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Etoposide: A rider on the cytokine storm
Volume 168, August 2023, 156234Author links open overlay panelAbstractFor more than 40 years, the epipodophyllotoxin drug ...
TNF-α/STAT1/CXCL10 mutual inflammatory axis that contributes to the pathogenesis of experimental models of multiple sclerosis: A promising signaling pathway for targeted therapies
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) that affects more than 2.5 million pe...
Matrix metalloproteinases −2 and −9 expression in dogs with visceral leishmaniasis: A systematic review
Visceral leishmaniasis (VL) is an endemic disease in several countries caused by the protozoan Leishmania infantum and is ...
The neurotoxic branch of the kynurenine pathway is highly activated in the central nervous system of patients with pneumococcal meningitis
The most common etiological agents of acute bacterial meningitis (ABM) are Streptococcus pneumoniae and Neisseria meningit...
Exosomes from chondrocytes overexpressing miR-214-3p facilitate M2 macrophage polarization and angiogenesis to relieve Legg Calvé-Perthes disease
LCPD is an idiopathic osteonecrosis, which is mainly manifested by necrosis of femoral head and cartilage induced by inter...
The dynamic changes of monocytes and cytokines during wound healing post-burn injury
Burns are among the most devastating injuries, representing a major global public health crisis [1], [2], [3], especially ...
The relationship between host defense peptides and adrenal steroids. An account of reciprocal influences
Tuberculosis (TB) accounts for increased morbidity and mortality across the world. Approximately 10 million new TB cases e...
Chronic Epstein-Barr virus infection: A potential junction between primary Sjögren’s syndrome and lymphoma
Primary Sjögren’s syndrome (pSS) is an autoimmune disorder that progresses slowly and has a low incidence and fatality rat...
Colorable role of interleukin (IL)-6 in obesity hypertension: A hint from a Chinese adult case-control study
Obesity and hypertension are major risk factors for cardiovascular diseases that affect millions of people worldwide [1], ...
Cytomegalovirus seropositivity correlates with both human β-defensin 1 and IFN-γ downregulation in women with obesity
Obesity is characterized by a chronic systemic inflammation and a chronic low-grade inflammation in adipose tissue [1]. Ob...
Impact of COVID-19 and vaccination on first and second trimester screening results
COVID-19 has been shown to affect pregnant women. Since pregnant women are at risk of this infection, vaccination against ...
Streptococcus lactarius MB622 and Streptococcus salivarius MB620 isolated from human milk reduce chemokine IL-8 production in response to TNF-α in Caco-2 cell line, an exploratory study
Human milk has an ability to protect against GI infections and supplies balanced and adequate nutrient contents to the inf...
What defines a chemokine? – The curious case of CXCL17
In this article, we provide a critique of the literature regarding the discovery of CXCL17 and key aspects of CXCL17 biolo...
Retraction notice to “Inhibition of the p38-MAPK signaling pathway suppresses the apoptosis and expression of proinflammatory cytokines in human osteoarthritis chondrocytes” [Cytokine 90 (2017) 135–143]
Volume 168, August 2023, 156223Author links open overlay panelHe-Yan Sun, Kong-Zu Hu, Zong-Sheng YinShow morePrevious arti...
Corrigendum to “ADAR1 prevents small intestinal injury from inflammation in a murine model of sepsis” [Cytokine 104 (2018) 30–37]
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Gene deletion of Interleukin-1α reduces ER stress-induced CHOP expression in macrophages and attenuates the progression of atherosclerosis in apoE-deficient mice
Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of morbidity and mortality worldwide that is associated ...
Significant association of MCP1 rs1024611 and CCR2 rs1799864 polymorphisms with colorectal cancer and liver metastases susceptibility and aggressiveness: A case-control study
Colorectal cancer (CRC) is a significant global health concern [1], [2]. Incidence among men exhibits 1.2-fold higher than...
Corrigendum to “LncRNA ROR promotes NLRP3-mediated cardiomyocyte pyroptosis by downregulating FOXP1 via interactions with PTBP1” [Cytokine 152 (2022) 155812]
Volume 167, July 2023, 156209Author links open overlay panelMin Zeng a 1, Shijiang Yi b 1, Yunbin Xiao a, Zhi Chen aShow m...
Gene deletion of Interleukin-1α reduces ER stress-induced CHOP expression in macrophages and attenuates the progression of atherosclerosis in apoE-deficient mice
Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of morbidity and mortality worldwide that is associated ...
The fetal response to maternal inflammation is dependent upon maternal IL-6 in a murine model
BackgroundThe induction of maternal inflammation in mice leads to fetal injury that is believed to be IL-6 dependent. The ...
The correlation of serum musclin with diabetic nephropathy
The diabetes prevalence is increasing with decades all over the world [1]. Diabetic nephropathy (DN), the most prevalent m...
IDO/Kynurenine; novel insight for treatment of inflammatory diseases
Inflammation is a defense mechanism in the body. The immune system recognizes harmful and external factors, and in return,...
Low serum Klotho reflects senile inflammation in middle-aged and elderly patients with coronary atherosclerosis
Coronary atherosclerotic disease (CAD) is one of the leading causes for cardiovascular mortality and is an urgent public h...
Interferon-gamma (IFN-γ): Reviewing its mechanisms and signaling pathways on the regulation of endothelial barrier function
Interferon-gamma (IFN-γ) is well known for its immunomodulatory activity; however, it is worth to mention that IFN-γ is al...
Targeted blockade of interleukin-8 negates metastasis and chemoresistance via Akt/Erk-NFκB axis in oral cancer
Oral cancer is amongst the top three cancers in India [1], [2]. Almost 90 % of the oral cancers are identified as squamous...
Protective effects of methylprednisolone–cyclophosphamide treatment on bleomycin-induced pulmonary fibrosis
KeywordsPulmonary fibrosisMethylprednisolone and cyclophosphamide combinationInflammationOxidative stressT-cell immunityAb...
Effect of nitric oxide synthase gene polymorphism on inflammatory response in patients with chronic obstructive pulmonary disease
This study aimed to investigate the association between nitric oxide synthase gene polymorphisms and the inflammatory resp...
sFlt-1-enriched exosomes induced endothelial cell dysfunction and a preeclampsia-like phenotype in mice
Volume 166, June 2023, 156190Author links open overlay panel, , , , , , , , , , Highlights•sFlt-1 (soluble fms-like tyrosi...
Increased neutrophil derived chemokines (CXCL10 and CCL2) in human trichinellosis as possible serological markers of the polarization of the immune response against the parasite
Trichinella britovi belongs to the encapsulated clade of the Trichinella genus. It is a widely distributed parasitic nemat...
Cardiac disturbances and changes in tissue cytokine levels in mice fed with a high-refined carbohydrate diet
The association of carbohydrate intake with cardiovascular diseases (CVD) has been overshadowed by the premise that dietar...
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