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Predicting and reducing potential parasite infection between migratory livestock and resident Asiatic ibex of Pin valley, India
Predicting and reducing potential parasite infection between migratory livestock and resident Asiatic ibex of Pin valley, India
Disease cross-transmission between wild and domestic ungulates can negatively impact livelihoods and wildlife conservation...
A study on expression of GRP78 and CHOP in neutrophil endoplasmic reticulum and their relationship with neutrophil apoptosis in the development of sepsis
A study on expression of GRP78 and CHOP in neutrophil endoplasmic reticulum and their relationship with neutrophil apoptosis in the development of sepsis
We investigated the relationship between neutrophil apoptosis and endoplasmic reticulum stress (ERS) in sepsis and its mec...
Visual plant anatomy: From science to education and vice versa
Visual plant anatomy: From science to education and vice versa
Plant biology, mainly plant anatomy, is a less attractive area for students at high school and university, but not much re...
Tumor cell type and gene marker identification by single layer perceptron neural network on single-cell RNA sequence data
Tumor cell type and gene marker identification by single layer perceptron neural network on single-cell RNA sequence data
Tumors have drawn increasing attention recently because of their heterogeneous interior structures. Particularly, single-c...
Crosstalk between photosynthesis and respiration in microbes
Crosstalk between photosynthesis and respiration in microbes
Phototrophic organisms harbor two main bioenergetic hubs, photosynthesis and respiration, and these processes dynamically ...
Role of mitochondria and chloroplasts during stomatal closure: Subcellular location of superoxide and H2O2 production in guard cells of Arabidopsis thaliana
Role of mitochondria and chloroplasts during stomatal closure: Subcellular location of superoxide and H2O2 production in guard cells of Arabidopsis thaliana
Stomatal guard cells are unique in that they have more mitochondria than chloroplasts. Several reports emphasized the impo...
From sequence to consequence: Deciphering the complex cis-regulatory landscape
From sequence to consequence: Deciphering the complex cis-regulatory landscape
Cell type-specific expression of genes plays a pivotal role in the development and evolution of multicellular organisms ov...
Cobra (Naja naja) venom L-amino acid oxidase (NNLAAO70) induces apoptosis and secondary necrosis in human lung epithelial cancer cells
Cobra (Naja naja) venom L-amino acid oxidase (NNLAAO70) induces apoptosis and secondary necrosis in human lung epithelial cancer cells
Snake venom L-amino acid oxidases (LAAOs) are flavoenzymes with diverse physiological and pharmacological effects. These e...
Finding identical sequence repeats in multiple protein sequences: An algorithm
Finding identical sequence repeats in multiple protein sequences: An algorithm
In recent years, several experimental evidences suggest that amino acid repeats are closely linked to many disease conditi...
Dynein functions in galectin-3 mediated processes of clathrin-independent endocytosis
Dynein functions in galectin-3 mediated processes of clathrin-independent endocytosis
Multiple endocytic processes operate in cells in tandem to uptake multiple cargoes involved in diverse cellular functions,...
Enhancing access to treatment for Gaucher disease in India: The need for indigenous manufacturing
Enhancing access to treatment for Gaucher disease in India: The need for indigenous manufacturing
Gaucher disease (GD) is a prevalent lysosomal storage disorder (LSD) that significantly impacts individuals’ lives. ...
Spinal muscular atrophy: Molecular mechanism of pathogenesis, diagnosis, therapeutics, and clinical trials in the Indian context
Spinal muscular atrophy: Molecular mechanism of pathogenesis, diagnosis, therapeutics, and clinical trials in the Indian context
Spinal muscular atrophy (SMA) is a neuromuscular, rare genetic disorder caused due to loss-of-function mutations in the su...
Recent developments in gene therapy research in India
Recent developments in gene therapy research in India
Inherited genetic disorders are progressive in nature and lead to organ dysfunction or death in severe cases. At present, ...
Understanding pathophysiology of GNE myopathy and current progress towards drug development
Understanding pathophysiology of GNE myopathy and current progress towards drug development
GNE myopathy is a rare genetic neuromuscular disease that is caused due to mutations in the GNE gene responsible for siali...
Orphan drug development: Challenges, regulation, and success stories
Orphan drug development: Challenges, regulation, and success stories
Rare diseases, also known as orphan diseases, are diseases with low occurrence in the population. Developing orphan drugs ...
mRNA biotherapeutics landscape for rare genetic disorders
mRNA biotherapeutics landscape for rare genetic disorders
The medical emergency of COVID-19 brought to the forefront mRNA vaccine technology where the mRNA vaccine candidates mRNA-...
