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Genetic alterations and allele frequency of BRAF V600E and TERT mutation in papillary thyroid carcinoma with intermediate-to-high recurrence risk: a retrospective study
Genetic alterations and allele frequency of BRAF V600E and TERT mutation in papillary thyroid carcinoma with intermediate-to-high recurrence risk: a retrospective study
The predictive value of allele frequency (AF) of BRAF V600E and TERT mutations in papillary thyroid carcinoma (PTC) remain...
Antinuclear antibodies may predict the development of immune-related adverse events in asymptomatic patients treated with immune checkpoint inhibitors: results from a single-center cohort
Antinuclear antibodies may predict the development of immune-related adverse events in asymptomatic patients treated with immune checkpoint inhibitors: results from a single-center cohort
We aim at investigating the association between subclinical autoimmunity and immune-related adverse events (irAEs) in a co...
Supporting the decision to perform molecular profiling for cancer patients based on routinely collected data through the use of machine learning
Supporting the decision to perform molecular profiling for cancer patients based on routinely collected data through the use of machine learning
Personalized medicine offers targeted therapy options for cancer treatment. However, the decision whether to include a pat...
A MiR181/Sirtuin1 regulatory circuit modulates drug response in biliary cancers
A MiR181/Sirtuin1 regulatory circuit modulates drug response in biliary cancers
Despite recent advances, biliary tract cancer (BTC) remains one of the most lethal tumor worldwide due to late diagnosis, ...
Investigation of long non-coding RNAs in extracellular vesicles from low-volume blood serum specimens of colorectal cancer patients
Investigation of long non-coding RNAs in extracellular vesicles from low-volume blood serum specimens of colorectal cancer patients
Colorectal cancer (CRC) is the second most prevalent cancer type worldwide, which highlights the urgent need for non-invas...
Low platelet count at diagnosis of anti-neutrophil cytoplasmic antibody-associated vasculitis is correlated with the severity of disease and renal prognosis
Low platelet count at diagnosis of anti-neutrophil cytoplasmic antibody-associated vasculitis is correlated with the severity of disease and renal prognosis
Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is an autoimmune disease that involves inflammation of blo...
Non-invasive prenatal test identifies circulating cell-free DNA chromosomal abnormalities derived from clonal hematopoiesis in aggressive hematological malignancies
Non-invasive prenatal test identifies circulating cell-free DNA chromosomal abnormalities derived from clonal hematopoiesis in aggressive hematological malignancies
Liquid biopsy is a minimally invasive diagnostic tool for identification of tumor-related mutations in circulating cell-fr...
The casual relationship between autoimmune diseases and multiple myeloma: a Mendelian randomization study
The casual relationship between autoimmune diseases and multiple myeloma: a Mendelian randomization study
Observational studies showed possible associations between systemic lupus erythematosus and multiple myeloma. However, whe...
Clinical features and prognosis of ANCA-associated vasculitis patients who were double-seropositive for myeloperoxidase-ANCA and proteinase 3-ANCA
Clinical features and prognosis of ANCA-associated vasculitis patients who were double-seropositive for myeloperoxidase-ANCA and proteinase 3-ANCA
Anti-neutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) patients with dual positivity for proteinase...
Role of albumin infusion in cirrhosis-associated complications
Role of albumin infusion in cirrhosis-associated complications
Cirrhosis is an advanced-stage liver disease that occurs due to persistent physiological insults such as excessive alcohol...
Development and validation of a novel prognostic nomogram for advanced diffuse large B cell lymphoma
Development and validation of a novel prognostic nomogram for advanced diffuse large B cell lymphoma
Advanced diffuse large B cell lymphoma (DLBCL) is a common malignant tumor with aggressive clinical features and poor prog...
Multi-omics and artificial intelligence predict clinical outcomes of immunotherapy in non-small cell lung cancer patients
Multi-omics and artificial intelligence predict clinical outcomes of immunotherapy in non-small cell lung cancer patients
In recent years, various types of immunotherapy, particularly the use of immune checkpoint inhibitors targeting programmed...
Interventional treatment of refractory non-traumatic chylous effusions in patients with lymphoproliferative disorders
Interventional treatment of refractory non-traumatic chylous effusions in patients with lymphoproliferative disorders
To report results of interventional treatment of refractory non-traumatic abdomino-thoracic chylous effusions in patients ...
Impact of age and cardiovascular risk factors on the incidence of adverse events in patients with rheumatoid arthritis treated with Janus Kinase inhibitors: data from a real-life multicentric cohort
Impact of age and cardiovascular risk factors on the incidence of adverse events in patients with rheumatoid arthritis treated with Janus Kinase inhibitors: data from a real-life multicentric cohort
Inhibiting Janus Kinases (JAK) is a crucial therapeutic strategy in rheumatoid arthritis (RA). However, the use of JAK inh...
External validation of a four-tiered grading system for chromophobe renal cell carcinoma
External validation of a four-tiered grading system for chromophobe renal cell carcinoma
This study aimed to validate the prognostic value of a four-tiered grading system recently proposed by Avulova et al. and ...
