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Chapter Eleven - Cryo-EM technique and its application: Structure of steroid hormone receptors
Chapter Eleven - Cryo-EM technique and its application: Structure of steroid hormone receptors
For decades, mechanistic understandings of how macromolecular complexes involving transcription factor proteins fulfill th...
Chapter Twelve - Structure and functions of the N-terminal domain of steroid hormone receptors
Chapter Twelve - Structure and functions of the N-terminal domain of steroid hormone receptors
The steroid hormone receptors (SHRs), which include receptors for glucocorticoid-, estrogen, progesterone, and mineralocor...
Chapter Thirteen - The human glucocorticoid receptor
Chapter Thirteen - The human glucocorticoid receptor
Glucocorticoids, such as cortisol in humans and corticosterone in rodents, are biosynthesized in the intermediate cellular...
Chapter Fourteen - The androgen receptor
Chapter Fourteen - The androgen receptor
Androgens are C19 steroids that are male sex hormones responsible for differentiation and maintenance of the male genitali...
Chapter Fifteen - Steroid-receptor coactivator complexes in thyroid hormone-regulation of Xenopus metamorphosis
Chapter Fifteen - Steroid-receptor coactivator complexes in thyroid hormone-regulation of Xenopus metamorphosis
Ever since the discovery that one or more compounds in the thyroid could accelerate anuran metamorphosis over a century ag...
Chapter Sixteen - Essential and subtype-dependent function of thyroid hormone receptors during Xenopus metamorphosis
Chapter Sixteen - Essential and subtype-dependent function of thyroid hormone receptors during Xenopus metamorphosis
Thyroid hormone (T3) have broad and diverse effects in vertebrates. It affects metabolisms in different organs and regulat...
Chapter Seventeen - Steroid hormone signaling: What we can learn from insect models
Chapter Seventeen - Steroid hormone signaling: What we can learn from insect models
Ecdysteroids are a group of steroid hormones in arthropods that were originally identified as molting hormones in insects ...
Chapter Eighteen - Membrane estrogen receptor and follicle-stimulating hormone receptor
Chapter Eighteen - Membrane estrogen receptor and follicle-stimulating hormone receptor
Two phylogenetically distantly-related IncF plasmids, F and pED208, serve as important models for mechanistic and structur...
Chapter Nineteen - Structure-function of DHEA binding proteins
Chapter Nineteen - Structure-function of DHEA binding proteins
Dehydroepiandrosterone (3β-hydroxy-5-androsten-17-one, DHEA, PubChem CID 5881) is a cholesterol-derived steroid synthesize...
Chapter Twenty - Juvenile hormone receptor Methoprene tolerant: Functions and applications
Chapter Twenty - Juvenile hormone receptor Methoprene tolerant: Functions and applications
Insect steroid hormones, ecdysteroids (20 hydroxyecdysone, 20E is the most active form and referred to as ecdysone) and se...
Chapter Twenty-One - Structural dynamics of chemokine receptors
Chapter Twenty-One - Structural dynamics of chemokine receptors
To identify clinical factors (physical and psychological symptoms and post-traumatic growth) that predict social participa...
A cholesterol-centric outlook on steroidogenesis
A cholesterol-centric outlook on steroidogenesis
Cholesterol, an essential and versatile lipid, is the precursor substrate for the biosynthesis of steroid hormones, and a ...
Growth hormone receptor gene disruption
Growth hormone receptor gene disruption
While best known for the ability to stimulate longitudinal bone growth during puberty, growth hormone (GH) is a pleiotropi...
The androgen receptor
The androgen receptor
Androgens are C19 steroids that are male sex hormones responsible for differentiation and maintenance of the male genitali...
MicroRNAs in aldosterone production and action
MicroRNAs in aldosterone production and action
Available online 14 August 2023Author links open overlay panel, , , , , , AbstractAldosterone is a cardiovascular hormone ...
Serotonin and the serotonin transporter in the adrenal gland
Serotonin stimulation of corticosteroid secretion is mediated by 5-HT receptors, requires cAMP production, PKA activation,...
Current insight into the transient X-zone in the adrenal gland cortex
Available online 12 July 2023Author links open overlay panel, , , AbstractMouse models have been widely used in the study ...
The human glucocorticoid receptor
Glucocorticoids, such as cortisol in humans and corticosterone in rodents, are biosynthesized in the intermediate cellular...
Regulation of lipid droplets and cholesterol metabolism in adrenal cortical cells
The adrenal gland is composed of two distinctly different endocrine moieties. The interior medulla consists of neuroendocr...
Signaling mechanism of growth hormone-releasing hormone receptor
Available online 7 July 2023Author links open overlay panel, , , AbstractThe hypothalamic peptide growth hormone-releasing...
Structural dynamics of chemokine receptors
Membrane proteins such as G protein-coupled receptors (GPCRs) are involved in awide range of physiological and pathologica...
Adaptive remodeling of the stimulus-secretion coupling: Lessons from the ‘stressed’ adrenal medulla
Our organism is daily subjected to environmental changes that challenge body homeostasis. These changes are often perceive...
Genomically anchored vitamin D receptor mediates an abundance of bioprotective actions elicited by its 1,25-dihydroxyvitamin D hormonal ligand
The initial observation that illuminated the existence of VDR was published in the Journal of Biological Chemistry (Haussl...
The three-dimensional structure of insulin and its receptor
Available online 5 June 2023Author links open overlay panelAbstractInsulin is a peptide hormone essential for maintaining ...
Angiotensin II-dependent aldosterone production in the adrenal cortex
The adrenal cortex is responsible for adrenal steroid production and is anatomically divided into three distinct zones pro...
Functional interaction of Clock genes and bone morphogenetic proteins in the adrenal cortex
The hypothalamic-pituitary-adrenal (HPA) axis, which mediates the adaptive responses to stressors, is essential for the su...
Juvenile hormone receptor Methoprene tolerant: Functions and applications
Insect steroid hormones, ecdysteroids (20 hydroxyecdysone, 20E is the most active form and referred to as ecdysone) and se...
Hepcidin and its multiple partners: Complex regulation of iron metabolism in health and disease
Iron is an essential element for almost all living organisms, from unicellular organisms to mammals. It forms the core of ...
Cryo-EM technique and its application: Structure of steroid hormone receptors
For decades, mechanistic understandings of how macromolecular complexes involving transcription factor proteins fulfill th...
Structure and functions of the N-terminal domain of steroid hormone receptors
The steroid hormone receptors (SHRs), which include receptors for glucocorticoid-, estrogen, progesterone, and mineralocor...
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