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How to deal with frenemy NRF2: Targeting NRF2 for chemoprevention and cancer therapy
Induction of antioxidant proteins and phase 2 detoxifying enzymes that neutralize reactive electrophiles are important mec...
Cannabis sativa L.: A Comprehensive review on legislation, decriminalization, phytochemistry, antimicrobial activity, and safety
Throughout history, medicinal and aromatic plants have been used extensively to cure a variety of ailments. This article p...
Determination and evaluation of EPA and DHA ethyl esters in fish oils using the TMAH transesterification method
A simple and dependable technique, known as THAM method, has been developed to detect and measure ethyl eicosapentaenoate ...
Attenuation of diabetes-mediated muscle atrophy in rats by fish oil enriched omega-3 polyunsaturated fatty acids supplementation
Diabetes is associated with an increased risk of muscle wasting/atrophy, which adversely affects quality of life. We hypot...
An integrative approach for compressive quality control of RespireAidTM, a traditional Chinese medicine formula against SARS-CoV-2
RespireAid™ (NRICM101) is an effective anti-SARS-CoV-2 traditional Chinese medicine formula and has been licensed as a dru...
Cordycepin inhibits ERK pathway to suppress FGF9-induced tumorigenesis with MA-10 mouse Leydig tumor cells
Fibroblast growth factor 9 (FGF9) is a member of FGF family, and abnormal expression of FGF9 can promote tumorigenesis. Co...
Autophagy-urea cycle pathway is essential for the statin-mediated nitric oxide bioavailability in endothelial cells
Statins induce nitric oxide (NO) bioavailability by activating endothelial nitric oxide synthase via kinase- and calciumde...
What nature has to offer: Opportunities for immuno-oncology
Recent rapid development of cancer therapy has come about with the paradigm shift from the traditional goal of targeting c...
Preparation procedures of food and beverage samples for oxygen bomb calorimetry: A scoping review and reporting checklist
Standardised bomb calorimetry methods are essential to accurately quantify the gross energy within food and beverages, yet...
Electrochemically synthesized green fluorescent carbon dots for quantitation of hypochlorite and carbendazim
Green emission carbon dots (CDs) electrochemically prepared from 2,6-pyridinedicarboxylic acid and o-phenylenediamine were...
The inhibitory effect of quercetin-3-glucuronide on pulmonary injury in vitro and in vivo
Pulmonary injury is defined as a progressive inflammation. Extensive pro-inflammatory cytokines are secreted from alveolus...
Sleep-promoting activity of amylase-treated Ashwagandha (Withania somnifera L. Dunal) root extract via GABA receptors
Ashwagandha (Withania somnifera L. Dunal), an Indian medicinal plant that has been used for centuries to treat insomnia, e...
Selective detection of tricyclazole by optical technique using thiomalic acid–modified Au and Ag nanoparticle mixtures
This study proposes the use of thiomalic acid–modified Au and Ag nanoparticle mixtures (TMA-Au/AgNP mixes) for the selecti...
Chemometrics-assisted spectroscopic methods for rapid analysis of combined anti-malarial tablets
Combination of piperaquine (PQ) (320 mg) and dihydroartemisinin (DHA) (40 mg) is an anti-malarial formulation, which is re...
Urolithin A exhibits a neuroprotective effect against Alzheimer’s disease by inhibiting DYRK1A activity
Alzheimer’s disease (AD) is a devastating neurodegenerative disease with more than 50 million people suffer from it. Unfor...
Using lanthanide ions as magnetic and sensing probes for the detection of Tetracycline from complex samples
Tetracycline (TC) is a broad-spectrum antibiotic and has been added to animal feeds to grow livestock under healthy condit...
Recent developments in detection and therapeutic approaches for antibiotic-resistant bacterial infections
Owing to the widespread emergence and proliferation of antibiotic-resistant bacteria, the therapeutic benefits of antibiot...
Regulatory considerations for generic products of non-biological complex drugs
The Non-Biological Complex Drug (NBCD) Working Group defines an NBCD as “a medicinal product, not being a biological medic...
Erinacine S from Hericium erinaceus Mycelium Promotes Neuronal Regeneration by Inducing Neurosteroids Accumulation
Erinacines derived from Hericium erinaceus have been shown to possess various health benefits including neuroprotective ef...