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Withdrawn: circLgr4 drives colorectal tumorigenesis and invasion through Lgr4‐targeting peptide
Withdrawn: circLgr4 drives colorectal tumorigenesis and invasion through Lgr4‐targeting peptide
Xiaofei Zhi, Jiaxuan Zhang, Zhouyang Cheng, Longjun Bian, Jun Qin. circLgr4 drives colorectal tumorigenesis and invasion t...
Real‐world evidence of adjuvant gemcitabine plus capecitabine vs gemcitabine monotherapy for pancreatic ductal adenocarcinoma
Real‐world evidence of adjuvant gemcitabine plus capecitabine vs gemcitabine monotherapy for pancreatic ductal adenocarcinoma
Abstract The added value of capecitabine to adjuvant gemcitabine monotherapy (GEM) in pancreatic ductal adenocarcinoma (PD...
Survival outcomes of patients with nonsmall cell lung cancer concomitantly receiving proton pump inhibitors and immune checkpoint inhibitors
Survival outcomes of patients with nonsmall cell lung cancer concomitantly receiving proton pump inhibitors and immune checkpoint inhibitors
Abstract Recent evidence suggests that gut microbiota dysbiosis adversely affects the efficacy of immune checkpoint inhibi...
Comparison of adverse drug reactions between tamoxifen and toremifene in breast cancer patients with different CYP2D6 genotypes: a propensity‐score matched cohort study
Comparison of adverse drug reactions between tamoxifen and toremifene in breast cancer patients with different CYP2D6 genotypes: a propensity‐score matched cohort study
Abstract CYP2D6 gene polymorphism had a profound impact upon the effect of tamoxifen as adjuvant endocrine therapy in brea...
Changes in general and central fatness are associated with hepatocellular carcinoma: A Korean nationwide longitudinal study
Changes in general and central fatness are associated with hepatocellular carcinoma: A Korean nationwide longitudinal study
Abstract We investigated the impact of short-term changes in general and central fatness on the risk of hepatocellular car...
Diverging incidence trends of oral tongue cancer compared to other head and neck cancers in young adults in France
Diverging incidence trends of oral tongue cancer compared to other head and neck cancers in young adults in France
Abstract While head and neck cancer incidence decreased worldwide due to reduced tobacco and alcohol consumption, oral ton...
PARP mediated DNA damage response, genomic stability and immune responses
PARP mediated DNA damage response, genomic stability and immune responses
Abstract Poly (ADP-ribose) polymerase (PARP) enzymes, especially PARP1, play important roles in the DNA damage response an...
Cancer Risk in Patients With Bipolar Disorder and Unaffected Siblings of Such Patients: A Nationwide Population‐Based Study
Cancer Risk in Patients With Bipolar Disorder and Unaffected Siblings of Such Patients: A Nationwide Population‐Based Study
Abstract Increasing evidence suggests that patients with bipolar disorder are more likely to develop malignant cancer than...
Real‐world evidence of adjuvant gemcitabine plus capecitabine versus gemcitabine monotherapy for pancreatic ductal adenocarcinoma
Real‐world evidence of adjuvant gemcitabine plus capecitabine versus gemcitabine monotherapy for pancreatic ductal adenocarcinoma
Abstract The added value of capecitabine to adjuvant gemcitabine monotherapy (GEM) in pancreatic ductal adenocarcinoma (PD...
Progesterone receptor isoform ratio dictates antiprogestin/progestin effects on breast cancer growth and metastases: A role for NDRG1
Progesterone receptor isoform ratio dictates antiprogestin/progestin effects on breast cancer growth and metastases: A role for NDRG1
Abstract Progesterone receptors (PR) ligands are being tested in luminal breast cancer. There are mainly two PR isoforms, ...
Treatment of hepatocellular carcinoma with autologous platelets encapsulating sorafenib or lenvatinib: a novel therapy exploiting tumor‐platelet interactions
Treatment of hepatocellular carcinoma with autologous platelets encapsulating sorafenib or lenvatinib: a novel therapy exploiting tumor‐platelet interactions
Abstract Hepatocellular carcinoma (HCC) activates platelets through the action of adjacent sinusoidal cells. Activated pla...
COVID‐19 and Access to Cancer Care in Kenya: Patient Perspective
COVID‐19 and Access to Cancer Care in Kenya: Patient Perspective
Abstract COVID-19 disruptions severely impacted access to health services for non-communicable diseases, including cancer,...
mdm2 gene amplification is associated with luminal breast cancer progression in humanized PDX mice and a worse outcome of estrogen receptor positive disease
mdm2 gene amplification is associated with luminal breast cancer progression in humanized PDX mice and a worse outcome of estrogen receptor positive disease
Abstract Estrogen receptor-positive breast cancer is a highly prevalent but heterogeneous disease among women. Advanced mo...
Complexity against current cancer research – are we on the wrong track?
Complexity against current cancer research – are we on the wrong track?
Abstract Cancer genetics has led to major discoveries, including proto-oncogene and tumor-suppressor concepts, and cancer ...
Endometrial cancer prognosis in women with endometriosis and adenomyosis. A retrospective nationwide cohort study of 40,840 women.