Rare genetic disorders in India: Current status, challenges, and CRISPR-based therapy
Rare genetic disorders in India: Current status, challenges, and CRISPR-based therapy
Rare genetic diseases are a group of life-threatening disorders affecting significant populations worldwide and p...
Rare genetic diseases in India: Steps toward a nationwide mission program
Rare genetic diseases in India: Steps toward a nationwide mission program
Rare genetic diseases are rare by themselves with prevalence of 1 in 25,000, but collectively they are a significant cause...
Decoding the mitochondria without a code: mechanistic insights into mitochondrial DNA depletion syndromes
Decoding the mitochondria without a code: mechanistic insights into mitochondrial DNA depletion syndromes
Mitochondrial DNA depletion syndromes (MDS) encompass a wide spectrum of rare genetic disorders caused by severe reduction...
Leaf and tree age-related changes in leaf ecophysiological traits, nutrient, and adaptive strategies of Alnus nepalensis in the central Himalaya
Leaf and tree age-related changes in leaf ecophysiological traits, nutrient, and adaptive strategies of Alnus nepalensis in the central Himalaya
Leaf ecophysiological traits are known to change with leaf and tree age. In the present study, we measured the effect of l...
Screening of quinoa (Chenopodium quinoa Willd.) germplasms under high-SAR saline water on the basis of growth, yield, and multivariate analysis
Screening of quinoa (Chenopodium quinoa Willd.) germplasms under high-SAR saline water on the basis of growth, yield, and multivariate analysis
Increasing soil and underground water salinization with decreasing availability of fresh water has become a potential thre...
Solastalgia, our deteriorating environment, and Spirit of Place
Solastalgia, our deteriorating environment, and Spirit of Place
Climate anxiety is as newly recognised a phenomenon as is the neologism solastalgia. ...
Assessment of seed- and seedling-related traits in Santalum album (Indian sandalwood) reveals high adaptive potential
Assessment of seed- and seedling-related traits in Santalum album (Indian sandalwood) reveals high adaptive potential
Seed and seedling traits govern plant fitness and persistence and are influenced by the interaction between the plant and ...
A novel search engine for proteins involved in Notch crosstalk signaling pathways
A novel search engine for proteins involved in Notch crosstalk signaling pathways
To regulate biological activity in humans, the Notch signaling pathway (NSP) plays an essential role in a wide array of ce...
Helicobacter pylori infection and gut microbiota in adolescents: Is there a relation?
Helicobacter pylori infection and gut microbiota in adolescents: Is there a relation?
Helicobacter pylori infection is a prevalent global infection associated with several complications such as peptic ulcer, ...
The first embryo, the origin of cancer and animal phylogeny. II. The neoplastic process as an evolutionary engine
The first embryo, the origin of cancer and animal phylogeny. II. The neoplastic process as an evolutionary engine
In this article, I put forward the idea that the neoplastic process (NP) has deep evolutionary roots and makes specific pr...
Identification and investigation of barley powdery mildew (Blumeria graminis f. sp. tritici) infection in winter wheat with conventional stress reactions and non-invasive biophoton emission parameters
Identification and investigation of barley powdery mildew (Blumeria graminis f. sp. tritici) infection in winter wheat with conventional stress reactions and non-invasive biophoton emission parameters
The objective of this study was to characterize the effects of barley powdery mildew infection on wheat via the evolution ...
Molecular transformations and self-association in anthocyanin pigment patterns
Molecular transformations and self-association in anthocyanin pigment patterns
Spatial patterns of red, purple, and blue colors due to plant pigments called anthocyanins appear in a wide variety of flo...
Exacerbation of drought-induced physiological and biochemical changes in leaves of Pisum sativum upon restriction of COX and AOX pathways of mitochondrial oxidative electron transport
Exacerbation of drought-induced physiological and biochemical changes in leaves of Pisum sativum upon restriction of COX and AOX pathways of mitochondrial oxidative electron transport
Drought stress affects photosynthesis, leading to significant decrease in crop productivity. In the current study, the imp...
Involvement of oxidative stress in localization of bacterial spot infection in pepper plants
Involvement of oxidative stress in localization of bacterial spot infection in pepper plants
Xanthomonas euvesicatoria is a major cause of bacterial spot disease in various crops. The present study was focused on th...
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