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The expanding repertoire of brain–computer interfaces
The expanding repertoire of brain–computer interfaces
Brain–computer interfaces are expanding from functional to recreational applications, as evidenced by a study in whi...
Prenatal blood tests can reveal maternal cancer
Prenatal blood tests can reveal maternal cancer
A study detected hidden cancers in almost half of all pregnant people who were referred for cancer screening following an ...
A high-performance brain–computer interface for finger decoding and quadcopter game control in an individual with paralysis
A high-performance brain–computer interface for finger decoding and quadcopter game control in an individual with paralysis
People with paralysis express unmet needs for peer support, leisure activities and sporting activities. Many within the ge...
Author Correction: Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids
These authors contributed equally: Mattia Francesco Maria Gerli, Giuseppe Calà.Department of Surgical Biotechnology, Divis...
Our Future Health: a unique global resource for discovery and translational research
Our Future Health: a unique global resource for discovery and translational research
Our Future Health has recruited more than 1 million participants in the UK, with biobanked bloods, making it the largest c...
Neoadjuvant nivolumab and chemotherapy in early estrogen receptor-positive breast cancer: a randomized phase 3 trial
Neoadjuvant nivolumab and chemotherapy in early estrogen receptor-positive breast cancer: a randomized phase 3 trial
Patients with estrogen receptor-positive (ER+), human epidermal growth factor receptor 2-negative (HER2−) primary br...
Pembrolizumab and chemotherapy in high-risk, early-stage, ER+/HER2− breast cancer: a randomized phase 3 trial
Pembrolizumab and chemotherapy in high-risk, early-stage, ER+/HER2− breast cancer: a randomized phase 3 trial
Addition of pembrolizumab to neoadjuvant chemotherapy followed by adjuvant pembrolizumab improved outcomes in patients wit...
Data sharing restrictions are hampering precision health in the European Union
Competing interests C.L.Q. received consultancy fees from Pfizer; honoraria, tra...
How patient advocates influence health policy
How patient advocates influence health policy
Scientists can learn the power of storytelling and coalition-building from patient advocates.
Clinically useful obesity subtypes revealed by harnessing deviations from population-average risk
Clinically useful obesity subtypes revealed by harnessing deviations from population-average risk
Obesity is associated with many life-threatening comorbidities. Its heterogeneous risk profile makes the prevention of obe...
Somatic CAG repeat expansion in blood associates with biomarkers of neurodegeneration in Huntington’s disease decades before clinical motor diagnosis
Somatic CAG repeat expansion in blood associates with biomarkers of neurodegeneration in Huntington’s disease decades before clinical motor diagnosis
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease with the age at which characteristic sy...
Global health engagement strengthens US security, prosperity and leadership
Discover the world’s best science and medicine | Nature.com
Menstrual cycle linked to breast cancer chemotherapy response
Menstrual cycle linked to breast cancer chemotherapy response
According to preclinical studies and a retrospective clinical analysis, the menstrual cycle may influence the breast cance...
Donor-derived GD2-specific CAR T cells in relapsed or refractory neuroblastoma
Donor-derived GD2-specific CAR T cells in relapsed or refractory neuroblastoma
Allogeneic chimeric antigen receptor (CAR) T cells targeting disialoganglioside-GD2 (ALLO_GD2-CART01) could be a therapeut...
Publisher Correction: Partitioned polygenic risk scores identify distinct types of metabolic dysfunction-associated steatotic liver disease
Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, Wallenberg Laboratory, Universi...
How citizen scientists and community engagement boost the impact of health research
How citizen scientists and community engagement boost the impact of health research
With the Declaration of Helsinki now mandating community engagement, Nature Medicine asks three winners of the Nature Awar...
Health AI poses distinct harms and potential benefits for disabled people
Adamson, A. S. & Smith, A. JAMA Dermatol. 154, 1247–1248 (2018).Article  PubMed  Google S...
In vivo base editing extends lifespan of a humanized mouse model of prion disease
In vivo base editing extends lifespan of a humanized mouse model of prion disease
Prion disease is a fatal neurodegenerative disease caused by the misfolding of prion protein (PrP) encoded by the PRNP gen...
Oral obeldesivir provides postexposure protection against Marburg virus in nonhuman primates
The recent outbreak of Marburg virus (MARV) in Rwanda underscores the need for effective countermeasures against this high...
Author Correction: Ferric carboxymaltose for anemia in late pregnancy: a randomized controlled trial
Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, AustraliaSant-Rayn Pasricha, Ricardo Ataíde, Reb...
Differences in the lifetime risk and population burden of dementia
Differences in the lifetime risk and population burden of dementia
Dementia is a major public health burden, and determining its lifetime risk is essential to inform prevention strategies. ...
Lifetime risk and projected burden of dementia
Lifetime risk and projected burden of dementia
Understanding the lifetime risk of dementia can inform public health planning and improve patient engagement in prevention...
Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma
Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma
Circulating tumor DNA (ctDNA) detection can predict clinical risk in early-stage tumors. However, clinical applications ar...
RNA gene therapies offer hope for millions with high cholesterol
RNA gene therapies offer hope for millions with high cholesterol
Base editing, antisense oligonucleotides and siRNA therapies that target low-density lipoprotein and the genes encoding mo...
Premarital genomic screening in Arab populations of the Middle East
Premarital genomic screening can help curb the burden of rare recessive disorders in populations with high rates of consan...
Impact of RSVpreF vaccination on reducing the burden of respiratory syncytial virus in infants and older adults
Impact of RSVpreF vaccination on reducing the burden of respiratory syncytial virus in infants and older adults
Respiratory syncytial virus (RSV) causes a substantial health burden among infants and older adults. Prefusion F pro...
Visualizing the effects and causes of caregiver deaths on children in the USA
Visualizing the effects and causes of caregiver deaths on children in the USA
Death of caregivers threaten child wellbeing. We estimate that 2.91 million children and adolescents in the USA had experi...
Autologous macrophage therapy for liver cirrhosis: a phase 2 open-label randomized controlled trial
Autologous macrophage therapy for liver cirrhosis: a phase 2 open-label randomized controlled trial
Cirrhosis is a major cause of morbidity and mortality; however, there are no approved therapies except orthotopic liver tr...
Subcutaneous weekly semaglutide with automated insulin delivery in type 1 diabetes: a double-blind, randomized, crossover trial
Subcutaneous weekly semaglutide with automated insulin delivery in type 1 diabetes: a double-blind, randomized, crossover trial
Efforts to improve glycemic control in type 1 diabetes are ongoing. We performed a randomized, double-blind, crossover tri...
Orphanhood and caregiver death among children in the United States by all-cause mortality, 2000–2021
Orphanhood and caregiver death among children in the United States by all-cause mortality, 2000–2021
Deaths of parents and grandparent caregivers threaten child well-being owing to losses of care, financial support, safety ...
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