Endometrial cancer prognosis in women with endometriosis and adenomyosis. A retrospective nationwide cohort study of 40,840 women.
Abstract We aim to compare endometrial cancer survival in women with or without histological proven endometriosis or adeno...
Microenvironment and drug resistance in acute myeloid leukemia: do we know enough?
Microenvironment and drug resistance in acute myeloid leukemia: do we know enough?
Abstract Acute myeloid leukemia (AMLs), as the name suggests, often develop suddenly and are very progressive forms of can...
Comparative performance of the human papillomavirus test and cytology for primary screening for high‐grade cervical intraepithelial neoplasia at the population level
Comparative performance of the human papillomavirus test and cytology for primary screening for high‐grade cervical intraepithelial neoplasia at the population level
Abstract The World Health Organization recommends high-risk human papillomavirus (hrHPV)-based screening for women 39-49&#...
90‐day mortality and clinical outcomes of patients with solid tumours and COVID‐19 infection during the first pandemic outbreak in Catalonia, Spain: a multicentre retrospective study
90‐day mortality and clinical outcomes of patients with solid tumours and COVID‐19 infection during the first pandemic outbreak in Catalonia, Spain: a multicentre retrospective study
Abstract To describe the clinical outcomes and risk factors for 90-day mortality in patients with solid tumours (ST) and C...
Changes in weight and waist circumference during menopausal transition and postmenopausal breast cancer risk
Changes in weight and waist circumference during menopausal transition and postmenopausal breast cancer risk
Abstract This study aimed to investigate the association between changes in weight and waist circumference (WC) during men...
Increased survival disparities among children and adolescents & young adults with acute myeloid leukemia: A Dutch population‐based study
Increased survival disparities among children and adolescents & young adults with acute myeloid leukemia: A Dutch population‐based study
Abstract For many cancers, adolescents and young adults (AYAs) have a poorer prognosis than pediatric patients. Our study ...
Adult T‐cell leukemia‐lymphoma acquires resistance to DNA demethylating agents through dysregulation of enzymes involved in pyrimidine metabolism
Adult T‐cell leukemia‐lymphoma acquires resistance to DNA demethylating agents through dysregulation of enzymes involved in pyrimidine metabolism
Abstract Adult T-cell leukemia-lymphoma (ATL) is an aggressive neoplasm derived from T-cells transformed by human T-cell l...
Large‐scale topological disruption of chromosome territories 9 and 22 is associated with nonresponse to treatment in CML
Large‐scale topological disruption of chromosome territories 9 and 22 is associated with nonresponse to treatment in CML
Abstract Chronic Myeloid Leukemia (CML) is a myeloproliferative neoplasm defined by the presence of t(9;22) translocation ...
Overall survival benefit of Osimertinib and clinical value of upfront cranial local therapy in untreated EGFR‐mutant non‐small cell lung cancer with brain metastasis
Overall survival benefit of Osimertinib and clinical value of upfront cranial local therapy in untreated EGFR‐mutant non‐small cell lung cancer with brain metastasis
Abstract Osimertinib, as a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), showe...
Selenium and cancer risk: wide‐angled Mendelian randomization analysis
Selenium and cancer risk: wide‐angled Mendelian randomization analysis
Abstract Evidence on the association between selenium and cancer risk is inconclusive. We conducted a Mendelian randomizat...
Reductionism that leads to manuscript rejection
Reductionism that leads to manuscript rejection
Corresponding Author Hinrich Gronemeyer Department of Func...
Acceleration of Cervical Cancer Diagnosis with Human Papillomavirus Testing Below Age 30: Observational Study
Acceleration of Cervical Cancer Diagnosis with Human Papillomavirus Testing Below Age 30: Observational Study
Abstract Several international cervical screening guidelines advise against using high-risk human papillomavirus (HR-HPV) ...
Impact of specific high‐risk human papillomavirus genotypes on survival in oropharyngeal cancer
Impact of specific high‐risk human papillomavirus genotypes on survival in oropharyngeal cancer
Abstract The increases observed in incidence and survival of oropharyngeal squamous cell carcinoma (OPSCC) have been attri...
Comprehensive clinicopathologic study of alpha fetoprotein‐expression in a large cohort of patients with hepatocellular carcinoma
Comprehensive clinicopathologic study of alpha fetoprotein‐expression in a large cohort of patients with hepatocellular carcinoma
Abstract Alpha fetoprotein (AFP) is the most widely used diagnostic and prognostic serum biomarker for HCC. Despite its wi...
Diverging incidence trends of oral tongue cancer compared with other head and neck cancers in young adults in France
Diverging incidence trends of oral tongue cancer compared with other head and neck cancers in young adults in France
Abstract While head and neck cancer (HNC) incidence decreased worldwide due to reduced tobacco and alcohol consumption, or...
Gestational age and cancer risk up to young adulthood in Swedish population born 1974 to 2013: A population‐based cohort study
Gestational age and cancer risk up to young adulthood in Swedish population born 1974 to 2013: A population‐based cohort study
Abstract We examined the association between gestational age and risk of any primary cancer and observed whether the risk ...
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