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Deep phenotyping of miRNAs in exercise-induced cardiac hypertrophy and fibrosis
Deep phenotyping of miRNAs in exercise-induced cardiac hypertrophy and fibrosis
Cardiac hypertrophy (CH) is an adaptational enlargement of the myocardium, in exposure to altered stress conditions or in ...
A novel model for eggs like pears: How to quantify them geometrically with a mathematical formula of two parameters?
A novel model for eggs like pears: How to quantify them geometrically with a mathematical formula of two parameters?
Of the variety of bird egg shapes, perhaps the most fascinating and unusual are pyriform (pear-shaped, or conical) eggs. A...
Ultradian rhythms: Life’s dance to the music of time*
Ultradian rhythms: Life’s dance to the music of time*
Aon MA, Roussel MR, Cortassa S, et al. 2008 The scale-free dynamics of eukaryotic cells. PLoS One 3 e3624Article  PubM...
pH-influenced self-assembled stealth nanoscaffolds encapsulating memantine for treatment of Alzheimer’s disease
pH-influenced self-assembled stealth nanoscaffolds encapsulating memantine for treatment of Alzheimer’s disease
Alzheimer’s disease (AD) is the most common neurological disorder characterized by the accumulation of β-amyloi...
A tough nut to crack? Proficiency in coconut processing of the Nicobar long-tailed macaque Macaca fascicularis umbrosus
A tough nut to crack? Proficiency in coconut processing of the Nicobar long-tailed macaque Macaca fascicularis umbrosus
The ability to manipulate objects enables macaques to utilize resources well. Coconut (Cocos nucifera) is one such food th...
Construction of a risk model based on N6-methyladenosine-related lncRNAs for predicting the prognosis of breast cancer
Construction of a risk model based on N6-methyladenosine-related lncRNAs for predicting the prognosis of breast cancer
N6-methyladenosine modification and lncRNAs are closely related to the prognosis and immunotherapy response of breast canc...
Metabolic modelling revealed source–sink interactions between four segments of Setaria viridis leaves
Metabolic modelling revealed source–sink interactions between four segments of Setaria viridis leaves
As in most plants, during their growth from immature to mature stages, the leaves of Setaria viridis, a model C4 bioenergy...
ACE2 inhibits proliferation of smooth muscle cell through AT1R and its downstream signaling pathway
ACE2 inhibits proliferation of smooth muscle cell through AT1R and its downstream signaling pathway
To investigate the effect of the angiotensin converting enzyme 2 (ACE2) on AT1R expression, ERK1/2 and STAT3 protein phosp...
Rethinking economic theories of plant water use
Rethinking economic theories of plant water use
An Y-D, Roddy AB, Zhang T-H, et al. 2023 Hydraulic differences between flowers and leaves are driven primarily by pressure...
A physical tug-of-war and the evolution of immune cells
A physical tug-of-war and the evolution of immune cells
Arya G 2016 Models for recovering the energy landscape of conformational transitions from single-molecule pulling experime...
Human small-intestinal gluten-degrading bacteria and its potential implication in celiac disease
Human small-intestinal gluten-degrading bacteria and its potential implication in celiac disease
Celiac disease (CeD) is an immune-mediated chronic disorder triggered by the ingestion of wheat gluten in genetically pred...
Developmental programming–ageing effects in muscle strength of obese rat offspring in a sex-dependent manner
Developmental programming–ageing effects in muscle strength of obese rat offspring in a sex-dependent manner
Maternal obesity programs the offspring to metabolic dysfunction. However, the effects of maternal obesity on skeletal mus...
ASPM overexpression enhances cellular proliferation and migration and predicts worse prognosis for papillary renal cell carcinoma
ASPM overexpression enhances cellular proliferation and migration and predicts worse prognosis for papillary renal cell carcinoma
Various studies have recognized the vital role of the abnormal spindle microtubule assembly (ASPM) gene in the progression...
Regulation of the Scar/WAVE complex in migrating cells: A summary of our understanding
Regulation of the Scar/WAVE complex in migrating cells: A summary of our understanding
Eukaryotic cell migration requires continuous supply of actin polymers at the leading edges to make and extend lamellipodi...
Beauty in biology: An empirical assessment
Beauty in biology: An empirical assessment
‘Beauty’ is not a word typically associated with science. Nevertheless, numerous scientists in recent years ha...
