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Electrospun fibers loaded with antimicrobial peptides for treatment of wound infections
The widespread resistance of clinically relevant bacteria against established antibiotics emphasizes the urgent need for n...
Effect of fluid velocity and particle size on the hydrodynamic diffusion layer thickness
The aim of this study was to determine the thickness of the hydrodynamic diffusion layer (hHDL) of three poor water-solubl...
Antifungal nanosuspensions with surfactants and silver for the treatment of onychomycosis
Fungal nail infection (Onychomycosis) often requires prolonged treatment and is associated with a high risk of resistance ...
Novel drug delivery systems: Emerging development opportunities and translational challenges
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Direct visualizing of paracetamol immediate release tablet disintegration in vivo and in vitro
The purpose of the present study was to study tablet disintegration by direct visualization, in vivo and in vitro. Based o...
Self-assembling branched amphiphilic peptides for targeted delivery of small molecule anticancer drugs
Water insolubility poses a significant challenge in the clinical applications of many small molecule drugs. To improve the...
Pulmonary delivery of liposomes co-loaded with SN38 prodrug and curcumin for the treatment of lung cancer
SN387-ethyl-10-hydroxyl camptothecinCPPcell-penetrating peptideNSCLCnon-small cell lung cancerSCLCsmall cell lung cancerPT...
Zinc insulin hexamer loaded alginate zinc hydrogel: preparation, characterization and in vivo hypoglycemic ability
Available online 7 September 2022Highlights•Alginate zinc hydrogel loaded with zinc insulin hexamer was prepared;•Alginate...
Platensimycin-berberine chloride co-amorphous drug system: Sustained release and prolonged half-life
Available online 7 September 2022AbstractCo-amorphous technology is an emerging approach for pharmaceutical engineering of...
Graphene quantum dots as bimodal imaging agent for X-ray and Computed Tomography
The urgency of new contrast agents, especially for X-ray and Computed Tomography (CT) is increasing each day. Although bot...
Nanobiosensors for detection of opioids: A review of latest advancements
Opioids are generally used as analgesics in pain treatment. Like many drugs, they have side effects when overdosed and can...
Thiolation of non-ionic surfactants for the development of lipid-based mucoadhesive drug delivery systems
The aim of this study was to develop thiolated self-emulsifying drug delivery systems (SEDDS) and nanostructured lipid car...
Gold nanorods-loaded hydrogel-forming needles for local hyperthermia applications: Proof of concept
PPTTPlasmonic photothermal therapyHFLNHydrogel- forming long needleNMSCsNon- melanoma skin cancersSCCSquamous cell carcino...
Evaluation of adsorption of DNA/PEI polyplexes to tubing materials
Nucleic acid drugs hold great promise for potential treatment of a variety of diseases. But efficient delivery is still th...