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Where Are All the Women in Industry Advisory Boards?
Where Are All the Women in Industry Advisory Boards?
In this article academic and industry professionals partner to explore the causes and consequences of gender & other d...
High-Dose Cytarabine and Autologous Stem-Cell Transplantation in Mantle Cell Lymphoma: Long-Term Follow-Up of the Randomized Mantle Cell Lymphoma Younger Trial of the European Mantle Cell Lymphoma Network
High-Dose Cytarabine and Autologous Stem-Cell Transplantation in Mantle Cell Lymphoma: Long-Term Follow-Up of the Randomized Mantle Cell Lymphoma Younger Trial of the European Mantle Cell Lymphoma Network
Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based...
Guilt and Gratitude
Guilt and Gratitude
Guilt and Gratitude: Guilt surrounding toxic consequences of chemotherapy and gratitude to patients for acknowledging the ...
Dissecting the Need for Adjuvant Therapy in Patients With Early-Stage Melanoma With Micrometastases
Dissecting the Need for Adjuvant Therapy in Patients With Early-Stage Melanoma With Micrometastases
© 2022 by American Society of Clinical OncologyAUTHOR'S DISCLOSURES OF POTENTIAL CONFLICTS OF INTERESTDissecting the Need ...
Line by Line: Distinct Patterns of Anti-EGFR Antibody Resistance by Line of Therapy
Line by Line: Distinct Patterns of Anti-EGFR Antibody Resistance by Line of Therapy
Line by Line: Distinct Patterns of Anti-EGFR Antibody Resistance by Line of TherapyThe following represents disclosure inf...
Symptom Clusters in Childhood Cancer Survivors
Symptom Clusters in Childhood Cancer Survivors
© 2022 by American Society of Clinical OncologyTHE TAKEAWAYIn the article accompanying this editorial, Shin et al4 describ...
Resistance Mechanisms to Anti–Epidermal Growth Factor Receptor Therapy in RAS/RAF Wild-Type Colorectal Cancer Vary by Regimen and Line of Therapy
Resistance Mechanisms to Anti–Epidermal Growth Factor Receptor Therapy in RAS/RAF Wild-Type Colorectal Cancer Vary by Regimen and Line of Therapy
PURPOSEAcquired resistance to anti–epidermal growth factor receptor (EGFR) inhibitor (EGFRi) therapy in colorectal cancer ...
Adjuvant Endocrine Therapy in Premenopausal Breast Cancer: 12-Year Results From SOFT
Adjuvant Endocrine Therapy in Premenopausal Breast Cancer: 12-Year Results From SOFT
Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based...
Graded Cardiac Response Criteria for Patients With Systemic Light Chain Amyloidosis
Graded Cardiac Response Criteria for Patients With Systemic Light Chain Amyloidosis
PURPOSEBinary cardiac response assessment using cardiac biomarkers is prognostic in light chain amyloidosis. Previous stud...
Redefining Gleason 6 Prostate Cancer Nomenclature: The Surgeon's Perspective
Redefining Gleason 6 Prostate Cancer Nomenclature: The Surgeon's Perspective
AUTHORS' DISCLOSURES OF POTENTIAL CONFLICTS OF INTERESTRedefining Gleason 6 Prostate Cancer Nomenclature: The Surgeon's Pe...
Nivolumab Plus Ipilimumab Versus EXTREME Regimen as First-Line Treatment for Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck: The Final Results of CheckMate 651
Nivolumab Plus Ipilimumab Versus EXTREME Regimen as First-Line Treatment for Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck: The Final Results of CheckMate 651
PURPOSECheckMate 651 (ClinicalTrials.gov identifier: NCT02741570) evaluated first-line nivolumab plus ipilimumab versus EX...
Decitabine Versus Hydroxyurea for Advanced Proliferative Chronic Myelomonocytic Leukemia: Results of a Randomized Phase III Trial Within the EMSCO Network
Decitabine Versus Hydroxyurea for Advanced Proliferative Chronic Myelomonocytic Leukemia: Results of a Randomized Phase III Trial Within the EMSCO Network
PURPOSEHydroxyurea (HY) is a reference treatment of advanced myeloproliferative neoplasms. We conducted a randomized phase...
Rare Germline ATM Variants Influence the Development of Chronic Lymphocytic Leukemia
Rare Germline ATM Variants Influence the Development of Chronic Lymphocytic Leukemia
PURPOSEGermline missense variants of unknown significance in cancer-related genes are increasingly being identified with t...
Coadministration of CD19- and CD22-Directed Chimeric Antigen Receptor T-Cell Therapy in Childhood B-Cell Acute Lymphoblastic Leukemia: A Single-Arm, Multicenter, Phase II Trial
Coadministration of CD19- and CD22-Directed Chimeric Antigen Receptor T-Cell Therapy in Childhood B-Cell Acute Lymphoblastic Leukemia: A Single-Arm, Multicenter, Phase II Trial
PURPOSEWe determined the safety and efficacy of coadministration of CD19- and CD22-chimeric antigen receptor (CAR) T cells...
State Variation in Squamous Cell Carcinoma of the Anus Incidence and Mortality, and Association With HIV/AIDS and Smoking in the United States
State Variation in Squamous Cell Carcinoma of the Anus Incidence and Mortality, and Association With HIV/AIDS and Smoking in the United States
PURPOSESquamous cell carcinoma of the anus (SCCA) incidence and mortality rates are rising in the United States. Understan...