What distinguishes the elephant from E. coli: Causal spreading and the biological principles of metazoan complexity 
What distinguishes the elephant from E. coli: Causal spreading and the biological principles of metazoan complexity 
Agelopoulos M, Foutadakis S and Thanos D 2021 The causes and consequences of spatial organization of the genome in regulat...
Ecosystem carbon stocks and sequestration rates in white oak forests in the central Himalaya: Role of nitrogen-fixing Nepalese alder
Ecosystem carbon stocks and sequestration rates in white oak forests in the central Himalaya: Role of nitrogen-fixing Nepalese alder
Nitrogen-fixing Nepalese alder (Alnus nepalensis D. Don.), a pioneer species and nurse tree species, forms pure stands, an...
Bioplastics from waste biomass of marine and poultry industries
Bioplastics from waste biomass of marine and poultry industries
Plastics are indispensable and typically derived from non-renewable sources. The extensive production and indiscriminate u...
Malabaricone C, a constituent of spice Myristica malabarica, exhibits anti-inflammatory effects via modulation of cellular redox
Malabaricone C, a constituent of spice Myristica malabarica, exhibits anti-inflammatory effects via modulation of cellular redox
The present study primarily focuses on the efficacy of Malabaricone C (Mal C) as an anti-inflammatory agent. Mal C inhibit...
Geographic distribution of two Montivipera taxa using ecological niche modeling
Geographic distribution of two Montivipera taxa using ecological niche modeling
Ecological niche modeling predicts the potential distribution areas of species and contributes to measuring the niche diff...
Appearing and disappearing acts of cilia
Appearing and disappearing acts of cilia
The past few decades have seen a rise in research on vertebrate cilia and ciliopathy, with interesting collaborations betw...
Antixenosis by a resistant Musa cultivar to stem borer Odoiporus longicollis attack and expression of microsomal α-amylase by the pest
Antixenosis by a resistant Musa cultivar to stem borer Odoiporus longicollis attack and expression of microsomal α-amylase by the pest
Banana pseudo-stem weevil (BPW) Odoiporus longicollis Olivier is a serious pest of Musa cultivars which completes its life...
Microbiota-dependent presence of murine enteric glial cells requires myeloid differentiation primary response protein 88 signaling
Microbiota-dependent presence of murine enteric glial cells requires myeloid differentiation primary response protein 88 signaling
Enteric glial cells (EGCs) were shown to maintain the barrier integrity and immune homeostasis of the bowel. Postnatally, ...
Another step towards a unifying theory for ecosystems?
Another step towards a unifying theory for ecosystems?
Allen AP, Brown JH and Gillooly JF 2002 Global biodiversity, biochemical kinetics, and the energetic-equivalence rule. S...
An evolutionarily conserved mechanism underlies interspecies cell–cell signalling in fungi
An evolutionarily conserved mechanism underlies interspecies cell–cell signalling in fungi
Fleißner A, Leeder AC, Roca MG, et al. 2009 Oscillatory recruitment of signaling proteins to cell tips promotes coordinate...
E2F1-mediated up-regulation of TOP2A promotes viability, migration, and invasion, and inhibits apoptosis of gastric cancer cells
E2F1-mediated up-regulation of TOP2A promotes viability, migration, and invasion, and inhibits apoptosis of gastric cancer cells
Previous studies have reported that E2F transcription factor 1 (E2F1) and DNA topoisomerase II alpha (TOP2A) are up-regula...
Effects of oxidative stress caused by iron overload on arachidonic acid metabolites in MES23.5 cells
Effects of oxidative stress caused by iron overload on arachidonic acid metabolites in MES23.5 cells
Iron overload can induce oxidative stress, thereby inducing cell peroxidation. Arachidonic acid (ARA) is widely expressed ...
Emergent properties of coupled bistable switches
Emergent properties of coupled bistable switches
Understanding the dynamical hallmarks of network motifs is one of the fundamental aspects of systems biology. Positive fee...
Antipredator responses of Indosylvirana indica tadpoles do not match the level of predation risk
Antipredator responses of Indosylvirana indica tadpoles do not match the level of predation risk
Predators are the key regulators of prey populations in different environments. However, they are not always present but o...