Investigating the role of circulating tumor cells in gastric cancer: a comprehensive systematic review and meta-analysis
Investigating the role of circulating tumor cells in gastric cancer: a comprehensive systematic review and meta-analysis
Investigating the role of circulating tumor cells (CTCs) and their characteristics is still controversial in patients with...
Cysteine- and glycine-rich protein 1 predicts prognosis and therapy response in patients with acute myeloid leukemia
Cysteine- and glycine-rich protein 1 predicts prognosis and therapy response in patients with acute myeloid leukemia
Acute myeloid leukemia (AML) is a heterogeneous disease with a poor prognosis. The current risk stratification system is e...
Extracellular matrix protein 1 (ECM1) is a potential biomarker in B cell acute lymphoblastic leukemia
Extracellular matrix protein 1 (ECM1) is a potential biomarker in B cell acute lymphoblastic leukemia
B cell acute lymphoblastic leukemia (ALL) is characterized by the highly heterogeneity of pathogenic genetic background, a...
Non-tumor-related prognostic factors for immunotherapy–chemotherapy or immunotherapy alone as first-line in advanced non-small cell lung cancer (NSCLC)
Non-tumor-related prognostic factors for immunotherapy–chemotherapy or immunotherapy alone as first-line in advanced non-small cell lung cancer (NSCLC)
Besides programmed death ligand 1 (PD-L1) expression, rapid, cost-effective and validated scores or models are critical fo...
Advances in epigenetic alterations of chronic lymphocytic leukemia: from pathogenesis to treatment
Advances in epigenetic alterations of chronic lymphocytic leukemia: from pathogenesis to treatment
Chronic lymphocytic leukemia (CLL) is a heterogeneous disease with alterations in genetic expression and epigenetic modifi...
Circulating Bone morphogenetic protein 9 (BMP9) as a new biomarker for noninvasive stratification of nonalcoholic fatty liver disease and metabolic syndrome
Circulating Bone morphogenetic protein 9 (BMP9) as a new biomarker for noninvasive stratification of nonalcoholic fatty liver disease and metabolic syndrome
Nonalcoholic fatty liver disease (NAFLD) is closely related to metabolic syndrome (MetS). Bone morphogenetic protein 9 (BM...
Whole-exome sequencing is feasible on a fresh-frozen skin sample of intravascular large B cell lymphoma
Whole-exome sequencing is feasible on a fresh-frozen skin sample of intravascular large B cell lymphoma
Intravascular large B-cell lymphoma (IVLBCL) is a rare aggressive extranodal non-Hodgkin lymphoma. The predominant, if not...
RUNX transcription factors: biological functions and implications in cancer
RUNX transcription factors: biological functions and implications in cancer
Runt-related transcription factors (RUNX) are a family of transcription factors that are essential for normal and malignan...
Sex-specific differences in ICOS+ T helper cell differentiation in systemic lupus erythematosus patients with low disease activity
Sex-specific differences in ICOS+ T helper cell differentiation in systemic lupus erythematosus patients with low disease activity
Systemic lupus erythematosus (SLE) is a sex biased chronic autoimmune disease affecting predominantly females during repro...
Lymphoma relapse 1 year or later after immunochemotherapy in DLBCL patients: clinical features and outcome
Lymphoma relapse 1 year or later after immunochemotherapy in DLBCL patients: clinical features and outcome
Despite great advances in treatment, 30–40% of patients with DLBCL undergo relapses. Patients with a relapse within ...
Research progress on the multi-omics and survival status of circulating tumor cells
Research progress on the multi-omics and survival status of circulating tumor cells
In the dynamic process of metastasis, circulating tumor cells (CTCs) emanate from the primary solid tumor and subsequently...
Therapeutic potential of mesenchymal stem cell-derived exosomes for regenerative medicine applications
Therapeutic potential of mesenchymal stem cell-derived exosomes for regenerative medicine applications
Mesenchymal stem cell-derived exosomes have emerged as a promising cell-free therapy for tissue engineering. Compared to i...
Elevated CD169 expressing monocyte/macrophage promotes systemic inflammation and disease progression in cirrhosis
Elevated CD169 expressing monocyte/macrophage promotes systemic inflammation and disease progression in cirrhosis
Systemic inflammation is related to disease progression and prognosis in patients with advanced cirrhosis. However, the me...
Development and evaluation of nomograms and risk stratification systems to predict the overall survival and cancer-specific survival of patients with hepatocellular carcinoma
Development and evaluation of nomograms and risk stratification systems to predict the overall survival and cancer-specific survival of patients with hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, and patients with HCC have a poor prognosi...
Clinical and pathological findings of IgA nephropathy following SARS-CoV-2 infection
Clinical and pathological findings of IgA nephropathy following SARS-CoV-2 infection
The features of IgA nephropathy (IgAN) after SARS-CoV-2 infection have not been well characterized. In this study, we comp...
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