...
Disparities in brachytherapy utilization in cervical cancer in the United States: A comprehensive literature review
Disparities in brachytherapy utilization in cervical cancer in the United States: A comprehensive literature review
Early-stage cervical cancer is commonly treated with surgery while locally advanced disease is treated with definitive con...
Impact of postoperative residual disease on survival in epithelial ovarian cancer with consideration of recent frontline treatment advances: A systematic review and meta-analysis
Impact of postoperative residual disease on survival in epithelial ovarian cancer with consideration of recent frontline treatment advances: A systematic review and meta-analysis
Ovarian cancer is a leading cause of death from gynecological malignancies, with an estimated 313,959 new cases and 207,25...
Associations between modifiable lifestyle factors and health-related quality of life among endometrial carcinoma survivors - A cross-sectional study
Associations between modifiable lifestyle factors and health-related quality of life among endometrial carcinoma survivors - A cross-sectional study
ObjectiveTo explore possible associations between modifiable lifestyle factors and health-related quality of life (HRQoL) ...
Radical hysterectomy case volume and cervical cancer treatment in the era of COVID-19: A multi-site analysis of National Cancer Institute-designated Comprehensive Cancer Centers
Radical hysterectomy case volume and cervical cancer treatment in the era of COVID-19: A multi-site analysis of National Cancer Institute-designated Comprehensive Cancer Centers
Since 2000, the incidence of cervical cancer in the United States has declined due to screening and preventive HPV vaccina...
Aberrant nuclear β-catenin distribution does not prognosticate recurrences of endometrioid endometrial cancers – A retrospective single-institutional study
Aberrant nuclear β-catenin distribution does not prognosticate recurrences of endometrioid endometrial cancers – A retrospective single-institutional study
Endometrial cancer is the most common gynecologic malignancy in developed countries with a slow but constant rise in both ...
Vulvar squamous cell carcinoma in women 80 years and older: Treatment, survival and impact of comorbidities
Vulvar squamous cell carcinoma in women 80 years and older: Treatment, survival and impact of comorbidities
Vulvar cancer is a rare malignancy of the female genital tract, accounting for 3–9% of all gynecologic malignancies [1,2]....
High-fat diet and obesity are associated with differential angiogenic gene expression in epithelial ovarian cancer
High-fat diet and obesity are associated with differential angiogenic gene expression in epithelial ovarian cancer
Ovarian cancer (OC) is the most lethal gynecologic cancer in the United States with an estimated 207,252 deaths worldwide ...
Outcomes and toxicity in re-irradiation of gynecologic cancer: Systematic review of the Italian association of radiation and clinical oncology (AIRO)
Outcomes and toxicity in re-irradiation of gynecologic cancer: Systematic review of the Italian association of radiation and clinical oncology (AIRO)
In recent decades, thanks to technological improvements, we have seen an increased survival of patients with gynecological...
Niraparib and dostarlimab for the treatment of recurrent platinum-resistant ovarian cancer: results of a Phase II study (MOONSTONE/GOG-3032)
Niraparib and dostarlimab for the treatment of recurrent platinum-resistant ovarian cancer: results of a Phase II study (MOONSTONE/GOG-3032)
KeywordsDostarlimabNiraparibImmunotherapyPoly(ADP-ribose) polymerase inhibitorsPhase IIPlatinum-resistant ovarian cancerDa...
TERT promoter mutations and gene amplification in endometrial cancer
TERT promoter mutations and gene amplification in endometrial cancer
Volume 179, December 2023, Pages 16-23Author links open overlay panel, , , , , , , , , , , Highlights•TERT promoter hotspo...
Molecular determinants of clinical outcomes of pembrolizumab in recurrent ovarian cancer: Exploratory analysis of KEYNOTE-100
Molecular determinants of clinical outcomes of pembrolizumab in recurrent ovarian cancer: Exploratory analysis of KEYNOTE-100
ObjectiveThis prespecified exploratory analysis evaluated the association of gene expression signatures, tumor mutational ...
Intraluminal tumor cells and prognostic accuracy of endometrial cancer stage criteria: A multi-institution study
Intraluminal tumor cells and prognostic accuracy of endometrial cancer stage criteria: A multi-institution study
KeywordsUterus neoplasmFallopian tubeDisease-specific mortalityPatterns of spreadData availability statementThe data under...
Gynecologic cancer care in the first year of the COVID-19 pandemic
Gynecologic cancer care in the first year of the COVID-19 pandemic
Volume 178, November 2023, Pages 138-144Author links open overlay panel, , , , , , , Highlights•Between 9 and 10.4% of gyn...
Survival outcomes and establishment of a novel risk stratification system in patients with ovarian yolk sac tumors
Survival outcomes and establishment of a novel risk stratification system in patients with ovarian yolk sac tumors
KeywordsMalignant germ cell tumorsOvarian yolk sac tumorsSurvival outcomesPrognostic factorsRisk stratificationsAbbreviati...
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