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The natural product-derived JM-9 alleviates high-fat diet-induced fatty liver in mice by targeting MD2
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Urolithin A alleviates NLRP3 inflammasome activation and pyroptosis by promoting microglial mitophagy following spinal cord injury
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TFAP4 regulates the progression of liver fibrosis through the STING signaling pathway
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Sinensetin attenuates LPS-induced acute pulmonary inflammation in mice and RAW264.7 cells by modulating NF-κB p65-mediated immune resistance and STAT3-mediated tissue resilience
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Protective effect and mechanism of plant-derived Lactobacillus G11 on septic myocardial injury
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Interferon regulatory factor 5 attenuates kidney fibrosis through transcriptional suppression of Tgfbr1
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Inhibition of STAT3 phosphorylation attenuates perioperative neurocognitive disorders in mice with D-galactose-induced aging by regulating pro-inflammatory reactive astrocytes
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Plumbagin improves myocardial fibrosis after myocardial infarction by inhibiting the AKT/mTOR pathway to upregulate autophagy levels
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Microglia-derived exosomal ciRS-7 mediates IL-17A effect of promoting neurodegeneration via miR-7 and SNCA targets in an experimental Parkinson’s disease
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Downregulation of CCR2 reduces ventricular remodeling after myocardial infarction by splenic nerve neuromodulation in acute and chronic rat models
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Regulated programmed cell death in sepsis associated acute lung injury: From pathogenesis to therapy
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Identification and validation VAT1 in gastric cancer through bioinformatics and experimental analysis
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Innate and SARS-CoV-2 specific adaptive immune response kinetic in neutralizing monoclonal antibody successfully treated COVID-19 patients
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Heterologous Prime-Boost immunization with Adenoviral vector and recombinant subunit vaccines strategies against dengue virus type2
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THSWD upregulates the LTF/AMPK/mTOR/Becn1 axis and promotes lysosomal autophagy in hepatocellular carcinoma cells by regulating gut flora and metabolic reprogramming
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House dust mite induced mucosal barrier dysfunction and type 2 inflammatory responses via the MAPK/AP-1/IL-24 Signaling pathway in allergic rhinitis
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Advanced oxidation protein products induce apoptosis in thyroid follicular epithelial cells through oxidative stress in Hashimoto’s thyroiditis
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Gut microbial metabolite indole-3-propionic acid alleviates polycystic ovary syndrome in mice by regulating the AhR-NLRP3 axis
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Betulinic acid mitigates lipopolysaccharide-induced intestinal injury of weaned piglets through modulation of the mitochondrial quality control
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PD1-TLR10 fusion protein enhances the antitumor efficacy of CAR-T cells in colon cancer
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Analysis of the efficacy of Langhans giant cells in controlling cutaneous Mycobacterium marinum infections
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d-Limonene inhibits cytokines and chemokines expression by regulating NF-kappaB and STAT in HaCat cells and DNCB-induced atopic dermatitis in BALB/c mice
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Chitosan oligosaccharides ameliorates maternal diabetes-induced embryonic neural tube defects via inhibitting excessive pyroptosis of neuroepithelial cells
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YAP promotes fibrosis by regulating macrophage to myofibroblast transdifferentiation and M2 polarization in chronic pancreatitis
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The roles and therapeutic potential of exosomal non-coding RNAs in microglia-mediated intercellular communication
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Extracellular peroxiredoxin 6 released from alveolar epithelial cells as a DAMP drives macrophage activation and inflammatory exacerbation in acute lung injury
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Oleandrin inhibits osteoclast differentiation by targeting the LRP4/MAPK/NF-κB signalling pathway to treat osteoporosis
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Skin inflammation and lipid disorder induced by topical application of Mal f 1
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Application of nanoparticles with activating STING pathway function in tumor synergistic therapy
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Esmolol upregulates the α7 nAChR/STAT3/NF-κB pathway by decreasing the ubiquitin and increasing the ChAT+CD4+ T lymphocyte to alleviate inflammation in septic cardiomyopathy
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