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Influence of BAKs on tear film lipid layer: In vitro and in silico models
Ocular rosacea is a chronic inflammatory disorder with periods of exacerbation and remission, often underdiagnosed in chil...
Fed Intestinal Solubility Limits and Distributions Applied to the Developability Classification System
For solid oral dosage forms drug solubility in intestinal fluid is an important parameter influencing product performance ...
Study on Sgc8 aptamer-mediated nucleic acid nanomaterial-doxorubicin complex for tumor targeted therapy
Nowadays, malignancies continue to be a major problem affecting human health worldwide. According to a study of cancer dat...
Evaluation of binders in twin-screw wet granulation – Optimal combination of binder and disintegrant
Tablets are frequently used solid oral dosage forms. Besides the identity, purity and content of the active pharmaceutical...
Seborrheic dermatitis: topical therapeutics and formulation design
Seborrheic dermatitis (SD) affects approximately 1–3 % of the adult population, causing skin inflammation, pronounced flak...
Thermal investigation on hydrated co-amorphous systems of nicotinamide and prilocaine
It is generally recognized that water, acting as a plasticizer, increases molecular mobility, leading to a decrease of the...
Drilling down the bioequivalence assessment of topical antifungal products: Microstructure and release
In recent years, the regulatory mechanisms for topical generic product bioequivalence (BE) assessment have been subjected ...
A triple crosslinked micelle-hydrogel lacrimal implant for localized and prolonged therapy of glaucoma
Glaucoma is the main trigger of global irreversible vision loss. Because of the growingly aging population, it has been pr...
Patient engagement in pharmaceutical development: Where are we? – Report from a symposium
Pharmaceutical companies are tasked with developing life-changing products that meet the needs of patients while adhering ...
Nanodelivery systems for cutaneous melanoma treatment
5-ALA5-Aminolevulinic Acid5hmC5-HydroxymethylcytosineAIDSAcquired Immune Deficiency SyndromeAJCCAmerican Joint Committee o...