Pembrolizumab Versus Placebo as Second-Line Therapy in Patients From Asia With Advanced Hepatocellular Carcinoma: A Randomized, Double-Blind, Phase III Trial
Pembrolizumab Versus Placebo as Second-Line Therapy in Patients From Asia With Advanced Hepatocellular Carcinoma: A Randomized, Double-Blind, Phase III Trial
PURPOSEWe evaluated the efficacy and safety of pembrolizumab in patients from Asia with previously treated advanced hepato...
High Diagnostic Accuracy of Epigenetic Imprinting Biomarkers in Thyroid Nodules
High Diagnostic Accuracy of Epigenetic Imprinting Biomarkers in Thyroid Nodules
PURPOSETo explore the novel diagnostic value of epigenetic imprinting biomarkers in thyroid nodules.PATIENTS AND METHODSA ...
Prognostic Impact of Early Treatment and Oxaliplatin Discontinuation in Patients With Stage III Colon Cancer: An ACCENT/IDEA Pooled Analysis of 11 Adjuvant Trials
Prognostic Impact of Early Treatment and Oxaliplatin Discontinuation in Patients With Stage III Colon Cancer: An ACCENT/IDEA Pooled Analysis of 11 Adjuvant Trials
PURPOSEOxaliplatin-based adjuvant chemotherapy in patients with stage III colon cancer (CC) for 6 months remains a standar...
The POSEIDON Trial: Will Secondary End Points Change Our Clinical Practice?
The POSEIDON Trial: Will Secondary End Points Change Our Clinical Practice?
The POSEIDON Trial: Will Secondary End Points Change Our Clinical Practice?The following represents disclosure information...
Winning the Battle But Losing the War: Single-Cancer Screening Trials
Winning the Battle But Losing the War: Single-Cancer Screening Trials
"Winning the Battle But Losing the War: Single-Cancer Screening Trials." Journal of Clinical Oncology, , pp. –© 2022 by Am...
Onco-Hypertension: Changing Paradigm of Treating Hypertension in Patients With Cancer
Onco-Hypertension: Changing Paradigm of Treating Hypertension in Patients With Cancer
The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A c...
Phase IIb Randomized, Placebo-Controlled, Dose-Escalating, Double-Blind Study of Cannabidiol Oil for the Relief of Symptoms in Advanced Cancer (MedCan1-CBD)
Phase IIb Randomized, Placebo-Controlled, Dose-Escalating, Double-Blind Study of Cannabidiol Oil for the Relief of Symptoms in Advanced Cancer (MedCan1-CBD)
PURPOSETo determine whether cannabidiol (CBD) oil can improve symptom distress in patients with advanced cancer receiving ...
Risk of Overusing Sentinel Node Biopsy in Patients With Thin Melanoma
Risk of Overusing Sentinel Node Biopsy in Patients With Thin Melanoma
© 2022 by American Society of Clinical OncologyAUTHOR'S DISCLOSURES OF POTENTIAL CONFLICTS OF INTERESTRisk of Overusing Se...
Phase II Randomized Study of Salvage Radiation Therapy Plus Enzalutamide or Placebo for High-Risk Prostate-Specific Antigen Recurrent Prostate Cancer After Radical Prostatectomy: The SALV-ENZA Trial
Phase II Randomized Study of Salvage Radiation Therapy Plus Enzalutamide or Placebo for High-Risk Prostate-Specific Antigen Recurrent Prostate Cancer After Radical Prostatectomy: The SALV-ENZA Trial
PURPOSEWe sought to investigate whether enzalutamide (ENZA), without concurrent androgen deprivation therapy, increases fr...
Addressing Barriers to Clinical Trial Participation for Transgender People With Cancer to Improve Access and Generate Data
Addressing Barriers to Clinical Trial Participation for Transgender People With Cancer to Improve Access and Generate Data
A roadmap for addressing barriers to cancer clinical trial enrollment for transgender people.
Smartphone Psychotherapy Reduces Fear of Cancer Recurrence Among Breast Cancer Survivors: A Fully Decentralized Randomized Controlled Clinical Trial (J-SUPPORT 1703 Study)
Smartphone Psychotherapy Reduces Fear of Cancer Recurrence Among Breast Cancer Survivors: A Fully Decentralized Randomized Controlled Clinical Trial (J-SUPPORT 1703 Study)
PURPOSEFear of cancer recurrence (FCR) is a common distressing condition. We investigated the efficacy of smartphone probl...
Circulating Plasma Cells in Newly Diagnosed Multiple Myeloma: Prognostic and More
Circulating Plasma Cells in Newly Diagnosed Multiple Myeloma: Prognostic and More
Circulating Plasma Cells in Newly Diagnosed Multiple Myeloma: Prognostic and MoreThe following represents disclosure infor...
Treatment of Metastatic Colorectal Cancer: ASCO Guideline
Treatment of Metastatic Colorectal Cancer: ASCO Guideline
PURPOSETo develop recommendations for treatment of patients with metastatic colorectal cancer (mCRC).METHODSASCO convened ...
Learning About Mismatch Repair From a Rare Cancer Syndrome: A LOGICal Step Forward
Learning About Mismatch Repair From a Rare Cancer Syndrome: A LOGICal Step Forward
Learning About Mismatch Repair From a Rare Cancer Syndrome: A LOGICal Step ForwardThe following represents disclosure info...
Preparing for the End Game
Preparing for the End Game
In preparing for the end game, a senior cancer research scientist reflects on his own mortality after his good friend’s il...
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