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Quantifying non-transferrin-bound iron (NTBI) in human plasma: incorporating BODIPY-pyridylhydrazone (BODIPY-PH) within a thin green film linked to a portable fluorescence-based device
Quantifying non-transferrin-bound iron (NTBI) in human plasma: incorporating BODIPY-pyridylhydrazone (BODIPY-PH) within a thin green film linked to a portable fluorescence-based device
Free iron in human serum or non-transferrin-bound iron (NTBI) can generate free radicals and lead to oxidative damage. Mor...
The rise and fall of adenine clusters in the gas phase: a glimpse into crystal growth and nucleation
The rise and fall of adenine clusters in the gas phase: a glimpse into crystal growth and nucleation
The emergence of a crystal nucleus from disordered states is a critical and challenging aspect of the crystallization proc...
Structural characterization of wax esters using ultraviolet photodissociation mass spectrometry
Structural characterization of wax esters using ultraviolet photodissociation mass spectrometry
Wax esters play critical roles in biological systems, serving functions from energy storage to chemical signaling. Their d...
Enhancing electrochemical detection through machine learning-driven prediction for canine mammary tumor biomarker with green silver nanoparticles
Enhancing electrochemical detection through machine learning-driven prediction for canine mammary tumor biomarker with green silver nanoparticles
This study developed an innovative biosensor strategy for the sensitive and selective detection of canine mammary tumor bi...
Facile biotic/abiotic sandwich detection system for the highly sensitive detection of human serum albumin and glycated albumin
Facile biotic/abiotic sandwich detection system for the highly sensitive detection of human serum albumin and glycated albumin
Quantifying glycated albumin (GA) levels in the blood is crucial for diagnosing diabetes because they strongly correlate w...
Tailoring metal oxide nanozymes for biomedical applications: trends, limitations, and perceptions
Tailoring metal oxide nanozymes for biomedical applications: trends, limitations, and perceptions
Nanomaterials with enzyme-like properties are known as ‘nanozymes’. Nanozymes are preferred over natural enzym...
Artificial intelligence-based plasma exosome label-free SERS profiling strategy for early lung cancer detection
Artificial intelligence-based plasma exosome label-free SERS profiling strategy for early lung cancer detection
As a lung cancer biomarker, exosomes were utilized for in vitro diagnosis to overcome the lack of sensitivity of conventio...
Real-time monitoring of cellular superoxide anion release in THP-1 cells using a catalytically amplified superoxide dismutase–based microbiosensor
Real-time monitoring of cellular superoxide anion release in THP-1 cells using a catalytically amplified superoxide dismutase–based microbiosensor
Reactive oxygen species (ROS) including the superoxide anion (O2•−) are typically studied in cell cultures usi...
Subzero project: comparing trace element profiles of enriched mitochondria fractions from frozen and fresh liver tissue
Subzero project: comparing trace element profiles of enriched mitochondria fractions from frozen and fresh liver tissue
From organs to subcellular organelles, trace element (TE) homeostasis is fundamental for many physiological processes. Whi...
SERS and electrochemical dual-mode detection of miRNA-141 by using single Au@Ag nanowire as a new platform
SERS and electrochemical dual-mode detection of miRNA-141 by using single Au@Ag nanowire as a new platform
As biomarkers of cancer, the accurate and sensitive detection of microRNAs is of great significance. Therefore, we propose...
Rigorous scientific inquiry guided by creativity, curiosity and support: One of the last Renaissance scientists of our time
Rigorous scientific inquiry guided by creativity, curiosity and support: One of the last Renaissance scientists of our time
“Most of the work still to be done in science and the useful arts is pr...
Combination of real-time and hyphenated mass spectrometry for improved characterisation of exhaled breath biomarkers in clinical research
Combination of real-time and hyphenated mass spectrometry for improved characterisation of exhaled breath biomarkers in clinical research
Exhaled breath volatilomics is a powerful non-invasive tool for biomarker discovery in medical applications, but compound ...
Rapid immunochemical methods for the analysis of proquinazid in strawberry QuEChERS extracts
Rapid immunochemical methods for the analysis of proquinazid in strawberry QuEChERS extracts
Proquinazid is a new-generation fungicide authorized in the EU for combating powdery mildew infections in high-value crops...
Rapid analysis of untreated food samples by gel loading tip spray ionization mass spectrometry
Rapid analysis of untreated food samples by gel loading tip spray ionization mass spectrometry
Rapid, efficient, versatile, easy-to-use, and non-expensive analytical approaches are globally demanded for food analysis....
Establishment of a multi-line immunochromatography based on magnetic nanoparticles for simultaneous screening of multiple biomarkers
Establishment of a multi-line immunochromatography based on magnetic nanoparticles for simultaneous screening of multiple biomarkers
Biomarkers screening is a benefit approach for early diagnosis of major diseases. In this study, magnetic nanoparticles (M...
