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Trans-2-nonadecyl-4-(hydroxymethyl)-1,3-dioxolane (TNHD) purified from freshwater clams markedly alleviates dimethylnitrosamine-induced hepatic fibrosis
Liver fibrosis occurs due to injury or inflammation, which results in the excessive production of collagen and the formati...
Application and effectiveness of artificial intelligence for the border management of imported frozen fish in Taiwan
In Taiwan, the number of applications for inspecting imported food has grown annually and noncompliant products must be ac...
Pomelo (Citrus grandis (L.) Osbeck) sponge layers as a potential source of soluble dietary fiber: Evaluation of its physicochemical, structural and functional properties
Pomelo sponge layer (PSL) had been considered as a potential source of soluble dietary fiber (SDF), while they were mostly...
Effect of Indian gooseberry extract on improving methylglyoxal-associated leptin resistance in peripheral tissues of high-fat diet-fed rats
Increased leptin resistance and methylglyoxal (MG) levels are observed in obese patients. However, whether MG deposits con...
Ionizable copolymer functionalized magnetic nanocomposite as an adsorbent for boosting the extraction selectivity of aristolochic acids
Aristolochic acid nephropathy (AAN) has drawn increasing public attention. Organic anion transporters (OATs) are considere...
An auxiliary strategy of partial least squares regression in pharmacokinetic/pharmacodynamic studies: A case of application of guhong injection in myocardial ischemia/reperfusion rats
Guhong injection (GHI) has been applied in the therapy of cardio-cerebrovascular disease in clinic, but there is no report...
An acute herb-drug interaction of Magnoliae Officinalis Cortex with methotrexate via inhibiting multidrug resistance-associated protein 2
Magnoliae Officinalis Cortex (MOC), an herbal drug, contains polyphenolic lignans mainly magnolol (MN) and honokiol (HK). ...
Recent advances in combined Avant-garde technologies (thermal-thermal, non-thermal-non-thermal, and thermal-non-thermal matrix) to extract polyphenols from agro byproducts
Because food byproducts (waste) are rich in phytoconstituents, valorizing them is crucial for global food security. Howeve...
Therapeutic effects of orally administration of viable and inactivated probiotic strains against murine urinary tract infection
Urinary tract infections (UTIs) are highly prevalent bacterial infections that pose significant health risks. Specific pro...
Abundance of Prevotella copri in gut microbiota is inversely related to a healthy diet in patients with type 2 diabetes
While the gut microbiota is known to be influenced by habitual food intake, this relationship is seldom explored in type 2...
Investigation of microwave extraction of red cabbage and its neurotherapeutic potential
In the pursuit of bioactive compounds with health benefits from food and medicinal plants, optimization of process to redu...
Glycine-rich peptides from fermented Chenopodium formosanum sprout as an antioxidant to modulate the oxidative stress
Rhizopus oligosporus was utilized in the solid-state fermentation of Chenopodium formosanum sprouts (FCS) in a bioreactor....
Analysis and identification of phenolic compounds with antiproliferative activity from Chinese olive (Canarium album L.) fruit extract by HPLC-DAD-SPE-TT-NMR
Chinese olives (Canarium album L.) are rich in phenolic compounds, exhibiting a broad spectrum of potential clinical appli...
Steamed daylily flower (Hemerocallis fulva L.) protected cardiac and hepatic cells against ethanol induced apoptotic and oxidative damage
Our previous study examined the phytochemical composition and bio-activities of raw daylily flower (Hemerocallis fulva L.)...
Biological and clinical significance of the AGE-RAGE axis in the aggressiveness and prognosis of prostate cancer
Dietary factors and chronic hyperglycemia are linked to the formation of advanced glycation end products (AGEs) and prosta...
Dehulled Adlay (Coix lachryma-jobi L.) ameliorates hepatic gluconeogenesis and steatosis in streptozotocin/high-fat diet-induced diabetic rats
Adlay (Coix lachryma-jobi L.) is a traditional Chinese herbal medicine with various biological activities. We investigated...
Cryptocaryone induces apoptosis in human hepatocellular carcinoma cells by inhibiting aerobic glycolysis through Akt and c-Src signaling pathways
Hepatocellular carcinoma (HCC) is the most common form of liver cancer, with the second highest mortality rate in all canc...
An integrated strategy to evaluate active substances of Astragali Radix-Carthami Flos combination on the treatment of cerebral ischemia reperfusion injury based on TQSM polypharmacokinetics and pharmacodynamics
As a classic herb pair, Astragali Radix-Carthami Flos (AR-CF) has revealed good biological activity in the treatment of ce...
Isolation of GLP-1 enhancing indolizidine alkaloids from Boehmeria formosana
Boehmeria formosana, with its related species, demonstrates anti-glycemic effect, inhibition of HBV production, anti-cance...
Application of the US Food and Drug Administration’s Sentinel Routine Querying Tools to the Taiwan Sentinel Data Model-formatted National Health Insurance Research Database
The U.S. Food and Drug Administration’s Sentinel System is a leading distributed data network for drug safety surveillance...
Corrigendum to "SSR-based molecular diagnosis for Taiwan tea cultivars and its application in identifying cultivar composition of the processed tea"
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Effects of green tea–derived natural products on resistance exercise training in sarcopenia: A retrospective narrative mini-review
Skeletal muscle function deficits result in metabolic disease development and physical dysfunction in older adults. Sarcop...
How to deal with frenemy NRF2: Targeting NRF2 for chemoprevention and cancer therapy
Induction of antioxidant proteins and phase 2 detoxifying enzymes that neutralize reactive electrophiles are important mec...
Cannabis sativa L.: A Comprehensive review on legislation, decriminalization, phytochemistry, antimicrobial activity, and safety
Throughout history, medicinal and aromatic plants have been used extensively to cure a variety of ailments. This article p...
Determination and evaluation of EPA and DHA ethyl esters in fish oils using the TMAH transesterification method
A simple and dependable technique, known as THAM method, has been developed to detect and measure ethyl eicosapentaenoate ...
SSR-based molecular diagnosis for Taiwan tea cultivars and its application in identifying cultivar composition of the processed tea
Taiwan specialty teas are produced with distinct manufacturing processes from specific cultivars of tea plants in Camellia...
Attenuation of diabetes-mediated muscle atrophy in rats by fish oil enriched omega-3 polyunsaturated fatty acids supplementation
Diabetes is associated with an increased risk of muscle wasting/atrophy, which adversely affects quality of life. We hypot...
An integrative approach for compressive quality control of RespireAidTM, a traditional Chinese medicine formula against SARS-CoV-2
RespireAid™ (NRICM101) is an effective anti-SARS-CoV-2 traditional Chinese medicine formula and has been licensed as a dru...
Cordycepin inhibits ERK pathway to suppress FGF9-induced tumorigenesis with MA-10 mouse Leydig tumor cells
Fibroblast growth factor 9 (FGF9) is a member of FGF family, and abnormal expression of FGF9 can promote tumorigenesis. Co...
Identification for metabolism profiles and pharmacokinetic studies of tradition Chinese prescription Ji-Ming-San and its major metabolites in rats by UHPLC-Q-TOF-MS/MS and UHPLC-MS/MS
Ji-Ming-Shan (JMS) is a traditional prescription use for patients with rheumatism, tendons swelling, athlete's foot, ...
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