Quantitative comparison of bile acid glucuronides sub-metabolome between intrahepatic cholestasis and healthy pregnant women
Quantitative comparison of bile acid glucuronides sub-metabolome between intrahepatic cholestasis and healthy pregnant women
Because of the pathological indication and the physiological functions, bile acids (BAs) have occupied the research hotspo...
A stochastic approach for parameter optimization of feature detection algorithms for non-target screening in mass spectrometry
A stochastic approach for parameter optimization of feature detection algorithms for non-target screening in mass spectrometry
Feature detection plays a crucial role in non-target screening (NTS), requiring careful selection of algorithm parameters ...
Development of a supramolecular solvent–based extraction method for application to quantitative analyses of a wide range of organic contaminants in indoor dust
Development of a supramolecular solvent–based extraction method for application to quantitative analyses of a wide range of organic contaminants in indoor dust
This study investigates the efficacy of supramolecular solvent (SUPRAS) in extracting a diverse spectrum of organic contam...
Progress, applications, and challenges in high-throughput effect-directed analysis for toxicity driver identification — is it time for HT-EDA?
Progress, applications, and challenges in high-throughput effect-directed analysis for toxicity driver identification — is it time for HT-EDA?
The rapid increase in the production and global use of chemicals and their mixtures has raised concerns about their potent...
GC × GC-HRMS with complementary ionization methods in the suspect screening analysis of fragrance allergens: overwhelming or justified?
GC × GC-HRMS with complementary ionization methods in the suspect screening analysis of fragrance allergens: overwhelming or justified?
Modern gas chromatography-mass spectrometry (GC–MS) allows for the analysis of complex samples, such as fragrances. ...
Pipette-tip solid-phase extraction coupled with matrix-assisted laser desorption/ionization mass spectrometry enables rapid and high-throughput analysis of antidepressants in rat serum
Pipette-tip solid-phase extraction coupled with matrix-assisted laser desorption/ionization mass spectrometry enables rapid and high-throughput analysis of antidepressants in rat serum
Therapeutic drug monitoring is essential for ensuring the efficacy and safety of medications. This study introduces a stre...
Soft ionization mechanisms in flexible µ-tube plasma—elucidation of He-, Ar-, Kr-, and Xe-FµTP
Soft ionization mechanisms in flexible µ-tube plasma—elucidation of He-, Ar-, Kr-, and Xe-FµTP
The soft ionization mechanism of helium-based plasma seems to be understood while it still remains challenging in argon-ba...
A flexible glucose biosensor modified by reduced-swelling and conductive zwitterionic hydrogel enzyme membrane
A flexible glucose biosensor modified by reduced-swelling and conductive zwitterionic hydrogel enzyme membrane
This paper reports a flexible glucose biosensor which is modified by a reduced-swelling and conductive zwitterionic hydrog...
Acetylcholinesterase and butyrylcholinesterase co-immobilized on a copper containing Prussian blue modified electrode for the broad screening of insecticides
Acetylcholinesterase and butyrylcholinesterase co-immobilized on a copper containing Prussian blue modified electrode for the broad screening of insecticides
We have developed a bienzymatic biosensor that contains acetylcholinesterase together with butyrylcholinesterase co-immobi...
Soft ionization mechanisms in flexible µ-tube plasma—from FµTP to closed µ-tube plasma
Soft ionization mechanisms in flexible µ-tube plasma—from FµTP to closed µ-tube plasma
In order to find an explanation for the mechanism in a plasma operated with an alternating voltage, or rather a square wav...
Binding studies of promethazine and its metabolites with human serum albumin by high-performance affinity chromatography and molecular docking in the presence of codeine
Binding studies of promethazine and its metabolites with human serum albumin by high-performance affinity chromatography and molecular docking in the presence of codeine
“Purple Drank”, a soft drink containing promethazine (PMZ) and codeine (COD), has gained global popularity for...
Reliable biological and multi-omics research through biometrology
Reliable biological and multi-omics research through biometrology
Metrology is the science of measurement and its applications, whereas biometrology is the science of biological measuremen...
Gold nanomaterials: important vectors in biosensing of breast cancer biomarkers
Gold nanomaterials: important vectors in biosensing of breast cancer biomarkers
Breast cancer (BC) is one of the most common malignant tumors in women worldwide, and its incidence is increasing every ye...
Fluorescent carbon dots for discriminating cell types: a review
Fluorescent carbon dots for discriminating cell types: a review
Carbon dots (CDs) are quasi-spherical carbon nanoparticles with excellent photoluminescence, good biocompatibility, favora...
Advanced tools for molecular characterization of bio-based and biodegradable polymers
Advanced tools for molecular characterization of bio-based and biodegradable polymers
Bio-based and biodegradable materials play a vital role in a sustainable and green economy. These materials must exhibit p...
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